8W83
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![BU of 8w83 by Molmil](/molmil-images/mine/8w83) | HLA-DQ2.5-alpha1 gliadin peptide in complex with DQN0344AE02 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DQN0344AE02 Fab heavy chain, DQN0344AE02 Fab light chain, ... | 著者 | Irie, M, Tsushima, T, Teranishi-Ikawa, Y, Takahashi, N, Ishii, S, Okura, Y, Fukami, T.A, Torizawa, T. | 登録日 | 2023-08-31 | 公開日 | 2023-11-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.818 Å) | 主引用文献 | Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease. Nat Commun, 14, 2023
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8GV0
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![BU of 8gv0 by Molmil](/molmil-images/mine/8gv0) | Crystal structure of anti-FIXa IgG fab without FAST-Ig mutations | 分子名称: | Anti-factor IXa IgG fab heavy chain, Anti-factor IXa IgG fab light chain | 著者 | Koga, H, Yamano, T, Fukami, T.A, Sampei, Z, Shiraiwa, H, Torizawa, T. | 登録日 | 2022-09-14 | 公開日 | 2023-06-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.192 Å) | 主引用文献 | Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A. Mabs, 15, 2023
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5IX5
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![BU of 5ix5 by Molmil](/molmil-images/mine/5ix5) | NMR structure of antibacterial factor-2 | 分子名称: | Antibacterial factor-related peptide 2 | 著者 | Masakatsu, K, Umetsu, Y, Rumi, F, Kikukawa, T, Ohki, S, Mizuguchi, M, Demura, M, Aizawa, T. | 登録日 | 2016-03-23 | 公開日 | 2017-03-29 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of ABF-2 (antibacterial factor-2) from C. elegans and the interaction with membrane mimetic systems To Be Published
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4WIB
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![BU of 4wib by Molmil](/molmil-images/mine/4wib) | Crystal structure of Magnesium transporter MgtE | 分子名称: | CALCIUM ION, Magnesium transporter MgtE | 著者 | Takeda, H, Hattori, M, Nishizawa, T, Yamashita, K, Shah, S.T.A, Caffrey, M, Maturana, A.D, Ishitani, R, Nureki, O. | 登録日 | 2014-09-25 | 公開日 | 2014-12-03 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for ion selectivity revealed by high-resolution crystal structure of Mg(2+) channel MgtE Nat Commun, 5, 2014
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5GLH
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![BU of 5glh by Molmil](/molmil-images/mine/5glh) | Human endothelin receptor type-B in complex with ET-1 | 分子名称: | Endothelin Receptor Subtype-B, Peptide from Endothelin-1 | 著者 | Shihoya, W, Nishizawa, T, Okuta, A, Tani, K, Fujiyoshi, Y, Dohmae, N, Nureki, O, Doi, T. | 登録日 | 2016-07-11 | 公開日 | 2016-09-07 | 最終更新日 | 2020-02-26 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Activation mechanism of endothelin ETB receptor by endothelin-1. Nature, 537, 2016
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4X5M
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![BU of 4x5m by Molmil](/molmil-images/mine/4x5m) | Crystal structure of SemiSWEET in the inward-open conformation | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, OLEIC ACID, ... | 著者 | Lee, Y, Nishizawa, T, Yamashita, K, Ishitani, R, Nureki, O. | 登録日 | 2014-12-05 | 公開日 | 2015-01-21 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for the facilitative diffusion mechanism by SemiSWEET transporter Nat Commun, 6, 2015
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7BTW
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![BU of 7btw by Molmil](/molmil-images/mine/7btw) | The mitochondrial SAM complex from S.cere | 分子名称: | Mitochondrial outer membrane beta-barrel protein, SAM37 isoform 1, Sorting assembly machinery 35 kDa subunit | 著者 | Takeda, H, Tsutsumi, A, Nishizawa, T, Nureki, O, Kikkawa, M, Endo, T. | 登録日 | 2020-04-03 | 公開日 | 2021-01-20 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Mitochondrial sorting and assembly machinery operates by beta-barrel switching. Nature, 590, 2021
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7BTX
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![BU of 7btx by Molmil](/molmil-images/mine/7btx) | The mitochondrial SAM-Mdm10 supercomplex in GDN micelle from S.cere | 分子名称: | MDM10 isoform 1, Mitochondrial outer membrane beta-barrel protein, Sorting assembly machinery 35 kDa subunit, ... | 著者 | Takeda, H, Tsutsumi, A, Nishizawa, T, Nureki, O, Kikkawa, M, Endo, T. | 登録日 | 2020-04-03 | 公開日 | 2021-01-20 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Mitochondrial sorting and assembly machinery operates by beta-barrel switching. Nature, 590, 2021
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7BTY
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![BU of 7bty by Molmil](/molmil-images/mine/7bty) | The mitochondrial SAM-Mdm10 supercomplex in Nanodisc from S.cere | 分子名称: | MDM10 isoform 1, Mitochondrial outer membrane beta-barrel protein, Sorting assembly machinery 35 kDa subunit, ... | 著者 | Takeda, H, Tsutsumi, A, Nishizawa, T, Nureki, O, Kikkawa, M, Endo, T. | 登録日 | 2020-04-03 | 公開日 | 2021-01-20 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Mitochondrial sorting and assembly machinery operates by beta-barrel switching. Nature, 590, 2021
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8GUJ
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![BU of 8guj by Molmil](/molmil-images/mine/8guj) | Bre1-nucleosome complex (Model II) | 分子名称: | DNA (147-mer), E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, ... | 著者 | Onishi, S, Sato, K, Hamada, K, Nishizawa, T, Nureki, O, Ogata, K, Sengoku, T. | 登録日 | 2022-09-12 | 公開日 | 2023-09-20 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structure of the human Bre1 complex bound to the nucleosome. Nat Commun, 15, 2024
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8GUK
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![BU of 8guk by Molmil](/molmil-images/mine/8guk) | Human nucleosome core particle (free form) | 分子名称: | DNA (147-mer), Histone H2A type 1, Histone H2B type 1-J, ... | 著者 | Onishi, S, Sato, K, Nishizawa, T, Nureki, O, Ogata, K, Sengoku, T. | 登録日 | 2022-09-12 | 公開日 | 2023-09-20 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.51 Å) | 主引用文献 | Structure of the human Bre1 complex bound to the nucleosome. Nat Commun, 15, 2024
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8GUI
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![BU of 8gui by Molmil](/molmil-images/mine/8gui) | Bre1-nucleosome complex (Model I) | 分子名称: | DNA (147-mer), E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, ... | 著者 | Onishi, S, Hamada, K, Sato, K, Nishizawa, T, Nureki, O, Ogata, K, Sengoku, T. | 登録日 | 2022-09-12 | 公開日 | 2023-09-20 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | 主引用文献 | Structure of the human Bre1 complex bound to the nucleosome. Nat Commun, 15, 2024
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8JJS
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![BU of 8jjs by Molmil](/molmil-images/mine/8jjs) | Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor AP10343 | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, MAA-ILE-SAR-SAR-7T2-SAR-IAE-LEU-MEA-MLE-7TK, ... | 著者 | Irie, M, Fukami, T.A, Tanada, M, Ohta, A, Torizawa, T. | 登録日 | 2023-05-31 | 公開日 | 2023-07-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.534 Å) | 主引用文献 | Development of Orally Bioavailable Peptides Targeting an Intracellular Protein: From a Hit to a Clinical KRAS Inhibitor. J.Am.Chem.Soc., 145, 2023
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3X3C
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![BU of 3x3c by Molmil](/molmil-images/mine/3x3c) | Crystal structure of the light-driven sodium pump KR2 in neutral state | 分子名称: | OLEIC ACID, RETINAL, Sodium pumping rhodopsin | 著者 | Kato, H.E, Inoue, K, Abe-Yoshizumi, R, Kato, Y, Ono, H, Konno, M, Ishizuka, T, Hoque, M.R, Hososhima, S, Kunitomo, H, Ito, J, Yoshizawa, S, Yamashita, K, Takemoto, M, Nishizawa, T, Taniguchi, R, Kogure, K, Maturana, A.D, Iino, Y, Yawo, H, Ishitani, R, Kandori, H, Nureki, O. | 登録日 | 2015-01-18 | 公開日 | 2015-04-08 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for Na(+) transport mechanism by a light-driven Na(+) pump Nature, 521, 2015
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3X3B
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![BU of 3x3b by Molmil](/molmil-images/mine/3x3b) | Crystal structure of the light-driven sodium pump KR2 in acidic state | 分子名称: | DI(HYDROXYETHYL)ETHER, OLEIC ACID, RETINAL, ... | 著者 | Kato, H.E, Inoue, K, Abe-Yoshizumi, R, Kato, Y, Ono, H, Konno, M, Ishizuka, T, Hoque, M.R, Hososhima, S, Kunitomo, H, Ito, J, Yoshizawa, S, Yamashita, K, Takemoto, M, Nishizawa, T, Taniguchi, R, Kogure, K, Maturana, A.D, Iino, Y, Yawo, H, Ishitani, R, Kandori, H, Nureki, O. | 登録日 | 2015-01-18 | 公開日 | 2015-04-08 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for Na(+) transport mechanism by a light-driven Na(+) pump Nature, 521, 2015
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6LGP
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![BU of 6lgp by Molmil](/molmil-images/mine/6lgp) | cryo-EM structure of TRPV3 in lipid nanodisc | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, DIUNDECYL PHOSPHATIDYL CHOLINE, Transient receptor potential cation channel subfamily V member 3 | 著者 | Shimada, H, Kusakizako, T, Nishizawa, T, Nureki, O. | 登録日 | 2019-12-05 | 公開日 | 2020-06-24 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | The structure of lipid nanodisc-reconstituted TRPV3 reveals the gating mechanism. Nat.Struct.Mol.Biol., 27, 2020
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2N92
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![BU of 2n92 by Molmil](/molmil-images/mine/2n92) | Solution structure of cecropin P1 with LPS | 分子名称: | Cecropin-P1 | 著者 | Baek, M, Kamiya, M, Kushibiki, T, Nakazumi, T, Tomisawa, S, Abe, C, Kumaki, Y, Kikukawa, T, Demura, M, Kawano, K, Aizawa, T. | 登録日 | 2015-11-04 | 公開日 | 2016-11-09 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Lipopolysaccharide bound structure of antimicrobial peptide cecropin P1 by NMR spectroscopy To be Published
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2RRF
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![BU of 2rrf by Molmil](/molmil-images/mine/2rrf) | The solution structure of the C-terminal region of Zinc finger FYVE domain-containing protein 21 | 分子名称: | Zinc finger FYVE domain-containing protein 21 | 著者 | Koshiba, S, Tomizawa, T, Hayashi, F, Tochio, N, Harada, T, Watanabe, S, Kigawa, T, Yokoyama, S. | 登録日 | 2010-08-03 | 公開日 | 2011-08-03 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | ZF21 protein, a regulator of the disassembly of focal adhesions and cancer metastasis, contains a novel noncanonical pleckstrin homology domain J.Biol.Chem., 286, 2011
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8WJ2
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![BU of 8wj2 by Molmil](/molmil-images/mine/8wj2) | cryo-EM structure of human haemoglobin in deoxy form | 分子名称: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Takahashi, K, Lee, Y, Fago, A, Bautista, N.M, Kawamoto, A, Kurisu, G, Storz, J, Nishizawa, T, Tame, J.R.H. | 登録日 | 2023-09-25 | 公開日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (2.35 Å) | 主引用文献 | The unique allosteric property of crocodilian haemoglobin elucidated by cryo-EM. Nat Commun, 15, 2024
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8WIX
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![BU of 8wix by Molmil](/molmil-images/mine/8wix) | cryo-EM structure of alligator haemoglobin in carbonmonoxy form | 分子名称: | CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | 著者 | Takahashi, K, Lee, Y, Fago, A, Bautista, N.M, Kawamoto, A, Kurisu, G, Storz, J, Nishizawa, T, Tame, J.R.H. | 登録日 | 2023-09-25 | 公開日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (2.29 Å) | 主引用文献 | The unique allosteric property of crocodilian haemoglobin elucidated by cryo-EM. Nat Commun, 15, 2024
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8WJ1
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![BU of 8wj1 by Molmil](/molmil-images/mine/8wj1) | cryo-EM structure of human haemoglobin in oxy form | 分子名称: | Hemoglobin subunit alpha, Hemoglobin subunit beta, OXYGEN MOLECULE, ... | 著者 | Takahashi, K, Lee, Y, Fago, A, Bautista, N.M, Kawamoto, A, Kurisu, G, Storz, J, Nishizawa, T, Tame, J.R.H. | 登録日 | 2023-09-25 | 公開日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (2.27 Å) | 主引用文献 | The unique allosteric property of crocodilian haemoglobin elucidated by cryo-EM. Nat Commun, 15, 2024
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8WIY
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![BU of 8wiy by Molmil](/molmil-images/mine/8wiy) | cryo-EM structure of alligator haemoglobin in oxy form | 分子名称: | Hemoglobin subunit alpha, Hemoglobin subunit beta, OXYGEN MOLECULE, ... | 著者 | Takahashi, K, Lee, Y, Fago, A, Bautista, N.M, Kawamoto, A, Kurisu, G, Storz, J, Nishizawa, T, Tame, J.R.H. | 登録日 | 2023-09-25 | 公開日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (2.31 Å) | 主引用文献 | The unique allosteric property of crocodilian haemoglobin elucidated by cryo-EM. Nat Commun, 15, 2024
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8WIZ
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![BU of 8wiz by Molmil](/molmil-images/mine/8wiz) | cryo-EM structure of alligator haemoglobin in deoxy form | 分子名称: | BICARBONATE ION, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | 著者 | Takahashi, K, Lee, Y, Fago, A, Bautista, N.M, Kawamoto, A, Kurisu, G, Storz, J, Nishizawa, T, Tame, J.R.H. | 登録日 | 2023-09-25 | 公開日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | The unique allosteric property of crocodilian haemoglobin elucidated by cryo-EM. Nat Commun, 15, 2024
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8WJ0
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![BU of 8wj0 by Molmil](/molmil-images/mine/8wj0) | cryo-EM structure of human haemoglobin in carbonmonoxy form | 分子名称: | CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | 著者 | Takahashi, K, Lee, Y, Fago, A, Bautista, N.M, Kawamoto, A, Kurisu, G, Storz, J, Nishizawa, T, Tame, J.R.H. | 登録日 | 2023-09-25 | 公開日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (2.24 Å) | 主引用文献 | The unique allosteric property of crocodilian haemoglobin elucidated by cryo-EM. Nat Commun, 15, 2024
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2MDB
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![BU of 2mdb by Molmil](/molmil-images/mine/2mdb) | Tachyplesin I in the presence of lipopolysaccharide | 分子名称: | Tachyplesin-1 | 著者 | Kushibiki, T, Kamiya, M, Aizawa, T, Kumaki, Y, Kikukawa, T, Mizuguchi, M, Demura, M, Kawabata, S.I, Kawano, K. | 登録日 | 2013-09-09 | 公開日 | 2014-02-19 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Interaction between tachyplesin I, an antimicrobial peptide derived from horseshoe crab, and lipopolysaccharide. Biochim.Biophys.Acta, 1844, 2014
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