1JCT
 
 | | Glucarate Dehydratase, N341L mutant Orthorhombic Form | | Descriptor: | D-GLUCARATE, Glucarate Dehydratase, ISOPROPYL ALCOHOL, ... | | Authors: | Gulick, A.M, Hubbard, B.K, Gerlt, J.A, Rayment, I. | | Deposit date: | 2001-06-11 | | Release date: | 2001-09-05 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Evolution of enzymatic activities in the enolase superfamily: identification of the general acid catalyst in the active site of D-glucarate dehydratase from Escherichia coli.
Biochemistry, 40, 2001
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1JDF
 | | Glucarate Dehydratase from E.coli N341D mutant | | Descriptor: | 2,3-DIHYDROXY-5-OXO-HEXANEDIOATE, Glucarate Dehydratase, ISOPROPYL ALCOHOL, ... | | Authors: | Gulick, A.M, Hubbard, B.K, Gerlt, J.A, Rayment, I. | | Deposit date: | 2001-06-13 | | Release date: | 2001-09-05 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Evolution of enzymatic activities in the enolase superfamily: identification of the general acid catalyst in the active site of D-glucarate dehydratase from Escherichia coli.
Biochemistry, 40, 2001
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3CXO
 | | Crystal structure of L-rhamnonate dehydratase from Salmonella typhimurium complexed with Mg and 3-deoxy-L-rhamnonate | | Descriptor: | (2R,4S)-2,4,7-trihydroxyheptanoic acid, 3,6-dideoxy-L-arabino-hexonic acid, MAGNESIUM ION, ... | | Authors: | Fedorov, A.A, Fedorov, E.V, Rakus, J.F, Hubbard, B.K, Gerlt, J.A, Almo, S.C. | | Deposit date: | 2008-04-24 | | Release date: | 2008-09-23 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Evolution of enzymatic activities in the enolase superfamily: L-rhamnonate dehydratase.
Biochemistry, 47, 2008
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4WGI
 | | A Single Diastereomer of a Macrolactam Core Binds Specifically to Myeloid Cell Leukemia 1 (MCL1) | | Descriptor: | (2S)-2-[(2S,3R)-10-{[(4-fluorophenyl)sulfonyl]amino}-3-methyl-2-[(methyl{[4-(trifluoromethyl)phenyl]carbamoyl}amino)methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-5(6H)-yl]propanoic acid, FORMIC ACID, MAGNESIUM ION, ... | | Authors: | Clifton, M.C, Fairman, J.W, Fang, C, D'Souza, B, Fulroth, B, Leed, A, McCarren, P, Wang, L, Wang, Y, Kaushik, V, Palmer, M, Wei, G, Golub, T.R, Hubbard, B.K, Serrano-Wu, M.H. | | Deposit date: | 2014-09-18 | | Release date: | 2014-11-19 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Single Diastereomer of a Macrolactam Core Binds Specifically to Myeloid Cell Leukemia 1 (MCL1).
Acs Med.Chem.Lett., 5, 2014
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1ECQ
 | | E. COLI GLUCARATE DEHYDRATASE BOUND TO 4-DEOXYGLUCARATE | | Descriptor: | 4-DEOXYGLUCARATE, GLUCARATE DEHYDRATASE, ISOPROPYL ALCOHOL, ... | | Authors: | Gulick, A.M, Hubbard, B.K, Gerlt, J.A, Rayment, I. | | Deposit date: | 2000-01-25 | | Release date: | 2000-05-23 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Evolution of enzymatic activities in the enolase superfamily: crystallographic and mutagenesis studies of the reaction catalyzed by D-glucarate dehydratase from Escherichia coli.
Biochemistry, 39, 2000
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1EC7
 | | E. COLI GLUCARATE DEHYDRATASE NATIVE ENZYME | | Descriptor: | GLUCARATE DEHYDRATASE, ISOPROPYL ALCOHOL, MAGNESIUM ION | | Authors: | Gulick, A.M, Hubbard, B.K, Gerlt, J.A, Rayment, I. | | Deposit date: | 2000-01-25 | | Release date: | 2000-05-23 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Evolution of enzymatic activities in the enolase superfamily: crystallographic and mutagenesis studies of the reaction catalyzed by D-glucarate dehydratase from Escherichia coli.
Biochemistry, 39, 2000
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1EC8
 | | E. COLI GLUCARATE DEHYDRATASE BOUND TO PRODUCT 2,3-DIHYDROXY-5-OXO-HEXANEDIOATE | | Descriptor: | 2,3-DIHYDROXY-5-OXO-HEXANEDIOATE, GLUCARATE DEHYDRATASE, ISOPROPYL ALCOHOL, ... | | Authors: | Gulick, A.M, Hubbard, B.K, Gerlt, J.A, Rayment, I. | | Deposit date: | 2000-01-25 | | Release date: | 2000-05-23 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Evolution of enzymatic activities in the enolase superfamily: crystallographic and mutagenesis studies of the reaction catalyzed by D-glucarate dehydratase from Escherichia coli.
Biochemistry, 39, 2000
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1EC9
 | | E. COLI GLUCARATE DEHYDRATASE BOUND TO XYLAROHYDROXAMATE | | Descriptor: | GLUCARATE DEHYDRATASE, ISOPROPYL ALCOHOL, MAGNESIUM ION, ... | | Authors: | Gulick, A.M, Hubbard, B.K, Gerlt, J.A, Rayment, I. | | Deposit date: | 2000-01-25 | | Release date: | 2000-05-23 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Evolution of enzymatic activities in the enolase superfamily: crystallographic and mutagenesis studies of the reaction catalyzed by D-glucarate dehydratase from Escherichia coli.
Biochemistry, 39, 2000
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