3S1N
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![BU of 3s1n by Molmil](/molmil-images/mine/3s1n) | RNA Polymerase II Initiation Complex with a 5-nt RNA (variant 2) | 分子名称: | DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*GP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | 著者 | Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. | 登録日 | 2011-05-15 | 公開日 | 2011-08-10 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Initiation complex structure and promoter proofreading. Science, 333, 2011
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3S2D
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![BU of 3s2d by Molmil](/molmil-images/mine/3s2d) | RNA Polymerase II Initiation Complex with a 5-nt RNA containing a 5Br-U | 分子名称: | DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*AP*CP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | 著者 | Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. | 登録日 | 2011-05-16 | 公開日 | 2011-08-10 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Initiation complex structure and promoter proofreading. Science, 333, 2011
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3S1Q
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![BU of 3s1q by Molmil](/molmil-images/mine/3s1q) | RNA Polymerase II Initiation Complex with a 5-nt 3'-deoxy RNA soaked with ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. | 登録日 | 2011-05-16 | 公開日 | 2011-08-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Initiation complex structure and promoter proofreading. Science, 333, 2011
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3S15
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![BU of 3s15 by Molmil](/molmil-images/mine/3s15) | RNA Polymerase II Initiation Complex with a 7-nt RNA | 分子名称: | DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | 著者 | Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. | 登録日 | 2011-05-14 | 公開日 | 2011-08-10 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Initiation complex structure and promoter proofreading. Science, 333, 2011
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3S2H
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![BU of 3s2h by Molmil](/molmil-images/mine/3s2h) | RNA Polymerase II Initiation Complex with a 6-nt RNA containing a 2[prime]-iodo ATP | 分子名称: | DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | 著者 | Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. | 登録日 | 2011-05-16 | 公開日 | 2011-08-17 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Initiation complex structure and promoter proofreading. Science, 333, 2011
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3RZD
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![BU of 3rzd by Molmil](/molmil-images/mine/3rzd) | RNA Polymerase II Initiation Complex with a 5-nt RNA | 分子名称: | DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | 著者 | Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. | 登録日 | 2011-05-11 | 公開日 | 2011-08-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Initiation complex structure and promoter proofreading. Science, 333, 2011
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3RZO
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![BU of 3rzo by Molmil](/molmil-images/mine/3rzo) | RNA Polymerase II Initiation Complex with a 4-nt RNA | 分子名称: | DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | 著者 | Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. | 登録日 | 2011-05-12 | 公開日 | 2011-08-10 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Initiation complex structure and promoter proofreading. Science, 333, 2011
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6BK4
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![BU of 6bk4 by Molmil](/molmil-images/mine/6bk4) | |
3J6Q
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![BU of 3j6q by Molmil](/molmil-images/mine/3j6q) | Identification of the active sites in the methyltransferases of a transcribing dsRNA virus | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, Structural protein VP3 | 著者 | Zhu, B, Yang, C, Liu, H, Cheng, L, Song, F, Zeng, S, Huang, X, Ji, G, Zhu, P. | 登録日 | 2014-03-20 | 公開日 | 2014-10-08 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Identification of the active sites in the methyltransferases of a transcribing dsRNA virus. J.Mol.Biol., 426, 2014
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3S17
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![BU of 3s17 by Molmil](/molmil-images/mine/3s17) | RNA Polymerase II Initiation Complex with a 9-nt RNA | 分子名称: | DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | 著者 | Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. | 登録日 | 2011-05-14 | 公開日 | 2011-08-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Initiation complex structure and promoter proofreading. Science, 333, 2011
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3S1M
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![BU of 3s1m by Molmil](/molmil-images/mine/3s1m) | RNA Polymerase II Initiation Complex with a 5-nt RNA (variant 1) | 分子名称: | DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*GP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | 著者 | Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. | 登録日 | 2011-05-15 | 公開日 | 2011-08-10 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.13 Å) | 主引用文献 | Initiation complex structure and promoter proofreading. Science, 333, 2011
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5DQC
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![BU of 5dqc by Molmil](/molmil-images/mine/5dqc) | Co-crystal of BACE1 with compound 0211 | 分子名称: | Beta-secretase 1, N-[(2S,3R)-3-hydroxy-4-({(2S,3S)-3-hydroxy-1-[(2-methylpropyl)amino]-1-oxobutan-2-yl}amino)-1-phenylbutan-2-yl]-5-[methyl(methylsulfonyl)amino]-N'-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide | 著者 | Ghosh, A.K, Bhavanam, S.R, Yen, T.-C, Cardenas, E.L, Rao, K.V, Downs, D, Huang, X, Tang, J, Mescar, A.D. | 登録日 | 2015-09-14 | 公開日 | 2016-02-17 | 最終更新日 | 2016-07-13 | 実験手法 | X-RAY DIFFRACTION (2.4651 Å) | 主引用文献 | Design of Potent and Highly Selective Inhibitors for Human beta-Secretase 2 (Memapsin 1), a Target for Type 2 Diabetes. Chem Sci, 7, 2016
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6J8E
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![BU of 6j8e by Molmil](/molmil-images/mine/6j8e) | Human Nav1.2-beta2-KIIIA ternary complex | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Pan, X, Li, Z, Huang, X, Huang, G, Yan, N. | 登録日 | 2019-01-18 | 公開日 | 2019-02-27 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Molecular basis for pore blockade of human Na+channel Nav1.2 by the mu-conotoxin KIIIA. Science, 363, 2019
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4HNM
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![BU of 4hnm by Molmil](/molmil-images/mine/4hnm) | Crystal structure of human catenin-beta-like 1 56 kDa fragment | 分子名称: | Beta-catenin-like protein 1 | 著者 | Du, Z, Huang, X, Wang, G, Wu, Y. | 登録日 | 2012-10-19 | 公開日 | 2013-07-31 | 最終更新日 | 2013-08-21 | 実験手法 | X-RAY DIFFRACTION (2.9001 Å) | 主引用文献 | The structure of full-length human CTNNBL1 reveals a distinct member of the armadillo-repeat protein family. Acta Crystallogr.,Sect.D, 69, 2013
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4HM9
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![BU of 4hm9 by Molmil](/molmil-images/mine/4hm9) | Crystal structure of full-length human catenin-beta-like 1 | 分子名称: | Beta-catenin-like protein 1 | 著者 | Du, Z, Huang, X, Wang, G, Wu, Y. | 登録日 | 2012-10-18 | 公開日 | 2013-07-31 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.1001 Å) | 主引用文献 | The structure of full-length human CTNNBL1 reveals a distinct member of the armadillo-repeat protein family. Acta Crystallogr.,Sect.D, 69, 2013
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4JKV
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![BU of 4jkv by Molmil](/molmil-images/mine/4jkv) | Structure of the human smoothened 7TM receptor in complex with an antitumor agent | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-fluoro-N-methyl-N-{1-[4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl]piperidin-4-yl}-2-(trifluoromethyl)benzamide, DI(HYDROXYETHYL)ETHER, ... | 著者 | Wang, C, Wu, H, Katritch, V, Han, G.W, Huang, X, Liu, W, Siu, F.Y, Roth, B.L, Cherezov, V, Stevens, R.C, GPCR Network (GPCR) | 登録日 | 2013-03-11 | 公開日 | 2013-04-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structure of the human smoothened receptor bound to an antitumour agent. Nature, 497, 2013
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4IB4
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![BU of 4ib4 by Molmil](/molmil-images/mine/4ib4) | Crystal structure of the chimeric protein of 5-HT2B-BRIL in complex with ergotamine | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHOLESTEROL, ... | 著者 | Wacker, D, Wang, C, Katritch, V, Han, G.W, Huang, X, Vardy, E, McCorvy, J.D, Jiang, Y, Chu, M, Siu, F.Y, Liu, W, Xu, H.E, Cherezov, V, Roth, B.L, Stevens, R.C, GPCR Network (GPCR) | 登録日 | 2012-12-07 | 公開日 | 2013-03-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural features for functional selectivity at serotonin receptors. Science, 340, 2013
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4H0B
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![BU of 4h0b by Molmil](/molmil-images/mine/4h0b) | Complex of G65T Myoglobin with DMSO in its Distal Cavity | 分子名称: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Myoglobin, ... | 著者 | Lebioda, L, Lovelace, L.L, Celeste, L.R, Huang, X, Wang, C, Shengfang, S, Dawson, J.H. | 登録日 | 2012-09-07 | 公開日 | 2012-11-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Complex of myoglobin with phenol bound in a proximal cavity. Acta Crystallogr.,Sect.F, 68, 2012
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3SDN
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![BU of 3sdn by Molmil](/molmil-images/mine/3sdn) | Structure of G65I sperm whale myoglobin mutant | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Myoglobin, ... | 著者 | Lebioda, L, Huang, X. | 登録日 | 2011-06-09 | 公開日 | 2011-11-02 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Amphitrite ornata Dehaloperoxidase (DHP): Investigations of Structural Factors That Influence the Mechanism of Halophenol Dehalogenation Using "Peroxidase-like" Myoglobin Mutants and "Myoglobin-like" DHP Mutants. Biochemistry, 50, 2011
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7WFW
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![BU of 7wfw by Molmil](/molmil-images/mine/7wfw) | Apo human Nav1.8 | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yan, N, Pan, X.J, Huang, X.S, Huang, G.X. | 登録日 | 2021-12-27 | 公開日 | 2022-08-03 | 最終更新日 | 2022-09-21 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis for high-voltage activation and subtype-specific inhibition of human Na v 1.8. Proc.Natl.Acad.Sci.USA, 119, 2022
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7WFR
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![BU of 7wfr by Molmil](/molmil-images/mine/7wfr) | Human Nav1.8 with A-803467, class III | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yan, N, Pan, X.J, Huang, X.S, Huang, G.X. | 登録日 | 2021-12-27 | 公開日 | 2022-08-03 | 最終更新日 | 2022-09-21 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis for high-voltage activation and subtype-specific inhibition of human Na v 1.8. Proc.Natl.Acad.Sci.USA, 119, 2022
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7WEL
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![BU of 7wel by Molmil](/molmil-images/mine/7wel) | Human Nav1.8 with A-803467, class II | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yan, N, Pan, X.J, Huang, X.S, Huang, G.X. | 登録日 | 2021-12-23 | 公開日 | 2022-08-03 | 最終更新日 | 2022-09-21 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for high-voltage activation and subtype-specific inhibition of human Na v 1.8. Proc.Natl.Acad.Sci.USA, 119, 2022
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7WE4
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![BU of 7we4 by Molmil](/molmil-images/mine/7we4) | Human Nav1.8 with A-803467, class I | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yan, N, Pan, X.J, Huang, X.S, Huang, G.X. | 登録日 | 2021-12-22 | 公開日 | 2022-08-03 | 最終更新日 | 2022-09-21 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural basis for high-voltage activation and subtype-specific inhibition of human Na v 1.8. Proc.Natl.Acad.Sci.USA, 119, 2022
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3BPR
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![BU of 3bpr by Molmil](/molmil-images/mine/3bpr) | Crystal structure of catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor C52 | 分子名称: | 2-(2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE, CHLORIDE ION, Proto-oncogene tyrosine-protein kinase MER, ... | 著者 | Walker, J.R, Huang, X, Finerty Jr, P.J, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2007-12-19 | 公開日 | 2008-01-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural insights into the inhibited states of the Mer receptor tyrosine kinase. J.Struct.Biol., 165, 2009
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3BRB
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![BU of 3brb by Molmil](/molmil-images/mine/3brb) | Crystal structure of catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | 著者 | Walker, J.R, Huang, X, Finerty Jr, P.J, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2007-12-21 | 公開日 | 2008-01-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural insights into the inhibited states of the Mer receptor tyrosine kinase. J.Struct.Biol., 165, 2009
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