8V3P
| CCP5 in complex with Glu-P-peptide 2 transition state analog | 分子名称: | Cytosolic carboxypeptidase-like protein 5, Tubulin beta-2A chain, ZINC ION | 著者 | Chen, J, Zehr, E.A, Gruschus, J.M, Szyk, A, Liu, Y, Tanner, M.E, Tjandra, N, Roll-Mecak, A. | 登録日 | 2023-11-28 | 公開日 | 2024-07-17 | 最終更新日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Tubulin code eraser CCP5 binds branch glutamates by substrate deformation. Nature, 631, 2024
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8V4L
| CCP5 in complex with microtubules class2 | 分子名称: | Cytosolic carboxypeptidase-like protein 5, GLUTAMIC ACID, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Chen, J, Zehr, E.A, Gruschus, J.M, Szyk, A, Liu, Y, Tanner, M.E, Tjandra, N, Roll-Mecak, A. | 登録日 | 2023-11-29 | 公開日 | 2024-07-17 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Tubulin code eraser CCP5 binds branch glutamates by substrate deformation. Nature, 631, 2024
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8V55
| Human mitochondrial DNA polymerase gamma bound to a replication fork in an open conformation | 分子名称: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | 著者 | Riccio, A.A, Krahn, J.M, Bouvette, J, Borgnia, M.J, Copeland, W.C. | 登録日 | 2023-11-30 | 公開日 | 2024-07-10 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Coordinated DNA polymerization by Pol gamma and the region of LonP1 regulated proteolysis. Nucleic Acids Res., 52, 2024
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8VON
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8UPY
| Methanosarcine mazei tRNAPyl in A-site of ribosome | 分子名称: | RNA (72-MER) | 著者 | Krahn, N, Zhang, J, Melnikov, S.V, Tharp, J.M, Villa, A, Patel, A, Howard, R.J, Gabir, H, Patel, T.R, Stetefeld, J, Puglisi, J, Soll, D. | 登録日 | 2023-10-23 | 公開日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | tRNA shape is an identity element for an archaeal pyrrolysyl-tRNA synthetase from the human gut. Nucleic Acids Res., 52, 2024
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8VD6
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8BWC
| E. coli BAM complex (BamABCDE) wild-type | 分子名称: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | 著者 | Machin, J.M, Radford, S.E, Ranson, N.A. | 登録日 | 2022-12-06 | 公開日 | 2023-05-24 | 最終更新日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Darobactin B Stabilises a Lateral-Closed Conformation of the BAM Complex in E. coli Cells. Angew.Chem.Int.Ed.Engl., 62, 2023
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1A3K
| X-RAY CRYSTAL STRUCTURE OF THE HUMAN GALECTIN-3 CARBOHYDRATE RECOGNITION DOMAIN (CRD) AT 2.1 ANGSTROM RESOLUTION | 分子名称: | GALECTIN-3, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Seetharaman, J, Kanigsberg, A, Slaaby, R, Leffler, H, Barondes, S.H, Rini, J.M. | 登録日 | 1998-01-22 | 公開日 | 1998-07-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | X-ray crystal structure of the human galectin-3 carbohydrate recognition domain at 2.1-A resolution. J.Biol.Chem., 273, 1998
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5OK3
| Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp241 and Fasudil | 分子名称: | 5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE, UPF0418 protein FAM164A, cAMP-dependent protein kinase catalytic subunit alpha | 著者 | Mueller, J.M, Heine, A, Klebe, G. | 登録日 | 2017-07-25 | 公開日 | 2018-08-08 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.588 Å) | 主引用文献 | Diamondoid Amino Acid-Based Peptide Kinase A Inhibitor Analogues. Chemmedchem, 14, 2019
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8W2J
| Human liver phosphofructokinase-1 filament in the T-state conformation | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent 6-phosphofructokinase, ... | 著者 | Lynch, E.M, Kollman, J.M, Webb, B.A. | 登録日 | 2024-02-20 | 公開日 | 2024-09-11 | 最終更新日 | 2024-09-25 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis for allosteric regulation of human phosphofructokinase-1. Nat Commun, 15, 2024
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8W2G
| Human liver phosphofructokinase-1 in the R-state conformation | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, 6-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Lynch, E.M, Kollman, J.M, Webb, B.A. | 登録日 | 2024-02-20 | 公開日 | 2024-09-11 | 最終更新日 | 2024-09-25 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis for allosteric regulation of human phosphofructokinase-1. Nat Commun, 15, 2024
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1AFS
| RECOMBINANT RAT LIVER 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE (3-ALPHA-HSD) COMPLEXED WITH NADP AND TESTOSTERONE | 分子名称: | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TESTOSTERONE | 著者 | Bennett, M.J, Albert, R.H, Jez, J.M, Ma, H, Penning, T.M, Lewis, M. | 登録日 | 1997-03-13 | 公開日 | 1997-10-08 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Steroid recognition and regulation of hormone action: crystal structure of testosterone and NADP+ bound to 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase. Structure, 5, 1997
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8W2H
| Human liver phosphofructokinase-1 in the T-state conformation | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent 6-phosphofructokinase, ... | 著者 | Lynch, E.M, Kollman, J.M, Webb, B.A. | 登録日 | 2024-02-20 | 公開日 | 2024-09-11 | 最終更新日 | 2024-09-25 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural basis for allosteric regulation of human phosphofructokinase-1. Nat Commun, 15, 2024
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5OTJ
| Monomeric polcalcin (Phl p 7) in complex with two identical allergen-specific antibodies | 分子名称: | 1,2-ETHANEDIOL, 102.1F10 Fab heavy chain, 102.1F10 Fab light chain, ... | 著者 | Mitropoulou, A.N, Davies, A.M, Beavil, A.J, McDonnell, J.M, Sutton, B.J. | 登録日 | 2017-08-22 | 公開日 | 2018-09-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure of a patient-derived antibody in complex with allergen reveals simultaneous conventional and superantigen-like recognition. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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8CPK
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8C7P
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8RFM
| Human NOQ1 enzyme in complex with NADH by serial crystallography | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H dehydrogenase [quinone] 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Martin-Garcia, J.M, Grieco, A, Medina, M, Boneta, S, Pey, A.L. | 登録日 | 2023-12-13 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural dynamics and functional cooperativity of human NQO1 by ambient temperature serial crystallography and simulations. Protein Sci., 33, 2024
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8RFN
| Human NOQ1 enzyme in its holo form by serial crystallography | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H dehydrogenase [quinone] 1 | 著者 | Martin-Garcia, J.M, Grieco, A, Medina, M, Boneta, S, Pey, A.L. | 登録日 | 2023-12-13 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural dynamics and functional cooperativity of human NQO1 by ambient temperature serial crystallography and simulations. Protein Sci., 33, 2024
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8VOL
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8VOM
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1AQT
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8V8Z
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8UH2
| Complex of C3b with the inhibitor albicin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Albicin, Complement C3 beta chain, ... | 著者 | Andersen, J.F, Lei, H, Strayer, E, Ribeiro, J.M. | 登録日 | 2023-10-06 | 公開日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | The mechanism of a mosquito salivary inhibitor of the alternative C3 convertase is elucidated through structural analysis of its complex with C3bBb To Be Published
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8V9B
| Lipoprotein(a) Kringle IV domain 7 - Lp(a) KIV7 in complex with LY3441732 | 分子名称: | (2S,2'S)-3,3'-[carbonylbis(azanediyl-3,1-phenylene)]bis{2-[(3R)-pyrrolidin-1-ium-3-yl]propanoate}, Apolipoprotein(a), MAGNESIUM ION, ... | 著者 | Hendle, J, Weichert, K, Sauder, J.M. | 登録日 | 2023-12-07 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | Discovery of potent small-molecule inhibitors of lipoprotein(a) formation. Nature, 629, 2024
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8URV
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