1GRP
 
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6DFF
 | | Structure of the cargo bound AP-1:Arf1:tetherin-Nef monomer | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Morris, K.L, Buffalo, C.Z, Ren, X, Hurley, J.H. | | Deposit date: | 2018-05-14 | | Release date: | 2018-08-08 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
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6D84
 | | Structure of the cargo bound AP-1:Arf1:tetherin-Nef (L164A, L165A) dileucine mutant dimer | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Buffalo, C.Z, Morris, K.L, Hurley, J.H. | | Deposit date: | 2018-04-25 | | Release date: | 2018-08-08 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (6.72 Å) | | Cite: | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
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2ICP
 | | Crystal structure of the bacterial antitoxin HigA from Escherichia coli at pH 4.0. Northeast Structural Genomics Consortium TARGET ER390. | | Descriptor: | MAGNESIUM ION, antitoxin higa | | Authors: | Arbing, M.A, Abashidze, M, Hurley, J.M, Zhao, L, Janjua, H, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Inouye, M, Woychik, N.A, Montelione, G.T, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2006-09-13 | | Release date: | 2006-09-26 | | Last modified: | 2019-07-24 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Crystal structure of the bacterial antitoxin HigA from Escherichia coli.
To be Published
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2ICT
 | | Crystal structure of the bacterial antitoxin HigA from Escherichia coli at pH 8.5. Northeast Structural Genomics TARGET ER390. | | Descriptor: | antitoxin higa | | Authors: | Arbing, M.A, Abashidze, M, Hurley, J.M, Zhao, L, Janjua, H, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Inouye, M, Woychik, N.A, Montelione, G.T, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2006-09-13 | | Release date: | 2006-09-26 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Crystal Structures of Phd-Doc, HigA, and YeeU Establish Multiple Evolutionary Links between Microbial Growth-Regulating Toxin-Antitoxin Systems.
Structure, 18, 2010
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3E1R
 | | Midbody targeting of the ESCRT machinery by a non-canonical coiled-coil in CEP55 | | Descriptor: | Centrosomal protein of 55 kDa, Programmed cell death 6-interacting protein | | Authors: | Lee, H.H, Elia, N, Ghirlando, R, Lippincott-Schwartz, J, Hurley, J.H. | | Deposit date: | 2008-08-04 | | Release date: | 2008-11-04 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Midbody targeting of the ESCRT machinery by a noncanonical coiled coil in CEP55.
Science, 322, 2008
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7MU2
 | | Crystal Structure of WIPI2 in complex with W2IR of ATG16L1 | | Descriptor: | Autophagy-related protein 16-1, WD repeat domain phosphoinositide-interacting protein 2 | | Authors: | Strong, L.M, Flower, T.G, Buffalo, C.Z, Hurley, J.H. | | Deposit date: | 2021-05-14 | | Release date: | 2021-05-26 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy.
Elife, 10, 2021
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7MGE
 | | Structure of C9orf72:SMCR8:WDR41 in complex with ARF1 | | Descriptor: | ADP-ribosylation factor 1, BERYLLIUM TRIFLUORIDE ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Su, M.-Y, Hurley, J.H. | | Deposit date: | 2021-04-12 | | Release date: | 2021-06-23 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.94 Å) | | Cite: | Structural basis for the ARF GAP activity and specificity of the C9orf72 complex.
Nat Commun, 12, 2021
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8D9V
 | | gamma-Arf1 homodimeric interface within AP-1, Arf1, Nef lattice on narrow membrane tubes | | Descriptor: | ADP ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-11 | | Release date: | 2022-11-09 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (9.4 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8D9S
 | | AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide membrane tubes, centered on beta-Arf1 | | Descriptor: | ADP ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-11 | | Release date: | 2022-11-09 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (20 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8D9T
 | | AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes, centered on gamma-Arf1 | | Descriptor: | ADP ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-11 | | Release date: | 2022-11-09 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (20 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8D9U
 | | AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes, centered on beta-Arf1 | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-11 | | Release date: | 2022-11-09 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (20 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8D9R
 | | AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide membrane tubes, centered on gamma-Arf1 | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-11 | | Release date: | 2022-11-09 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (20 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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3HTU
 | | Crystal structure of the human VPS25-VPS20 subcomplex | | Descriptor: | Vacuolar protein-sorting-associated protein 20, Vacuolar protein-sorting-associated protein 25 | | Authors: | Im, Y.J, Hurley, J.H. | | Deposit date: | 2009-06-12 | | Release date: | 2009-08-25 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure and function of the ESCRT-II-III interface in multivesicular body biogenesis.
Dev.Cell, 17, 2009
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8D4F
 | | beta-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated wide(r) membrane tubes | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-01 | | Release date: | 2023-06-14 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (9.8 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8D4G
 | | gamma-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated wide(r) membrane tubes | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-01 | | Release date: | 2023-06-14 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (11.6 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8D4D
 | | gamma-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated narrow membrane tubes | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-01 | | Release date: | 2023-06-14 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (9.6 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8D4C
 | | beta-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated narrow membrane tubes | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-01 | | Release date: | 2023-06-14 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (9.3 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8D9W
 | | beta-Arf1 homodimeric interface within AP-1, Arf1, Nef, MHC-I lattice on narrow tubes | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.H, Hurley, J.H. | | Deposit date: | 2022-06-11 | | Release date: | 2023-07-05 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (9.3 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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4EXV
 | | Structure of Kluyveromyces lactis Hsv2p | | Descriptor: | SULFATE ION, SVP1-like protein 2 | | Authors: | Baskaran, S, Hurley, J.H. | | Deposit date: | 2012-05-01 | | Release date: | 2012-07-04 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Two-Site Recognition of Phosphatidylinositol 3-Phosphate by PROPPINs in Autophagy.
Mol.Cell, 47, 2012
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3F1I
 | | Human ESCRT-0 Core Complex | | Descriptor: | Hepatocyte growth factor-regulated tyrosine kinase substrate, Signal transducing adapter molecule 1 | | Authors: | Ren, X, Kloer, D.P, Kim, Y, Ghirlando, R, Saidi, L, Hummer, G, Hurley, J.H. | | Deposit date: | 2008-10-28 | | Release date: | 2009-03-24 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Hybrid Structural Model of the Complete Human ESCRT-0 Complex.
Structure, 17, 2009
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3R3Q
 | | Crystal structure of the yeast Vps23 UEV domain | | Descriptor: | ACETATE ION, CHLORIDE ION, IMIDAZOLE, ... | | Authors: | Ren, X, Hurley, J.H. | | Deposit date: | 2011-03-16 | | Release date: | 2011-05-04 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structural basis for endosomal recruitment of ESCRT-I by ESCRT-0 in yeast.
Embo J., 30, 2011
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4N7H
 | | Crystal Structure of the Complex of 3rd WW domain of Human Nedd4 and 1st PPXY Motif of ARRDC3 | | Descriptor: | Arrestin domain-containing protein 3, E3 ubiquitin-protein ligase NEDD4, GUANIDINE | | Authors: | Qi, S, O'Hayre, M, Gutkind, J.S, Hurley, J. | | Deposit date: | 2013-10-15 | | Release date: | 2014-01-08 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.698 Å) | | Cite: | Structural and biochemical basis for ubiquitin ligase recruitment by arrestin-related domain-containing protein-3 (ARRDC3).
J.Biol.Chem., 289, 2014
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4N7F
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8DHB
 | | Active FLCN GAP complex | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, Folliculin, Folliculin-interacting protein 2, ... | | Authors: | Jansen, R.M, Hurley, J.H. | | Deposit date: | 2022-06-25 | | Release date: | 2022-09-28 | | Method: | ELECTRON MICROSCOPY (3.53 Å) | | Cite: | Structural basis for FLCN RagC GAP activation in MiT-TFE substrate-selective mTORC1 regulation.
Sci Adv, 8, 2022
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