2A5U
 
 | | Crystal Structure of human PI3Kgamma complexed with AS605240 | | 分子名称: | (5E)-5-(QUINOXALIN-6-YLMETHYLENE)-1,3-THIAZOLIDINE-2,4-DIONE, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, gamma isoform | | 著者 | Camps, M, Ruckle, T, Ji, H, Ardissone, V, Rintelen, F, Shaw, J, Ferrandi, C, Chabert, C, Gillieron, C, Francon, B, Martin, T, Gretener, D, Perrin, D, Leroy, D, Vitte, P.-A, Hirsch, E, Wymann, M.P, Cirillo, R, Schwarz, M.K, Rommel, C. | | 登録日 | 2005-07-01 | | 公開日 | 2005-09-20 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis
NAT.MED. (N.Y.), 11, 2005
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2A3Y
 | | Pentameric crystal structure of human serum amyloid P-component bound to Bis-1,2-{[(Z)-2carboxy-2-methyl-1,3-dioxane]-5-yloxycarbamoyl}-ethane. | | 分子名称: | BIS-1,2-{[(Z)-2-CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBAMOYL}-ETHANE, CALCIUM ION, Serum amyloid P-component | | 著者 | Ho, J.G, Kitov, P.I, Paszkiewicz, E, Sadowska, J, Bundle, D.R, Ng, K.K. | | 登録日 | 2005-06-27 | | 公開日 | 2005-07-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Ligand-assisted Aggregation of Proteins: DIMERIZATION OF SERUM AMYLOID P COMPONENT BY BIVALENT LIGANDS.
J.Biol.Chem., 280, 2005
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2A3K
 | | Crystal Structure of the Human Protein Tyrosine Phosphatase, PTPN7 (HePTP, Hematopoietic Protein Tyrosine Phosphatase) | | 分子名称: | PHOSPHATE ION, protein tyrosine phosphatase, non-receptor type 7, ... | | 著者 | Barr, A, Turnbull, A.P, Das, S, Eswaran, J, Debreczeni, J.E, Longmann, E, Smee, C, Burgess, N, Gileadi, O, Sundstrom, M, Arrowsmith, C, Edwards, A, von Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2005-06-24 | | 公開日 | 2005-07-19 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | The crystal structure of human receptor protein tyrosine phosphatase kappa phosphatase domain 1.
Protein Sci., 15, 2006
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2A7S
 | | Crystal Structure of the Acyl-CoA Carboxylase, AccD5, from Mycobacterium tuberculosis | | 分子名称: | Probable propionyl-CoA carboxylase beta chain 5 | | 著者 | Lin, T, Melgar, M, Purdon, J, Tseng, T, Tsai, S.C. | | 登録日 | 2005-07-06 | | 公開日 | 2006-02-21 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure-based inhibitor design of AccD5, an essential acyl-CoA carboxylase carboxyltransferase domain of Mycobacterium tuberculosis.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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2AAO
 | | Regulatory apparatus of Calcium Dependent protein kinase from Arabidopsis thaliana | | 分子名称: | CALCIUM ION, Calcium-dependent protein kinase, isoform AK1 | | 著者 | Chandran, V, Stollar, E.J, Lindorff-Larsen, K, Harper, J.F, Chazin, W.J, Dobson, C.M, Luisi, B.F, Christodoulou, J. | | 登録日 | 2005-07-13 | | 公開日 | 2005-12-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of the regulatory apparatus of a calcium-dependent protein kinase (CDPK): a novel mode of calmodulin-target recognition.
J.Mol.Biol., 357, 2006
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2A0L
 | | Crystal structure of KvAP-33H1 Fv complex | | 分子名称: | 33H1 Fv fragment, POTASSIUM ION, Voltage-gated potassium channel | | 著者 | Lee, S.Y, Lee, A, Chen, J, Mackinnon, R. | | 登録日 | 2005-06-16 | | 公開日 | 2005-11-01 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Structure of the KvAP voltage-dependent K+ channel and its dependence on the lipid membrane.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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2A3W
 | | Decameric structure of human serum amyloid P-component bound to Bis-1,2-{[(Z)-2-carboxy-2-methyl-1,3-dioxane]-5-yloxycarbamoyl}-ethane | | 分子名称: | BIS-1,2-{[(Z)-2-CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBAMOYL}-ETHANE, CALCIUM ION, Serum amyloid P-component | | 著者 | Ho, J.G, Kitov, P.I, Paszkiewicz, E, Sadowska, J, Bundle, D.R, Ng, K.K. | | 登録日 | 2005-06-27 | | 公開日 | 2005-07-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Ligand-assisted Aggregation of Proteins: DIMERIZATION OF SERUM AMYLOID P COMPONENT BY BIVALENT LIGANDS.
J.Biol.Chem., 280, 2005
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2A3X
 | | Decameric crystal structure of human serum amyloid P-component bound to Bis-1,2-{[(Z)-2carboxy- 2-methyl-1,3-dioxane]- 5-yloxycarbonyl}-piperazine | | 分子名称: | BIS-1,2-{[(Z)-2CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBONYL}-PIPERAZINE, CALCIUM ION, Serum amyloid P-component | | 著者 | Ho, J.G, Kitov, P.I, Paszkiewicz, E, Sadowska, J, Bundle, D.R, Ng, K.K. | | 登録日 | 2005-06-27 | | 公開日 | 2005-07-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Ligand-assisted Aggregation of Proteins: DIMERIZATION OF SERUM AMYLOID P COMPONENT BY BIVALENT LIGANDS.
J.Biol.Chem., 280, 2005
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2A5A
 | | Crystal structure of unbound SARS coronavirus main peptidase in the space group C2 | | 分子名称: | 1,2-ETHANEDIOL, 3C-like peptidase, CHLORIDE ION | | 著者 | Lee, T.-W, Cherney, M.M, Huitema, C, Liu, J, James, K.E, Powers, J.C, Eltis, L.D, James, M.N. | | 登録日 | 2005-06-30 | | 公開日 | 2005-10-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Crystal Structures of the Main Peptidase from the SARS Coronavirus Inhibited by a Substrate-like Aza-peptide Epoxide
J.Mol.Biol., 353, 2005
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2A9W
 | | E. coli TS complexed with dUMP and inhibitor GA9 | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-BROMOPHENOL, 3,3-BIS(3-BROMO-4-HYDROXYPHENYL)-7-CHLORO-1H,3H-BENZO[DE]ISOCHROMEN-1-ONE, ... | | 著者 | Finer-Moore, J.S, Anderson, A.C, O'Neil, R.H, Costi, M.P, Ferrari, S, Krucinski, J, Stroud, R.M. | | 登録日 | 2005-07-12 | | 公開日 | 2005-10-11 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The structure of Cryptococcus neoformans thymidylate synthase suggests strategies for using target dynamics for species-specific inhibition.
Acta Crystallogr.,Sect.D, 61, 2005
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2AD6
 | | crystal structure of methanol dehydrogenase from M. W3A1 (form C) | | 分子名称: | CALCIUM ION, Methanol dehydrogenase subunit 1, Methanol dehydrogenase subunit 2, ... | | 著者 | Li, J, Gan, J.-H, Xia, Z.-X, Mathews, F.S. | | 登録日 | 2005-07-20 | | 公開日 | 2006-07-25 | | 最終更新日 | 2013-09-18 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The enzymatic reaction-induced configuration change of the prosthetic group PQQ of methanol dehydrogenase
Biochem.Biophys.Res.Commun., 406, 2011
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2A0J
 | | Crystal Structure of Nitrogen Regulatory Protein IIA-Ntr from Neisseria meningitidis | | 分子名称: | PTS system, nitrogen regulatory IIA protein | | 著者 | Ren, J, Sainsbury, S, Berrow, N.S, Alderton, D, Nettleship, J.E, Stammers, D.K, Saunders, N.J, Owens, R.J, Oxford Protein Production Facility (OPPF) | | 登録日 | 2005-06-16 | | 公開日 | 2005-09-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of nitrogen regulatory protein IIANtr from Neisseria meningitidis
Bmc Struct.Biol., 5, 2005
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2A9F
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2A4K
 | | 3-Oxoacyl-[acyl carrier protein] reductase from Thermus thermophilus TT0137 | | 分子名称: | 3-oxoacyl-[acyl carrier protein] reductase, UNKNOWN ATOM OR ION | | 著者 | Zhou, W, Ebihara, A, Tempel, W, Yokoyama, S, Chen, L, Kuramitsu, S, Nguyen, J, Chang, S.-H, Liu, Z.-J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-06-29 | | 公開日 | 2006-01-10 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | | 主引用文献 | 3-Oxoacyl-[acyl carrier protein] reductase from Thermus thermophilus TT0137
To be Published
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2A7W
 | | Crystal Structure of Phosphoribosyl-ATP Pyrophosphatase from Chromobacterium violaceum (ATCC 12472). NESG TARGET CVR7 | | 分子名称: | Phosphoribosyl-ATP pyrophosphatase | | 著者 | Benach, J, Forouhar, F, Kuzin, A.P, Abashidze, M, Vorobiev, S.M, Rong, X, Acton, T.B, Montelione, G.T, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2005-07-06 | | 公開日 | 2005-10-25 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structure of Phosphoribosyl-ATP Pyrophosphatase from Chromobacterium violaceum. NESG Target CVR7.
To be Published
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2AD8
 | | crystal structure of methanol dehydrogenase from M. W3A1 (form C) in the presence of ethanol | | 分子名称: | CALCIUM ION, Methanol dehydrogenase subunit 1, Methanol dehydrogenase subunit 2, ... | | 著者 | Li, J, Gan, J.-H, Xia, Z.-X, Mathews, F.S. | | 登録日 | 2005-07-20 | | 公開日 | 2006-07-25 | | 最終更新日 | 2013-09-18 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The enzymatic reaction-induced configuration change of the prosthetic group PQQ of methanol dehydrogenase
Biochem.Biophys.Res.Commun., 406, 2011
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3TQD
 | | Structure of the 3-deoxy-D-manno-octulosonate cytidylyltransferase (kdsB) from Coxiella burnetii | | 分子名称: | 3-deoxy-manno-octulosonate cytidylyltransferase, ACETATE ION, NICKEL (II) ION | | 著者 | Franklin, M.C, Cheung, J, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | | 登録日 | 2011-09-09 | | 公開日 | 2011-10-26 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural genomics for drug design against the pathogen Coxiella burnetii.
Proteins, 83, 2015
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3TR3
 | | Structure of a bolA protein homologue from Coxiella burnetii | | 分子名称: | BolA, COBALT (II) ION | | 著者 | Cheung, J, Franklin, M.C, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | | 登録日 | 2011-09-09 | | 公開日 | 2011-09-28 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.456 Å) | | 主引用文献 | Structural genomics for drug design against the pathogen Coxiella burnetii.
Proteins, 83, 2015
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2A1F
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2A5E
 | | SOLUTION NMR STRUCTURE OF TUMOR SUPPRESSOR P16INK4A, RESTRAINED MINIMIZED MEAN STRUCTURE | | 分子名称: | TUMOR SUPPRESSOR P16INK4A | | 著者 | Byeon, I.-J.L, Li, J, Ericson, K, Selby, T.L, Tevelev, A, Kim, H.-J, O'Maille, P, Tsai, M.-D. | | 登録日 | 1998-02-13 | | 公開日 | 1999-08-13 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Tumor suppressor p16INK4A: determination of solution structure and analyses of its interaction with cyclin-dependent kinase 4.
Mol.Cell, 1, 1998
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3TQQ
 | | Structure of the methionyl-tRNA formyltransferase (fmt) from Coxiella burnetii | | 分子名称: | Methionyl-tRNA formyltransferase, POTASSIUM ION | | 著者 | Rudolph, M, Cheung, J, Franklin, M.C, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | | 登録日 | 2011-09-09 | | 公開日 | 2011-09-28 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural genomics for drug design against the pathogen Coxiella burnetii.
Proteins, 83, 2015
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2ABY
 | | Solution structure of TA0743 from Thermoplasma acidophilum | | 分子名称: | hypothetical protein TA0743 | | 著者 | Kim, B, Jung, J, Hong, E, Yee, A, Arrowsmith, C.H, Lee, W. | | 登録日 | 2005-07-18 | | 公開日 | 2006-08-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of the conserved novel-fold protein TA0743 from Thermoplasma acidophilum.
Proteins, 62, 2006
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3TR4
 | | Structure of an inorganic pyrophosphatase (ppa) from Coxiella burnetii | | 分子名称: | Inorganic pyrophosphatase, MAGNESIUM ION, MANGANESE (II) ION | | 著者 | Cheung, J, Franklin, M.C, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | | 登録日 | 2011-09-09 | | 公開日 | 2011-10-19 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural genomics for drug design against the pathogen Coxiella burnetii.
Proteins, 83, 2015
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2AE1
 | | TROPINONE REDUCTASE-II | | 分子名称: | TROPINONE REDUCTASE-II | | 著者 | Nakajima, K, Yamashita, A, Akama, H, Nakatsu, T, Kato, H, Hashimoto, T, Oda, J, Yamada, Y. | | 登録日 | 1997-10-27 | | 公開日 | 1998-11-18 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structures of two tropinone reductases: different reaction stereospecificities in the same protein fold.
Proc.Natl.Acad.Sci.USA, 95, 1998
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2A83
 | | Crystal structure of hla-b*2705 complexed with the glucagon receptor (gr) peptide (residues 412-420) | | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | | 著者 | Ruckert, C, Fiorillo, M.T, Loll, B, Moretti, R, Biesiadka, J, Saenger, W, Ziegler, A, Sorrentino, R, Uchanska-Ziegler, B. | | 登録日 | 2005-07-07 | | 公開日 | 2005-12-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Conformational dimorphism of self-peptides and molecular mimicry in a disease-associated HLA-B27 subtype.
J.Biol.Chem., 281, 2006
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