1EC8

E. COLI GLUCARATE DEHYDRATASE BOUND TO PRODUCT 2,3-DIHYDROXY-5-OXO-HEXANEDIOATE

Summary for 1EC8

Entry DOI	10.2210/pdb1ec8/pdb
Related	1BQG 1EC7 1EC9 1ECQ
Descriptor	GLUCARATE DEHYDRATASE, MAGNESIUM ION, 2,3-DIHYDROXY-5-OXO-HEXANEDIOATE, ... (5 entities in total)
Functional Keywords	glucarate dehydratase enolase enzyme superfamily tim barrel (beta/alpha)7beta barrel, lyase
Biological source	Escherichia coli
Total number of polymer chains	4
Total formula weight	197885.45
Authors	Gulick, A.M.,Hubbard, B.K.,Gerlt, J.A.,Rayment, I. (deposition date: 2000-01-25, release date: 2000-05-23, Last modification date: 2024-03-13)
Primary citation	Gulick, A.M.,Hubbard, B.K.,Gerlt, J.A.,Rayment, I. Evolution of enzymatic activities in the enolase superfamily: crystallographic and mutagenesis studies of the reaction catalyzed by D-glucarate dehydratase from Escherichia coli. Biochemistry, 39:4590-4602, 2000 Cited by PubMed: 10769114 DOI: 10.1021/bi992782i PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation