1IAT
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![BU of 1iat by Molmil](/molmil-images/mine/1iat) | CRYSTAL STRUCTURE OF HUMAN PHOSPHOGLUCOSE ISOMERASE/NEUROLEUKIN/AUTOCRINE MOTILITY FACTOR/MATURATION FACTOR | 分子名称: | BETA-MERCAPTOETHANOL, PHOSPHOGLUCOSE ISOMERASE, SULFATE ION | 著者 | Read, J.A, Pearce, J, Li, X, Muirhead, H, Chirgwin, J, Davies, C. | 登録日 | 2001-03-23 | 公開日 | 2001-05-30 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | The crystal structure of human phosphoglucose isomerase at 1.6 A resolution: implications for catalytic mechanism, cytokine activity and haemolytic anaemia. J.Mol.Biol., 309, 2001
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4QTG
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![BU of 4qtg by Molmil](/molmil-images/mine/4qtg) | CRYSTAL STRUCTURE of 5-CARBOXYVANILLATE DECARBOXYLASE LIGW2 (TARGET EFI-505250) FROM NOVOSPHINGOBIUM AROMATICIVORANS DSM 12444 COMPLEXED WITH MANGANESE | 分子名称: | 5-CARBOXYVANILLATE DECARBOXYLASE, GLYCEROL, MANGANESE (II) ION | 著者 | Patskovsky, Y, Vladimirova, A, Toro, R, Bhosle, R, Gerlt, J.A, Raushel, F.M, Almo, S.C. | 登録日 | 2014-07-07 | 公開日 | 2014-08-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Crystal Structure of 5-Carboxyvanillate Decarboxylase LIGW2 from Novosphingobium Aromaticivorans To be Published
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4QS6
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![BU of 4qs6 by Molmil](/molmil-images/mine/4qs6) | CRYSTAL STRUCTURE of 5-CARBOXYVANILLATE DECARBOXYLASE LIGW2 FROM NOVOSPHINGOBIUM AROMATICIVORANS DSM 12444 (TARGET EFI-505250) WITH BOUND 4-HYDROXY-3-METHOXY-5-NITROBENZOIC ACID, NO METAL, THE D314N MUTANT | 分子名称: | 4-hydroxy-3-methoxy-5-nitrobenzoic acid, CHLORIDE ION, GLYCEROL, ... | 著者 | Patskovsky, Y, Vladimirova, A, Toro, R, Bhosle, R, Gerlt, J.A, Raushel, F.M, Almo, S.C. | 登録日 | 2014-07-03 | 公開日 | 2014-08-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Crystal Structure of Ligw2 Decarboxylase from Novosphingobium Aromaticivorans To be Published
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4QRN
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![BU of 4qrn by Molmil](/molmil-images/mine/4qrn) | HIGH-RESOLUTION CRYSTAL STRUCTURE of 5-CARBOXYVANILLATE DECARBOXYLASE (TARGET EFI-505250) FROM NOVOSPHINGOBIUM AROMATICIVORANS DSM 12444 COMPLEXED WITH MANGANESE AND 4-HYDROXY-3-METHOXY-5-NITROBENZOIC ACID | 分子名称: | 4-hydroxy-3-methoxy-5-nitrobenzoic acid, 5-Carboxyvanillate Decarboxylase, ACETATE ION, ... | 著者 | Patskovsky, Y, Vladimirova, A, Toro, R, Bhosle, R, Gerlt, J.A, Raushel, F.M, Almo, S.C. | 登録日 | 2014-07-01 | 公開日 | 2014-08-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | 主引用文献 | Crystal Structure of 5-Carboxyvanillate Decarboxylase from Novosphingobium Aromaticivorans To be Published
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4HH4
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![BU of 4hh4 by Molmil](/molmil-images/mine/4hh4) | Structure of the CcbJ Methyltransferase from Streptomyces caelestis | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CcbJ, GLYCEROL, ... | 著者 | Bauer, J.A, Ondrovicova, G, Kutejova, E, Janata, J. | 登録日 | 2012-10-09 | 公開日 | 2013-10-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure and possible mechanism of the CcbJ methyltransferase from Streptomyces caelestis. Acta Crystallogr.,Sect.D, 70, 2014
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4H1G
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![BU of 4h1g by Molmil](/molmil-images/mine/4h1g) | Structure of Candida albicans Kar3 motor domain fused to maltose-binding protein | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Allingham, J.A, Duan, D, Delorme, C, Joshi, M. | 登録日 | 2012-09-10 | 公開日 | 2012-10-10 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal structure of the Candida albicans Kar3 kinesin motor domain fused to maltose-binding protein. Biochem.Biophys.Res.Commun., 428, 2012
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4FP4
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![BU of 4fp4 by Molmil](/molmil-images/mine/4fp4) | Crystal structure of isoprenoid synthase a3mx09 (target efi-501993) from pyrobaculum calidifontis | 分子名称: | GERAN-8-YL GERAN, Polyprenyl synthetase, UNKNOWN ATOM OR ION, ... | 著者 | Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Poulter, C.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2012-06-21 | 公開日 | 2012-07-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily. Proc.Natl.Acad.Sci.USA, 110, 2013
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4F62
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![BU of 4f62 by Molmil](/molmil-images/mine/4f62) | Crystal structure of a putative farnesyl-diphosphate synthase from Marinomonas sp. MED121 (Target EFI-501980) | 分子名称: | CHLORIDE ION, GLYCEROL, Geranyltranstransferase, ... | 著者 | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Poulter, C.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2012-05-14 | 公開日 | 2012-06-13 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | 主引用文献 | Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily. Proc.Natl.Acad.Sci.USA, 110, 2013
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4HGY
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![BU of 4hgy by Molmil](/molmil-images/mine/4hgy) | Structure of the CcbJ Methyltransferase from Streptomyces caelestis | 分子名称: | 1,2-ETHANEDIOL, CcbJ, SULFATE ION | 著者 | Bauer, J.A, Ondrovicova, G, Kutejova, E, Janata, J. | 登録日 | 2012-10-09 | 公開日 | 2013-10-30 | 最終更新日 | 2014-04-16 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure and possible mechanism of the CcbJ methyltransferase from Streptomyces caelestis. Acta Crystallogr.,Sect.D, 70, 2014
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4HGZ
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![BU of 4hgz by Molmil](/molmil-images/mine/4hgz) | Structure of the CcbJ Methyltransferase from Streptomyces caelestis | 分子名称: | 1,2-ETHANEDIOL, CcbJ, LITHIUM ION, ... | 著者 | Bauer, J.A, Ondrovicova, G, Kutejova, E, Janata, J. | 登録日 | 2012-10-09 | 公開日 | 2013-10-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure and possible mechanism of the CcbJ methyltransferase from Streptomyces caelestis. Acta Crystallogr.,Sect.D, 70, 2014
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4JIY
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![BU of 4jiy by Molmil](/molmil-images/mine/4jiy) | RNA three-way junction stabilized by a supramolecular di-iron(II) cylinder drug | 分子名称: | 5'-(CGUACG)-3', FE (II) ION, N-[(1E)-PYRIDIN-2-YLMETHYLENE]-N-[4-(4-{[(1E)-PYRIDIN-2-YLMETHYLENE]AMINO}BENZYL)PHENYL]AMINE | 著者 | Sigel, R.K.O, Schnabl, J.A, Freisinger, E, Spingler, B, Hannon, M.J. | 登録日 | 2013-03-07 | 公開日 | 2013-09-04 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Binding of a designed anti-cancer drug to the central cavity of an RNA three-way junction. Angew.Chem.Int.Ed.Engl., 52, 2013
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5QTD
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![BU of 5qtd by Molmil](/molmil-images/mine/5qtd) | Unliganded T. brucei FPPS | 分子名称: | Farnesyl pyrophosphate synthase, GLYCEROL, PHOSPHATE ION, ... | 著者 | Muenzker, L, Petrick, J.K, Schleberger, C, Cornaciu, I, Marquez, J.A, Jahnke, W. | 登録日 | 2019-08-09 | 公開日 | 2020-10-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.642 Å) | 主引用文献 | Unliganded T. brucei FPPS To Be Published
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5O26
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![BU of 5o26 by Molmil](/molmil-images/mine/5o26) | Crystal structure of WNK3 kinase domain in a diphosphorylated state and in complex with AMP-PNP/Mg2+ | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Pinkas, D.M, Bufton, J.C, Newman, J.A, Kopec, J, Borkowska, O, Chalk, R, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A. | 登録日 | 2017-05-19 | 公開日 | 2017-06-28 | 最終更新日 | 2019-10-16 | 実験手法 | X-RAY DIFFRACTION (2.379 Å) | 主引用文献 | Crystal structure of WNK3 kinase domain in a diphosphorylated state and in complex with AMP-PNP/Mg2+ To Be Published
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5QTK
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![BU of 5qtk by Molmil](/molmil-images/mine/5qtk) | T. brucei FPPS in complex with CID 69539 | 分子名称: | Farnesyl pyrophosphate synthase, N,N-diethyl-4-methylbenzene-1-sulfonamide, PHOSPHATE ION, ... | 著者 | Muenzker, L, Petrick, J.K, Schleberger, C, Cornaciu, I, Marquez, J.A, Jahnke, W. | 登録日 | 2019-08-09 | 公開日 | 2020-10-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.857 Å) | 主引用文献 | T. brucei FPPS in complex with CID 69539 To Be Published
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5QTE
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![BU of 5qte by Molmil](/molmil-images/mine/5qte) | T. brucei FPPS in complex with CID 4563894 | 分子名称: | (4S)-3-(4-chlorobenzene-1-carbonyl)-1,3-thiazolidine-4-carboxylic acid, Farnesyl pyrophosphate synthase, GLYCEROL, ... | 著者 | Muenzker, L, Petrick, J.K, Schleberger, C, Cornaciu, I, Marquez, J.A, Jahnke, W. | 登録日 | 2019-08-09 | 公開日 | 2020-10-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.072 Å) | 主引用文献 | T. brucei FPPS in complex with CID 4563894 To Be Published
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5O2B
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![BU of 5o2b by Molmil](/molmil-images/mine/5o2b) | Crystal structure of WNK3 kinase domain in a diphosphorylated state and in a complex with the inhibitor PP-121 | 分子名称: | 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, SODIUM ION, Serine/threonine-protein kinase WNK3 | 著者 | Pinkas, D.M, Bufton, J.C, Newman, J.A, Borkowska, O, Chalk, R, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC) | 登録日 | 2017-05-19 | 公開日 | 2017-06-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.038 Å) | 主引用文献 | Crystal structure of WNK3 kinase domain in a diphosphorylated state and in a complex with the inhibitor PP-121 To Be Published
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5QTG
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![BU of 5qtg by Molmil](/molmil-images/mine/5qtg) | T. brucei FPPS in complex with CID 126782062 | 分子名称: | 2-fluoro-N,3-dimethylbenzene-1-sulfonamide, Farnesyl pyrophosphate synthase, GLYCEROL, ... | 著者 | Muenzker, L, Petrick, J.K, Schleberger, C, Cornaciu, I, Marquez, J.A, Jahnke, W. | 登録日 | 2019-08-09 | 公開日 | 2020-10-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.093 Å) | 主引用文献 | T. brucei FPPS in complex with CID 126782062 To Be Published
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5QTF
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![BU of 5qtf by Molmil](/molmil-images/mine/5qtf) | T. brucei FPPS in complex with CID 144539 | 分子名称: | 1-(3-chloro-4-fluorophenyl)methanamine, Farnesyl pyrophosphate synthase, GLYCEROL, ... | 著者 | Muenzker, L, Petrick, J.K, Schleberger, C, Cornaciu, I, Marquez, J.A, Jahnke, W. | 登録日 | 2019-08-09 | 公開日 | 2020-10-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.783 Å) | 主引用文献 | T. brucei FPPS in complex with CID 144539 To Be Published
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5QTH
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![BU of 5qth by Molmil](/molmil-images/mine/5qth) | T. brucei FPPS in complex with CID 2799882 | 分子名称: | Farnesyl pyrophosphate synthase, GLYCEROL, N,N-dimethyl-2-(methylsulfanyl)pyridine-3-carboxamide, ... | 著者 | Muenzker, L, Petrick, J.K, Schleberger, C, Cornaciu, I, Marquez, J.A, Jahnke, W. | 登録日 | 2019-08-09 | 公開日 | 2020-10-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.887 Å) | 主引用文献 | T. brucei FPPS in complex with CID 2799882 To Be Published
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5QTI
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![BU of 5qti by Molmil](/molmil-images/mine/5qti) | T. brucei FPPS in complex with CID 62483448 | 分子名称: | 3-(2-bromophenoxy)pyridazine, Farnesyl pyrophosphate synthase, GLYCEROL, ... | 著者 | Muenzker, L, Petrick, J.K, Schleberger, C, Cornaciu, I, Marquez, J.A, Jahnke, W. | 登録日 | 2019-08-09 | 公開日 | 2020-10-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.112 Å) | 主引用文献 | T. brucei FPPS in complex with CID 62483448 To Be Published
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5QTJ
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![BU of 5qtj by Molmil](/molmil-images/mine/5qtj) | T. brucei FPPS in complex with CID 47256035 | 分子名称: | Farnesyl pyrophosphate synthase, GLYCEROL, N-[(2-chloro-6-fluorophenyl)methyl]-N,2-dimethylpyrimidine-4-carboxamide, ... | 著者 | Muenzker, L, Petrick, J.K, Schleberger, C, Cornaciu, I, Marquez, J.A, Jahnke, W. | 登録日 | 2019-08-09 | 公開日 | 2020-10-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | 主引用文献 | T. brucei FPPS in complex with CID 47256035 To Be Published
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5RWB
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![BU of 5rwb by Molmil](/molmil-images/mine/5rwb) | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z2856434899 | 分子名称: | 1-[(thiophen-3-yl)methyl]piperidin-4-ol, DIMETHYL SULFOXIDE, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 | 著者 | Bradshaw, W.J, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | 登録日 | 2020-10-30 | 公開日 | 2020-11-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. Structure, 2024
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5RWL
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![BU of 5rwl by Molmil](/molmil-images/mine/5rwl) | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z1348371854 | 分子名称: | 5-(1,4-oxazepan-4-yl)pyridine-2-carbonitrile, DIMETHYL SULFOXIDE, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 | 著者 | Bradshaw, W.J, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | 登録日 | 2020-10-30 | 公開日 | 2020-11-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. Structure, 2024
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5RWU
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![BU of 5rwu by Molmil](/molmil-images/mine/5rwu) | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z57778470 | 分子名称: | 1-methyl-N-[(2-methylphenyl)methyl]-1H-tetrazol-5-amine, DIMETHYL SULFOXIDE, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 | 著者 | Bradshaw, W.J, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | 登録日 | 2020-10-30 | 公開日 | 2020-11-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. Structure, 2024
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5RX7
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![BU of 5rx7 by Molmil](/molmil-images/mine/5rx7) | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z1545196403 | 分子名称: | 2-fluoro-N-[(1H-pyrazol-3-yl)methyl]aniline, DIMETHYL SULFOXIDE, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 | 著者 | Bradshaw, W.J, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | 登録日 | 2020-10-30 | 公開日 | 2020-11-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. Structure, 2024
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