1C5H
| HYDROGEN BONDING AND CATALYSIS: AN UNEXPECTED EXPLANATION FOR HOW A SINGLE AMINO ACID SUBSTITUTION CAN CHANGE THE PH OPTIMUM OF A GLYCOSIDASE | Descriptor: | ENDO-1,4-BETA-XYLANASE | Authors: | Joshi, M.D, Sidhu, G, Pot, I, Brayer, G.D, Withers, S.G, Mcintosh, L.P. | Deposit date: | 1999-11-24 | Release date: | 2000-05-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Hydrogen bonding and catalysis: a novel explanation for how a single amino acid substitution can change the pH optimum of a glycosidase. J.Mol.Biol., 299, 2000
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1C5B
| DECARBOXYLASE CATALYTIC ANTIBODY 21D8 UNLIGANDED FORM | Descriptor: | CHIMERIC DECARBOXYLASE ANTIBODY 21D8 | Authors: | Hotta, K, Wilson, I.A. | Deposit date: | 1999-11-08 | Release date: | 2000-10-11 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Catalysis of decarboxylation by a preorganized heterogeneous microenvironment: crystal structures of abzyme 21D8. J.Mol.Biol., 302, 2000
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1C5I
| HYDROGEN BONDING AND CATALYSIS: AN UNEXPECTED EXPLANATION FOR HOW A SINGLE AMINO ACID SUBSTITUTION CAN CHANGE THE PH OPTIMUM OF A GLYCOSIDASE | Descriptor: | ENDO-1,4-BETA-XYLANASE, beta-D-xylopyranose-(1-4)-1,5-anhydro-2-deoxy-2-fluoro-D-xylitol | Authors: | Joshi, M.D, Sidhu, G, Pot, I, Brayer, G.D, Withers, S.G, Mcintosh, L.P. | Deposit date: | 1999-11-24 | Release date: | 2000-05-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Hydrogen bonding and catalysis: a novel explanation for how a single amino acid substitution can change the pH optimum of a glycosidase. J.Mol.Biol., 299, 2000
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4K6A
| Revised Crystal Structure of apo-form of Triosephosphate Isomerase (tpiA) from Escherichia coli at 1.8 Angstrom Resolution. | Descriptor: | SODIUM ION, Triosephosphate isomerase | Authors: | Minasov, G, Kuhn, M, Halavaty, A, Shuvalova, L, Dubrovska, I, Winsor, J, Grimshaw, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-04-15 | Release date: | 2013-05-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation. PLoS ONE, 9, 2014
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1C5C
| DECARBOXYLASE CATALYTIC ANTIBODY 21D8-HAPTEN COMPLEX | Descriptor: | 2-ACETYLAMINO-NAPTHALENE-1,5-DISULFONIC ACID, CHIMERIC DECARBOXYLASE ANTIBODY 21D8, GLYCEROL | Authors: | Hotta, K, Wilson, I.A. | Deposit date: | 1999-11-09 | Release date: | 2000-10-11 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Catalysis of decarboxylation by a preorganized heterogeneous microenvironment: crystal structures of abzyme 21D8. J.Mol.Biol., 302, 2000
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7DEQ
| Lysozyme-sugar complex in D2O | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Lysozyme C, ... | Authors: | Tanaka, I, Chatake, T. | Deposit date: | 2020-11-04 | Release date: | 2021-03-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.03 Å) | Cite: | Recent structural insights into the mechanism of lysozyme hydrolysis. Acta Crystallogr D Struct Biol, 77, 2021
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4B22
| Unprecedented sculpting of DNA at abasic sites by DNA glycosylase homolog Mag2 | Descriptor: | 5'-D(*CP*GP*AP*TP*GP*GP*GP*TP*AP*GP*CP)-3', 5'-D(*GP*CP*TP*AP*CP*(3DR)P*CP*AP*TP*CP*GP)-3', MAG2, ... | Authors: | Dalhus, B, Nilsen, L, Korvald, H, Huffman, J, Forstrom, R.J, McMurray, C.T, Alseth, I, Tainer, J.A, Bjoras, M. | Deposit date: | 2012-07-12 | Release date: | 2013-01-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Sculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2. Structure, 21, 2013
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4B93
| Complex of Vamp7 cytoplasmic domain with 2nd ankyrin repeat domain of Varp | Descriptor: | ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27, VESICLE-ASSOCIATED MEMBRANE PROTEIN 7 | Authors: | Schaefer, I.B, Owen, D.J, Luzio, J.P, Evans, P.R. | Deposit date: | 2012-08-31 | Release date: | 2012-10-31 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Binding of Varp to Vamp7 Traps Vamp7 in a Closed, Fusogenically Inactive Conformation. Nat.Struct.Mol.Biol., 19, 2012
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1UZ9
| Crystallographic and solution studies of N-lithocholyl insulin: a new generation of prolonged-acting insulins. | Descriptor: | (2S)-2-AMINO-6-({(4R)-4-[(10R,13S)-10,13-DIMETHYL-3-OXOHEXADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-17-YL]PENTANOYL}AMINO)HEXANOIC ACID, CHLORIDE ION, INSULIN, ... | Authors: | Whittingham, J.L, Jonassen, I, Havelund, S, Roberts, S.M, Dodson, E.J, Verma, C.S, Wilkinson, A.J, Dodson, G.G. | Deposit date: | 2004-03-08 | Release date: | 2005-03-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystallographic and Solution Studies of N-Lithocholyl Insulin: A New Generation of Prolonged-Acting Human Insulins Biochemistry, 43, 2004
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1UT9
| Structural Basis for the Exocellulase Activity of the Cellobiohydrolase CbhA from C. thermocellum | Descriptor: | CELLULOSE 1,4-BETA-CELLOBIOSIDASE | Authors: | Schubot, F.D, Kataeva, I.A, Chang, J, Shah, A.K, Ljungdahl, L.G, Rose, J.P, Wang, B.C. | Deposit date: | 2003-12-04 | Release date: | 2004-02-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for the exocellulase activity of the cellobiohydrolase CbhA from Clostridium thermocellum. Biochemistry, 43, 2004
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7DER
| Lysozyme alone in H2O | Descriptor: | CHLORIDE ION, Lysozyme C, SODIUM ION | Authors: | Tanaka, I, Chatake, T. | Deposit date: | 2020-11-04 | Release date: | 2021-03-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.03 Å) | Cite: | Recent structural insights into the mechanism of lysozyme hydrolysis. Acta Crystallogr D Struct Biol, 77, 2021
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1D8V
| THE RESTRAINED AND MINIMIZED AVERAGE NMR STRUCTURE OF MAP30. | Descriptor: | ANTI-HIV AND ANTI-TUMOR PROTEIN MAP30 | Authors: | Wang, Y.-X, Neamati, N, Jacob, J, Palmer, I, Stahl, S.J. | Deposit date: | 1999-10-26 | Release date: | 1999-11-19 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of anti-HIV-1 and anti-tumor protein MAP30: structural insights into its multiple functions. Cell(Cambridge,Mass.), 99, 1999
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1V9Z
| Crystal Structure of the heme PAS sensor domain of Ec DOS (Ferrous Form) | Descriptor: | Heme pas sensor protein, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Kurokawa, H, Lee, D.S, Watanabe, M, Sagami, I, Mikami, B, Raman, C.S, Shimizu, T. | Deposit date: | 2004-02-04 | Release date: | 2004-05-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A redox-controlled molecular switch revealed by the crystal structure of a bacterial heme PAS sensor. J.Biol.Chem., 279, 2004
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4JA2
| Structural basis of a rationally rewired protein-protein interface (RR468mutant V13P, L14I, I17M and N21V) | Descriptor: | ACETATE ION, MAGNESIUM ION, Response regulator, ... | Authors: | Podgornaia, A.I, Casino, P, Marina, A, Laub, M.T. | Deposit date: | 2013-02-18 | Release date: | 2013-09-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling Structure, 21, 2013
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1UU5
| X-RAY CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMICOLA GRISEA CEL12A SOAKED WITH CELLOTETRAOSE | Descriptor: | ACETATE ION, ENDO-BETA-1,4-GLUCANASE, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | Authors: | Berglund, G.I, Shaw, A, Stahlberg, J, Kenne, L, Driguez, T.H, Mitchinson, C, Sandgren, M. | Deposit date: | 2003-12-15 | Release date: | 2004-09-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Crystal Complex Structures Reveal How Substrate is Bound in the -4 to the +2 Binding Sites of Humicola Grisea Cel12A J.Mol.Biol., 342, 2004
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4JY4
| Crystal structure of human Fab PGT121, a broadly reactive and potent HIV-1 neutralizing antibody | Descriptor: | GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PGT121 heavy chain, ... | Authors: | Julien, J.-P, Diwanji, D.C, Burton, D.R, Wilson, I.A. | Deposit date: | 2013-03-29 | Release date: | 2013-05-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans. Plos Pathog., 9, 2013
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1UOF
| Deacetoxycephalosporin C synthase complexed with Penicillin G | Descriptor: | DEACETOXYCEPHALOSPORIN C SYNTHETASE, FE (II) ION, PENICILLIN G | Authors: | Valegard, K, Terwisscha Van scheltinga, A.C, Dubus, A, Oster, L.M, Rhangino, G, Hajdu, J, Andersson, I. | Deposit date: | 2003-09-16 | Release date: | 2004-01-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The Structural Basis of Cephalosporin Formation in a Mononuclear Ferrous Enzyme Nat.Struct.Mol.Biol., 11, 2004
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3K21
| Crystal Structure of carboxy-terminus of PFC0420w. | Descriptor: | ACETATE ION, CALCIUM ION, Calcium-dependent protein kinase 3, ... | Authors: | Wernimont, A.K, Hutchinson, A, Artz, J.D, Mackenzie, F, Cossar, D, Kozieradzki, I, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Hui, R, Amani, M, Structural Genomics Consortium (SGC) | Deposit date: | 2009-09-29 | Release date: | 2010-01-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Structures of parasitic CDPK domains point to a common mechanism of activation. Proteins, 79, 2011
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4JM2
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7DUA
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7DU9
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1V9G
| Neutron Crystallographic analysis of the Z-DNA hexamer CGCGCG | Descriptor: | 5'-D(*CP*GP*CP*GP*CP*G)-3', N,N'-BIS(3-AMMONIOPROPYL)BUTANE-1,4-DIAMINIUM | Authors: | Chatake, T, Tanaka, I, Niimura, N. | Deposit date: | 2004-01-26 | Release date: | 2005-01-26 | Last modified: | 2023-10-25 | Method: | NEUTRON DIFFRACTION (1.8 Å) | Cite: | The hydration structure of a Z-DNA hexameric duplex determined by a neutron diffraction technique. Acta Crystallogr.,Sect.D, 61, 2005
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1ELR
| Crystal structure of the TPR2A domain of HOP in complex with the HSP90 peptide MEEVD | Descriptor: | HSP90-PEPTIDE MEEVD, NICKEL (II) ION, TPR2A-DOMAIN OF HOP | Authors: | Scheufler, C, Brinker, A, Hartl, F.U, Moarefi, I. | Deposit date: | 2000-03-14 | Release date: | 2000-04-26 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine. Cell(Cambridge,Mass.), 101, 2000
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1EQ9
| CRYSTAL STRUCTURE OF FIRE ANT CHYMOTRYPSIN COMPLEXED TO PMSF | Descriptor: | CHYMOTRYPSIN, phenylmethanesulfonic acid | Authors: | Botos, I, Meyer, E, Nguyen, M.H, Swanson, S.M, Meyer, E.F. | Deposit date: | 2000-04-03 | Release date: | 2000-10-03 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The structure of an insect chymotrypsin. J.Mol.Biol., 298, 2000
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1UU4
| X-RAY CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMICOLA GRISEA CEL12A IN COMPLEX WITH CELLOBIOSE | Descriptor: | ENDO-BETA-1,4-GLUCANASE, TETRAETHYLENE GLYCOL, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | Authors: | Berglund, G.I, Shaw, A, Stahlberg, J, Kenne, L, Driguez, T.H, Mitchinson, C, Sandgren, M. | Deposit date: | 2003-12-15 | Release date: | 2004-09-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Crystal Complex Structures Reveal How Substrate is Bound in the -4 to the +2 Binding Sites of Humicola Grisea Cel12A J.Mol.Biol., 342, 2004
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