7CD9
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![BU of 7cd9 by Molmil](/molmil-images/mine/7cd9) | Crystal Structure of SETDB1 tudor domain in complexed with Compound 6 | Descriptor: | 3-methyl-2-[[(3R,5R)-1-methyl-5-(4-phenylmethoxyphenyl)piperidin-3-yl]amino]-5H-pyrrolo[3,2-d]pyrimidin-4-one, CITRIC ACID, Histone-lysine N-methyltransferase SETDB1 | Authors: | Xiong, L, Guo, Y, Mao, X, Huang, L, Wu, C, Yang, S. | Deposit date: | 2020-06-19 | Release date: | 2021-04-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure-Guided Discovery of a Potent and Selective Cell-Active Inhibitor of SETDB1 Tudor Domain. Angew.Chem.Int.Ed.Engl., 60, 2021
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5WE1
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![BU of 5we1 by Molmil](/molmil-images/mine/5we1) | Structural Basis for Shelterin Bridge Assembly | Descriptor: | Protection of telomeres protein poz1,Protection of telomeres protein poz1, Protection of telomeres protein tpz1, ZINC ION | Authors: | Kim, J.-K, Liu, J, Hu, X, Yu, C, Roskamp, K, Sankaran, B, Huang, L, Komives, E.-A, Qiao, F. | Deposit date: | 2017-07-06 | Release date: | 2017-12-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.202 Å) | Cite: | Structural Basis for Shelterin Bridge Assembly. Mol. Cell, 68, 2017
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4DL0
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![BU of 4dl0 by Molmil](/molmil-images/mine/4dl0) | Crystal Structure of the heterotrimeric EGChead Peripheral Stalk Complex of the Yeast Vacuolar ATPase | Descriptor: | SULFATE ION, TRIMETHYL LEAD ION, V-type proton ATPase subunit C, ... | Authors: | Oot, R.A, Huang, L.S, Berry, E.A, Wilkens, S. | Deposit date: | 2012-02-05 | Release date: | 2012-10-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.905 Å) | Cite: | Crystal Structure of the Yeast Vacuolar ATPase Heterotrimeric EGC(head) Peripheral Stalk Complex. Structure, 20, 2012
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3HWP
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![BU of 3hwp by Molmil](/molmil-images/mine/3hwp) | Crystal structure and computational analyses provide insights into the catalytic mechanism of 2, 4-diacetylphloroglucinol hydrolase PhlG from Pseudomonas fluorescens | Descriptor: | CHLORIDE ION, NICKEL (II) ION, PhlG, ... | Authors: | He, Y.-X, Huang, L, Xue, Y, Fei, X, Teng, Y.-B, Zhou, C.-Z. | Deposit date: | 2009-06-18 | Release date: | 2009-12-15 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure and Computational Analyses Provide Insights into the Catalytic Mechanism of 2,4-Diacetylphloroglucinol Hydrolase PhlG from Pseudomonas fluorescens. J.Biol.Chem., 285, 2010
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2JTM
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![BU of 2jtm by Molmil](/molmil-images/mine/2jtm) | Solution structure of Sso6901 from Sulfolobus solfataricus P2 | Descriptor: | Putative uncharacterized protein | Authors: | Feng, Y, Guo, L, Huang, L, Wang, J. | Deposit date: | 2007-08-03 | Release date: | 2008-04-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Biochemical and structural characterization of Cren7, a novel chromatin protein conserved among Crenarchaea Nucleic Acids Res., 36, 2008
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4MM0
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![BU of 4mm0 by Molmil](/molmil-images/mine/4mm0) | Crystal Structure Analysis of the Putative Thioether Synthase SgvP Involved in the Tailoring Step of Griseoviridin | Descriptor: | P450-like monooxygenase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Zhang, H, Huang, L, Yi, M, Cai, T, Zhang, H. | Deposit date: | 2013-09-07 | Release date: | 2014-09-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Analysis of SgvP: a Putative Thioether Synthase Involved in the Tailoring Step of Griseoviridin To be Published
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6K8N
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![BU of 6k8n by Molmil](/molmil-images/mine/6k8n) | Crystal structure of the Sulfolobus solfataricus topoisomerase III | Descriptor: | ZINC ION, topoisomerase III | Authors: | Wang, H.Q, Zhang, J.H, Zheng, X, Zheng, Z.F, Dong, Y.H, Huang, L, Gong, Y. | Deposit date: | 2019-06-13 | Release date: | 2020-06-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of the Sulfolobus solfataricus topoisomerase III reveal that its C-terminal novel zinc finger part is a unique decatenation domain To Be Published
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2ZB4
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![BU of 2zb4 by Molmil](/molmil-images/mine/2zb4) | Crystal structure of human 15-ketoprostaglandin delta-13-reductase in complex with NADP and 15-keto-PGE2 | Descriptor: | (5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Prostaglandin reductase 2, ... | Authors: | Wu, Y.H, Wang, A.H.J, Ko, T.P, Guo, R.T, Hu, S.M, Chuang, L.M. | Deposit date: | 2007-10-16 | Release date: | 2008-09-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Structural basis for catalytic and inhibitory mechanisms of human prostaglandin reductase PTGR2. Structure, 16, 2008
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2ZB8
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![BU of 2zb8 by Molmil](/molmil-images/mine/2zb8) | Crystal structure of human 15-ketoprostaglandin delta-13-reductase in complex with NADP and indomethacin | Descriptor: | INDOMETHACIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Prostaglandin reductase 2, ... | Authors: | Wu, Y.H, Wang, A.H.J, Ko, T.P, Guo, R.T, Hu, S.M, Chuang, L.M. | Deposit date: | 2007-10-16 | Release date: | 2008-09-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for catalytic and inhibitory mechanisms of human prostaglandin reductase PTGR2. Structure, 16, 2008
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2ZB3
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![BU of 2zb3 by Molmil](/molmil-images/mine/2zb3) | Crystal structure of mouse 15-ketoprostaglandin delta-13-reductase in complex with NADPH | Descriptor: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Prostaglandin reductase 2 | Authors: | Wu, Y.H, Wang, A.H.J, Ko, T.P, Guo, R.T, Hu, S.M, Chuang, L.M. | Deposit date: | 2007-10-16 | Release date: | 2008-09-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for catalytic and inhibitory mechanisms of human prostaglandin reductase PTGR2. Structure, 16, 2008
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2ZB7
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![BU of 2zb7 by Molmil](/molmil-images/mine/2zb7) | Crystal structure of human 15-ketoprostaglandin delta-13-reductase in complex with NADPH and nicotinamide | Descriptor: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NICOTINAMIDE, Prostaglandin reductase 2 | Authors: | Wu, Y.H, Wang, A.H.J, Ko, T.P, Guo, R.T, Hu, S.M, Chuang, L.M. | Deposit date: | 2007-10-16 | Release date: | 2008-09-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for catalytic and inhibitory mechanisms of human prostaglandin reductase PTGR2. Structure, 16, 2008
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4DKS
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![BU of 4dks by Molmil](/molmil-images/mine/4dks) | A spindle-shaped virus protein (chymotrypsin treated) | Descriptor: | Probable integrase | Authors: | Ouyang, S, Liang, W, Huang, L, Liu, Z.-J. | Deposit date: | 2012-02-04 | Release date: | 2012-05-30 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and functional characterization of the C-terminal catalytic domain of SSV1 integrase. Acta Crystallogr.,Sect.D, 68, 2012
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4E2P
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![BU of 4e2p by Molmil](/molmil-images/mine/4e2p) | Crystal Structure of a Post-tailoring Hydroxylase (HmtN) Involved in the Himastatin Biosynthesis | Descriptor: | Cytochrome P450 107B1 (P450CVIIB1), MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Zhang, H.D, Chen, J, Wang, H, Huang, L, Zhang, H.J. | Deposit date: | 2012-03-09 | Release date: | 2013-03-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Crystal Structure of a Post-tailoring Hydroxylase (HmtN) Involved in the Himastatin Biosynthesis To be Published
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4EFA
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![BU of 4efa by Molmil](/molmil-images/mine/4efa) | Crystal Structure of the Heterotrimeric EGChead Peripheral Stalk Complex of the Yeast Vacuolar ATPase - second conformation | Descriptor: | SULFATE ION, V-type proton ATPase subunit C, V-type proton ATPase subunit E, ... | Authors: | Oot, R.A, Huang, L.S, Berry, E.A, Wilkens, S. | Deposit date: | 2012-03-29 | Release date: | 2012-10-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.8163 Å) | Cite: | Crystal Structure of the Yeast Vacuolar ATPase Heterotrimeric EGC(head) Peripheral Stalk Complex. Structure, 20, 2012
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6K8O
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![BU of 6k8o by Molmil](/molmil-images/mine/6k8o) | Crystal structure of the Sulfolobus solfataricus topoisomerase III in complex with DNA | Descriptor: | DNA (5'-D(*GP*CP*AP*AP*GP*GP*TP*C)-3'), ZINC ION, topoisomerase III | Authors: | Wang, H.Q, Zhang, J.H, Zheng, X, Zheng, Z.F, Dong, Y.H, Huang, L, Gong, Y. | Deposit date: | 2019-06-13 | Release date: | 2020-06-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of the Sulfolobus solfataricus topoisomerase III reveal that its C-terminal novel zinc finger part is a unique decatenation domain To Be Published
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7XI6
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![BU of 7xi6 by Molmil](/molmil-images/mine/7xi6) | Crystal structure of C56 from pSSVi | Descriptor: | C56 | Authors: | Zhang, Z.F, Ren, Y, Chen, Y.Y, Zhang, X.W, Dong, Y.H, Gong, Y, Cao, P, Huang, L. | Deposit date: | 2022-04-12 | Release date: | 2023-04-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Characterization of the AbrB-like protein C56 conserved in a novel family of integrated genetic elements in Sulfolobales To Be Published
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3VCF
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![BU of 3vcf by Molmil](/molmil-images/mine/3vcf) | SSV1 integrase C-terminal catalytic domain (174-335aa) | Descriptor: | Probable integrase | Authors: | Ouyang, S, Liang, W, Huang, L, Liu, Z.-J. | Deposit date: | 2012-01-04 | Release date: | 2012-05-30 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and functional characterization of the C-terminal catalytic domain of SSV1 integrase. Acta Crystallogr.,Sect.D, 68, 2012
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7VT0
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![BU of 7vt0 by Molmil](/molmil-images/mine/7vt0) | Dimer structure of SORLA | Descriptor: | Sortilin-related receptor | Authors: | Xi, Z, Cang, W, Chuang, L. | Deposit date: | 2021-10-27 | Release date: | 2022-11-02 | Last modified: | 2023-05-17 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures reveal distinct apo conformations of sortilin-related receptor SORLA. Biochem.Biophys.Res.Commun., 600, 2022
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6N48
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![BU of 6n48 by Molmil](/molmil-images/mine/6n48) | Structure of beta2 adrenergic receptor bound to BI167107, Nanobody 6B9, and a positive allosteric modulator | Descriptor: | (2S)-2,3-dihydroxypropyl (7Z)-tetradec-7-enoate, 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, Camelid Antibody Fragment, ... | Authors: | Liu, X, Masoudi, A, Kahsai, A.W, Huang, L.Y, Pani, B, Hirata, K, Ahn, S, Lefkowitz, R.J, Kobilka, B.K. | Deposit date: | 2018-11-17 | Release date: | 2019-06-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Mechanism of beta2AR regulation by an intracellular positive allosteric modulator. Science, 364, 2019
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2KKE
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![BU of 2kke by Molmil](/molmil-images/mine/2kke) | Solution NMR Structure of a dimeric protein of unknown function from Methanobacterium thermoautotrophicum, Northeast Structural Genomics Consortium Target TR5 | Descriptor: | Uncharacterized protein | Authors: | Swapna, G.V.T, Gunsalus, X, Huang, L, Xiao, K, Everett, J.K, Acton, T.B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-06-18 | Release date: | 2009-07-14 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | NMR Solution Structure of a putative uncharacterized protein from Methanobacterium thermoautotrophicum, Northeast Structural Genomics Consortium Target:TR5 To be Published
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