3QMC
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![BU of 3qmc by Molmil](/molmil-images/mine/3qmc) | Structural Basis of Selective Binding of Nonmethylated CpG Islands by the CXXC Domain of CFP1 | Descriptor: | 5'-D(*GP*CP*CP*AP*CP*CP*GP*CP*TP*GP*GP*C)-3', 5'-D(*GP*CP*CP*AP*GP*CP*GP*GP*TP*GP*GP*C)-3', CpG-binding protein, ... | Authors: | Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2011-02-04 | Release date: | 2011-02-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain. Nat Commun, 2, 2011
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4JDP
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![BU of 4jdp by Molmil](/molmil-images/mine/4jdp) | Crystal structure of probable p-nitrophenyl phosphatase (pho2) (target EFI-501307) from Archaeoglobus fulgidus DSM 4304 with Magnesium bound | Descriptor: | CHLORIDE ION, MAGNESIUM ION, p-nitrophenyl phosphatase (Pho2) | Authors: | Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Al Obaidi, N, Stead, M, Love, J, Allen, K.N, Dunaway-Mariano, D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2013-02-25 | Release date: | 2013-03-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Crystal structure of probable p-nitrophenyl phosphatase from Archaeoglobus fulgidus. To be Published
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2FSP
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![BU of 2fsp by Molmil](/molmil-images/mine/2fsp) | NMR SOLUTION STRUCTURE OF BACILLUS SUBTILIS SPO0F PROTEIN, MINIMIZED AVERAGE STRUCTURE | Descriptor: | STAGE 0 SPORULATION PROTEIN F | Authors: | Feher, V.A, Skelton, N.J, Dahlquist, F.W, Cavanagh, J. | Deposit date: | 1997-06-06 | Release date: | 1997-12-10 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | High-resolution NMR structure and backbone dynamics of the Bacillus subtilis response regulator, Spo0F: implications for phosphorylation and molecular recognition. Biochemistry, 36, 1997
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4J71
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![BU of 4j71 by Molmil](/molmil-images/mine/4j71) | Crystal Structure of GSK3b in complex with inhibitor 1R | Descriptor: | (2R)-2-methyl-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one, CHLORIDE ION, Glycogen synthase kinase-3 beta, ... | Authors: | Zhan, C, Wang, Y, Wach, J, Sheehan, P, Zhong, C, Harris, R, Patskovsky, Y, Bishop, J, Haggarty, S, Ramek, A, Berry, K, O'Herin, C, Koehler, A.N, Hung, A.W, Young, D.W, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2013-02-12 | Release date: | 2013-03-20 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Fragment-based approach using diversity-oriented synthesis yields a GSK3b inhibitor To be Published
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4AUR
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![BU of 4aur by Molmil](/molmil-images/mine/4aur) | |
4IW9
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![BU of 4iw9 by Molmil](/molmil-images/mine/4iw9) | Crystal structure of glutathione s-transferase mha_0454 (target efi-507015) from mannheimia haemolytica, gsh complex | Descriptor: | ACETATE ION, CHLORIDE ION, GLUTATHIONE, ... | Authors: | Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Al Obaidi, N, Stead, M, Love, J, Gerlt, J.A, Armstrong, R.N, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2013-01-23 | Release date: | 2013-02-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Crystal Structure of Probable Glutathione S-Transferase Mha_0454 (Target Efi-507015) from Mannheimia Haemolytica To be Published
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4J30
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![BU of 4j30 by Molmil](/molmil-images/mine/4j30) | Structure of the effector - immunity system Tae4 / Tai4 from Salmonella typhimurium, selenomethionine variant | Descriptor: | 2-ETHOXYETHANOL, CITRATE ANION, Putative cytoplasmic protein, ... | Authors: | Benz, J, Reinstein, J, Meinhart, A. | Deposit date: | 2013-02-05 | Release date: | 2013-05-22 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Insights into the Effector - Immunity System Tae4/Tai4 from Salmonella typhimurium. Plos One, 8, 2013
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3WUF
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![BU of 3wuf by Molmil](/molmil-images/mine/3wuf) | The mutant crystal structure of b-1,4-Xylanase (XynAS9_V43P/G44E) from Streptomyces sp. 9 | Descriptor: | Endo-1,4-beta-xylanase A, ZINC ION | Authors: | Chen, C.C, Han, X, Lv, P, Ko, T.P, Peng, W, Huang, C.H, Zheng, Y, Gao, J, Yang, Y.Y, Guo, R.T. | Deposit date: | 2014-04-23 | Release date: | 2014-10-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structural perspectives of an engineered beta-1,4-xylanase with enhanced thermostability. J.Biotechnol., 189C, 2014
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1LX8
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![BU of 1lx8 by Molmil](/molmil-images/mine/1lx8) | Regulation of directionality in bacteriophage lambda site-specific recombination: structure of the Xis protein | Descriptor: | Excisionase | Authors: | Sam, M.D, Papagiannis, C, Connolly, K.M, Corselli, L, Iwahara, J, Lee, J, Phillips, M, Wojciak, J.M, Johnson, R.C, Clubb, R.T. | Deposit date: | 2002-06-04 | Release date: | 2003-06-10 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Regulation of directionality in bacteriophage lambda site-specific recombination: structure of the Xis protein J.Mol.Biol., 324, 2002
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1M05
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![BU of 1m05 by Molmil](/molmil-images/mine/1m05) | HLA B8 in complex with an Epstein Barr Virus determinant | Descriptor: | Beta-2-microglobulin, CADMIUM ION, EBNA-3 nuclear protein, ... | Authors: | Kjer-Nielsen, L, Clements, C.S, Brooks, A.G, Purcell, A.W, Fontes, M.R, McCluskey, J, Rossjohn, J. | Deposit date: | 2002-06-11 | Release date: | 2003-09-02 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structure of HLA-B8 complexed to an immunodominant viral determinant: peptide-induced conformational changes and
a mode of MHC class I dimerization. J.IMMUNOL., 169, 2003
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3H3B
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![BU of 3h3b by Molmil](/molmil-images/mine/3h3b) | Crystal structure of the single-chain Fv (scFv) fragment of an anti-ErbB2 antibody chA21 in complex with residues 1-192 of ErbB2 extracellular domain | Descriptor: | Receptor tyrosine-protein kinase erbB-2, anti-ErbB2 antibody chA21 | Authors: | Zhou, H, Liu, Y, Niu, L, Zhu, J, Teng, M. | Deposit date: | 2009-04-16 | Release date: | 2010-04-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural Insights into the Down-regulation of Overexpressed p185her2/neu Protein of Transformed Cells by the Antibody chA21. J.Biol.Chem., 286, 2011
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2QIN
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![BU of 2qin by Molmil](/molmil-images/mine/2qin) | |
3H5W
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![BU of 3h5w by Molmil](/molmil-images/mine/3h5w) | Crystal structure of the GluR2-ATD in space group P212121 without solvent | Descriptor: | Glutamate receptor 2 | Authors: | Jin, R, Singh, S.K, Gu, S, Furukawa, H, Sobolevsky, A, Zhou, J, Jin, Y, Gouaux, E. | Deposit date: | 2009-04-22 | Release date: | 2009-06-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.686 Å) | Cite: | Crystal structure and association behaviour of the GluR2 amino-terminal domain. Embo J., 28, 2009
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3GM2
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![BU of 3gm2 by Molmil](/molmil-images/mine/3gm2) | |
4IT1
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![BU of 4it1 by Molmil](/molmil-images/mine/4it1) | Crystal structure of enolase pfl01_3283 (target efi-502286) from pseudomonas fluorescens pf0-1 with bound magnesium, potassium and tartrate | Descriptor: | BICARBONATE ION, L(+)-TARTARIC ACID, MAGNESIUM ION, ... | Authors: | Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Al Obaidi, N, Stead, M, Love, J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2013-01-17 | Release date: | 2013-01-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of Enolase Pfl01_3283 from Pseudomonas Fluorescens To be Published
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3H6K
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![BU of 3h6k by Molmil](/molmil-images/mine/3h6k) | |
2QL7
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![BU of 2ql7 by Molmil](/molmil-images/mine/2ql7) | Crystal Structure of Caspase-7 with inhibitor AC-IEPD-CHO | Descriptor: | CITRIC ACID, Caspase-7, Inhibitor AC-IEPD_CHO, ... | Authors: | Agniswamy, J, Fang, B, Weber, I. | Deposit date: | 2007-07-12 | Release date: | 2007-08-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis. Febs J., 274, 2007
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4JUH
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![BU of 4juh by Molmil](/molmil-images/mine/4juh) | Crystal structure of 1918 pandemic influenza virus hemagglutinin mutant D225G complexed with avian receptor analogue LSTa | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Zhang, W, Shi, Y, Qi, J, Gao, F, Li, Q, Fan, Z, Yan, J, Gao, G.F. | Deposit date: | 2013-03-24 | Release date: | 2013-05-01 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.805 Å) | Cite: | Molecular basis of the receptor binding specificity switch of the hemagglutinins from both the 1918 and 2009 pandemic influenza A viruses by a D225G substitution J.Virol., 87, 2013
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1DAR
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![BU of 1dar by Molmil](/molmil-images/mine/1dar) | ELONGATION FACTOR G IN COMPLEX WITH GDP | Descriptor: | ELONGATION FACTOR G, GUANOSINE-5'-DIPHOSPHATE | Authors: | Al-Karadaghi, S, Aevarsson, A, Garber, M, Zheltonosova, J, Liljas, A. | Deposit date: | 1996-02-15 | Release date: | 1996-07-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The structure of elongation factor G in complex with GDP: conformational flexibility and nucleotide exchange. Structure, 4, 1996
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2QLB
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![BU of 2qlb by Molmil](/molmil-images/mine/2qlb) | Crystal Structure of caspase-7 with inhibitor AC-ESMD-CHO | Descriptor: | CITRIC ACID, Caspase-7, Inhibitor AC-ESMD-CHO, ... | Authors: | Agniswamy, J, Fang, B, Weber, I. | Deposit date: | 2007-07-12 | Release date: | 2007-08-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis. Febs J., 274, 2007
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3TQV
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![BU of 3tqv by Molmil](/molmil-images/mine/3tqv) | Structure of the nicotinate-nucleotide pyrophosphorylase from Francisella tularensis. | Descriptor: | Nicotinate-nucleotide pyrophosphorylase, PHOSPHATE ION | Authors: | Rudolph, M, Cheung, J, Franklin, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | Deposit date: | 2011-09-09 | Release date: | 2011-09-28 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | Rapid countermeasure discovery against Francisella tularensis based on a metabolic network reconstruction. Plos One, 8, 2013
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4JRX
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![BU of 4jrx by Molmil](/molmil-images/mine/4jrx) | Crystal Structure of CA5 TCR-HLA B*3505-LPEP complex | Descriptor: | Beta-2-microglobulin, CA5 TCR alpha chain, CA5 TCR beta chain, ... | Authors: | Liu, Y.C, Rossjohn, J, Gras, S. | Deposit date: | 2013-03-22 | Release date: | 2013-04-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Highly divergent T-cell receptor binding modes underlie specific recognition of a bulged viral peptide bound to a human leukocyte antigen class I molecule. J.Biol.Chem., 288, 2013
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2QZ4
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![BU of 2qz4 by Molmil](/molmil-images/mine/2qz4) | Human paraplegin, AAA domain in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Paraplegin | Authors: | Karlberg, T, Lehtio, L, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Herman, M.D, Johansson, I, Kallas, A, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, J, Sagemark, C, Sundstrom, M, Thorsell, A.G, Tresauges, L, Van Den Berg, S, Weigelt, J, Welin, M, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC) | Deposit date: | 2007-08-16 | Release date: | 2007-09-11 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Crystal Structure of the ATPase Domain of the Human AAA+ Protein Paraplegin/SPG7. Plos One, 4, 2009
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4JV9
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![BU of 4jv9 by Molmil](/molmil-images/mine/4jv9) | Co-crystal structure of MDM2 with inhibitor (2S,5R,6S)-2-benzyl-5,6-bis(4-chlorophenyl)-4-methylmorpholin-3-one | Descriptor: | (2S,5R,6S)-2-benzyl-5,6-bis(4-chlorophenyl)-4-methylmorpholin-3-one, E3 ubiquitin-protein ligase Mdm2, SULFATE ION | Authors: | Huang, X, Gonzalez-Lopez de Turiso, F, Sun, D, Yosup, R, Bartberger, M.D, Beck, H.P, Cannon, J, Shaffer, P, Oliner, J.D, Olson, S.H, Medina, J.C. | Deposit date: | 2013-03-25 | Release date: | 2013-05-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Rational Design and Binding Mode Duality of MDM2-p53 Inhibitors. J.Med.Chem., 56, 2013
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3H5V
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![BU of 3h5v by Molmil](/molmil-images/mine/3h5v) | Crystal structure of the GluR2-ATD | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2 | Authors: | Jin, R, Singh, S.K, Gu, S, Furukawa, H, Sobolevsky, A, Zhou, J, Jin, Y, Gouaux, E. | Deposit date: | 2009-04-22 | Release date: | 2009-06-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Crystal structure and association behaviour of the GluR2 amino-terminal domain. Embo J., 28, 2009
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