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PDB: 6626 件

4ZVS
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Caspase-7 Variant 1 (V1) with reprogrammed substrate specificity due to Y230A/W232M/S234N substitutions, bound to DEVD inhibitor.
分子名称: Caspase-7, DEVD inhibitor
著者MacPherson, D.J, Hill, M.E, Hardy, J.A.
登録日2015-05-18
公開日2016-04-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition.
Acs Chem.Biol., 11, 2016
4ZVO
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Caspase-7 Variant 4 (V4) with reprogrammed substrate specificity due to Y230V/W232Y/S234V/Q276D substitutions bound to VEID inhibitor.
分子名称: Caspase-7, Peptide ACE-VAL-GLU-ILE-ASJ
著者Hill, M.E, MacPherson, D.J, Hardy, J.A.
登録日2015-05-18
公開日2016-04-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition.
Acs Chem.Biol., 11, 2016
6RA7
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Human tnik in complex with compound 9
分子名称: 1,2-ETHANEDIOL, 2-[8-azanyl-2-(2-fluoranylpyridin-4-yl)-1,7-naphthyridin-5-yl]propan-2-ol, MAGNESIUM ION, ...
著者Read, J.A.
登録日2019-04-05
公開日2019-11-06
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Tool inhibitors and assays to interrogate the biology of the TRAF2 and NCK interacting kinase
To Be Published
6RA5
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Human tnik in complex with compound 9
分子名称: 5-bromanyl-2-(2-fluoranylpyridin-4-yl)-1,7-naphthyridin-8-amine, MAGNESIUM ION, TRAF2 and NCK-interacting protein kinase
著者Read, J.A.
登録日2019-04-05
公開日2020-05-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Tool inhibitors and assays to interrogate the biology of the TRAF2 and NCK interacting kinase
To Be Published
6R5R
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BU of 6r5r by Molmil
The crystal structure of Glycoside Hydrolase BglX inactive mutant D286N from P. aeruginosa in complex with cellobiose
分子名称: DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, Periplasmic beta-glucosidase, ...
著者Batuecas, M.T, Hermoso, J.A.
登録日2019-03-25
公開日2020-04-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Catalytic Cycle of Glycoside Hydrolase BglX fromPseudomonas aeruginosaand Its Implications for Biofilm Formation.
Acs Chem.Biol., 15, 2020
6RBJ
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Crystal structure of KDM3B in complex with 5-(1H-tetrazol-5-yl)quinolin-8-ol
分子名称: 1,2-ETHANEDIOL, 5-(1~{H}-1,2,3,4-tetrazol-5-yl)quinolin-8-ol, CHLORIDE ION, ...
著者Johansson, C, Newman, J.A, Kawamura, A, Schofield, C.J, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U.C.T.
登録日2019-04-10
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.093 Å)
主引用文献Crystal structure of KDM3B in complex with 5-(1H-tetrazol-5-yl)quinolin-8-ol
To Be Published
4ZVU
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Caspase-7 wild-type bound to the caspase-6 cognate tetrapeptide inhibitor Ac-VEID-cho
分子名称: Caspase-7, Tetrapeptide Inhibitor Ac-VEID-CHO
著者Hardy, J.A, MacPherson, D.J, Hill, M.E.
登録日2015-05-18
公開日2016-04-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition.
Acs Chem.Biol., 11, 2016
4ZVQ
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BU of 4zvq by Molmil
Caspase-7 Variant 2 (V2) with reprogrammed substrate specificity due to Y230V/W232M/Q276C substitutions bound to VEID inhibitor.
分子名称: Caspase-7, Peptide ACE-VAL-GLU-ILE-ASA
著者Hill, M.E, MacPherson, D.J, Hardy, J.A.
登録日2015-05-18
公開日2016-04-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition.
Acs Chem.Biol., 11, 2016
6RFK
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BU of 6rfk by Molmil
Crystal structure of EGRCK-inhibited Gla-domainless fIXa (K148Q, R150Q variant)
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Coagulation factor IX, ...
著者Huntington, J.A, Sendall, T.J.
登録日2019-04-15
公開日2019-06-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献NMR resonance assignments of apo and EGRCK-inhibited factor IXa
To Be Published
6S4S
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BU of 6s4s by Molmil
CBDP35 Native structure
分子名称: MALONATE ION, PlyP35
著者Hermoso, J.A, Bartual, S.G.
登録日2019-06-28
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献CBDP35 Native structure
To Be Published
7E6V
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The crystal structure of foot-and-mouth disease virus(FMDV) 2C protein 97-318aa
分子名称: ACETATE ION, Protein 2C
著者Zhang, C, Wojdyla, J.A, Qin, B, Wang, M, Gao, X, Cui, S.
登録日2021-02-24
公開日2022-06-29
最終更新日2022-07-20
実験手法X-RAY DIFFRACTION (1.832 Å)
主引用文献An anti-picornaviral strategy based on the crystal structure of foot-and-mouth disease virus 2C protein.
Cell Rep, 40, 2022
7JKC
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BU of 7jkc by Molmil
Sheep Connexin-46 at 1.9 angstroms resolution by CryoEM
分子名称: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-3 protein
著者Flores, J.A, Haddad, B.G, Dolan, K.D, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L.
登録日2020-07-28
公開日2020-09-09
実験手法ELECTRON MICROSCOPY (1.9 Å)
主引用文献Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom.
Nat Commun, 11, 2020
7JNH
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Crystal structure of a double-ENE RNA stability element in complex with a 28-mer poly(A) RNA
分子名称: 28-mer poly(A) RNA, COBALT HEXAMMINE(III), Core double ENE RNA (Xtal construct) from Oryza sativa transposon,Core double ENE RNA (Xtal construct) from Oryza sativa transposon, ...
著者Torabi, S.F, Vaidya, A.T, Tycowski, K.T, DeGregorio, S.J, Wang, J, Shu, M.D, Steitz, T.A, Steitz, J.A.
登録日2020-08-04
公開日2021-01-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献RNA stabilization by a poly(A) tail 3'-end binding pocket and other modes of poly(A)-RNA interaction.
Science, 371, 2021
7JOA
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2:1 cGAS-nucleosome complex
分子名称: Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1, ...
著者Boyer, J.A, Spangler, C.J, Strauss, J.D, Cesmat, A.P, Liu, P, McGinty, R.K, Zhang, Q.
登録日2020-08-06
公開日2020-09-16
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of nucleosome-dependent cGAS inhibition.
Science, 370, 2020
7K2V
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PIKfyve/Fig4/Vac14 complex centered on PIKfyve - map2
分子名称: 1-phosphatidylinositol 3-phosphate 5-kinase
著者Lees, J.A, Reinisch, K.M, Li, P.
登録日2020-09-09
公開日2020-10-21
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (6.6 Å)
主引用文献Insights into Lysosomal PI(3,5)P 2 Homeostasis from a Structural-Biochemical Analysis of the PIKfyve Lipid Kinase Complex.
Mol.Cell, 80, 2020
1WB4
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S954A mutant of the feruloyl esterase module from clostridium thermocellum complexed with sinapinate
分子名称: ACETIC ACID, CADMIUM ION, ENDO-1,4-BETA-XYLANASE Y, ...
著者Tarbouriech, N, Prates, J.A, Fontes, C, Davies, G.J.
登録日2004-10-30
公開日2005-02-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Molecular Determinants of Substrate Specificity in the Feruloyl Esterase Module of Xylanase 10B from Clostridium Thermocellum
Acta Crystallogr.,Sect.D, 61, 2005
1W3G
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Hemolytic lectin from the mushroom Laetiporus sulphureus complexed with two N-acetyllactosamine molecules.
分子名称: GLYCEROL, HEMOLYTIC LECTIN FROM LAETIPORUS SULPHUREUS, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose
著者Mancheno, J.M, Tateno, H, Goldstein, I.J, Martinez-Ripoll, M, Hermoso, J.A.
登録日2004-07-15
公開日2005-02-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Structural Analysis of the Laetiporus Sulphureus Hemolytic Pore-Forming Lectin in Complex with Sugars
J.Biol.Chem., 280, 2005
1VZS
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Solution structure of subunit F6 from the peripheral stalk region of ATP synthase from bovine heart mitochondria
分子名称: ATP SYNTHASE COUPLING FACTOR 6, MITOCHONDRIAL PRECURSOR
著者Carbajo, R.J, Silvester, J.A, Runswick, M.J, Walker, J.E, Neuhaus, D.
登録日2004-05-25
公開日2004-09-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structure of Subunit F(6) from the Peripheral Stalk Region of ATP Synthase from Bovine Heart Mitochondria
J.Mol.Biol., 342, 2004
1WB6
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S954A mutant of the feruloyl esterase module from clostridium thermocellum complexed with vanillate
分子名称: ACETATE ION, CADMIUM ION, ENDO-1,4-BETA-XYLANASE Y, ...
著者Tarbouriech, N, Prates, J.A, Fontes, C, Davies, G.J.
登録日2004-10-30
公開日2006-05-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Molecular Determinants of Substrate Specificity in the Feruloyl Esterase Module of Xylanase 10B from Clostridium Thermocellum
Acta Crystallogr.,Sect.D, 61, 2005
1VYK
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CRYSTAL STRUCTURE OF PSBQ PROTEIN OF PHOTOSYSTEM II FROM HIGHER PLANTS
分子名称: ACETATE ION, OXYGEN-EVOLVING ENHANCER PROTEIN 3, ZINC ION
著者Hermoso, J.A, Balsera, M, De Las Rivas, J, Arellano, J.B.
登録日2004-04-30
公開日2005-05-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献The 1.49 A Resolution Crystal Structure of Psbq from Photosystem II of Spinacia Oleracea Reveals a Ppii Structure in the N-Terminal Region.
J.Mol.Biol., 350, 2005
1W35
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FERREDOXIN-NADP+ REDUCTASE (MUTATION: Y 303 W)
分子名称: FERREDOXIN-NADP+ REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION
著者Hermoso, J.A, Perez-Dorado, I, Medina, M, Julvez, M.M, Sanz-Aparicio, J, Gomez-Moreno, C.
登録日2004-07-13
公開日2005-07-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献C-Terminal Tyrosine of Ferredoxin-Nadp(+) Reductase in Hydride Transfer Processes with Nad(P)(+)/H.
Biochemistry, 44, 2005
1W34
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FERREDOXIN-NADP REDUCTASE (MUTATION: Y 303 S)
分子名称: FERREDOXIN-NADP REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION
著者Hermoso, J.A, Perez-Dorado, I, Medina, M, Julvez, M.M, Sanz-Aparicio, J, Gomez-Moreno, C.
登録日2004-07-13
公開日2005-10-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献C-Terminal Tyrosine of Ferredoxin-Nadp(+) Reductase in Hydride Transfer Processes with Nad(P)(+)/H.
Biochemistry, 44, 2005
1W52
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Crystal structure of a proteolyzed form of pancreatic lipase related protein 2 from horse
分子名称: CALCIUM ION, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, PANCREATIC LIPASE RELATED PROTEIN 2
著者Mancheno, J.M, Jayne, S, Kerfelec, B, Chapus, C, Crenon, I, Hermoso, J.A.
登録日2004-08-04
公開日2006-07-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Crystalization of a Proteolyzed Form of the Horse Pancreatic Lipase-Related Protein 2: Structural Basis for the Specific Detergent Requirement.
Acta Crystallogr.,Sect.D, 60, 2004
1WB5
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S954A mutant of the feruloyl esterase module from clostridium thermocellum complexed with syringate
分子名称: ACETATE ION, CADMIUM ION, ENDO-1,4-BETA-XYLANASE Y, ...
著者Tarbouriech, N, Prates, J.A, Fontes, C, Davies, G.J.
登録日2004-10-30
公開日2005-02-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Molecular Determinants of Substrate Specificity in the Feruloyl Esterase Module of Xylanase 10B from Clostridium Thermocellum
Acta Crystallogr.,Sect.D, 61, 2005
1W8A
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Third LRR domain of Drosophila Slit
分子名称: SLIT PROTEIN
著者Howitt, J.A, Clout, N.J, Hohenester, E.
登録日2004-09-17
公開日2004-10-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Binding Site for Robo Receptors Revealed by Dissection of the Leucine-Rich Repeat Region of Slit.
Embo J., 23, 2004

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件を2024-07-17に公開中

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