1OGU
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![BU of 1ogu by Molmil](/molmil-images/mine/1ogu) | STRUCTURE OF HUMAN THR160-PHOSPHO CDK2/CYCLIN A COMPLEXED WITH A 2-ARYLAMINO-4-CYCLOHEXYLMETHYL-5-NITROSO-6-AMINOPYRIMIDINE INHIBITOR | 分子名称: | 4-{[4-AMINO-6-(CYCLOHEXYLMETHOXY)-5-NITROSOPYRIMIDIN-2-YL]AMINO}BENZAMIDE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, ... | 著者 | Pratt, D.J, Endicott, J.A, Noble, M.E.M. | 登録日 | 2003-05-13 | 公開日 | 2003-09-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure-Based Design of 2-Arylamino-4-Cyclohexyl Methyl-5-Nitroso-6-Aminopyrimidine Inhibitors of Cyclin-Dependent Kinases 1 and 2 Bioorg.Med.Chem.Lett., 13, 2003
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1OGI
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![BU of 1ogi by Molmil](/molmil-images/mine/1ogi) | FERREDOXIN:NADP+ REDUCTASE MUTANT WITH THR 155 REPLACED BY GLY AND ALA 160 REPLACED BY THR (T155G-A160T) | 分子名称: | FERREDOXIN--NADP+ REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION | 著者 | Hermoso, J.A, Mayoral, T, Julvez, M.M, Medina, M, Sanz-Aparicio, J, Gomez-Moreno, C. | 登録日 | 2003-05-06 | 公開日 | 2003-09-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Involvement of the Pyrophosphate and the 2'-Phosphate Binding Regions of Ferredoxin-Nadp+ Reductase in Coenzyme Specificity. J.Biol.Chem., 278, 2003
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3PDI
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![BU of 3pdi by Molmil](/molmil-images/mine/3pdi) | Precursor bound NifEN | 分子名称: | IRON/SULFUR CLUSTER, L-Cluster (Fe8S9), Nitrogenase MoFe cofactor biosynthesis protein NifE, ... | 著者 | Kaiser, J.T, Hu, Y, Wiig, J.A, Rees, D.C, Ribbe, M.W. | 登録日 | 2010-10-22 | 公開日 | 2011-01-19 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of Precursor-Bound NifEN: A Nitrogenase FeMo Cofactor Maturase/Insertase. Science, 331, 2011
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4AJJ
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![BU of 4ajj by Molmil](/molmil-images/mine/4ajj) | rat LDHA in complex with 2-((3,4-dimethoxyphenyl)methyl))propanedioic acid and N-(2-methyl-1,3-benzothiazol-6-yl)-3-ureido-propanamide | 分子名称: | 2-((3,4-DIMETHOXYPHENYL)METHYL))PROPANEDIOIC ACID, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Tucker, J.A, Brassington, C, Hassall, G, Vogtherr, M, Ward, R, Tart, J, Davies, G, Patel, J, Greenwood, R. | 登録日 | 2012-02-16 | 公開日 | 2012-03-21 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation J.Med.Chem., 55, 2012
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3PBJ
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![BU of 3pbj by Molmil](/molmil-images/mine/3pbj) | Hydrolytic catalysis and structural stabilization in a designed metalloprotein | 分子名称: | CHLORIDE ION, COIL SER L9L-Pen L23H, MERCURY (II) ION, ... | 著者 | Zastrow, M.L, Peacock, A.F.A, Stuckey, J.A, Pecoraro, V.L. | 登録日 | 2010-10-20 | 公開日 | 2011-11-30 | 最終更新日 | 2022-05-04 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Hydrolytic catalysis and structural stabilization in a designed metalloprotein. Nat Chem, 4, 2012
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4AMU
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![BU of 4amu by Molmil](/molmil-images/mine/4amu) | Structure of ornithine carbamoyltransferase from Mycoplasma penetrans with a P321 space group | 分子名称: | ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC | 著者 | Gallego, P, Benach, J, Planell, R, Querol, E, Perez-Pons, J.A, Reverter, D. | 登録日 | 2012-03-13 | 公開日 | 2012-03-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Characterization of the Enzymes Composing the Arginine Deiminase Pathway in Mycoplasma Penetrans. Plos One, 7, 2012
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3PBY
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![BU of 3pby by Molmil](/molmil-images/mine/3pby) | Crystal structure of the mutant L123S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate | 分子名称: | 6-AZA URIDINE 5'-MONOPHOSPHATE, GLYCEROL, Orotidine 5'-monophosphate decarboxylase | 著者 | Fedorov, A.A, Fedorov, E.V, Iiams, V, Wood, B.M, Gerlt, J.A, Almo, S.C. | 登録日 | 2010-10-21 | 公開日 | 2011-09-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site. Biochemistry, 50, 2011
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6ZWV
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![BU of 6zwv by Molmil](/molmil-images/mine/6zwv) | Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: 3 Closed RBDs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Ke, Z, Qu, K, Nakane, T, Xiong, X, Cortese, M, Zila, V, Scheres, S.H.W, Briggs, J.A.G. | 登録日 | 2020-07-28 | 公開日 | 2020-08-05 | 最終更新日 | 2020-12-30 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structures and distributions of SARS-CoV-2 spike proteins on intact virions. Nature, 588, 2020
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4B8S
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![BU of 4b8s by Molmil](/molmil-images/mine/4b8s) | Crystal Structure of Thermococcus litoralis ADP-dependent Glucokinase (GK) | 分子名称: | ADENOSINE MONOPHOSPHATE, ADP-DEPENDENT GLUCOKINASE, GLYCEROL, ... | 著者 | Herrera-Morande, A, Rivas-Pardo, J.A, Fernandez, F.J, Guixe, V, Vega, M.C. | 登録日 | 2012-08-30 | 公開日 | 2013-07-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Crystal Structure, Saxs and Kinetic Mechanism of Hyperthermophilic Adp-Dependent Glucokinase from Thermococcus Litoralis Reveal a Conserved Mechanism for Catalysis. Plos One, 8, 2013
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5MAP
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![BU of 5map by Molmil](/molmil-images/mine/5map) | X-ray generated oxyferrous complex of DtpA from Streptomyces lividans | 分子名称: | DtpA, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Moreno Chicano, T, Chaplin, A.K, Worrall, J.A.R, Strange, R.W, Hough, M.A. | 登録日 | 2016-11-04 | 公開日 | 2017-05-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Photoreduction and validation of haem-ligand intermediate states in protein crystals by in situ single-crystal spectroscopy and diffraction. IUCrJ, 4, 2017
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1R1L
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![BU of 1r1l by Molmil](/molmil-images/mine/1r1l) | Structure of dimeric antithrombin complexed with a P14-P9 reactive loop peptide and an exogenous tripeptide (formyl-norleucine-LF) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin P14-P9 peptide, Antithrombin-III, ... | 著者 | Zhou, A, Huntington, J.A, Lomas, D.A, Stein, P.E, Carrell, R.W. | 登録日 | 2003-09-24 | 公開日 | 2004-10-05 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Serpins and the design of peptides to block intermolecular beta-linkages To be Published
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5MCZ
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![BU of 5mcz by Molmil](/molmil-images/mine/5mcz) | The structure of the mature HIV-1 CA hexameric lattice with curvature parameters: tilt=-1, twist=0 | 分子名称: | Capsid protein p24 | 著者 | Mattei, S, Glass, B, Hagen, W.J.H, Kraeusslich, H.-G, Briggs, J.A.G. | 登録日 | 2016-11-10 | 公開日 | 2016-12-28 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (8.2 Å) | 主引用文献 | The structure and flexibility of conical HIV-1 capsids determined within intact virions. Science, 354, 2016
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5MDB
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![BU of 5mdb by Molmil](/molmil-images/mine/5mdb) | The structure of the mature HIV-1 CA hexameric lattice with curvature parameters: tilt=17, twist=-6 | 分子名称: | Gag protein | 著者 | Mattei, S, Glass, B, Hagen, W.J.H, Kraeusslich, H.-G, Briggs, J.A.G. | 登録日 | 2016-11-10 | 公開日 | 2016-12-28 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (8.4 Å) | 主引用文献 | The structure and flexibility of conical HIV-1 capsids determined within intact virions. Science, 354, 2016
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3O6H
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![BU of 3o6h by Molmil](/molmil-images/mine/3o6h) | Ligand-binding domain of GluA2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator | 分子名称: | 1,2-ETHANEDIOL, 2-[({4-[(ethylamino)methyl]-3-(trifluoromethyl)-1H-pyrazol-1-yl}acetyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, DIMETHYL SULFOXIDE, ... | 著者 | Maclean, J.K.F, Campbell, R.A, Cumming, I.A, Gillen, K.J, Gillespie, J, Jamieson, C, Kazemier, B, Kiczun, M, Lamont, Y, Lyons, A.J, Martin, F, Moir, E.M, Morrow, J.A, Pantling, J, Rankovic, Z, Smith, L. | 登録日 | 2010-07-29 | 公開日 | 2010-09-15 | 最終更新日 | 2017-08-09 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A novel series of positive modulators of the AMPA receptor: structure-based lead optimization. Bioorg.Med.Chem.Lett., 20, 2010
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4B14
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![BU of 4b14 by Molmil](/molmil-images/mine/4b14) | Plasmodium vivax N-myristoyltransferase with a bound benzofuran inhibitor (compound 26) | 分子名称: | 2-oxopentadecyl-CoA, 3-methoxybenzyl 3-methyl-4-(piperidin-4-yloxy)-1-benzofuran-2-carboxylate, CHLORIDE ION, ... | 著者 | Yu, Z, Brannigan, J.A, Moss, D.K, Brzozowski, A.M, Wilkinson, A.J, Holder, A.A, Tate, E.W, Leatherbarrow, R.J. | 登録日 | 2012-07-06 | 公開日 | 2012-10-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Design and Synthesis of Inhibitors of Plasmodium Falciparum N-Myristoyltransferase, a Promising Target for Anti-Malarial Drug Discovery. J.Med.Chem., 55, 2012
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5MD8
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![BU of 5md8 by Molmil](/molmil-images/mine/5md8) | The structure of the mature HIV-1 CA hexameric lattice with curvature parameters: tilt=17, twist=12 | 分子名称: | Gag protein | 著者 | Mattei, S, Glass, B, Hagen, W.J.H, Kraeusslich, H.-G, Briggs, J.A.G. | 登録日 | 2016-11-10 | 公開日 | 2016-12-28 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (8.6 Å) | 主引用文献 | The structure and flexibility of conical HIV-1 capsids determined within intact virions. Science, 354, 2016
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3NQD
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![BU of 3nqd by Molmil](/molmil-images/mine/3nqd) | Crystal structure of the mutant I96T of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP | 分子名称: | 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, Orotidine 5'-phosphate decarboxylase | 著者 | Fedorov, A.A, Fedorov, E.V, Wood, B.M, Gerlt, J.A, Almo, S.C. | 登録日 | 2010-06-29 | 公開日 | 2011-05-11 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.423 Å) | 主引用文献 | Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site. Biochemistry, 50, 2011
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6ZOX
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![BU of 6zox by Molmil](/molmil-images/mine/6zox) | Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x2 disulphide-bond mutant, G413C, V987C, single Arg S1/S2 cleavage site) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G. | 登録日 | 2020-07-08 | 公開日 | 2020-07-22 | 最終更新日 | 2021-06-02 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | A thermostable, closed SARS-CoV-2 spike protein trimer. Nat.Struct.Mol.Biol., 27, 2020
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1RJ4
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![BU of 1rj4 by Molmil](/molmil-images/mine/1rj4) | Structure of a Cell Wall Invertase Inhibitor from Tobacco in Complex with Cd2+ | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, invertase inhibitor | 著者 | Hothorn, M, D'Angelo, I, Marquez, J.A, Greiner, S, Scheffzek, K. | 登録日 | 2003-11-18 | 公開日 | 2004-02-03 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The invertase inhibitor Nt-CIF from tobacco: a highly thermostable four-helix bundle with an unusual N-terminal extension J.Mol.Biol., 335, 2004
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6ZP2
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![BU of 6zp2 by Molmil](/molmil-images/mine/6zp2) | Structure of SARS-CoV-2 Spike Protein Trimer (K986P, V987P, single Arg S1/S2 cleavage site) in Locked State | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | 著者 | Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G. | 登録日 | 2020-07-08 | 公開日 | 2020-07-22 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | A thermostable, closed SARS-CoV-2 spike protein trimer. Nat.Struct.Mol.Biol., 27, 2020
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1RQ7
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![BU of 1rq7 by Molmil](/molmil-images/mine/1rq7) | MYCOBACTERIUM TUBERCULOSIS FTSZ IN COMPLEX WITH GDP | 分子名称: | Cell division protein ftsZ, GUANOSINE-5'-DIPHOSPHATE | 著者 | Leung, A.K.W, White, E.L, Ross, L.J, Reynolds, R.C, DeVito, J.A, Borhani, D.W. | 登録日 | 2003-12-04 | 公開日 | 2004-08-31 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of Mycobacterium tuberculosis FtsZ reveals unexpected, G protein-like conformational switches. J.Mol.Biol., 342, 2004
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5MCY
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![BU of 5mcy by Molmil](/molmil-images/mine/5mcy) | The structure of the mature HIV-1 CA pentamer in intact virus particles | 分子名称: | Capsid protein p24 | 著者 | Mattei, S, Glass, B, Hagen, W.J.H, Kraeusslich, H.-G, Briggs, J.A.G. | 登録日 | 2016-11-10 | 公開日 | 2016-12-28 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (8.8 Å) | 主引用文献 | The structure and flexibility of conical HIV-1 capsids determined within intact virions. Science, 354, 2016
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5ME8
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![BU of 5me8 by Molmil](/molmil-images/mine/5me8) | N-terminal domain of the human tumor suppressor ING5 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, Inhibitor of growth protein 5 | 著者 | Roversi, P, Blanco, F.J, Rojas, A.L, Buitrago, J.A.R. | 登録日 | 2016-11-14 | 公開日 | 2018-03-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark. J.Mol.Biol., 431, 2019
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1RD3
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![BU of 1rd3 by Molmil](/molmil-images/mine/1rd3) | 2.5A Structure of Anticoagulant Thrombin Variant E217K | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, PHOSPHATE ION, ... | 著者 | Carter, W.J, Myles, T, Leung, L.L, Huntington, J.A. | 登録日 | 2003-11-05 | 公開日 | 2004-05-04 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structure of Anticoagulant Thrombin Variant E217K Provides Insights into Thrombin Allostery J.Biol.Chem., 279, 2004
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4C9I
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![BU of 4c9i by Molmil](/molmil-images/mine/4c9i) | Crystal Structure of the Strawberry Pathogenesis-Related 10 (PR-10) Fra a 1E protein (Form B) | 分子名称: | (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol, GLYCEROL, MAJOR STRAWBERRY ALLERGEN FRA A 1-E | 著者 | Casanal, A, Zander, U, Valpuesta, V, Marquez, J.A. | 登録日 | 2013-10-02 | 公開日 | 2013-10-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The Strawberry Pathogenesis-Related 10 (Pr-10) Fra a Proteins Control Flavonoid Biosynthesis by Binding to Metabolic Intermediates. J.Biol.Chem., 288, 2013
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