4Z9I
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![BU of 4z9i by Molmil](/molmil-images/mine/4z9i) | Asp-TarS from E. coli | 分子名称: | ASPARTIC ACID, Methyl-accepting chemotaxis protein II | 著者 | Mise, T. | 登録日 | 2015-04-10 | 公開日 | 2016-07-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Structural Analysis of the Ligand-Binding Domain of the Aspartate Receptor Tar from Escherichia coli Biochemistry, 55, 2016
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4Z9H
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![BU of 4z9h by Molmil](/molmil-images/mine/4z9h) | Asp-Tar from E. coli | 分子名称: | ASPARTIC ACID, Methyl-accepting chemotaxis protein II | 著者 | Mise, T. | 登録日 | 2015-04-10 | 公開日 | 2016-07-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.452 Å) | 主引用文献 | Structural Analysis of the Ligand-Binding Domain of the Aspartate Receptor Tar from Escherichia coli Biochemistry, 55, 2016
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4Z9J
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![BU of 4z9j by Molmil](/molmil-images/mine/4z9j) | Apo-Tar from E. coli | 分子名称: | Methyl-accepting chemotaxis protein II | 著者 | Mise, T. | 登録日 | 2015-04-10 | 公開日 | 2016-07-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structural Analysis of the Ligand-Binding Domain of the Aspartate Receptor Tar from Escherichia coli Biochemistry, 55, 2016
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3HRX
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![BU of 3hrx by Molmil](/molmil-images/mine/3hrx) | |
2K1Q
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![BU of 2k1q by Molmil](/molmil-images/mine/2k1q) | NMR structure of hepatitis c virus ns3 serine protease complexed with the non-covalently bound phenethylamide inhibitor | 分子名称: | NS3 PROTEASE, PHENETHYLAMIDE, ZINC ION | 著者 | Eliseo, T, Gallo, M, Pennestri, M, Bazzo, R, Cicero, D.O. | 登録日 | 2008-03-13 | 公開日 | 2009-02-03 | 最終更新日 | 2023-11-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Binding of a noncovalent inhibitor exploiting the S' region stabilizes the hepatitis C virus NS3 protease conformation in the absence of cofactor. J.Mol.Biol., 385, 2009
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2JN3
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![BU of 2jn3 by Molmil](/molmil-images/mine/2jn3) | NMR structure of cl-BABP complexed to chenodeoxycholic acid | 分子名称: | CHENODEOXYCHOLIC ACID, Fatty acid-binding protein, liver | 著者 | Eliseo, T, Ragona, L, Catalano, M, Assfalf, M, Paci, M, Zetta, L, Molinari, H, Cicero, D.O. | 登録日 | 2006-12-22 | 公開日 | 2007-07-03 | 最終更新日 | 2023-12-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and dynamic determinants of ligand binding in the ternary complex of chicken liver bile acid binding protein with two bile salts revealed by NMR Biochemistry, 46, 2007
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5JHQ
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![BU of 5jhq by Molmil](/molmil-images/mine/5jhq) | |
1NXN
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![BU of 1nxn by Molmil](/molmil-images/mine/1nxn) | SOLUTION STRUCTURE OF CONTRYPHAN-VN | 分子名称: | CONTRYPHAN-VN, MAJOR FORM (CIS CONFORMER) | 著者 | Eliseo, T, Cicero, D.O, Polticelli, F, Schinina, M.E, Massilia, G.R, Paci, M, Ascenzi, P. | 登録日 | 2003-02-11 | 公開日 | 2003-03-04 | 最終更新日 | 2020-06-24 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the cyclic peptide contryphan-Vn, a Ca2+-dependent K+ channel modulator Biopolymers, 74, 2004
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1ZH1
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![BU of 1zh1 by Molmil](/molmil-images/mine/1zh1) | |
1ZZF
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![BU of 1zzf by Molmil](/molmil-images/mine/1zzf) | |
8HLB
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![BU of 8hlb by Molmil](/molmil-images/mine/8hlb) | Cryo-EM structure of biparatopic antibody Bp109-92 in complex with TNFR2 | 分子名称: | TR109 heavy chain, TR109 light chain, TR92 heavy chain, ... | 著者 | Akiba, H, Fujita, J, Ise, T, Nishiyama, K, Miyata, T, Kato, T, Namba, K, Ohno, H, Kamada, H, Nagata, S, Tsumoto, K. | 登録日 | 2022-11-29 | 公開日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | 主引用文献 | Development of a 1:1-binding biparatopic anti-TNFR2 antagonist by reducing signaling activity through epitope selection. Commun Biol, 6, 2023
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6YQN
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![BU of 6yqn by Molmil](/molmil-images/mine/6yqn) | Crystal structure of the first bromodomain of human BRD4 in complex with the dual inhibitor TW9 | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ~{N}-(2-aminophenyl)-4-[2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]t rideca-2(6),4,7,10,12-pentaen-9-yl]ethanoylamino]benzamide | 著者 | Joerger, A.C, Balourdas, D.I, Weiser, T, Chatterjee, D, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2020-04-17 | 公開日 | 2020-05-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | Characterization of a dual BET/HDAC inhibitor for treatment of pancreatic ductal adenocarcinoma. Int.J.Cancer, 147, 2020
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6YQP
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![BU of 6yqp by Molmil](/molmil-images/mine/6yqp) | Crystal structure of the first bromodomain of human BRD4 in complex with the dual inhibitor TW22 | 分子名称: | (~{E})-3-[4-[[2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6 ),4,7,10,12-pentaen-9-yl]ethanoylamino]methyl]phenyl]-~{N}-oxidanyl-prop-2-enamide, 1,2-ETHANEDIOL, Bromodomain-containing protein 4 | 著者 | Joerger, A.C, Balourdas, D.I, Weiser, T, Chatterjee, D, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2020-04-17 | 公開日 | 2020-05-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Characterization of a dual BET/HDAC inhibitor for treatment of pancreatic ductal adenocarcinoma. Int.J.Cancer, 147, 2020
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6YQO
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![BU of 6yqo by Molmil](/molmil-images/mine/6yqo) | Crystal structure of the first bromodomain of human BRD4 in complex with the dual inhibitor TW12 | 分子名称: | (S)-N1-(4-(2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamido)phenyl)-N8-hydroxyoctanediamide, 1,2-ETHANEDIOL, Bromodomain-containing protein 4 | 著者 | Joerger, A.C, Balourdas, D.I, Weiser, T, Chatterjee, D, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2020-04-17 | 公開日 | 2020-05-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | 主引用文献 | Characterization of a dual BET/HDAC inhibitor for treatment of pancreatic ductal adenocarcinoma. Int.J.Cancer, 147, 2020
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1YO8
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![BU of 1yo8 by Molmil](/molmil-images/mine/1yo8) | Structure of the C-terminal domain of human thrombospondin-2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Carlson, C.B, Bernstein, D.A, Annis, D.S, Misenheimer, T.M, Hannah, B.A, Mosher, D.F, Keck, J.L. | 登録日 | 2005-01-26 | 公開日 | 2005-09-27 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of the calcium-rich signature domain of human thrombospondin-2 Nat.Struct.Mol.Biol., 12, 2005
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2K6L
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![BU of 2k6l by Molmil](/molmil-images/mine/2k6l) | The solution structure of XACb0070 from Xanthonomas axonopodis pv citri reveals this new protein is a member of the RHH family of transcriptional repressors | 分子名称: | Putative uncharacterized protein | 著者 | Gallo, M, Cicero, D.O, Amata, I, Eliseo, T, Paci, M, Spisni, A, Ferrari, E, Pertinhez, T.A, Farah, C.S. | 登録日 | 2008-07-11 | 公開日 | 2009-06-16 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | The solution structure reveals that XACb0070 from the plant pathogen Xanthomonas citri belongs to the RHH superfamily of bacterial DNA-binding proteins To be Published
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2MNQ
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![BU of 2mnq by Molmil](/molmil-images/mine/2mnq) | 1H, 13C, and 15N Chemical Shift Assignments for Thymosin alpha 1 | 分子名称: | THYMOSIN ALPHA-1 | 著者 | Nepravishta, R, Mandaliti, W, Eliseo, T, Sinibaldi Vallebona, P, Pica, F, Garaci, E, Paci, M. | 登録日 | 2014-04-09 | 公開日 | 2015-03-04 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Thymosin alpha 1 inserts N terminus into model membranes assuming a helical conformation. Expert Opin Biol Ther, 15 Suppl 1, 2015
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2OII
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![BU of 2oii by Molmil](/molmil-images/mine/2oii) | Structure of EMILIN-1 C1q-like domain | 分子名称: | EMILIN-1 | 著者 | Verdone, G, Colebrooke, S.A, Corazza, A, Cicero, D.O, Eliseo, T, Viglino, P, Campbell, I.D, Colombatti, A, Esposito, G. | 登録日 | 2007-01-11 | 公開日 | 2008-01-22 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | The solution structure of the C-terminal domain of EMILIN-1 To be Published
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2M2B
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![BU of 2m2b by Molmil](/molmil-images/mine/2m2b) | NMR structure of the RRM2 domain of the protein RBM10 from Homo sapiens | 分子名称: | RNA-binding protein 10 | 著者 | Serrano, P, Geralt, M, Dutta, S.K, Wuthrich, K, Wrobel, R.L, Makino, S, Misenhiemer, T.M, Markley, J.L, Fox, B.G, Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL), Mitochondrial Protein Partnership (MPP) | 登録日 | 2012-12-17 | 公開日 | 2013-01-16 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of the RRM2 domain of the protein RBM10 from Homo sapiens To be Published
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2KA3
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![BU of 2ka3 by Molmil](/molmil-images/mine/2ka3) | Structure of EMILIN-1 C1Q-like domain | 分子名称: | EMILIN-1 | 著者 | Verdone, G, Corazza, A, Colebrooke, S.A, Cicero, D.O, Eliseo, T, Boyd, J, Doliana, R, Fogolari, F, Viglino, P, Colombatti, A, Campbell, I.D, Esposito, G. | 登録日 | 2008-10-30 | 公開日 | 2008-11-25 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR-based homology model for the solution structure of the C-terminal globular domain of EMILIN1 J.Biomol.Nmr, 43, 2009
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6XM1
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6XMD
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6FE6
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![BU of 6fe6 by Molmil](/molmil-images/mine/6fe6) | Solution structure of a last generation P2-P4 macrocyclic inhibitor | 分子名称: | (3aR,7S,10S,12R,24aR)-7-cyclopentyl-N-{(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl}-5,8-dioxo-1,2,3,3a,5,6,7,8,11,12,20,21,22,23,24,24a-hexadecahydro-10H-9,12-methanocyclopenta[18,19][1,10,3,6]dioxadiazacyclononadecino[12,11-b]quinoline-10-carboxamide, Non-structural 3 protease, ZINC ION | 著者 | Gallo, M, Eliseo, T, Cicero, D.O. | 登録日 | 2017-12-29 | 公開日 | 2019-01-30 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a last generation macrocyclic inhibitor. Hepatitis C virus NS3 protease complex: when S prime region occupancy is not enough to stabilize the protein conformation in the absence of NS4A. To Be Published
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1BY1
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![BU of 1by1 by Molmil](/molmil-images/mine/1by1) | DBL homology domain from beta-PIX | 分子名称: | PROTEIN (PIX) | 著者 | Aghazadeh, B, Zhu, K, Kubiseski, T.J, Liu, G.A, Pawson, T, Zheng, Y, Rosen, M.K. | 登録日 | 1998-10-22 | 公開日 | 1999-10-24 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and Mutagenesis of the Dbl Homology Domain Nat.Struct.Biol., 5, 1998
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1R8P
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![BU of 1r8p by Molmil](/molmil-images/mine/1r8p) | |