8D9U
| AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes, centered on beta-Arf1 | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | Authors: | Hooy, R.M, Hurley, J.H. | Deposit date: | 2022-06-11 | Release date: | 2022-11-09 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (20 Å) | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat. Sci Adv, 8, 2022
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6CM9
| Structure of the cargo bound AP-1:Arf1:tetherin-Nef closed trimer monomeric subunit | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | Authors: | Morris, K.L, Buffalo, C.Z, Ren, X, Hurley, J.H. | Deposit date: | 2018-03-03 | Release date: | 2018-08-08 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.73 Å) | Cite: | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
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6DFF
| Structure of the cargo bound AP-1:Arf1:tetherin-Nef monomer | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | Authors: | Morris, K.L, Buffalo, C.Z, Ren, X, Hurley, J.H. | Deposit date: | 2018-05-14 | Release date: | 2018-08-08 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
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6D84
| Structure of the cargo bound AP-1:Arf1:tetherin-Nef (L164A, L165A) dileucine mutant dimer | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | Authors: | Buffalo, C.Z, Morris, K.L, Hurley, J.H. | Deposit date: | 2018-04-25 | Release date: | 2018-08-08 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (6.72 Å) | Cite: | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
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1GRP
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5JW9
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1GRO
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8D4F
| beta-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated wide(r) membrane tubes | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | Authors: | Hooy, R.M, Hurley, J.H. | Deposit date: | 2022-06-01 | Release date: | 2023-06-14 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (9.8 Å) | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat. Sci Adv, 8, 2022
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8D4G
| gamma-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated wide(r) membrane tubes | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | Authors: | Hooy, R.M, Hurley, J.H. | Deposit date: | 2022-06-01 | Release date: | 2023-06-14 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (11.6 Å) | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat. Sci Adv, 8, 2022
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8D4D
| gamma-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated narrow membrane tubes | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | Authors: | Hooy, R.M, Hurley, J.H. | Deposit date: | 2022-06-01 | Release date: | 2023-06-14 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (9.6 Å) | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat. Sci Adv, 8, 2022
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8D9W
| beta-Arf1 homodimeric interface within AP-1, Arf1, Nef, MHC-I lattice on narrow tubes | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | Authors: | Hooy, R.H, Hurley, J.H. | Deposit date: | 2022-06-11 | Release date: | 2023-07-05 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (9.3 Å) | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat. Sci Adv, 8, 2022
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8D4C
| beta-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated narrow membrane tubes | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | Authors: | Hooy, R.M, Hurley, J.H. | Deposit date: | 2022-06-01 | Release date: | 2023-06-14 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (9.3 Å) | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat. Sci Adv, 8, 2022
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8DHB
| Active FLCN GAP complex | Descriptor: | BERYLLIUM TRIFLUORIDE ION, Folliculin, Folliculin-interacting protein 2, ... | Authors: | Jansen, R.M, Hurley, J.H. | Deposit date: | 2022-06-25 | Release date: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.53 Å) | Cite: | Structural basis for FLCN RagC GAP activation in MiT-TFE substrate-selective mTORC1 regulation. Sci Adv, 8, 2022
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8D4E
| Asymmetric unit of AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide(r) membrane tubes | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | Authors: | Hooy, R.M, Hurley, J.H. | Deposit date: | 2022-06-01 | Release date: | 2023-06-14 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (9.2 Å) | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat. Sci Adv, 8, 2022
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8DO8
| Crystal structure ATG9 HDIR in complex with the ATG13:ATG101 HORMA dimer | Descriptor: | Autophagy-related protein 101, Autophagy-related protein 13, GLYCEROL | Authors: | Buffalo, C.Z, Ren, X, Yokom, A.L, Hurley, J.H. | Deposit date: | 2022-07-12 | Release date: | 2022-11-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation. Sci Adv, 9, 2023
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3F1I
| Human ESCRT-0 Core Complex | Descriptor: | Hepatocyte growth factor-regulated tyrosine kinase substrate, Signal transducing adapter molecule 1 | Authors: | Ren, X, Kloer, D.P, Kim, Y, Ghirlando, R, Saidi, L, Hummer, G, Hurley, J.H. | Deposit date: | 2008-10-28 | Release date: | 2009-03-24 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Hybrid Structural Model of the Complete Human ESCRT-0 Complex. Structure, 17, 2009
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1ZB1
| Structure basis for endosomal targeting by the Bro1 domain | Descriptor: | BRO1 protein | Authors: | Kim, J, Sitaraman, S, Hierro, A, Beach, B.M, Odorizzi, G, Hurley, J.H. | Deposit date: | 2005-04-07 | Release date: | 2005-06-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis for endosomal targeting by the Bro1 domain. Dev.Cell, 8, 2005
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1ZHT
| Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol | Descriptor: | 7-HYDROXYCHOLESTEROL, KES1 protein | Authors: | Im, Y.J, Raychaudhuri, S, Prinz, W.A, Hurley, J.H. | Deposit date: | 2005-04-26 | Release date: | 2005-09-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural mechanism for sterol sensing and transport by OSBP-related proteins Nature, 437, 2005
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1Z2O
| Inositol 1,3,4-trisphosphate 5/6-Kinase in complex with mg2+/ADP/Ins(1,3,4,6)P4 | Descriptor: | (1S,3R,4R,6S)-1,3,4,6-TETRAPKISPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Miller, G.J, Wilson, M.P, Majerus, P.W, Hurley, J.H. | Deposit date: | 2005-03-08 | Release date: | 2005-04-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.24 Å) | Cite: | Specificity determinants in inositol polyphosphate synthesis: crystal structure of inositol 1,3,4-trisphosphate 5/6-kinase. Mol.Cell, 18, 2005
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1ZHZ
| Structure of yeast oxysterol binding protein Osh4 in complex with ergosterol | Descriptor: | ERGOSTEROL, KES1 protein, LEAD (II) ION | Authors: | Im, Y.J, Raychaudhuri, S, Prinz, W.A, Hurley, J.H. | Deposit date: | 2005-04-26 | Release date: | 2005-09-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural mechanism for sterol sensing and transport by OSBP-related proteins Nature, 437, 2005
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1ZHY
| Structure of yeast oxysterol binding protein Osh4 in complex with cholesterol | Descriptor: | CHOLESTEROL, KES1 protein, LEAD (II) ION | Authors: | Im, Y.J, Raychaudhuri, S, Prinz, W.A, Hurley, J.H. | Deposit date: | 2005-04-26 | Release date: | 2005-09-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural mechanism for sterol sensing and transport by OSBP-related proteins Nature, 437, 2005
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4N7H
| Crystal Structure of the Complex of 3rd WW domain of Human Nedd4 and 1st PPXY Motif of ARRDC3 | Descriptor: | Arrestin domain-containing protein 3, E3 ubiquitin-protein ligase NEDD4, GUANIDINE | Authors: | Qi, S, O'Hayre, M, Gutkind, J.S, Hurley, J. | Deposit date: | 2013-10-15 | Release date: | 2014-01-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.698 Å) | Cite: | Structural and biochemical basis for ubiquitin ligase recruitment by arrestin-related domain-containing protein-3 (ARRDC3). J.Biol.Chem., 289, 2014
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2F66
| Structure of the ESCRT-I endosomal trafficking complex | Descriptor: | Protein SRN2, SULFATE ION, Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease, ... | Authors: | Kostelansky, M.S, Lee, S, Kim, J, Hurley, J.H. | Deposit date: | 2005-11-28 | Release date: | 2006-04-18 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and functional organization of the ESCRT-I trafficking complex. Cell(Cambridge,Mass.), 125, 2006
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3R3Q
| Crystal structure of the yeast Vps23 UEV domain | Descriptor: | ACETATE ION, CHLORIDE ION, IMIDAZOLE, ... | Authors: | Ren, X, Hurley, J.H. | Deposit date: | 2011-03-16 | Release date: | 2011-05-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural basis for endosomal recruitment of ESCRT-I by ESCRT-0 in yeast. Embo J., 30, 2011
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2F6M
| Structure of a Vps23-C:Vps28-N subcomplex | Descriptor: | DECYLAMINE-N,N-DIMETHYL-N-OXIDE, MAGNESIUM ION, Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease, ... | Authors: | Kostelansky, M.S, Lee, S, Kim, J, Hurley, J.H. | Deposit date: | 2005-11-29 | Release date: | 2006-04-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and functional organization of the ESCRT-I trafficking complex. Cell(Cambridge,Mass.), 125, 2006
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