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PDB: 156 件
5FBH
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Crystal structure of the extracellular domain of human calcium sensing receptor with bound Gd3+
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, CHLORIDE ION, ...
著者Zhang, T, Zhang, C, Miller, C.L, Zou, J, Moremen, K.W, Brown, E.M, Yang, J.J, Hu, J.
登録日2015-12-14
公開日2016-06-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist.
Sci Adv, 2, 2016
4DAJ
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Structure of the M3 Muscarinic Acetylcholine Receptor
分子名称: (1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane, Muscarinic acetylcholine receptor M3, Lysozyme, ...
著者Kruse, A.C, Hu, J, Pan, A.C, Arlow, D.H, Rosenbaum, D.M, Rosemond, E, Green, H.F, Liu, T, Chae, P.S, Dror, R.O, Shaw, D.E, Weis, W.I, Wess, J, Kobilka, B.
登録日2012-01-12
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structure and dynamics of the M3 muscarinic acetylcholine receptor.
Nature, 482, 2012
5FBK
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BU of 5fbk by Molmil
Crystal structure of the extracellular domain of human calcium sensing receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, CHLORIDE ION, ...
著者Zhang, T, Zhang, C, Miller, C.L, Zou, J, Moremen, K.W, Brown, E.M, Yang, J.J, Hu, J.
登録日2015-12-14
公開日2016-06-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist.
Sci Adv, 2, 2016
4X82
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BU of 4x82 by Molmil
Crystal Structure of the Extracellular Domain of ZIP4
分子名称: Zinc transporter ZIP4
著者Zhang, T, Sui, D.X, Hu, J.
登録日2014-12-09
公開日2016-06-15
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Structural insights of ZIP4 extracellular domain critical for optimal zinc transport.
Nat Commun, 7, 2016
4L1M
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BU of 4l1m by Molmil
Structure of the first RCC1-like domain of HERC2
分子名称: E3 ubiquitin-protein ligase HERC2, SULFATE ION, UNKNOWN ATOM OR ION
著者Tempel, W, Khan, M.B, Dong, A, Hu, J, Li, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC)
登録日2013-06-03
公開日2013-07-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of the first RCC1-like domain of HERC2
TO BE PUBLISHED
4JUY
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BU of 4juy by Molmil
Crystal structure of the PUB domain of E3 ubiquitin ligase RNF31
分子名称: E3 ubiquitin-protein ligase RNF31, UNKNOWN ATOM OR ION
著者Dong, A, Hu, J, Li, Y, Wernimont, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC)
登録日2013-03-25
公開日2013-04-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the PUB domain of E3 ubiquitin ligase RNF31
To be Published
4KFV
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BU of 4kfv by Molmil
Structural insight into Golgi membrane stacking by GRASP65 and GRASP55
分子名称: CHLORIDE ION, Golgi reassembly-stacking protein 1, ZINC ION
著者Liu, X, Hu, J.
登録日2013-04-28
公開日2013-08-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural insight into Golgi membrane stacking by GRASP65 and GRASP55 proteins
J.Biol.Chem., 288, 2013
3PMR
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BU of 3pmr by Molmil
Crystal Structure of E2 domain of Human Amyloid Precursor-Like Protein 1
分子名称: Amyloid-like protein 1, PHOSPHATE ION
著者Lee, S, Xue, Y, Hu, J, Wang, Y, Liu, X, Demeler, B, Ha, Y.
登録日2010-11-17
公開日2011-06-01
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献The E2 Domains of APP and APLP1 Share a Conserved Mode of Dimerization.
Biochemistry, 50, 2011
4KFW
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Structural insight into Golgi membrane stacking by GRASP65 and GRASP55
分子名称: Golgi reassembly stacking protein 2
著者Liu, X, Hu, J.
登録日2013-04-28
公開日2013-08-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural insight into Golgi membrane stacking by GRASP65 and GRASP55 proteins
J.Biol.Chem., 288, 2013
6CBA
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BU of 6cba by Molmil
Ethylene forming enzyme in complex with manganese, 2-oxoglutarate and canavanine
分子名称: 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, L-CANAVANINE, ...
著者Fellner, M, Martinez, S, Hu, J, Hausinger, R.P.
登録日2018-02-02
公開日2019-02-06
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (1.13 Å)
主引用文献Structural, Spectroscopic, and Computational Insights from Canavanine-Bound and Two Catalytically Compromised Variants of the Ethylene-Forming Enzyme.
Biochemistry, 2024
7MJ1
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BU of 7mj1 by Molmil
LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with NAD
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Chatterjee, S, Rankin, J.A, Lagishetty, S, Hu, J, Hausinger, R.P.
登録日2021-04-19
公開日2021-09-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.402 Å)
主引用文献The LarB carboxylase/hydrolase forms a transient cysteinyl-pyridine intermediate during nickel-pincer nucleotide cofactor biosynthesis.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MJ0
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BU of 7mj0 by Molmil
LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with adenosine monophosphate AMP
分子名称: ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, Pyridinium-3,5-biscarboxylic acid mononucleotide synthase
著者Chatterjee, S, Rankin, J.A, Lagishetty, S, Hu, J, Hausinger, R.P.
登録日2021-04-19
公開日2021-09-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献The LarB carboxylase/hydrolase forms a transient cysteinyl-pyridine intermediate during nickel-pincer nucleotide cofactor biosynthesis.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MJ2
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BU of 7mj2 by Molmil
LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with Zn
分子名称: MAGNESIUM ION, Pyridinium-3,5-biscarboxylic acid mononucleotide synthase, ZINC ION
著者Chatterjee, S, Rankin, J.A, Lagishetty, S, Hu, J, Hausinger, R.P.
登録日2021-04-19
公開日2021-09-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The LarB carboxylase/hydrolase forms a transient cysteinyl-pyridine intermediate during nickel-pincer nucleotide cofactor biosynthesis.
Proc.Natl.Acad.Sci.USA, 118, 2021
6CN3
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BU of 6cn3 by Molmil
Crystal structure of zebrafish Phosphatidylinositol-4-phosphate 5- kinase alpha isoform D236A
分子名称: Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
著者Zeng, X, Sui, D, Hu, J.
登録日2018-03-07
公開日2018-03-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.351 Å)
主引用文献Structural insights into lethal contractural syndrome type 3 (LCCS3) caused by a missense mutation of PIP5K gamma.
Biochem. J., 475, 2018
5GNR
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BU of 5gnr by Molmil
the structure of mini-MFN1 K88A in complex with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, Mitofusin-1
著者Yan, L, Yu, C, Ming, Z, Lou, Z, Rao, Z, Hu, J.
登録日2016-07-24
公開日2016-11-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献BDLP-like folding of Mitofusin 1
To Be Published
6CN2
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BU of 6cn2 by Molmil
Crystal structure of zebrafish Phosphatidylinositol-4-phosphate 5- kinase alpha isoform D236N with bound ATP/Ca2+
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Phosphatidylinositol-4-phosphate 5-kinase, ...
著者Zeng, X, Sui, D, Hu, J.
登録日2018-03-07
公開日2018-03-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.102 Å)
主引用文献Structural insights into lethal contractural syndrome type 3 (LCCS3) caused by a missense mutation of PIP5K gamma.
Biochem. J., 475, 2018
6CF3
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BU of 6cf3 by Molmil
Ethylene forming enzyme Y306A variant in complex with manganese and 2-oxoglutarate
分子名称: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, ...
著者Fellner, M, Martinez, S, Hu, J, Hausinger, R.P.
登録日2018-02-13
公開日2019-02-13
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Structural, Spectroscopic, and Computational Insights from Canavanine-Bound and Two Catalytically Compromised Variants of the Ethylene-Forming Enzyme.
Biochemistry, 2024
6BWQ
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BU of 6bwq by Molmil
LarC2, the C-terminal domain of a cyclometallase involved in the synthesis of the NPN cofactor of lactate racemase, in complex with MnCTP
分子名称: CHLORIDE ION, CYTIDINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
著者Fellner, M, Hausinger, R.P, Hu, J.
登録日2017-12-15
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase.
J. Biol. Chem., 293, 2018
6BWO
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BU of 6bwo by Molmil
LarC2, the C-terminal domain of a cyclometallase involved in the synthesis of the NPN cofactor of lactate racemase, apo form
分子名称: Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein
著者Fellner, M, Desguin, B, Hausinger, R.P, Hu, J.
登録日2017-12-15
公開日2018-06-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase.
J. Biol. Chem., 293, 2018
2K3K
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BU of 2k3k by Molmil
Solution structure of Drosophila melanogaster SNF RBD1
分子名称: U1 small nuclear ribonucleoprotein A
著者Liu, C, Cui, G, Hu, J, Jin, C, Xia, B.
登録日2008-05-12
公開日2008-06-03
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural and Functional Studies of RNA Splicing Factor Sans-Fille by Multidimentional NMR Spectroscopy
To be Published
4FO9
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BU of 4fo9 by Molmil
Crystal structure of the E3 SUMO Ligase PIAS2
分子名称: E3 SUMO-protein ligase PIAS2, UNKNOWN ATOM OR ION, ZINC ION
著者Dong, A, Hu, J, Dobrovetsky, E, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC)
登録日2012-06-20
公開日2012-07-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Crystal structure of the E3 SUMO Ligase PIAS2
to be published
5HUQ
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BU of 5huq by Molmil
A tethered niacin-derived pincer complex with a nickel-carbon bond in lactate racemase
分子名称: 3-methanethioyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium, Lactate racemization operon protein LarA, NICKEL (II) ION, ...
著者Desguin, B, Zhang, T, Soumillion, P, Hols, P, Hu, J, Hausinger, R.P.
登録日2016-01-27
公開日2016-02-10
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献METALLOPROTEINS. A tethered niacin-derived pincer complex with a nickel-carbon bond in lactate racemase.
Science, 349, 2015
6BWR
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BU of 6bwr by Molmil
LarC2, the C-terminal domain of a cyclometallase involved in the synthesis of the NPN cofactor of lactate racemase, in complex with nickel
分子名称: NICKEL (II) ION, Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein
著者Fellner, M, Hausinger, R.P, Hu, J.
登録日2017-12-15
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase.
J. Biol. Chem., 293, 2018
6D6Z
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BU of 6d6z by Molmil
Structure of the malate racemase apoprotein from Thermoanaerobacterium thermosaccharolyticum
分子名称: Malate racemase Mar2
著者Fellner, M, Hausinger, R.P, Hu, J.
登録日2018-04-23
公開日2019-04-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Uncovering a superfamily of nickel-dependent hydroxyacid racemases and epimerases.
Sci Rep, 10, 2020
6CMW
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BU of 6cmw by Molmil
Crystal structure of zebrafish Phosphatidylinositol-4-phosphate 5- kinase alpha isoform with bound ATP/Ca2+
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Phosphatidylinositol-4-phosphate 5-kinase, ...
著者Zeng, X, Sui, D, Hu, J.
登録日2018-03-06
公開日2018-03-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structural insights into lethal contractural syndrome type 3 (LCCS3) caused by a missense mutation of PIP5K gamma.
Biochem. J., 475, 2018

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