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PDB: 6651 件

7JX2
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Cellular retinol-binding protein 2 (CRBP2) in complex with 2-palmitoylglycerol
分子名称: 1,3-dihydroxypropan-2-yl hexadecanoate, Retinol-binding protein 2
著者Silvaroli, J.A, Banarjee, S, Golczak, M.
登録日2020-08-26
公開日2021-03-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular basis for the interaction of cellular retinol binding protein 2 (CRBP2) with nonretinoid ligands.
J.Lipid Res., 62, 2021
7JVG
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Cellular retinol-binding protein 2 (CRBP2) in complex with 1-arachidonoylglycerol
分子名称: (2S)-2,3-dihydroxypropyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, Retinol-binding protein 2
著者Silvaroli, J.A, Golczak, M.
登録日2020-08-21
公開日2021-03-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Molecular basis for the interaction of cellular retinol binding protein 2 (CRBP2) with nonretinoid ligands.
J.Lipid Res., 62, 2021
7JVY
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Cellular retinol-binding protein 2 (CRBP2) in complex with 2-arachidonylglyceryl ether
分子名称: 2-{[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraen-1-yl]oxy}propane-1,3-diol, Retinol-binding protein 2
著者Silvaroli, J.A, Banarjee, S, Golczak, M.
登録日2020-08-24
公開日2021-03-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Molecular basis for the interaction of cellular retinol binding protein 2 (CRBP2) with nonretinoid ligands.
J.Lipid Res., 62, 2021
5ZO1
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Crystal structure of mouse nectin-like molecule 4 (mNecl-4) full ectodomain (Ig1-Ig3), 2.2A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Cell adhesion molecule 4, GLYCEROL
著者Liu, X, An, T, Li, D, Fan, Z, Xiang, P, Li, C, Ju, W, Li, J, Hu, G, Qin, B, Yin, B, Wojdyla, J.A, Wang, M, Yuan, J, Qiang, B, Shu, P, Cui, S, Peng, X.
登録日2018-04-12
公開日2019-01-30
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Structure of the heterophilic interaction between the nectin-like 4 and nectin-like 1 molecules.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
5W1H
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Crystal structure of LbaCas13a (C2c2) bound to mature crRNA (24-nt spacer)
分子名称: GLYCEROL, IODIDE ION, LbaCas13a (C2c2), ...
著者Knott, G.J, Doudna, J.A.
登録日2017-06-03
公開日2017-09-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Guide-bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme.
Nat. Struct. Mol. Biol., 24, 2017
4CGN
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Leishmania major N-myristoyltransferase in complex with a piperidinylindole inhibitor
分子名称: 2-(4-fluorophenyl)-N-(3-piperidin-4-yl-1H-indol-5-yl)ethanamide, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, MAGNESIUM ION, ...
著者Brannigan, J.A, Roberts, S.M, Bell, A.S, Hutton, J.A, Smith, D.F, Tate, E.W, Leatherbarrow, R.J, Wilkinson, A.J.
登録日2013-11-25
公開日2014-07-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Diverse Modes of Binding in Structures of Leishmania Major N-Myristoyltransferase with Selective Inhibitors
Iucrj, 1, 2014
5VTD
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Crystal Structure of the Co-bound Human Heavy-Chain Ferritin variant 122H-delta C-star
分子名称: CALCIUM ION, CHLORIDE ION, COBALT (II) ION, ...
著者Bailey, J.B, Zhang, L, Chiong, J.A, Tezcan, F.A.
登録日2017-05-16
公開日2017-06-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Synthetic Modularity of Protein-Metal-Organic Frameworks.
J. Am. Chem. Soc., 139, 2017
5W3V
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Crystal Structure of macaque APOBEC3H in complex with RNA
分子名称: Apobec3H, RNA (5'-R(P*AP*AP*CP*CP*CP*CP*GP*GP*GP*C)-3'), RNA (5'-R(P*AP*AP*CP*CP*CP*GP*GP*GP*GP*A)-3'), ...
著者Bohn, J.A, Thummar, K, York, A, Raymond, A, Brown, W.C, Bieniasz, P.D, Hatziioannou, T, Smith, J.L.
登録日2017-06-08
公開日2017-10-25
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.243 Å)
主引用文献APOBEC3H structure reveals an unusual mechanism of interaction with duplex RNA.
Nat Commun, 8, 2017
5VJA
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Crystal Structure of human zipper-interacting protein kinase (ZIPK, alias DAPK3) in complex with a pyrazolo[3,4-d]pyrimidinone ligand (HS38)
分子名称: (2R)-2-{[1-(3-chlorophenyl)-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl]sulfanyl}propanamide, DIMETHYL SULFOXIDE, Death-associated protein kinase 3, ...
著者Carlson, D.A, Singer, M.R, Sutherland, C, Redondo, C, Alexander, L, Hughes, P.F, Knapp, S, MacDonald, J.A, Haystead, T.A.J.
登録日2017-04-19
公開日2018-08-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Targeting Pim Kinases and DAPK3 to Control Hypertension.
Cell Chem Biol, 25, 2018
5WHJ
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Crystal structure of Fab fragment of anti-FcRn antibody DX-2507
分子名称: DX-2507 Fab heavy chain, DX-2507 Fab light chain
著者Edwards, T.E, Fairman, J.W, Nixon, A.E, Kenniston, J.A.
登録日2017-07-17
公開日2017-09-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody.
J. Biol. Chem., 292, 2017
7JVD
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Fab of 5.6 monoclonal mouse IgG1 co-crystallized with the trisaccharide form of serotype 3 pneumococcal capsular polysaccharide
分子名称: 5.6 Fab heavy chain, 5.6 Fab light chain, beta-D-glucopyranose-(1-3)-beta-D-glucopyranuronic acid-(1-4)-beta-D-glucopyranose
著者Ozdilek, A, Huang, J, Paschall, A.V, Babb, R, Middleton, D.R, Duke, J.A, Pirofski, L, Mousa, J.J, Avci, F.Y.
登録日2020-08-20
公開日2021-06-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A Structural Model for the Ligand Binding of Pneumococcal Serotype 3 Capsular Polysaccharide-Specific Protective Antibodies.
Mbio, 12, 2021
7JT4
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Crystal Structure of BPTF bromodomain labelled with 5-fluoro-tryptophan
分子名称: Nucleosome-remodeling factor subunit BPTF
著者Johnson, J.A, Shi, K, Aihara, H, Pomerantz, W.C.K.
登録日2020-08-17
公開日2021-07-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Selectivity, ligand deconstruction, and cellular activity analysis of a BPTF bromodomain inhibitor
Org.Biomol.Chem., 17, 2019
7JRS
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Crystal structures of artificially designed homomeric RNA nanoarchitectures
分子名称: RNA 3D nanocage
著者Liu, D, Shao, Y, Piccirilli, J.A, Weizmann, Y.
登録日2020-08-12
公開日2021-09-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Structures of artificially designed discrete RNA nanoarchitectures at near-atomic resolution.
Sci Adv, 7, 2021
7JRR
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Crystal structures of artificially designed homomeric RNA nanoarchitectures
分子名称: MAGNESIUM ION, MANGANESE (II) ION, RNA (50-MER)
著者Liu, D, Shao, Y, Piccirilli, J.A, Weizmann, Y.
登録日2020-08-12
公開日2021-09-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Structures of artificially designed discrete RNA nanoarchitectures at near-atomic resolution.
Sci Adv, 7, 2021
7JRT
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Crystal structures of artificially designed homomeric RNA nanoarchitectures
分子名称: RNA nano bracelet
著者Liu, D, Shao, Y, Piccirilli, J.A, Weizmann, Y.
登録日2020-08-12
公開日2021-09-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.07 Å)
主引用文献Structures of artificially designed discrete RNA nanoarchitectures at near-atomic resolution.
Sci Adv, 7, 2021
7K06
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Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3-prime - 5-prime exoribonucleases
分子名称: CYTIDINE-5'-MONOPHOSPHATE, ERI1 exoribonuclease 3, MAGNESIUM ION
著者Thapar, R, Arvai, A.S, Tainer, J.A.
登録日2020-09-03
公開日2021-10-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3'- 5' exoribonucleases
To Be Published
7K07
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Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3-prime - 5-prime exoribonucleases
分子名称: ADENOSINE MONOPHOSPHATE, ERI1 exoribonuclease 3, MANGANESE (II) ION
著者Thapar, R, Arvai, A.S, Tainer, J.A.
登録日2020-09-03
公開日2021-10-06
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3'- 5' exoribonucleases
To Be Published
7K05
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Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3-prime - 5-prime exoribonucleases
分子名称: ADENOSINE MONOPHOSPHATE, ERI1 exoribonuclease 3, GLYCEROL, ...
著者Thapar, R, Andrew, A.S, Tainer, J.A.
登録日2020-09-03
公開日2021-10-06
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3' - 5' exoribonucleases
To Be Published
5XGQ
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Crystal structure of apo form (free-state) Mycobacterium tuberculosis methionyl-tRNA synthetase
分子名称: Methionine-tRNA ligase
著者Wang, W, Wang, M, Wojdyla, J.A, Cui, S.
登録日2017-04-15
公開日2018-07-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.899 Å)
主引用文献Structural characterization of free-state and product-stateMycobacterium tuberculosismethionyl-tRNA synthetase reveals an induced-fit ligand-recognition mechanism
IUCrJ, 5, 2018
2RIY
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B-specific-1,3-galactosyltransferase (GTB)+H-antigen acceptor
分子名称: Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, octyl 2-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-galactopyranoside
著者Evans, S.V, Alfaro, J.A.
登録日2007-10-13
公開日2008-02-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献ABO(H) blood group A and B glycosyltransferases recognize substrate via specific conformational changes.
J.Biol.Chem., 283, 2008
2RJ4
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B-specific alpha-1,3-galactosyltransferase G176R +UDP+ADA
分子名称: Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ...
著者Evans, S.V, Alfaro, J.A.
登録日2007-10-14
公開日2008-02-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献ABO(H) blood group A and B glycosyltransferases recognize substrate via specific conformational changes.
J.Biol.Chem., 283, 2008
2RIX
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B-specific-1,3-galactosyltransferase)(GTB) + UDP
分子名称: GLYCEROL, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, MANGANESE (II) ION, ...
著者Evans, S.V, Alfaro, J.A.
登録日2007-10-13
公開日2008-02-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献ABO(H) blood group A and B glycosyltransferases recognize substrate via specific conformational changes.
J.Biol.Chem., 283, 2008
2RJ9
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B-specific alpha-1,3-galactosyltransferase (GTB) + UDP+ Amino-deoxy-acceptor
分子名称: Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ...
著者Evans, S.V, Alfaro, J.A.
登録日2007-10-14
公開日2008-02-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献ABO(H) blood group A and B glycosyltransferases recognize substrate via specific conformational changes.
J.Biol.Chem., 283, 2008
8FE5
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Structure of J-PKAc chimera complexed with Aplithianine B
分子名称: 6-[(6P)-6-(1-methyl-1H-imidazol-5-yl)-2,3-dihydro-4H-1,4-thiazin-4-yl]-7,9-dihydro-8H-purin-8-one, DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha
著者Du, L, Wilson, B.A.P, Li, N, Martinez Fiesco, J.A, Dalilian, M, Wang, D, Smith, E.A, Wamiru, A, Goncharova, E.I, Zhang, P, O'Keefe, B.R.
登録日2022-12-05
公開日2023-10-18
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases.
J.Nat.Prod., 86, 2023
7RAH
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Adenylate cyclase toxin RTX domain fragment bound to M1H5 Fab and M2B10 Fab
分子名称: Bifunctional adenylate cyclase toxin/hemolysin CyaA,Bifunctional adenylate cyclase toxin/hemolysin CyaA, CALCIUM ION, M1H5 Fab Heavy Chain, ...
著者Goldsmith, J.A, McLellan, J.S.
登録日2021-07-01
公開日2021-09-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for antibody binding to adenylate cyclase toxin reveals RTX linkers as neutralization-sensitive epitopes.
Plos Pathog., 17, 2021

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