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PDB: 2129 件

1UO4
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Structure Based Engineering of Internal Molecular Surfaces Of Four Helix Bundles
分子名称: CHLORIDE ION, GENERAL CONTROL PROTEIN GCN4, iodobenzene
著者Yadav, M.K, Redman, J.E, Alvarez-Gutierrez, J.M, Zhang, Y, Stout, C.D, Ghadiri, M.R.
登録日2003-09-15
公開日2004-10-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure-Based Engineering of Internal Cavities in Coiled-Coil Peptides
Biochemistry, 44, 2005
2WO3
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Crystal Structure of the EphA4-ephrinA2 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EPHRIN TYPE-A RECEPTOR, EPHRIN-A2
著者Bowden, T.A, Aricescu, A.R, Nettleship, J.E, Siebold, C, Rahman-Huq, N, Owens, R.J, Stuart, D.I, Jones, E.Y.
登録日2009-07-21
公開日2009-10-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Plasticity of Eph-Receptor A4 Facilitates Cross-Class Ephrin Signalling
Structure, 17, 2009
4GMA
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Crystal structure of the adenosylcobalamin riboswitch
分子名称: Adenosylcobalamin, Adenosylcobalamin riboswitch
著者Reyes, F.E, Johnson, J.E, Polaski, J.T, Batey, R.T.
登録日2012-08-15
公開日2012-10-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.94 Å)
主引用文献B12 cofactors directly stabilize an mRNA regulatory switch.
Nature, 492, 2012
1F2N
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RICE YELLOW MOTTLE VIRUS
分子名称: CALCIUM ION, CAPSID PROTEIN
著者Qu, C, Liljas, L, Opalka, N, Brugidou, C, Yeager, M, Beachy, R.N, Fauquet, C.M, Johnson, J.E, Lin, T.
登録日2000-05-26
公開日2000-11-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献3D domain swapping modulates the stability of members of an icosahedral virus group.
Structure Fold.Des., 8, 2000
1GBK
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ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID
分子名称: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID INHIBITOR, SULFATE ION
著者Mace, J.E, Agard, D.A.
登録日1995-09-06
公開日1996-01-29
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBB
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Alpha-lytic protease with met 190 replaced by ALA AND GLY 216 replaced by ALA complex with METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID
分子名称: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID INHIBITOR, SULFATE ION
著者Mace, J.E, Agard, D.A.
登録日1995-09-06
公開日1996-01-29
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1SKX
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Structural Disorder in the Complex of Human PXR and the Macrolide Antibiotic Rifampicin
分子名称: Orphan nuclear receptor PXR, RIFAMPICIN
著者Chrencik, J.E, Xue, Y, Orans, J.O, Redinbo, M.R.
登録日2004-03-05
公開日2005-03-08
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural disorder in the complex of human pregnane x receptor and the macrolide antibiotic rifampicin
Mol.Endocrinol., 19, 2005
1H2F
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BACILLUS STEAROTHERMOPHILUS PHOE (previously known as yhfr) in complex with trivanadate
分子名称: PHOSPHATASE, PHOSPHATE ION, TRIVANADATE
著者Rigden, D.J, Littlejohn, J.E, Jedrzejas, M.J.
登録日2002-08-08
公開日2002-08-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of Phosphate and Trivanadate Complexes of Bacillus Stearothermophilus Phosphatase Phoe: Structural and Functional Analysis in the Cofactor-Dependent Phosphoglycerate Mutase Superfamily
J.Mol.Biol., 325, 2003
4HPP
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Crystal structure of novel glutamine synthase homolog
分子名称: CALCIUM ION, GLUTAMIC ACID, MAGNESIUM ION, ...
著者Ladner, J.E, Atanasova, V, Dolezelova, Z, Parsons, J.F.
登録日2012-10-24
公開日2012-12-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and Activity of PA5508, a Hexameric Glutamine Synthetase Homologue.
Biochemistry, 51, 2012
1HGD
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BINDING OF INFLUENZA VIRUS HEMAGGLUTININ TO ANALOGS OF ITS CELL-SURFACE RECEPTOR, SIALIC ACID: ANALYSIS BY PROTON NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND X-RAY CRYSTALLOGRAPHY
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, CHAIN HA1, ...
著者Sauter, N.K, Hanson, J.E, Glick, G.D, Brown, J.H, Crowther, R.L, Park, S.-J, Skehel, J.J, Wiley, D.C.
登録日1991-11-01
公開日1994-01-31
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Binding of influenza virus hemagglutinin to analogs of its cell-surface receptor, sialic acid: analysis by proton nuclear magnetic resonance spectroscopy and X-ray crystallography.
Biochemistry, 31, 1992
1UNY
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Structure Based Engineering of Internal Molecular Surfaces Of Four Helix Bundles
分子名称: GENERAL CONTROL PROTEIN GCN4
著者Yadav, M.K, Redman, J.E, Alvarez-Gutierrez, J.M, Zhang, Y, Stout, C.D, Ghadiri, M.R.
登録日2003-09-15
公開日2004-10-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-Based Engineering of Internal Cavities in Coiled-Coil Peptides
Biochemistry, 44, 2005
1BXL
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BU of 1bxl by Molmil
STRUCTURE OF BCL-XL/BAK PEPTIDE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: BAK PEPTIDE, BCL-XL
著者Sattler, M, Liang, H, Nettesheim, D, Meadows, R.P, Harlan, J.E, Eberstadt, M, Yoon, H, Shuker, S.B, Chang, B.S, Minn, A.J, Thompson, C.B, Fesik, S.W.
登録日1996-10-16
公開日1997-10-29
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis.
Science, 275, 1997
2WHJ
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Understanding how diverse mannanases recognise heterogeneous substrates
分子名称: ACETATE ION, BETA-MANNANASE, GLYCEROL, ...
著者Tailford, L.E, Ducros, V.M.A, Flint, J.E, Roberts, S.M, Morland, C, Zechel, D.L, Smith, N, Bjornvad, M.E, Borchert, T.V, Wilson, K.S, Davies, G.J, Gilbert, H.J.
登録日2009-05-05
公開日2009-05-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Understanding How Diverse -Mannanases Recognise Heterogeneous Substrates.
Biochemistry, 48, 2009
1CA8
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Thrombin inhibitors with rigid tripeptidyl aldehydes
分子名称: 2-{(3S)-3-[(benzylsulfonyl)amino]-2-oxopiperidin-1-yl}-N-{(2S)-1-[(3S)-1-carbamimidoylpiperidin-3-yl]-3-oxopropan-2-yl}acetamide, HIRUGEN, SODIUM ION, ...
著者Krishnan, R, Zhang, E, Hakansson, K, Arni, R.K, Tulinsky, A, Lim-Wilby, M.S.L, Levy, O.E, Semple, J.E, Brunck, T.K.
登録日1998-04-27
公開日1999-04-27
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Highly selective mechanism-based thrombin inhibitors: structures of thrombin and trypsin inhibited with rigid peptidyl aldehydes
Biochemistry, 37, 1998
2WM8
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Crystal structure of human magnesium-dependent phosphatase 1 of the haloacid dehalogenase superfamily (MGC5987)
分子名称: 1,2-ETHANEDIOL, MAGNESIUM-DEPENDENT PHOSPHATASE 1
著者Yue, W.W, Shafqat, N, Pike, A.C.W, Chaikuad, A, Bray, J.E, Pilka, E.W, Burgess-Brown, N, Hapka, E, Filippakopoulos, P, von Delft, F, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U.
登録日2009-06-30
公開日2009-07-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structure of Human Magnesium-Dependent Phosphatase 1 of the Haloacid Dehalogenase Superfamily (Mgc5987)
To be Published
4HFW
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Anti Rotavirus Antibody
分子名称: 6-26 Fab Heavy chain, 6-26 Fab Light chain, SULFATE ION
著者Spiller, B.W, Aiyegbo, M, Crowe, J.E.
登録日2012-10-05
公開日2013-05-29
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Human Rotavirus VP6-Specific Antibodies Mediate Intracellular Neutralization by Binding to a Quaternary Structure in the Transcriptional Pore.
Plos One, 8, 2013
4GS1
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Crystal structure of DyP-type peroxidase from Thermobifida cellulosilytica
分子名称: DyP-type peroxidase, GLYCEROL, OXYGEN MOLECULE, ...
著者Lukk, T, Hetta, A.M.A, Jones, A, Solbiati, J, Majumdar, S, Cronan, J.E, Gerlt, J.A, Nair, S.K.
登録日2012-08-27
公開日2013-09-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献DyP-type peroxidases from Stretptomyces and Thermobifida can modify organosolv lignin.
To be Published
4HAP
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Crystal Structure of a GH7 family cellobiohydrolase from Limnoria quadripunctata in complex with cellobiose
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, GH7 family protein, ...
著者Martin, R.N.A, McGeehan, J.E, Streeter, S.D, Cragg, S.M, Guille, M.J, Schnorr, K.M, Kern, M, Bruce, N.C, McQueen-Mason, S.J.
登録日2012-09-27
公開日2013-06-12
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural characterization of a unique marine animal family 7 cellobiohydrolase suggests a mechanism of cellulase salt tolerance
Proc.Natl.Acad.Sci.USA, 110, 2013
1H08
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CDK2 in complex with a disubstituted 2, 4-bis anilino pyrimidine CDK4 inhibitor
分子名称: (2R)-1-{4-[(4-ANILINO-5-BROMOPYRIMIDIN-2-YL)AMINO]PHENOXY}-3-(DIMETHYLAMINO)PROPAN-2-OL, (2S)-1-{4-[(4-ANILINO-5-BROMOPYRIMIDIN-2-YL)AMINO]PHENOXY}-3-(DIMETHYLAMINO)PROPAN-2-OL, CELL DIVISION PROTEIN KINASE 2, ...
著者Breault, G.A, Ellston, R.P.A, Green, S, James, S.R, Jewsbury, P.J, Midgley, C.J, Minshull, C.A, Pauptit, R.A, Tucker, J.A, Pease, J.E.
登録日2002-06-11
公開日2003-07-11
最終更新日2011-10-12
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Cyclin-Dependent Kinase 4 Inhibitors as a Treatment for Cancer. Part 1: Identification and Optimisation of Substituted 4,6-Bis Anilino Pyrimidines
Bioorg.Med.Chem.Lett., 13, 2003
1HGI
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BINDING OF INFLUENZA VIRUS HEMAGGLUTININ TO ANALOGS OF ITS CELL-SURFACE RECEPTOR, SIALIC ACID: ANALYSIS BY PROTON NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND X-RAY CRYSTALLOGRAPHY
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, CHAIN HA1, ...
著者Sauter, N.K, Hanson, J.E, Glick, G.D, Brown, J.H, Crowther, R.L, Park, S.-J, Skehel, J.J, Wiley, D.C.
登録日1991-11-01
公開日1994-01-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Binding of influenza virus hemagglutinin to analogs of its cell-surface receptor, sialic acid: analysis by proton nuclear magnetic resonance spectroscopy and X-ray crystallography.
Biochemistry, 31, 1992
1CEY
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BU of 1cey by Molmil
ASSIGNMENTS, SECONDARY STRUCTURE, GLOBAL FOLD, AND DYNAMICS OF CHEMOTAXIS Y PROTEIN USING THREE-AND FOUR-DIMENSIONAL HETERONUCLEAR (13C,15N) NMR SPECTROSCOPY
分子名称: CHEY
著者Moy, F.J, Lowry, D.F, Matsumura, P, Dahlquist, F.W, Krywko, J.E, Domaille, P.J.
登録日1994-11-23
公開日1995-02-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Assignments, secondary structure, global fold, and dynamics of chemotaxis Y protein using three- and four-dimensional heteronuclear (13C,15N) NMR spectroscopy.
Biochemistry, 33, 1994
1UNX
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Structure Based Engineering of Internal Molecular Surfaces Of Four Helix Bundles
分子名称: GENERAL CONTROL PROTEIN GCN4
著者Yadav, M.K, Redman, J.E, Alvarez-Gutierrez, J.M, Zhang, Y, Stout, C.D, Ghadiri, M.R.
登録日2003-09-15
公開日2004-10-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-Based Engineering of Internal Cavities in Coiled-Coil Peptides
Biochemistry, 44, 2005
4GRB
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Casein kinase 2 (CK2) bound to inhibitor
分子名称: 5-(2-{[4-(dimethylcarbamoyl)phenyl]amino}-4-methoxypyrimidin-5-yl)thiophene-3-carboxylic acid, CHLORIDE ION, Casein kinase II subunit alpha
著者Larsen, N.A, Dowling, J.E, Ferguson, A.D.
登録日2012-08-24
公開日2013-08-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure and Property Based Design of Pyrazolo[1,5-a]pyrimidine Inhibitors of CK2 Kinase with Activity in Vivo.
ACS Med Chem Lett, 4, 2013
1UO1
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Structure Based Engineering of Internal Molecular Surfaces Of Four Helix Bundles
分子名称: GENERAL CONTROL PROTEIN GCN4
著者Yadav, M.K, Redman, J.E, Alvarez-Gutierrez, J.M, Zhang, Y, Stout, C.D, Ghadiri, M.R.
登録日2003-09-15
公開日2004-10-13
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-Based Engineering of Internal Cavities in Coiled-Coil Peptides
Biochemistry, 44, 2005
1UO2
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Structure Based Engineering of Internal Molecular Surfaces Of Four Helix Bundles
分子名称: GENERAL CONTROL PROTEIN GCN4
著者Yadav, M.K, Redman, J.E, Alvarez-Gutierrez, J.M, Zhang, Y, Stout, C.D, Ghadiri, M.R.
登録日2003-09-15
公開日2004-10-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structure-Based Engineering of Internal Cavities in Coiled-Coil Peptides
Biochemistry, 44, 2005

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