3NTB
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![BU of 3ntb by Molmil](/molmil-images/mine/3ntb) | Structure of 6-methylthio naproxen analog bound to mCOX-2. | Descriptor: | (2S)-2-[6-(methylsulfanyl)naphthalen-2-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Duggan, K.C, Musee, J, Walters, M.J, Harp, J.M, Kiefer, J.R, Oates, J.A, Marnett, L.J. | Deposit date: | 2010-07-03 | Release date: | 2010-09-01 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Molecular basis for cyclooxygenase inhibition by the non-steroidal anti-inflammatory drug naproxen. J.Biol.Chem., 285, 2010
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1P1M
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![BU of 1p1m by Molmil](/molmil-images/mine/1p1m) | Structure of Thermotoga maritima amidohydrolase TM0936 bound to Ni and methionine | Descriptor: | Hypothetical protein TM0936, METHIONINE, NICKEL (II) ION | Authors: | Kniewel, R, Buglino, J.A, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2003-04-12 | Release date: | 2003-04-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of the hypothetical protein TM0936 from Thermotoga maritima at
1.5A bound to Ni and methionine To be Published, 2003
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3NT1
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![BU of 3nt1 by Molmil](/molmil-images/mine/3nt1) | High resolution structure of naproxen:COX-2 complex. | Descriptor: | (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Duggan, K.C, Musee, J, Walters, M.J, Harp, J.M, Kiefer, J.R, Oates, J.A, Marnett, L.J. | Deposit date: | 2010-07-02 | Release date: | 2010-09-01 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Molecular basis for cyclooxygenase inhibition by the non-steroidal anti-inflammatory drug naproxen. J.Biol.Chem., 285, 2010
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3ZC3
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![BU of 3zc3 by Molmil](/molmil-images/mine/3zc3) | FERREDOXIN-NADP REDUCTASE (MUTATION S80A) COMPLEXED WITH NADP BY COCRYSTALLIZATION | Descriptor: | FERREDOXIN-NADP REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Martinez-Julvez, M, Hurtado-Guerrero, R, Herguedas, B, Sanchez-Azqueta, A, Hervas, M, Navarro, J.A, Medina, M. | Deposit date: | 2012-11-15 | Release date: | 2013-11-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A Hydrogen Bond Network in the Active Site of Anabaena Ferredoxin-Nadp(+) Reductase Modulates its Catalytic Efficiency. Biochim.Biophys.Acta, 1837, 2013
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3ZDJ
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3ZIV
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![BU of 3ziv by Molmil](/molmil-images/mine/3ziv) | |
4BJ4
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![BU of 4bj4 by Molmil](/molmil-images/mine/4bj4) | Structure of Pseudomonas aeruginosa amidase Ampdh2 | Descriptor: | AMPDH2, CITRATE ANION | Authors: | Martinez-Caballero, C.S, Carrasco-Lopez, C, Artola-Recolons, C, Hermoso, J.A. | Deposit date: | 2013-04-16 | Release date: | 2013-07-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.722 Å) | Cite: | Reaction Products and the X-Ray Structure of Ampdh2, a Virulence Determinant of Pseudomonas Aeruginosa. J.Am.Chem.Soc., 135, 2013
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4B12
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![BU of 4b12 by Molmil](/molmil-images/mine/4b12) | Plasmodium vivax N-myristoyltransferase with a bound benzofuran inhibitor (compound 23) | Descriptor: | 1-[3-methyl-4-(piperidin-4-yloxy)-1-benzofuran-2-yl]-3-phenylpropan-1-one, 2-oxopentadecyl-CoA, CHLORIDE ION, ... | Authors: | Yu, Z, Brannigan, J.A, Moss, D.K, Brzozowski, A.M, Wilkinson, A.J, Holder, A.A, Tate, E.W, Leatherbarrow, R.J. | Deposit date: | 2012-07-06 | Release date: | 2012-10-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Design and Synthesis of Inhibitors of Plasmodium Falciparum N-Myristoyltransferase, a Promising Target for Anti-Malarial Drug Discovery. J.Med.Chem., 55, 2012
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6Y0P
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![BU of 6y0p by Molmil](/molmil-images/mine/6y0p) | isopenicillin N synthase in complex with IPN and Fe using FT-SSX methods | Descriptor: | FE (III) ION, ISOPENICILLIN N, Isopenicillin N synthase, ... | Authors: | Rabe, P, Beale, J.H, Lang, P.A, Dirr, A.S, Leissing, T.M, Butryn, A, Aller, P, Kamps, J.J.A.G, Axford, D, McDonough, M.A, Orville, A.M, Owen, R, Schofield, C.J. | Deposit date: | 2020-02-10 | Release date: | 2021-02-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | X-ray free-electron laser studies reveal correlated motion during isopenicillin N synthase catalysis. Sci Adv, 7, 2021
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4BB7
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![BU of 4bb7 by Molmil](/molmil-images/mine/4bb7) | Crystal structure of the yeast Rsc2 BAH domain | Descriptor: | CHLORIDE ION, CHROMATIN STRUCTURE-REMODELING COMPLEX SUBUNIT RSC2, GLYCEROL, ... | Authors: | Chambers, A.L, Pearl, L.H, Oliver, A.W, Downs, J.A. | Deposit date: | 2012-09-20 | Release date: | 2013-08-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Bah Domain of Rsc2 is a Histone H3 Binding Domain. Nucleic Acids Res., 41, 2013
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3NXL
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![BU of 3nxl by Molmil](/molmil-images/mine/3nxl) | Crystal structure of Glucarate dehydratase from Burkholderia cepacia complexed with magnesium | Descriptor: | CARBONATE ION, Glucarate dehydratase, MAGNESIUM ION | Authors: | Fedorov, A.A, Fedorov, E.V, Gerlt, J.A, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2010-07-14 | Release date: | 2010-07-28 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (1.885 Å) | Cite: | Crystal structure of Glucarate dehydratase from Burkholderia cepacia complexed with magnesium To be Published
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1PFE
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![BU of 1pfe by Molmil](/molmil-images/mine/1pfe) | Echinomycin-(gcgtacgc)2 complex | Descriptor: | 2-CARBOXYQUINOXALINE, 5'-D(*GP*CP*GP*TP*AP*CP*GP*C)-3', CHLORIDE ION, ... | Authors: | Cuesta-Seijo, J.A. | Deposit date: | 2003-05-26 | Release date: | 2004-06-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Structures of Complexes between Echinomycin and Duplex DNA. Acta Crystallogr.,Sect.D, 61, 2005
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5KZE
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![BU of 5kze by Molmil](/molmil-images/mine/5kze) | N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus | Descriptor: | GLYCEROL, N-acetylneuraminate lyase, SULFATE ION | Authors: | North, R.A, Watson, A.J.A, Pearce, F.G, Muscroft-Taylor, A.C, Friemann, R, Fairbanks, A.J, Dobson, R.C.J. | Deposit date: | 2016-07-25 | Release date: | 2017-01-11 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structure and inhibition of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus. FEBS Lett., 590, 2016
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3O2A
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![BU of 3o2a by Molmil](/molmil-images/mine/3o2a) | Ligand-binding domain of GluA2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator | Descriptor: | GLUTAMIC ACID, GLYCEROL, Glutamate receptor 2, ... | Authors: | Maclean, J.K.F, Basten, S, Campbell, R.A, Cumming, I.A, Gillen, K.J, Gillespie, J, Jamieson, C, Kazemier, B, Kiczun, M, Lamont, Y, Lyons, A.J, Moir, E.M, Morrow, J.A, Papakosta, M, Rankovic, Z, Smith, L. | Deposit date: | 2010-07-22 | Release date: | 2010-09-15 | Last modified: | 2017-08-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A novel series of positive modulators of the AMPA receptor: discovery and structure based hit-to-lead studies. Bioorg.Med.Chem.Lett., 20, 2010
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4BF5
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1PCS
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![BU of 1pcs by Molmil](/molmil-images/mine/1pcs) | THE 2.15 A CRYSTAL STRUCTURE OF A TRIPLE MUTANT PLASTOCYANIN FROM THE CYANOBACTERIUM SYNECHOCYSTIS SP. PCC 6803 | Descriptor: | COPPER (II) ION, PLASTOCYANIN | Authors: | Romero, A, De La Cerda, B, Varela, P.F, Navarro, J.A, Hervas, M, De La Rosa, M.A. | Deposit date: | 1997-06-17 | Release date: | 1997-12-17 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The 2.15 A crystal structure of a triple mutant plastocyanin from the cyanobacterium Synechocystis sp. PCC 6803. J.Mol.Biol., 275, 1998
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4BA5
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![BU of 4ba5 by Molmil](/molmil-images/mine/4ba5) | Crystal structure of omega-transaminase from Chromobacterium violaceum | Descriptor: | 3-[O-PHOSPHONOPYRIDOXYL]--AMINO-BENZOIC ACID, AMINOTRANSFERASE, SULFATE ION | Authors: | Sayer, C, Isupov, M.N, Littlechild, J.A. | Deposit date: | 2012-09-11 | Release date: | 2013-03-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Structural Studies with Pseudomonas and Chromobacterium [Omega]-Aminotransferases Provide Insights Into Their Differing Substrate Specificity. Acta Crystallogr.,Sect.D, 69, 2013
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1PDU
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![BU of 1pdu by Molmil](/molmil-images/mine/1pdu) | Ligand-binding domain of Drosophila orphan nuclear receptor DHR38 | Descriptor: | nuclear hormone receptor HR38 | Authors: | Baker, K.D, Shewchuk, L.M, Korlova, T, Makishima, M, Hassell, A.M, Wisely, B, Caravella, J.A, Lambert, M.H, Wilson, T.M, Mangelsdorf, D.J. | Deposit date: | 2003-05-20 | Release date: | 2003-06-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Drosophila orphan nuclear receptor DHR38 mediates an atypical ecdysteroid signaling pathway. Cell(Cambridge,Mass.), 113, 2003
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4BL2
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3NQA
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![BU of 3nqa by Molmil](/molmil-images/mine/3nqa) | Crystal structure of the mutant F100A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP | Descriptor: | 6-HYDROXYURIDINE-5'-PHOSPHATE, Orotidine 5'-phosphate decarboxylase | Authors: | Fedorov, A.A, Fedorov, E.V, Wood, B.M, Gerlt, J.A, Almo, S.C. | Deposit date: | 2010-06-29 | Release date: | 2011-05-11 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.395 Å) | Cite: | Crystal structure of the mutant F100A of orotidine 5'-monophosphate
decarboxylase from Methanobacterium thermoautotrophicum complexed with
inhibitor BMP To be Published
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4B2O
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![BU of 4b2o by Molmil](/molmil-images/mine/4b2o) | Crystal structure of Bacillus subtilis YmdB, a global regulator of late adaptive responses. | Descriptor: | FE (II) ION, PHOSPHATE ION, YMDB PHOSPHODIESTERASE | Authors: | Newman, J.A, Diethmaier, C, Kovacs, A.T, Rodrigues, C, Kuipers, O.P, Stulke, J, Lewis, R.J. | Deposit date: | 2012-07-17 | Release date: | 2013-07-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | The Ymdb Phosphodiesterase is a Global Regulator of Late Adaptive Responses in Bacillus Subtilis. J.Bacteriol., 196, 2014
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4BKY
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![BU of 4bky by Molmil](/molmil-images/mine/4bky) | Crystal structure of unphosphorylated Maternal Embryonic Leucine zipper Kinase (MELK) in complex with pyrrolopyrazole inhibitor | Descriptor: | 3'-{[(4-bromo-1-methyl-1H-pyrrol-2-yl)carbonyl]amino}-N-[(1S)-1-phenyl-2-(pyrrolidin-1-yl)ethyl]-1',4'-dihydro-5'H-spiro[cyclopropane-1,6'-pyrrolo[3,4-c]pyrazole]-5'-carboxamide, MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE, UNKNOWN ATOM OR ION | Authors: | Canevari, G, Re Depaolini, S, Cucchi, U, Forte, B, Carpinelli, P, Bertrand, J.A. | Deposit date: | 2013-04-30 | Release date: | 2013-08-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structural Insight Into Maternal Embryonic Leucine Zipper Kinase (Melk) Conformation and Inhibition Towards Structure- Based Drug Design. Biochemistry, 52, 2013
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4BHY
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![BU of 4bhy by Molmil](/molmil-images/mine/4bhy) | Structure of alanine racemase from Aeromonas hydrophila | Descriptor: | ALANINE RACEMASE | Authors: | Otero, L.H, Carrasco-Lopez, C, Bernardo-Garcia, N, Hermoso, J.A. | Deposit date: | 2013-04-09 | Release date: | 2014-01-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Structural Basis for the Broad Specificity of a New Family of Amino-Acid Racemases. Acta Crystallogr.,Sect.D, 70, 2014
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4B98
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![BU of 4b98 by Molmil](/molmil-images/mine/4b98) | The structure of the omega aminotransferase from Pseudomonas aeruginosa | Descriptor: | 3-[O-PHOSPHONOPYRIDOXYL]--AMINO-BENZOIC ACID, BETA-ALANINE--PYRUVATE TRANSAMINASE, CALCIUM ION, ... | Authors: | Sayer, C, Isupov, M.N, Westlake, A, Littlechild, J.A. | Deposit date: | 2012-09-03 | Release date: | 2013-03-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural Studies with Pseudomonas and Chromobacterium [Omega]-Aminotransferases Provide Insights Into Their Differing Substrate Specificity. Acta Crystallogr.,Sect.D, 69, 2013
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4BA7
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![BU of 4ba7 by Molmil](/molmil-images/mine/4ba7) | Crystal Structure of Ancestral Thioredoxin Relative to Last Bacteria Common Ancestor (LBCA) from the Precambrian Period | Descriptor: | 1,2-ETHANEDIOL, LBCA THIOREDOXIN | Authors: | Gavira, J.A, Ingles-Prieto, A, Ibarra-Molero, B, Sanchez-Ruiz, J.M. | Deposit date: | 2012-09-12 | Release date: | 2013-08-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Conservation of Protein Structure Over Four Billion Years Structure, 21, 2013
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