8C1V
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![BU of 8c1v by Molmil](/molmil-images/mine/8c1v) | SARS-CoV-2 S-trimer (3 RBDs up) bound to TriSb92, fitted into cryo-EM map | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Sb92, ... | Authors: | Huiskonen, J.T, Rissanen, I, Hannula, L. | Deposit date: | 2022-12-21 | Release date: | 2023-04-19 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Intranasal trimeric sherpabody inhibits SARS-CoV-2 including recent immunoevasive Omicron subvariants. Nat Commun, 14, 2023
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5OXE
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![BU of 5oxe by Molmil](/molmil-images/mine/5oxe) | |
5K47
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![BU of 5k47 by Molmil](/molmil-images/mine/5k47) | CryoEM structure of the human Polycystin-2/PKD2 TRP channel | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Polycystin-2 | Authors: | Pike, A.C.W, Grieben, M, Shintre, C.A, Tessitore, A, Shrestha, L, Mukhopadhyay, S, Mahajan, P, Chalk, R, Burgess-Brown, N.A, Huiskonen, J.T, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | Deposit date: | 2016-05-20 | Release date: | 2016-08-24 | Last modified: | 2020-10-21 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2). Nat. Struct. Mol. Biol., 24, 2017
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5D8A
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![BU of 5d8a by Molmil](/molmil-images/mine/5d8a) | Crystal structure of recombinant foot-and-mouth-disease virus A22-H2093F empty capsid | Descriptor: | VP1, VP2, VP3, ... | Authors: | Kotecha, A, Seago, J, Scott, K, Burman, A, Loureiro, S, Ren, J, Porta, C, Ginn, H.M, Jackson, T, Perez-Martin, E, Siebert, C.A, Paul, G, Huiskonen, J.T, Jones, I.M, Esnouf, R.M, Fry, E.E, Maree, F.F, Charleston, B, Stuart, D.I. | Deposit date: | 2015-08-16 | Release date: | 2015-09-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design. Nat.Struct.Mol.Biol., 22, 2015
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5DDJ
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![BU of 5ddj by Molmil](/molmil-images/mine/5ddj) | Crystal structure of recombinant foot-and-mouth-disease virus O1M-S2093Y empty capsid | Descriptor: | Foot and mouth disease virus, VP1, VP2, ... | Authors: | Kotecha, A, Seago, J, Scott, K, Burman, A, Loureiro, S, Ren, J, Porta, C, Ginn, H.M, Jackson, T, Perez-Martin, E, Siebert, C.A, Paul, G, Huiskonen, J.T, Jones, I.M, Esnouf, R.M, Fry, E.E, Maree, F.F, Charleston, B, Stuart, D.I. | Deposit date: | 2015-08-25 | Release date: | 2015-09-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design. Nat.Struct.Mol.Biol., 22, 2015
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8A06
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![BU of 8a06 by Molmil](/molmil-images/mine/8a06) | |
7ZZZ
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![BU of 7zzz by Molmil](/molmil-images/mine/7zzz) | Bacteriophage phiCjT23 capsid | Descriptor: | Major capsid protein P5, Spike protein P13 N-terminal, capsid internal domain, ... | Authors: | Rissanen, I, Kejzar, N, Huiskonen, J.T. | Deposit date: | 2022-05-26 | Release date: | 2022-12-14 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Cryo-EM structure of ssDNA bacteriophage Phi CjT23 provides insight into early virus evolution. Nat Commun, 13, 2022
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8A03
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![BU of 8a03 by Molmil](/molmil-images/mine/8a03) | |
8BI4
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![BU of 8bi4 by Molmil](/molmil-images/mine/8bi4) | |
6J7V
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![BU of 6j7v by Molmil](/molmil-images/mine/6j7v) | |
8A05
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![BU of 8a05 by Molmil](/molmil-images/mine/8a05) | Bacteriophage phiCjT23 spike protein penton domain | Descriptor: | Spike protein P13 N-terminal, capsid internal domain, Unknown vertex protein | Authors: | Rissanen, I, Huiskonen, J.T. | Deposit date: | 2022-05-26 | Release date: | 2022-12-14 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structure of ssDNA bacteriophage Phi CjT23 provides insight into early virus evolution. Nat Commun, 13, 2022
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8A02
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![BU of 8a02 by Molmil](/molmil-images/mine/8a02) | |
8A01
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![BU of 8a01 by Molmil](/molmil-images/mine/8a01) | |
8A04
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![BU of 8a04 by Molmil](/molmil-images/mine/8a04) | |
7ZTC
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![BU of 7ztc by Molmil](/molmil-images/mine/7ztc) | Non-muscle F-actin decorated with non-muscle tropomyosin 1.6 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Non-muscle tropomyosin 1.6, actin, ... | Authors: | Selvaraj, M, Kokate, S, Kogan, K, Kotila, T, Kremneva, E, Lappalainen, P, Huiskonen, J.T. | Deposit date: | 2022-05-09 | Release date: | 2023-01-11 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis underlying specific biochemical activities of non-muscle tropomyosin isoforms. Cell Rep, 42, 2023
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7ZTD
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![BU of 7ztd by Molmil](/molmil-images/mine/7ztd) | Non-muscle F-actin decorated with non-muscle tropomyosin 3.2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Non-muscle tropomyosin 3.2, actin, ... | Authors: | Selvaraj, M, Kokate, S, Kogan, K, Kotila, T, Kremneva, E, Lappalainen, P, Huiskonen, J.T. | Deposit date: | 2022-05-09 | Release date: | 2023-01-11 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural basis underlying specific biochemical activities of non-muscle tropomyosin isoforms. Cell Rep, 42, 2023
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8P0V
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![BU of 8p0v by Molmil](/molmil-images/mine/8p0v) | Structure of the human Commander complex coiled coils, DENND10 and partial Retriever subcomplex | Descriptor: | Coiled-coil domain-containing protein 22, Coiled-coil domain-containing protein 93, DENN domain-containing protein 10, ... | Authors: | Kumpula, E.P, Laulumaa, S, Huiskonen, J.T. | Deposit date: | 2023-05-10 | Release date: | 2024-03-20 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | Structure and interactions of the endogenous human Commander complex. Nat.Struct.Mol.Biol., 31, 2024
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8BF9
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![BU of 8bf9 by Molmil](/molmil-images/mine/8bf9) | Molecular view of ER membrane remodeling by the Sec61/TRAP translocon. | Descriptor: | 60S ribosomal protein L39, Large ribosomal subunit protein eL31, Large ribosomal subunit protein eL38, ... | Authors: | Karki, S, Javanainen, M, Tranter, D, Rehan, S, Huiskonen, J, Happonen, L, Paavilainen, V. | Deposit date: | 2022-10-24 | Release date: | 2023-11-01 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (2.69 Å) | Cite: | Molecular view of ER membrane remodeling by the Sec61/TRAP translocon. Embo Rep., 24, 2023
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1GW8
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![BU of 1gw8 by Molmil](/molmil-images/mine/1gw8) | quasi-atomic resolution model of bacteriophage PRD1 sus607 mutant, obtained by combined cryo-EM and X-ray crystallography. | Descriptor: | MAJOR CAPSID PROTEIN | Authors: | San Martin, C, Huiskonen, J, Bamford, J.K.H, Butcher, S.J, Fuller, S.D, Bamford, D.H, Burnett, R.M. | Deposit date: | 2002-03-08 | Release date: | 2002-03-15 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (13.3 Å) | Cite: | Minor Proteins, Mobile Arms and Membrane-Capsid Interactions in the Bacteriophage Prd1 Capsid. Nat.Struct.Biol., 9, 2002
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8P0W
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![BU of 8p0w by Molmil](/molmil-images/mine/8p0w) | Structure of the human Commander complex COMMD ring | Descriptor: | COMM domain-containing protein 1, COMM domain-containing protein 10, COMM domain-containing protein 2, ... | Authors: | Kumpula, E.P, Laulumaa, S, Huiskonen, J.T. | Deposit date: | 2023-05-11 | Release date: | 2024-03-20 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure and interactions of the endogenous human Commander complex. Nat.Struct.Mol.Biol., 31, 2024
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7NVL
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![BU of 7nvl by Molmil](/molmil-images/mine/7nvl) | Human TRiC complex in closed state with nanobody bound (Consensus Map) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | Authors: | Kelly, J.J, Chi, G, Bulawa, C, Paavilainen, V.O, Bountra, C, Huiskonen, J.T, Yue, W, Structural Genomics Consortium (SGC) | Deposit date: | 2021-03-15 | Release date: | 2022-03-02 | Last modified: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Snapshots of actin and tubulin folding inside the TRiC chaperonin. Nat.Struct.Mol.Biol., 29, 2022
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7NVO
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![BU of 7nvo by Molmil](/molmil-images/mine/7nvo) | Human TRiC complex in open state with nanobody bound | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | Authors: | Kelly, J.J, Chi, G, Bulawa, C, Paavilainen, V.O, Bountra, C, Huiskonen, J.T, Yue, W. | Deposit date: | 2021-03-15 | Release date: | 2022-03-02 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Snapshots of actin and tubulin folding inside the TRiC chaperonin. Nat.Struct.Mol.Biol., 29, 2022
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7NVN
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![BU of 7nvn by Molmil](/molmil-images/mine/7nvn) | Human TRiC complex in closed state with nanobody and tubulin bound | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | Authors: | Kelly, J.J, Chi, G, Bulawa, C, Paavilainen, V.O, Bountra, C, Huiskonen, J.T, Yue, W. | Deposit date: | 2021-03-15 | Release date: | 2022-03-02 | Last modified: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Snapshots of actin and tubulin folding inside the TRiC chaperonin. Nat.Struct.Mol.Biol., 29, 2022
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7NVM
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![BU of 7nvm by Molmil](/molmil-images/mine/7nvm) | Human TRiC complex in closed state with nanobody Nb18, actin and PhLP2A bound | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Actin, ... | Authors: | Kelly, J.J, Chi, G, Bulawa, C, Paavilainen, V.O, Bountra, C, Huiskonen, J.T, Yue, W, Structural Genomics Consortium (SGC) | Deposit date: | 2021-03-15 | Release date: | 2022-03-02 | Last modified: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Snapshots of actin and tubulin folding inside the TRiC chaperonin. Nat.Struct.Mol.Biol., 29, 2022
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7Q8S
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![BU of 7q8s by Molmil](/molmil-images/mine/7q8s) | Leishmania major ADP-actin filament decorated with Leishmania major cofilin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADF/Cofilin, Actin, ... | Authors: | Kotila, T, Muniyandi, S, Lappalainen, P, Huiskonen, J.T. | Deposit date: | 2021-11-11 | Release date: | 2022-05-18 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite. Nat Commun, 13, 2022
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