2A59
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![BU of 2a59 by Molmil](/molmil-images/mine/2a59) | Structure of 6,7-Dimethyl-8-ribityllumazine synthase from Schizosaccharomyces pombe mutant W27Y with bound ligand 5-nitroso-6-ribitylamino-2,4(1H,3H)-pyrimidinedione | 分子名称: | 5-NITROSO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE, 6,7-dimethyl-8-ribityllumazine synthase, PHOSPHATE ION | 著者 | Koch, M, Breithaupt, C, Gerhardt, S, Haase, I, Weber, S, Cushman, M, Huber, R, Bacher, A, Fischer, M. | 登録日 | 2005-06-30 | 公開日 | 2005-07-19 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis of charge transfer complex formation by riboflavin bound to 6,7-dimethyl-8-ribityllumazine synthase Eur.J.Biochem., 271, 2004
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1JK3
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![BU of 1jk3 by Molmil](/molmil-images/mine/1jk3) | Crystal structure of human MMP-12 (Macrophage Elastase) at true atomic resolution | 分子名称: | 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, CALCIUM ION, MACROPHAGE METALLOELASTASE, ... | 著者 | Lang, R, Kocourek, A, Braun, M, Tschesche, H, Huber, R, Bode, W, Maskos, K. | 登録日 | 2001-07-11 | 公開日 | 2001-09-28 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | 主引用文献 | Substrate specificity determinants of human macrophage elastase (MMP-12) based on the 1.1 A crystal structure. J.Mol.Biol., 312, 2001
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1MVN
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![BU of 1mvn by Molmil](/molmil-images/mine/1mvn) | PPC decarboxylase mutant C175S complexed with pantothenoylaminoethenethiol | 分子名称: | 2,4-DIHYDROXY-N-[2-(2-MERCAPTO-VINYLCARBAMOYL)-ETHYL]-3,3-DIMETHYL-BUTYRAMIDE, FLAVIN MONONUCLEOTIDE, PPC decarboxylase AtHAL3a | 著者 | Steinbacher, S, Hernandez-Acosta, P, Bieseler, B, Blaesse, M, Huber, R, Culianez-Macia, F.A, Kupke, T. | 登録日 | 2002-09-26 | 公開日 | 2003-03-04 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Crystal Structure of the Plant PPC Decarboxylase AtHAL3a Complexed with an Ene-thiol Reaction Intermediate J.Mol.Biol., 327, 2003
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1P8J
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![BU of 1p8j by Molmil](/molmil-images/mine/1p8j) | CRYSTAL STRUCTURE OF THE PROPROTEIN CONVERTASE FURIN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR, ... | 著者 | Henrich, S, Cameron, A, Bourenkov, G.P, Kiefersauer, R, Huber, R, Lindberg, I, Bode, W, Than, M.E. | 登録日 | 2003-05-07 | 公開日 | 2003-07-08 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The Crystal Structure of the Proprotein Processing Proteinase Furin Explains its Stringent Specificity Nat.Struct.Biol., 10, 2003
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2F9P
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![BU of 2f9p by Molmil](/molmil-images/mine/2f9p) | Crystal Structure of the Recombinant Human Alpha I Tryptase Mutant D216G in Complex with Leupeptin | 分子名称: | (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Leupeptin, ... | 著者 | Rohr, K.B, Selwood, T, Marquardt, U, Huber, R, Schechter, N.M, Bode, W, Than, M.E. | 登録日 | 2005-12-06 | 公開日 | 2006-01-31 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | X-ray Structures of Free and Leupeptin-complexed Human alpha I-Tryptase Mutants: Indication for an alpha to beta-Tryptase Transition J.Mol.Biol., 357, 2005
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1FIU
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![BU of 1fiu by Molmil](/molmil-images/mine/1fiu) | TETRAMERIC RESTRICTION ENDONUCLEASE NGOMIV IN COMPLEX WITH CLEAVED DNA | 分子名称: | ACETIC ACID, DNA (5'-D(*TP*GP*CP*G)-3'), DNA (5'-D(P*CP*CP*GP*GP*CP*GP*C)-3'), ... | 著者 | Deibert, M, Grazulis, S, Sasnauskas, G, Siksnys, V, Huber, R. | 登録日 | 2000-08-07 | 公開日 | 2001-02-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of the tetrameric restriction endonuclease NgoMIV in complex with cleaved DNA. Nat.Struct.Biol., 7, 2000
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1MVL
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![BU of 1mvl by Molmil](/molmil-images/mine/1mvl) | PPC decarboxylase mutant C175S | 分子名称: | FLAVIN MONONUCLEOTIDE, PPC decarboxylase AtHAL3a | 著者 | Steinbacher, S, Hernandez-Acosta, P, Bieseler, B, Blaesse, M, Huber, R, Culianez-Macia, F.A, Kupke, T. | 登録日 | 2002-09-26 | 公開日 | 2003-03-04 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of the Plant PPC Decarboxylase AtHAL3a Complexed with an Ene-thiol Reaction Intermediate J.Mol.Biol., 327, 2003
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1NPS
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![BU of 1nps by Molmil](/molmil-images/mine/1nps) | CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF PROTEIN S | 分子名称: | CALCIUM ION, DEVELOPMENT-SPECIFIC PROTEIN S | 著者 | Wenk, M, Baumgartner, R, Mayer, E.M, Huber, R, Holak, T.A, Jaenicke, R. | 登録日 | 1999-02-01 | 公開日 | 2000-02-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The domains of protein S from Myxococcus xanthus: structure, stability and interactions. J.Mol.Biol., 286, 1999
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1REI
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![BU of 1rei by Molmil](/molmil-images/mine/1rei) | THE MOLECULAR STRUCTURE OF A DIMER COMPOSED OF THE VARIABLE PORTIONS OF THE BENCE-JONES PROTEIN REI REFINED AT 2.0 ANGSTROMS RESOLUTION | 分子名称: | BENCE-JONES PROTEIN REI (LIGHT CHAIN) | 著者 | Epp, O, Lattman, E.E, Colman, P, Fehlhammer, H, Bode, W, Schiffer, M, Huber, R, Palm, W. | 登録日 | 1976-03-17 | 公開日 | 1976-05-19 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The molecular structure of a dimer composed of the variable portions of the Bence-Jones protein REI refined at 2.0-A resolution. Biochemistry, 14, 1975
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1KLO
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![BU of 1klo by Molmil](/molmil-images/mine/1klo) | |
2C1L
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![BU of 2c1l by Molmil](/molmil-images/mine/2c1l) | Structure of the BfiI restriction endonuclease | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BICARBONATE ION, ... | 著者 | Grazulis, S, Manakova, E, Roessle, M, Bochtler, M, Tamulaitiene, G, Huber, R, Siksnys, V. | 登録日 | 2005-09-15 | 公開日 | 2005-10-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of the Metal-Independent Restriction Enzyme Bfii Reveals Fusion of a Specific DNA-Binding Domain with a Nonspecific Nuclease. Proc.Natl.Acad.Sci.USA, 102, 2005
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2F9N
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![BU of 2f9n by Molmil](/molmil-images/mine/2f9n) | Crystal Structure of the Recombinant Human Alpha I Tryptase Mutant K192Q/D216G in Complex with Leupeptin | 分子名称: | (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Leupeptin, ... | 著者 | Rohr, K.B, Selwood, T, Marquardt, U, Huber, R, Schechter, N.M, Bode, W, Than, M.E. | 登録日 | 2005-12-06 | 公開日 | 2006-01-31 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | X-ray Structures of Free and Leupeptin-complexed Human alpha I-Tryptase Mutants: Indication for an alpha to beta-Tryptase Transition J.Mol.Biol., 357, 2005
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1PMA
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![BU of 1pma by Molmil](/molmil-images/mine/1pma) | PROTEASOME FROM THERMOPLASMA ACIDOPHILUM | 分子名称: | PROTEASOME | 著者 | Loewe, J, Stock, D, Jap, B, Zwickl, P, Baumeister, W, Huber, R. | 登録日 | 1994-12-19 | 公開日 | 1996-06-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution. Science, 268, 1995
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4M90
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![BU of 4m90 by Molmil](/molmil-images/mine/4m90) | crystal structure of oxidized hN33/Tusc3 | 分子名称: | Tumor suppressor candidate 3 | 著者 | Mohorko, E, Owen, R.L, Malojcic, G, Brozzo, M.S, Aebi, M, Glockshuber, R. | 登録日 | 2013-08-14 | 公開日 | 2014-03-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural basis of substrate specificity of human oligosaccharyl transferase subunit n33/tusc3 and its role in regulating protein N-glycosylation. Structure, 22, 2014
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4M8G
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![BU of 4m8g by Molmil](/molmil-images/mine/4m8g) | Crystal structure of Se-Met hN33/Tusc3 | 分子名称: | Tumor suppressor candidate 3 | 著者 | Mohorko, E, Owen, R.L, Malojcic, G, Brozzo, M.S, Aebi, M, Glockshuber, R. | 登録日 | 2013-08-13 | 公開日 | 2014-03-26 | 最終更新日 | 2014-05-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis of substrate specificity of human oligosaccharyl transferase subunit n33/tusc3 and its role in regulating protein N-glycosylation. Structure, 22, 2014
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1U7Z
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![BU of 1u7z by Molmil](/molmil-images/mine/1u7z) | Phosphopantothenoylcysteine synthetase from E. coli, 4'-phosphopantothenoyl-CMP complex | 分子名称: | Coenzyme A biosynthesis bifunctional protein coaBC, PHOSPHORIC ACID MONO-[3-(3-{[5-(4-AMINO-2-OXO-2H-PYRIMIDIN-1-YL)-3,4- DIHYDROXY-TETRAHYDRO-FURAN-2- YLMETHOXY]-HYDROXY-PHOSPHORYLOXY}-3-OXO-PROPYLCARBAMOYL)-3-HYDROXY-2,2- DIMETHYL-PROPYL] ESTER | 著者 | Stanitzek, S, Augustin, M.A, Huber, R, Kupke, T, Steinbacher, S. | 登録日 | 2004-08-04 | 公開日 | 2004-11-30 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Basis of CTP-Dependent Peptide Bond Formation in Coenzyme A Biosynthesis Catalyzed by Escherichia coli PPC Synthetase STRUCTURE, 12, 2004
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1U7U
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![BU of 1u7u by Molmil](/molmil-images/mine/1u7u) | Phosphopantothenoylcysteine synthetase from E. coli | 分子名称: | Coenzyme A biosynthesis bifunctional protein coaBC | 著者 | Stanitzek, S, Augustin, M.A, Huber, R, Kupke, T, Steinbacher, S. | 登録日 | 2004-08-04 | 公開日 | 2004-11-30 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural Basis of CTP-Dependent Peptide Bond Formation in Coenzyme A Biosynthesis Catalyzed by Escherichia coli PPC Synthetase STRUCTURE, 12, 2004
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1U80
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![BU of 1u80 by Molmil](/molmil-images/mine/1u80) | Phosphopantothenoylcysteine synthetase from E. coli, CMP complex | 分子名称: | CYTIDINE-5'-MONOPHOSPHATE, Coenzyme A biosynthesis bifunctional protein coaBC, PHOSPHATE ION | 著者 | Stanitzek, S, Augustin, M.A, Huber, R, Kupke, T, Steinbacher, S. | 登録日 | 2004-08-04 | 公開日 | 2004-11-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural Basis of CTP-Dependent Peptide Bond Formation in Coenzyme A Biosynthesis Catalyzed by Escherichia coli PPC Synthetase STRUCTURE, 12, 2004
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2DSP
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![BU of 2dsp by Molmil](/molmil-images/mine/2dsp) | Structural Basis for the Inhibition of Insulin-like Growth Factors by IGF Binding Proteins | 分子名称: | Insulin-like growth factor IB, Insulin-like growth factor-binding protein 4 | 著者 | Sitar, T, Popowicz, G.M, Siwanowicz, I, Huber, R, Holak, T.A. | 登録日 | 2006-07-05 | 公開日 | 2006-08-22 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins. Proc.Natl.Acad.Sci.Usa, 103, 2006
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1N3S
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![BU of 1n3s by Molmil](/molmil-images/mine/1n3s) | Biosynthesis of pteridins. Reaction mechanism of GTP cyclohydrolase I | 分子名称: | GTP cyclohydrolase I, GUANOSINE-5'-TRIPHOSPHATE | 著者 | Rebelo, J, Auerbach, G, Bader, G, Bracher, A, Nar, H, Hoesl, C, Schramek, N, Kaiser, J, Bacher, A, Huber, R, Fischer, M. | 登録日 | 2002-10-29 | 公開日 | 2004-03-02 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Biosynthesis of Pteridines. Reaction Mechanism of GTP Cyclohydrolase I J.MOL.BIOL., 326, 2003
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1N3T
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![BU of 1n3t by Molmil](/molmil-images/mine/1n3t) | Biosynthesis of pteridins. Reaction mechanism of GTP cyclohydrolase I | 分子名称: | GTP cyclohydrolase I, GUANOSINE-5'-TRIPHOSPHATE | 著者 | Rebelo, J, Auerbach, G, Bader, G, Bracher, A, Nar, H, Hoesl, C, Schramek, N, Kaiser, J, Bacher, A, Huber, R, Fischer, M. | 登録日 | 2002-10-29 | 公開日 | 2003-10-14 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Biosynthesis of Pteridines. Reaction Mechanism of GTP Cyclohydrolase I J.MOL.BIOL., 326, 2003
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1Q8T
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![BU of 1q8t by Molmil](/molmil-images/mine/1q8t) | The Catalytic Subunit of cAMP-dependent Protein Kinase (PKA) in Complex with Rho-kinase Inhibitor Y-27632 | 分子名称: | (R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE, cAMP-dependent protein kinase inhibitor, alpha form, ... | 著者 | Breitenlechner, C, Gassel, M, Hidaka, H, Kinzel, V, Huber, R, Engh, R.A, Bossemeyer, D. | 登録日 | 2003-08-22 | 公開日 | 2003-12-16 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity. Structure, 11, 2003
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2AZN
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![BU of 2azn by Molmil](/molmil-images/mine/2azn) | X-RAY Structure of 2,5-diamino-6-ribosylamino-4(3h)-pyrimidinone 5-phosphate reductase | 分子名称: | 2-(6-(2-CYCLOHEXYLETHOXY)-TETRAHYDRO-4,5-DIHYDROXY-2(HYDROXYMETHYL)-2H-PYRAN-3-YLOXY)-TETRAHYDRO-6(HYDROXYMETHYL)-2H-PYRAN-3,4,5-TRIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Chatwell, L, Bacher, A, Huber, R, Fischer, M, Krojer, T. | 登録日 | 2005-09-12 | 公開日 | 2006-08-29 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Biosynthesis of riboflavin: structure and properties of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase of Methanocaldococcus jannaschii J.Mol.Biol., 359, 2006
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1I41
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![BU of 1i41 by Molmil](/molmil-images/mine/1i41) | CYSTATHIONINE GAMMA-SYNTHASE IN COMPLEX WITH THE INHIBITOR APPA | 分子名称: | 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-IMINO]-5-PHOSPHONO-PENT-3-ENOIC ACID, CYSTATHIONINE GAMMA-SYNTHASE | 著者 | Steegborn, C, Laber, B, Messerschmidt, A, Huber, R, Clausen, T. | 登録日 | 2001-02-19 | 公開日 | 2001-09-05 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor. J.Mol.Biol., 311, 2001
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1I43
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![BU of 1i43 by Molmil](/molmil-images/mine/1i43) | CYSTATHIONINE GAMMA-SYNTHASE IN COMPLEX WITH THE INHIBITOR PPCA | 分子名称: | 3-(PHOSPHONOMETHYL)PYRIDINE-2-CARBOXYLIC ACID, CYSTATHIONINE GAMMA-SYNTHASE, PYRIDOXAL-5'-PHOSPHATE | 著者 | Steegborn, C, Laber, B, Messerschmidt, A, Huber, R, Clausen, T. | 登録日 | 2001-02-19 | 公開日 | 2001-09-05 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor. J.Mol.Biol., 311, 2001
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