6MTC
 
 | | Rabbit 80S ribosome with Z-site tRNA and IFRD2 (unrotated state) | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | 著者 | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | | 登録日 | 2018-10-19 | | 公開日 | 2018-11-21 | | 最終更新日 | 2019-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
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5ULT
 | | HIV-1 wild Type protease with GRL-100-13A (a Crown-like Oxotricyclic Core as the P2-Ligand with the sulfonamide isostere as the P2' group) | | 分子名称: | (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, CHLORIDE ION, Protease, ... | | 著者 | Wang, Y.-F, Agniswamy, J, Weber, I.T. | | 登録日 | 2017-01-25 | | 公開日 | 2017-05-03 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Design and Development of Highly Potent HIV-1 Protease Inhibitors with a Crown-Like Oxotricyclic Core as the P2-Ligand To Combat Multidrug-Resistant HIV Variants.
J. Med. Chem., 60, 2017
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6MZE
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2B4T
 | | Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum at 2.25 Angstrom resolution reveals intriguing extra electron density in the active site | | 分子名称: | 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, glyceraldehyde-3-phosphate dehydrogenase | | 著者 | Robien, M.A, Bosch, J, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) | | 登録日 | 2005-09-26 | | 公開日 | 2005-10-04 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum at 2.25 A resolution reveals intriguing extra electron density in the active site
Proteins, 62, 2006
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2B06
 | | Crystal structure of the MutT/nudix family protein from Streptococcus pneumoniae | | 分子名称: | MAGNESIUM ION, MutT/nudix family protein | | 著者 | Zhang, R, Zhou, M, Abdullah, J, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2005-09-13 | | 公開日 | 2006-01-10 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | The 1.4 A crystal structure of the MutT/nudix family protein from Streptococcus pneumoniae
To be Published
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5UIY
 | | Structure of Bromodomain from human BAZ1A | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bromodomain adjacent to zinc finger domain protein 1A | | 著者 | Oppikofer, M, Sudhamsu, J. | | 登録日 | 2017-01-16 | | 公開日 | 2017-07-12 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.687 Å) | | 主引用文献 | Non-canonical reader modules of BAZ1A promote recovery from DNA damage.
Nat Commun, 8, 2017
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2B0O
 | | Crystal structure of UPLC1 GAP domain | | 分子名称: | UPLC1, ZINC ION | | 著者 | Ismail, S, Shen, L, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2005-09-14 | | 公開日 | 2005-09-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Structural analysis of GAP and ankyrin domains of UPLC1
To be Published
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5UK0
 | | CryoEM structure of an influenza virus receptor-binding site antibody-antigen interface - Class 2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... | | 著者 | Liu, Y, Pan, J, Caradonna, T, Jenni, S, Raymond, D.D, Schmidt, A.G, Harrison, S.C, Grigorieff, N. | | 登録日 | 2017-01-19 | | 公開日 | 2017-05-31 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | CryoEM Structure of an Influenza Virus Receptor-Binding Site Antibody-Antigen Interface.
J. Mol. Biol., 429, 2017
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6N9H
 | | De novo designed homo-trimeric amantadine-binding protein | | 分子名称: | (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine, SODIUM ION, amantadine-binding protein | | 著者 | Park, J, Baker, D. | | 登録日 | 2018-12-03 | | 公開日 | 2019-12-18 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.039 Å) | | 主引用文献 | De novo design of a homo-trimeric amantadine-binding protein.
Elife, 8, 2019
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1D3I
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6MJX
 | | human cGAS catalytic domain bound with cGAMP | | 分子名称: | Cyclic GMP-AMP synthase, ZINC ION, cGAMP | | 著者 | Lama, L, Adura, C, Xie, W, Tomita, D, Kamei, T, Kuryavyi, V, Gogakos, T, Steinberg, J.I, Miller, M, Ramos-Espiritu, L, Asano, Y, Hashizume, S, Aida, J, Imaeda, T, Okamoto, R, Jennings, A.J, Michinom, M, Kuroita, T, Stamford, A, Gao, P, Meinke, P, Glickman, J.F, Patel, D.J, Tuschl, T. | | 登録日 | 2018-09-23 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression.
Nat Commun, 10, 2019
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1D3E
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2YON
 | | Solution NMR structure of the C-terminal extension of two bacterial light, oxygen, voltage (LOV) photoreceptor proteins from Pseudomonas putida | | 分子名称: | SENSORY BOX PROTEIN | | 著者 | Rani, R, Hartmann, R, Lecher, J, Krauss, U, Jaeger, K, Willbold, D. | | 登録日 | 2012-10-25 | | 公開日 | 2013-07-10 | | 最終更新日 | 2019-10-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Conservation of Dark Recovery Kinetic Parameters and Structural Features in the Pseudomonadaceae "Short" Light, Oxygen, Voltage (Lov) Protein Family: Implications for the Design of Lov-Based Optogenetic Tools.
Biochemistry, 52, 2013
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2YAV
 | | ZN INHIBITED SULFUR OXYGENASE REDUCTASE | | 分子名称: | ACETATE ION, CHLORIDE ION, FE (III) ION, ... | | 著者 | Veith, A, Urich, T, Seyfarth, K, Protze, J, Frazao, C, Kletzin, A. | | 登録日 | 2011-02-25 | | 公開日 | 2011-12-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | | 主引用文献 | Substrate Pathways and Mechanisms of Inhibition in the Sulfur Oxygenase Reductase of Acidianus Ambivalens.
Front.Microbiol., 2, 2011
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2YP9
 | | Haemagglutinin of 2005 Human H3N2 Virus in Complex with Avian Receptor Analogue 3SLN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Xiong, X, Lin, Y.P, Wharton, S.A, Martin, S.R, Coombs, P.J, Vachieri, S.G, Christodoulou, E, Walker, P.A, Liu, J, Skehel, J.J, Gamblin, S.J, Hay, A.J, Daniels, R.S, McCauley, J.W. | | 登録日 | 2012-10-29 | | 公開日 | 2012-11-07 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
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2B4C
 | | Crystal structure of HIV-1 JR-FL gp120 core protein containing the third variable region (V3) complexed with CD4 and the X5 antibody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, T-cell surface glycoprotein CD4, ... | | 著者 | Huang, C, Tang, M, Zhang, M.Y, Majeed, S, Montabana, E, Stanfield, R.L, Dimitrov, D.S, Korber, B, Sodroski, J, Wilson, I.A, Wyatt, R, Kwong, P.D. | | 登録日 | 2005-09-23 | | 公開日 | 2005-11-15 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of a V3-containing HIV-1 gp120 core.
Science, 310, 2005
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1CTP
 | | STRUCTURE OF THE MAMMALIAN CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE AND AN INHIBITOR PEPTIDE DISPLAYS AN OPEN CONFORMATION | | 分子名称: | MYRISTIC ACID, cAMP-DEPENDENT PROTEIN KINASE, cAMP-dependent protein kinase inhibitor, ... | | 著者 | Karlsson, R, Zheng, J, Xuong, N.H, Taylor, S.S, Sowadski, J.M. | | 登録日 | 1993-04-08 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure of the mammalian catalytic subunit of cAMP-dependent protein kinase and an inhibitor peptide displays an open conformation.
Acta Crystallogr.,Sect.D, 49, 1993
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1P7L
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2B6C
 | | Predicted DNA alkylation repair enzyme from Enterococcus faecalis. | | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, GLYCEROL, ... | | 著者 | Osipiuk, J, Hatzos, C, Moy, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2005-09-30 | | 公開日 | 2005-11-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Xray structure of predicted DNA alkylation repair enzyme from Enterococcus faecalis.
To be Published
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6NMI
 | | Cryo-EM structure of the human TFIIH core complex | | 分子名称: | CDK-activating kinase assembly factor MAT1, General transcription and DNA repair factor IIH helicase subunit XPB, General transcription and DNA repair factor IIH helicase subunit XPD, ... | | 著者 | Greber, B.J, Toso, D, Fang, J, Nogales, E. | | 登録日 | 2019-01-10 | | 公開日 | 2019-03-13 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | The complete structure of the human TFIIH core complex.
Elife, 8, 2019
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2Y8T
 | | Co-structure of AMA1 with a surface exposed region of RON2 from Toxoplasma gondii | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, APICAL MEMBRANE ANTIGEN, PUTATIVE, ... | | 著者 | Tonkin, M.L, Roques, M, Lamarque, M.H, Pugniere, M, Douguet, D, Crawford, J, Lebrun, M, Boulanger, M.J. | | 登録日 | 2011-02-10 | | 公開日 | 2011-08-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Host Cell Invasion by Apicomplexan Parasites: Insights from the Co-Structure of Ama1 with a Ron2 Peptide
Science, 333, 2011
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6NO0
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4I80
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2B0V
 | | NUDIX hydrolase from Nitrosomonas europaea. | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, NUDIX hydrolase, ... | | 著者 | Osipiuk, J, Skarina, T, Savchenko, A, Edwards, A, Joachimiak, A, MCSG, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2005-09-14 | | 公開日 | 2005-09-27 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | X-ray structure of NUDIX hydrolase from Nitrosomonas europaea.
To be Published
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2B22
 | | Antiparallel four-stranded coiled coil specified by a 3-3-1 hydrophobic heptad repeat | | 分子名称: | General control protein GCN4, SODIUM ION | | 著者 | Deng, Y, Liu, J, Zheng, Q, Eliezer, D, Kallenbach, N.R, Lu, M. | | 登録日 | 2005-09-16 | | 公開日 | 2006-01-31 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Antiparallel four-stranded coiled coil specified by a 3-3-1 hydrophobic heptad repeat.
Structure, 14, 2006
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