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PDB: 67 件

2H9N
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BU of 2h9n by Molmil
WDR5 in complex with monomethylated H3K4 peptide
分子名称: H3 histone, WD-repeat protein 5
著者Min, J.R, Schuetz, A, Allali-Hassani, A, Martin, F, Loppnau, P, Vedadi, M, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2006-06-10
公開日2006-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for molecular recognition and presentation of histone H3 By WDR5.
Embo J., 25, 2006
2H9P
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BU of 2h9p by Molmil
WDR5 in complex with trimethylated H3K4 peptide
分子名称: H3 histone, WD-repeat protein 5
著者Min, J.R, Schuetz, A, Allali-Hassani, A, Martin, F, Loppnau, P, Vedadi, M, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2006-06-10
公開日2006-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Structural basis for molecular recognition and presentation of histone H3 By WDR5.
Embo J., 25, 2006
2B4Y
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BU of 2b4y by Molmil
Crystal Structure of Human Sirtuin homolog 5
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5-DIPHOSPHORIBOSE, NAD-dependent deacetylase sirtuin-5, ...
著者Min, J.R, Antoshenko, T, Dong, A, Schuetz, A, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2005-09-27
公開日2006-02-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of Human Sirtuin homolog 5 in complex with NAD
To be Published
3PHD
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BU of 3phd by Molmil
Crystal structure of human HDAC6 in complex with ubiquitin
分子名称: Histone deacetylase 6, Polyubiquitin, ZINC ION
著者Dong, A, Qui, W, Ravichandran, M, Schuetz, A, Loppnau, P, Li, F, Mackenzie, F, Kozieradzki, I, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2010-11-03
公開日2011-02-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Protein Aggregates Are Recruited to Aggresome by Histone Deacetylase 6 via Unanchored Ubiquitin C Termini.
J.Biol.Chem., 287, 2012
2GL8
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BU of 2gl8 by Molmil
Human Retinoic acid receptor RXR-gamma ligand-binding domain
分子名称: Retinoic acid receptor RXR-gamma
著者Min, J.R, Schuetz, A, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2006-04-04
公開日2006-04-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Crystal Structure of Human Retinoic acid receptor RXR-gamma ligand-binding domain.
To be Published
3ULJ
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BU of 3ulj by Molmil
Crystal structure of apo Lin28B cold shock domain
分子名称: ACETATE ION, GLYCEROL, Lin28b, ...
著者Mayr, F, Schuetz, A, Doege, N, Heinemann, U.
登録日2011-11-10
公開日2012-08-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.06 Å)
主引用文献The Lin28 cold-shock domain remodels pre-let-7 microRNA.
Nucleic Acids Res., 40, 2012
2YMA
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BU of 2yma by Molmil
X-ray structure of the Yos9 dimerization domain
分子名称: PROTEIN OS-9 HOMOLOG
著者Hanna, J, Schuetz, A, Zimmermann, F, Behlke, J, Sommer, T, Heinemann, U.
登録日2011-06-07
公開日2012-01-25
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.545 Å)
主引用文献Structural and Biochemical Basis of Yos9 Protein Dimerization and Possible Contribution to Self-Association of 3-Hydroxy-3-Methylglutaryl-Coenzyme a Reductase Degradation Ubiquitin-Ligase Complex.
J.Biol.Chem., 287, 2012
5MPH
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BU of 5mph by Molmil
Structural Basis of Gene Regulation by the Grainyhead Transcription Factor Superfamily
分子名称: Grainyhead-like protein 1 homolog, IODIDE ION
著者Ming, Q, Roske, Y, Schuetz, A, Walentin, K, Ibraimi, I, Schmidt-Ott, K.M, Heinemann, U.
登録日2016-12-16
公開日2018-01-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.337 Å)
主引用文献Structural basis of gene regulation by the Grainyhead/CP2 transcription factor family.
Nucleic Acids Res., 46, 2018
5MPF
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Structural Basis of Gene Regulation by the Grainyhead Transcription Factor Superfamily
分子名称: DNA (5'-D(*AP*AP*AP*AP*CP*CP*GP*GP*TP*TP*TP*T)-3'), Grainyhead-like protein 1 homolog
著者Ming, Q, Roske, Y, Schuetz, A, Walentin, K, Ibraimi, I, Schmidt-Ott, K.M, Heinemann, U.
登録日2016-12-16
公開日2018-01-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.918 Å)
主引用文献Structural basis of gene regulation by the Grainyhead/CP2 transcription factor family.
Nucleic Acids Res., 46, 2018
5MPI
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BU of 5mpi by Molmil
Structural Basis of Gene Regulation by the Grainyhead Transcription Factor Superfamily
分子名称: Grainyhead-like protein 1 homolog
著者Ming, Q, Roske, Y, Schuetz, A, Walentin, K, Ibraimi, I, Schmidt-Ott, K.M, Heinemann, U.
登録日2016-12-16
公開日2018-01-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.345 Å)
主引用文献Structural basis of gene regulation by the Grainyhead/CP2 transcription factor family.
Nucleic Acids Res., 46, 2018
4ALP
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BU of 4alp by Molmil
The Lin28b Cold shock domain in complex with hexauridine
分子名称: GLYCEROL, HEXA URIDINE, LIN28 ISOFORM B
著者Mayr, F, Schuetz, A, Doege, N, Heinemann, U.
登録日2012-03-05
公開日2012-09-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献The Lin28 Cold-Shock Domain Remodels Pre-Let-7 Microrna.
Nucleic Acids Res., 40, 2012
4A4I
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BU of 4a4i by Molmil
Crystal structure of the human Lin28b cold shock domain
分子名称: GLYCEROL, PROTEIN LIN-28 HOMOLOG B, SULFATE ION
著者Mayr, F, Schuetz, A, Doege, N, Heinemann, U.
登録日2011-10-14
公開日2012-08-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Lin28 Cold-Shock Domain Remodels Pre-Let-7 Microrna.
Nucleic Acids Res., 40, 2012
4A75
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BU of 4a75 by Molmil
The Lin28b Cold shock domain in complex with hexathymidine.
分子名称: 5'-D(*TP*TP*TP*TP*TP*TP)-3', LIN28 COLD SHOCK DOMAIN, THIOCYANATE ION
著者Mayr, F, Schuetz, A, Doege, N, Heinemann, U.
登録日2011-11-11
公開日2012-09-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The Lin28 Cold-Shock Domain Remodels Pre-Let-7 Microrna.
Nucleic Acids Res., 40, 2012
4A76
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BU of 4a76 by Molmil
The Lin28b Cold shock domain in complex with heptathymidine
分子名称: 5'-D(*TP*TP*TP*TP*TP*TP*TP)-3', LIN28 COLD SHOCK DOMAIN
著者Mayr, F, Schuetz, A, Doege, N, Heinemann, U.
登録日2011-11-11
公開日2012-09-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献The Lin28 Cold-Shock Domain Remodels Pre-Let-7 Microrna.
Nucleic Acids Res., 40, 2012
2WBS
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BU of 2wbs by Molmil
Crystal structure of the zinc finger domain of Klf4 bound to its target DNA
分子名称: 5'-D(*GP*AP*GP*GP*CP*GP*CP)-3', 5'-D(*GP*CP*GP*CP*CP*TP*CP)-3', GLYCEROL, ...
著者Zocher, G, Schuetz, A, Carstanjen, D, Heinemann, U.
登録日2009-03-03
公開日2010-04-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Structure of the Klf4 DNA-Binding Domain Links to Self-Renewal and Macrophage Differentiation.
Cell.Mol.Life Sci., 68, 2011
3ZM3
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BU of 3zm3 by Molmil
Catalytic domain of human SHP2
分子名称: TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11
著者Bohm, K, Schuetz, A, Roske, Y, Heinemann, U.
登録日2013-02-04
公開日2014-04-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Selective Inhibitors of the Protein Tyrosine Phosphatase Shp2 Block Cellular Motility and Growth of Cancer Cells in Vitro and in Vivo.
Chemmedchem, 10, 2015
3ZM1
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BU of 3zm1 by Molmil
Catalytic domain of human SHP2
分子名称: TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11
著者Bohm, K, Schuetz, A, Roske, Y, Heinemann, U.
登録日2013-02-04
公開日2014-04-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Selective Inhibitors of the Protein Tyrosine Phosphatase Shp2 Block Cellular Motility and Growth of Cancer Cells in Vitro and in Vivo.
Chemmedchem, 10, 2015
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