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PDB: 17965 件

1M5C
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X-RAY STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH Br-HIBO AT 1.65 A RESOLUTION
分子名称: (S)-2-AMINO-3-(4-BROMO-3-HYDROXY-ISOXAZOL-5-YL)PROPIONIC ACID, Glutamate receptor 2
著者Hogner, A, Kastrup, J.S, Jin, R, Liljefors, T, Mayer, M.L, Egebjerg, J, Larsen, I.K, Gouaux, E.
登録日2002-07-09
公開日2002-09-18
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural Basis for AMPA Receptor Activation and Ligand Selectivity: Crystal Structures of Five Agonist Complexes with the GluR2 Ligand-binding Core
J.Mol.Biol., 322, 2002
5XD9
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Crystal structure analysis of 3,6-anhydro-L-galactonate cycloisomerase
分子名称: 3,6-anhydro-alpha-L-galactonate cycloisomerase, MAGNESIUM ION
著者Lee, S, Choi, I.-G, Kim, H.-Y.
登録日2017-03-27
公開日2017-09-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure analysis of 3,6-anhydro-l-galactonate cycloisomerase suggests emergence of novel substrate specificity in the enolase superfamily
Biochem. Biophys. Res. Commun., 491, 2017
3KMM
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Structure of human LCK kinase with a small molecule inhibitor
分子名称: 3-(2,6-dichlorophenyl)-7-({4-[2-(diethylamino)ethoxy]phenyl}amino)-1-methyl-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one, Proto-oncogene tyrosine-protein kinase LCK, SULFATE ION
著者Graves, B.J, Surgenor, A, Harris, W, Smith, I, Orchard, S, Flotow, H, Murray, E.
登録日2009-11-10
公開日2010-12-08
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of human LCK kinase with a small molecule inhibitor
To be Published
2OBU
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Solution structure of GIP in TFE/water
分子名称: Gastric inhibitory polypeptide
著者Alana, I, Malthouse, J.P.G, O'Harte, F.P.M, Hewage, C.M.
登録日2006-12-20
公開日2007-06-05
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献The bioactive conformation of glucose-dependent insulinotropic polypeptide by NMR and CD spectroscopy
Proteins, 68, 2007
6FQG
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GluA2(flop) G724C ligand binding core dimer bound to L-Glutamate (Form A) at 2.34 Angstrom resolution
分子名称: GLUTAMIC ACID, Glutamate receptor 2
著者Coombs, I.D, Soto, D, Gold, M.G, Farrant, M.F, Cull-Candy, S.G.
登録日2018-02-14
公開日2019-03-13
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.34139085 Å)
主引用文献X-ray structure of GluA2 flop G724C ligand binding core dimer bound to glutamate at 2.32 Angstroms resolution
To Be Published
2EOT
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SOLUTION STRUCTURE OF EOTAXIN, AN ENSEMBLE OF 32 NMR SOLUTION STRUCTURES
分子名称: EOTAXIN
著者Crump, M.P, Rajarathnam, K, Kim, K.-S, Clark-Lewis, I, Sykes, B.D.
登録日1998-06-29
公開日1998-11-11
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammation.
J.Biol.Chem., 273, 1998
1W5Y
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HIV-1 protease in complex with fluoro substituted diol-based C2- symmetric inhibitor
分子名称: (2R,3R,4R,5R)-2,5-BIS[(2,5-DIFLUOROBENZYL)OXY]-3,4-DIHYDROXY-N,N'-BIS[(1S,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL]HEXANEDIAMIDE, POL POLYPROTEIN
著者Lindberg, J, Pyring, D, Loewgren, S, Rosenquist, A, Zuccarello, G, Kvarnstroem, I, Zhang, H, Vrang, L, Claesson, B, Hallberg, A, Samuelsson, B, Unge, T.
登録日2004-08-10
公開日2004-10-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Symmetric Fluoro-Substituted Diol-Based HIV Protease Inhibitors. Ortho-Fluorinated and Meta-Fluorinated P1/P1'-Benzyloxy Side Groups Significantly Improve the Antiviral Activity and Preserve Binding Efficacy
Eur.J.Biochem., 271, 2004
1M9D
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X-ray crystal structure of Cyclophilin A/HIV-1 CA N-terminal domain (1-146) O-type chimera Complex.
分子名称: Cyclophilin A, HIV-1 Capsid
著者Howard, B.R, Vajdos, F.F, Li, S, Sundquist, W.I, Hill, C.P.
登録日2002-07-28
公開日2003-05-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into the catalytic mechanism of cyclophilin A
Nat.Struct.Biol., 10, 2003
5T04
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STRUCTURE OF CONSTITUTIVELY ACTIVE NEUROTENSIN RECEPTOR
分子名称: 3,3',3''-phosphanetriyltripropanoic acid, ARG-ARG-PRO-TYR-ILE-LEU, DI(HYDROXYETHYL)ETHER, ...
著者Krumm, B, Botos, I, Grisshammer, R.
登録日2016-08-15
公開日2016-12-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure and dynamics of a constitutively active neurotensin receptor.
Sci Rep, 6, 2016
1W9C
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Proteolytic fragment of CRM1 spanning six C-terminal HEAT repeats
分子名称: CRM1 PROTEIN
著者Petosa, C, Schoehn, G, Askjaer, P, Bauer, U, Moulin, M, Steuerwald, U, Soler-Lopez, M, Baudin, F, Mattaj, I.W, Muller, C.W.
登録日2004-10-08
公開日2004-12-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Architecture of Crm1-Exportin 1 Suggests How Cooperativity is Achieved During Formation of a Nuclear Export Complex
Mol.Cell, 16, 2004
5T38
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Crystal Structure of the N-terminal domain of EvdMO1 with SAH bound
分子名称: EvdMO1, S-ADENOSYL-L-HOMOCYSTEINE
著者McCulloch, K.M, Berndt, S, Yamakawa, I, Chen, Q, Loukachevitch, L.V, Starbird, C, Perry, N.A, Iverson, T.M.
登録日2016-08-25
公開日2017-09-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.1502 Å)
主引用文献The Structure of the Bifunctional Everninomicin Biosynthetic Enzyme EvdMO1 Suggests Independent Activity of the Fused Methyltransferase-Oxidase Domains.
Biochemistry, 57, 2018
6FSG
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Crystal structure of oxidised Flavodoxin 1 from Bacillus cereus (1.27 A resolution)
分子名称: FLAVIN MONONUCLEOTIDE, Flavodoxin, SULFATE ION, ...
著者Gudim, I, Lofstad, M, Hersleth, H.-P.
登録日2018-02-19
公開日2018-07-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献High-resolution crystal structures reveal a mixture of conformers of the Gly61-Asp62 peptide bond in an oxidized flavodoxin from Bacillus cereus.
Protein Sci., 27, 2018
2O3X
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Crystal Structure of the Prokaryotic Ribosomal Decoding Site Complexed with Paromamine Derivative NB30
分子名称: (1R,2R,3S,4R,6S)-4,6-DIAMINO-2-[(5-AMINO-5-DEOXY-BETA-D-RIBOFURANOSYL)OXY]-3-HYDROXYCYCLOHEXYL 2-AMINO-2-DEOXY-ALPHA-D-GLUCOPYRANOSIDE, RNA (5'-R(*UP*UP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3')
著者Kondo, J, Hainrichson, M, Nudelman, I, Shallom-Shezifi, D, Baasov, T, Westhof, E.
登録日2006-12-02
公開日2007-11-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Differential Selectivity of Natural and Synthetic Aminoglycosides towards the Eukaryotic and Prokaryotic Decoding A Sites.
Chembiochem, 8, 2007
1M5I
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Crystal Structure of the coiled coil region 129-250 of the tumor suppressor gene product APC
分子名称: APC protein
著者Tickenbrock, L, Cramer, J, Vetter, I.R, Mueller, O.
登録日2002-07-09
公開日2002-11-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The coiled coil region (amino acids 129-250) of the tumor suppressor protein adenomatous polyposis coli (APC). Its structure and its interaction with chromosome maintenance region 1 (Crm-1).
J.Biol.Chem., 277, 2002
5Y8T
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Crystal structure of Bacillus subtilis PadR in complex with p-coumaric acid
分子名称: 4'-HYDROXYCINNAMIC ACID, Transcriptional regulator
著者Park, S.C, Kwak, Y.M, Song, W.S, Hong, M, Yoon, S.I.
登録日2017-08-21
公開日2017-11-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of effector and operator recognition by the phenolic acid-responsive transcriptional regulator PadR.
Nucleic Acids Res., 45, 2017
5DD6
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Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
分子名称: ANTI-HIV ANTIBODY DH570.mut58 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570.mut58 FAB LIGHT CHAIN
著者Nicely, N.I, Pemble IV, C.W, Haynes, B.F.
登録日2015-08-24
公開日2016-05-11
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (1.699 Å)
主引用文献Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
Sci Transl Med, 8, 2016
1M7U
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Crystal structure of a novel DNA-binding domain from Ndt80, a transcriptional activator required for meiosis in yeast
分子名称: Ndt80 protein
著者Montano, S.P, Cote, M.L, Fingerman, I, Pierce, M, Vershon, A.K, Georgiadis, M.M.
登録日2002-07-22
公開日2002-11-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the DNA-binding domain from Ndt80, a transcriptional activator required for meiosis in yeast
Proc.Natl.Acad.Sci.USA, 99, 2002
1VDZ
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Crystal structure of A-type ATPase catalytic subunit A from Pyrococcus horikoshii OT3
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, A-type ATPase subunit A
著者Maegawa, Y, Morita, H, Yao, M, Watanabe, N, Tanaka, I.
登録日2004-03-26
公開日2005-06-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of A-type ATPase catalytic subunit A from Pyrococcus horikoshii OT3
To be Published
2OAJ
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Crystal structure of Sro7 from S. cerevisiae
分子名称: Protein SNI1, SODIUM ION, ZINC ION
著者Hattendorf, D.A, Weis, W.I.
登録日2006-12-15
公開日2007-04-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the yeast polarity protein Sro7 reveals a SNARE regulatory mechanism.
Nature, 446, 2007
1M5D
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X-RAY STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J-Y702F) IN COMPLEX WITH Br-HIBO AT 1.73 A RESOLUTION
分子名称: (S)-2-AMINO-3-(4-BROMO-3-HYDROXY-ISOXAZOL-5-YL)PROPIONIC ACID, Glutamate receptor 2, SULFATE ION
著者Hogner, A, Kastrup, J.S, Jin, R, Liljefors, T, Mayer, M.L, Egebjerg, J, Larsen, I.K, Gouaux, E.
登録日2002-07-09
公開日2002-09-18
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structural Basis for AMPA Receptor Activation and Ligand Selectivity: Crystal Structures of Five Agonist Complexes with the GluR2 Ligand-binding Core
J.Mol.Biol., 322, 2002
1VFF
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beta-glycosidase from Pyrococcus horikoshii
分子名称: beta-glucosidase
著者Akiba, T, Nishio, M, Matsui, I, Harata, K.
登録日2004-04-12
公開日2005-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献X-ray structure of a membrane-bound beta-glycosidase from the hyperthermophilic archaeon Pyrococcus horikoshii
Proteins, 57, 2004
6FJW
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Streptococcus thermophilus Cas6
分子名称: CALCIUM ION, Cas6 protein
著者Tamulaitiene, G, Mogila, I, Siksnys, V, Tamulaitis, G.
登録日2018-01-23
公開日2019-02-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Streptococcus thermophilus Cas6
To be published
5T80
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Crystal structure of 10E8 Fab in complex with the MPER epitope scaffold T117v2 and phosphatidic acid (06:0 PA)
分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 10E8 EPITOPE SCAFFOLD T117V2, Antibody 10E8 FAB HEAVY CHAIN, ...
著者Irimia, A, Wilson, I.A.
登録日2016-09-06
公開日2017-03-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.
PLoS Pathog., 13, 2017
2ZFA
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Structure of Lactate Oxidase at pH4.5 from AEROCOCCUS VIRIDANS
分子名称: 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, Lactate oxidase
著者Furuichi, M, Balasundaresan, D, Suzuki, N, Yoshida, Y, Minagawa, H, Kaneko, H, Waga, I, Kumar, P.K.R, Mizuno, H.
登録日2007-12-26
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献X-ray structures of Aerococcus viridans lactate oxidase and its complex with D-lactate at pH 4.5 show an alpha-hydroxyacid oxidation mechanism
J.Mol.Biol., 378, 2008
5DD5
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Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
分子名称: ANTI-HIV ANTIBODY DH570.9 FAB HEAVY CHAIN
著者Nicely, N.I, Pemble IV, C.W, Haynes, B.F.
登録日2015-08-24
公開日2016-05-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
Sci Transl Med, 8, 2016

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