2XH9
 
 | | Structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway | | 分子名称: | (2R,3Z,5R)-3-(2-HYDROXYETHYLIDENE)-7-OXO-4-OXA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, ORF12 | | 著者 | Iqbal, A, Valegard, K, Kershaw, N.J, Ivison, D, Genereux, C, Dubus, A, Andersson, I, Schofield, C.J. | | 登録日 | 2010-06-09 | | 公開日 | 2011-06-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural and mechanistic studies of the orf12 gene product from the clavulanic acid biosynthesis pathway.
Acta Crystallogr. D Biol. Crystallogr., 69, 2013
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4KWT
 | | Crystal structure of unliganded anabolic ornithine carbamoyltransferase from Vibrio vulnificus at 1.86 A resolution | | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Ornithine carbamoyltransferase | | 著者 | Shabalin, I.G, Bacal, P, Bajor, J, Winsor, J, Grimshaw, S, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2013-05-24 | | 公開日 | 2013-06-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Crystal structures and kinetic properties of anabolic ornithine carbamoyltransferase from human pathogens Vibrio vulnificus and Bacillus anthracis
To be Published
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2XEP
 | | Structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway | | 分子名称: | CHLORIDE ION, GLYCEROL, ORF12 | | 著者 | Iqbal, A, Valegard, K, Kershaw, N.J, Ivison, D, Genereux, C, Dubus, A, Andersson, I, Schofield, C.J. | | 登録日 | 2010-05-17 | | 公開日 | 2011-06-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural and mechanistic studies of the orf12 gene product from the clavulanic acid biosynthesis pathway.
Acta Crystallogr. D Biol. Crystallogr., 69, 2013
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4L1L
 | | Rat PKC C2 domain bound to CD | | 分子名称: | CADMIUM ION, Protein kinase C alpha type, SULFATE ION | | 著者 | Morales, K.M, Yang, Y, Long, Z, Li, P, Taylor, A.B, Hart, P.J, Igumenova, T.I. | | 登録日 | 2013-06-03 | | 公開日 | 2013-08-28 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Cd(2+) as a ca(2+) surrogate in protein-membrane interactions: isostructural but not isofunctional.
J.Am.Chem.Soc., 135, 2013
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2XGN
 | | Structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway | | 分子名称: | GLYCEROL, ORF12 | | 著者 | Iqbal, A, Valegard, K, Kershaw, N.J, Ivison, D, Genereux, C, Dubus, A, Andersson, I, Schofield, C.J. | | 登録日 | 2010-06-07 | | 公開日 | 2011-06-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and mechanistic studies of the orf12 gene product from the clavulanic acid biosynthesis pathway.
Acta Crystallogr. D Biol. Crystallogr., 69, 2013
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6I7U
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3QLP
 | | X-ray structure of the complex between human alpha thrombin and a modified thrombin binding aptamer (mTBA) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, POTASSIUM ION, ... | | 著者 | Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F. | | 登録日 | 2011-02-03 | | 公開日 | 2011-10-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Thrombin-aptamer recognition: a revealed ambiguity.
Nucleic Acids Res., 39, 2011
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5JUB
 | | Crystal structure of ComR from S.thermophilus in complex with DNA and its signalling peptide ComS. | | 分子名称: | ComS, Transcriptional regulator, pComX-for, ... | | 著者 | Talagas, A, Fontaine, L, Ledesma-Garcia, L, Li de la Sierra-Gallay, I, Hols, P, Nessler, S. | | 登録日 | 2016-05-10 | | 公開日 | 2016-10-26 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Structural Insights into Streptococcal Competence Regulation by the Cell-to-Cell Communication System ComRS.
PLoS Pathog., 12, 2016
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3H5B
 | | Crystal structure of wild type HIV-1 protease with novel P1'-ligand GRL-02031 | | 分子名称: | (3aS,5R,6aR)-hexahydro-2H-cyclopenta[b]furan-5-yl [(1S,2R)-1-benzyl-2-hydroxy-3-([(4-methoxyphenyl)sulfonyl]{[(2R)-5-oxopyrrolidin-2-yl]methyl}amino)propyl]carbamate, CHLORIDE ION, GLYCEROL, ... | | 著者 | Tie, Y, Wang, Y.F, Weber, I.T. | | 登録日 | 2009-04-21 | | 公開日 | 2009-06-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | | 主引用文献 | Design of HIV-1 protease inhibitors with pyrrolidinones and oxazolidinones as novel P1'-ligands to enhance backbone-binding interactions with protease: synthesis, biological evaluation, and protein-ligand X-ray studies.
J.Med.Chem., 52, 2009
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5JUF
 | | Crystal structure of the apo form of ComR from S. thermophilus. | | 分子名称: | SULFATE ION, Transcriptional regulator | | 著者 | Talagas, A, Fontaine, L, Ledesma, L, Li de la Sierra-Gallay, I, Hols, P, Nessler, S. | | 登録日 | 2016-05-10 | | 公開日 | 2016-10-26 | | 最終更新日 | 2016-12-14 | | 実験手法 | X-RAY DIFFRACTION (1.946 Å) | | 主引用文献 | Structural Insights into Streptococcal Competence Regulation by the Cell-to-Cell Communication System ComRS.
PLoS Pathog., 12, 2016
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4GY4
 | | Role of the biradical intermediate observed during the turnover of SLAC: A two-domain laccase from Streptomyces coelicolor | | 分子名称: | COPPER (II) ION, OXYGEN ATOM, Putative copper oxidase, ... | | 著者 | Nederlof, I, Gupta, A, Canters, G.W. | | 登録日 | 2012-09-05 | | 公開日 | 2012-09-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | Involvement of Tyr108 in the enzyme mechanism of the small laccase from Streptomyces coelicolor
J.Am.Chem.Soc., 134, 2012
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4GSJ
 | | Crystal structure of Atg7 NTD K14A F16A D18A mutant | | 分子名称: | CITRIC ACID, ISOPROPYL ALCOHOL, Ubiquitin-like modifier-activating enzyme ATG7 | | 著者 | Kaiser, S.E, Mao, K, Taherbhoy, A.M, Yu, S, Olszewski, J.L, Duda, D.M, Kurinov, I, Deng, A, Fenn, T.D, Klionsky, D.J, Schulman, B.A. | | 登録日 | 2012-08-27 | | 公開日 | 2012-11-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.695 Å) | | 主引用文献 | Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7-Atg3 and Atg7-Atg10 structures.
Nat.Struct.Mol.Biol., 19, 2012
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3GJQ
 | | Caspase-3 Binds Diverse P4 Residues in Peptides | | 分子名称: | Caspase-3 subunit p12, Caspase-3 subunit p17, peptide inhibitor | | 著者 | Fang, B, Fu, G, Agniswamy, J, Harrison, R.W, Weber, I.T. | | 登録日 | 2009-03-09 | | 公開日 | 2009-03-24 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Caspase-3 binds diverse P4 residues in peptides as revealed by crystallography and structural modeling.
Apoptosis, 14, 2009
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3QKL
 | | Spirochromane Akt Inhibitors | | 分子名称: | GSK-3 beta peptide, N-{(2S)-3-[(3S)-8',9'-dihydro-1H,3'H-spiro[piperidine-3,7'-pyrano[3,2-e]indazol]-1-yl]-2-hydroxypropyl}-N-(2-ethoxyethyl)-2,6-dimethylbenzenesulfonamide, RAC-alpha serine/threonine-protein kinase | | 著者 | Kallan, N.C, Spencer, K.L, Blake, J.F, Xu, R, Heizer, J, Bencsik, J.R, Mitchell, I.S, Gloor, S.L, Martinson, M, Risom, T, Gross, S.D, Morales, T, Vigers, G.P.A, Brandhuber, B.J, Skelton, N.J. | | 登録日 | 2011-02-01 | | 公開日 | 2011-03-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Discovery and SAR of spirochromane Akt inhibitors.
Bioorg.Med.Chem.Lett., 21, 2011
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3GYY
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5JZA
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5JZU
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6ILB
 | | Native crystal structure of fructuronate-tagaturonate epimerase UxaE from Cohnella laeviribosi | | 分子名称: | 1,2-ETHANEDIOL, Fructuronate-tagaturonate epimerase UxaE, MANGANESE (II) ION | | 著者 | Choi, M.Y, Kang, L.W, Ho, T.H, Nguyen, D.Q, Lee, I.H, Lee, J.H, Park, Y.S, Park, H.J. | | 登録日 | 2018-10-17 | | 公開日 | 2019-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Crystal structure of fructuronate-tagaturonate epimerase UxaE from Cohnella laeviribosi
To be published
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1YLR
 | | The structure of E.coli nitroreductase with bound acetate, crystal form 1 | | 分子名称: | ACETATE ION, FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase | | 著者 | Race, P.R, Lovering, A.L, Green, R.M, Ossor, A, White, S.A, Searle, P.F, Wrighton, C.J, Hyde, E.I. | | 登録日 | 2005-01-19 | | 公開日 | 2005-02-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme.
J.Biol.Chem., 280, 2005
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5JS2
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1QKJ
 | | T4 Phage B-Glucosyltransferase, Substrate Binding and Proposed Catalytic Mechanism | | 分子名称: | BETA-GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE | | 著者 | Morera, S, Imberty, I, Aschke-Sonnenborn, U, Ruger, W, Freemont, P.S. | | 登録日 | 1999-07-22 | | 公開日 | 1999-07-28 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | T4 Phage Beta-Glucosyltransferase: Substrate Binding and Proposed Catalytic Mechanism
J.Mol.Biol., 292, 1999
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3H64
 | | Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c) with two Mn2+ atoms complexed with endothall | | 分子名称: | (1R,2S,3R,4S)-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid, MANGANESE (II) ION, Serine/threonine-protein phosphatase 5 | | 著者 | Bertini, I, Calderone, V, Fragai, M, Luchinat, C, Talluri, E. | | 登録日 | 2009-04-23 | | 公開日 | 2009-09-29 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis of serine/threonine phosphatase inhibition by the archetypal small molecules cantharidin and norcantharidin
J.Med.Chem., 52, 2009
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4H9M
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3H9B
 | | Structure of a mutant methionyl-tRNA synthetase with modified specificity complexed with azidonorleucine | | 分子名称: | 6-azido-L-norleucine, CITRIC ACID, Methionyl-tRNA synthetase, ... | | 著者 | Schmitt, E, Tanrikulu, I.C, Yoo, T.H, Panvert, M, Tirrell, D.A, Mechulam, Y. | | 登録日 | 2009-04-30 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Switching from an induced-fit to a lock-and-key mechanism in an aminoacyl-tRNA synthetase with modified specificity.
J.Mol.Biol., 394, 2009
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6HNM
 | | Crystal structure of IdmH 96-104 loop truncation variant | | 分子名称: | putative polyketide cyclase IdmH | | 著者 | Drulyte, I, Obajdin, J, Trinh, C, Hemsworth, G.R, Berry, A. | | 登録日 | 2018-09-16 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the putative cyclase IdmH from the indanomycin nonribosomal peptide synthase/polyketide synthase.
Iucrj, 6, 2019
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