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PDB: 160 results

3CXW
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BU of 3cxw by Molmil
Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a beta carboline ligand I
Descriptor: (4R)-7,8-dichloro-1',9-dimethyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile, CHLORIDE ION, Pimtide peptide, ...
Authors:Filippakopoulos, P, Bullock, A, Fedorov, O, Huber, K, Bracher, F, Pike, A.C.W, Roos, A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2008-04-25
Release date:2008-07-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:7,8-Dichloro-1-oxo-beta-carbolines as a Versatile Scaffold for the Development of Potent and Selective Kinase Inhibitors with Unusual Binding Modes
J.Med.Chem., 55, 2012
3CY2
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BU of 3cy2 by Molmil
Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a beta carboline ligand II
Descriptor: (4R)-7-chloro-9-methyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile, 1,2-ETHANEDIOL, CHLORIDE ION, ...
Authors:Filippakopoulos, P, Bullock, A, Fedorov, O, Huber, K, Bracher, F, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2008-04-25
Release date:2008-07-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:7,8-Dichloro-1-oxo-beta-carbolines as a Versatile Scaffold for the Development of Potent and Selective Kinase Inhibitors with Unusual Binding Modes
J.Med.Chem., 55, 2012
2WU7
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BU of 2wu7 by Molmil
Crystal Structure of the Human CLK3 in complex with V25
Descriptor: CHLORIDE ION, DUAL SPECIFICITY PROTEIN KINASE CLK3, SULFATE ION, ...
Authors:Muniz, J.R.C, Fedorov, O, King, O, Filippakopoulos, P, Bullock, A.N, Phillips, C, Heightman, T, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Bracher, F, Huber, K, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S.
Deposit date:2009-09-30
Release date:2009-10-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Specific Clk Inhibitors from a Novel Chemotype for Regulation of Alternative Splicing.
Chem.Biol, 18, 2011
3BHY
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BU of 3bhy by Molmil
Crystal structure of human death associated protein kinase 3 (DAPK3) in complex with a beta-carboline ligand
Descriptor: (4R)-7,8-dichloro-1',9-dimethyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile, CHLORIDE ION, Death-associated protein kinase 3
Authors:Filippakopoulos, P, Rellos, P, Eswaran, J, Fedorov, O, Berridge, G, Niesen, F, Bracher, F, Huber, K, Pike, A.C.W, Roos, A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2007-11-29
Release date:2007-12-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:7,8-dichloro-1-oxo-beta-carbolines as a versatile scaffold for the development of potent and selective kinase inhibitors with unusual binding modes.
J.Med.Chem., 55, 2012
5T3P
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BU of 5t3p by Molmil
Crystal structure of Human Peroxisomal coenzyme A diphosphatase NUDT7
Descriptor: 1,2-ETHANEDIOL, Peroxisomal coenzyme A diphosphatase NUDT7
Authors:Srikannathasan, V, Nunez, C.A, Tallant, C, Siejka, P, Mathea, S, Kopec, J, Elkins, J.M, Burgess-Brown, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F, Huber, K.
Deposit date:2016-08-26
Release date:2017-09-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Crystal structure of Human Peroxisomal coenzyme A diphosphatase NUDT7
To Be Published
7NQH
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BU of 7nqh by Molmil
55S mammalian mitochondrial ribosome with mtRF1a and P-site tRNAMet
Descriptor: 12S rRNA, 16S rRNA, 28S ribosomal protein S16, ...
Authors:Kummer, E, Schubert, K, Ban, N.
Deposit date:2021-03-01
Release date:2021-05-05
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.
Mol.Cell, 81, 2021
7NQL
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BU of 7nql by Molmil
55S mammalian mitochondrial ribosome with ICT1 and P site tRNAMet
Descriptor: 12S rRNA, 16S rRNA, 28S ribosomal protein S16, ...
Authors:Kummer, E, Schubert, K, Ban, N.
Deposit date:2021-03-01
Release date:2021-05-05
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.
Mol.Cell, 81, 2021
7NSJ
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BU of 7nsj by Molmil
55S mammalian mitochondrial ribosome with tRNA(P/P) and tRNA(E*)
Descriptor: 12S rRNA, 16S rRNA, 28S ribosomal protein S16, ...
Authors:Kummer, E, Schubert, K, Ban, N.
Deposit date:2021-03-07
Release date:2021-06-02
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.
Mol.Cell, 81, 2021
7NSI
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BU of 7nsi by Molmil
55S mammalian mitochondrial ribosome with mtRRF (pre) and tRNA(P/E)
Descriptor: 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ...
Authors:Kummer, E, Schubert, K, Ban, N.
Deposit date:2021-03-07
Release date:2021-06-02
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.
Mol.Cell, 81, 2021
7NSH
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BU of 7nsh by Molmil
39S mammalian mitochondrial large ribosomal subunit with mtRRF (post) and mtEFG2
Descriptor: 16S rRNA, 39S ribosomal protein L48, mitochondrial, ...
Authors:Kummer, E, Schubert, K, Ban, N.
Deposit date:2021-03-07
Release date:2021-05-05
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.
Mol.Cell, 81, 2021

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건을2024-11-20부터공개중

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