5FBH
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![BU of 5fbh by Molmil](/molmil-images/mine/5fbh) | Crystal structure of the extracellular domain of human calcium sensing receptor with bound Gd3+ | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, CHLORIDE ION, ... | 著者 | Zhang, T, Zhang, C, Miller, C.L, Zou, J, Moremen, K.W, Brown, E.M, Yang, J.J, Hu, J. | 登録日 | 2015-12-14 | 公開日 | 2016-06-22 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist. Sci Adv, 2, 2016
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4DAJ
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![BU of 4daj by Molmil](/molmil-images/mine/4daj) | Structure of the M3 Muscarinic Acetylcholine Receptor | 分子名称: | (1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane, Muscarinic acetylcholine receptor M3, Lysozyme, ... | 著者 | Kruse, A.C, Hu, J, Pan, A.C, Arlow, D.H, Rosenbaum, D.M, Rosemond, E, Green, H.F, Liu, T, Chae, P.S, Dror, R.O, Shaw, D.E, Weis, W.I, Wess, J, Kobilka, B. | 登録日 | 2012-01-12 | 公開日 | 2012-02-22 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structure and dynamics of the M3 muscarinic acetylcholine receptor. Nature, 482, 2012
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5FBK
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![BU of 5fbk by Molmil](/molmil-images/mine/5fbk) | Crystal structure of the extracellular domain of human calcium sensing receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, CHLORIDE ION, ... | 著者 | Zhang, T, Zhang, C, Miller, C.L, Zou, J, Moremen, K.W, Brown, E.M, Yang, J.J, Hu, J. | 登録日 | 2015-12-14 | 公開日 | 2016-06-22 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist. Sci Adv, 2, 2016
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4X82
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4L1M
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![BU of 4l1m by Molmil](/molmil-images/mine/4l1m) | Structure of the first RCC1-like domain of HERC2 | 分子名称: | E3 ubiquitin-protein ligase HERC2, SULFATE ION, UNKNOWN ATOM OR ION | 著者 | Tempel, W, Khan, M.B, Dong, A, Hu, J, Li, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | 登録日 | 2013-06-03 | 公開日 | 2013-07-03 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of the first RCC1-like domain of HERC2 TO BE PUBLISHED
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4JUY
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![BU of 4juy by Molmil](/molmil-images/mine/4juy) | Crystal structure of the PUB domain of E3 ubiquitin ligase RNF31 | 分子名称: | E3 ubiquitin-protein ligase RNF31, UNKNOWN ATOM OR ION | 著者 | Dong, A, Hu, J, Li, Y, Wernimont, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | 登録日 | 2013-03-25 | 公開日 | 2013-04-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of the PUB domain of E3 ubiquitin ligase RNF31 To be Published
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4KFV
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3PMR
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![BU of 3pmr by Molmil](/molmil-images/mine/3pmr) | Crystal Structure of E2 domain of Human Amyloid Precursor-Like Protein 1 | 分子名称: | Amyloid-like protein 1, PHOSPHATE ION | 著者 | Lee, S, Xue, Y, Hu, J, Wang, Y, Liu, X, Demeler, B, Ha, Y. | 登録日 | 2010-11-17 | 公開日 | 2011-06-01 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | The E2 Domains of APP and APLP1 Share a Conserved Mode of Dimerization. Biochemistry, 50, 2011
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4KFW
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6CBA
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![BU of 6cba by Molmil](/molmil-images/mine/6cba) | Ethylene forming enzyme in complex with manganese, 2-oxoglutarate and canavanine | 分子名称: | 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, L-CANAVANINE, ... | 著者 | Fellner, M, Martinez, S, Hu, J, Hausinger, R.P. | 登録日 | 2018-02-02 | 公開日 | 2019-02-06 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | 主引用文献 | Structural, Spectroscopic, and Computational Insights from Canavanine-Bound and Two Catalytically Compromised Variants of the Ethylene-Forming Enzyme. Biochemistry, 2024
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7MJ1
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![BU of 7mj1 by Molmil](/molmil-images/mine/7mj1) | LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with NAD | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Chatterjee, S, Rankin, J.A, Lagishetty, S, Hu, J, Hausinger, R.P. | 登録日 | 2021-04-19 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.402 Å) | 主引用文献 | The LarB carboxylase/hydrolase forms a transient cysteinyl-pyridine intermediate during nickel-pincer nucleotide cofactor biosynthesis. Proc.Natl.Acad.Sci.USA, 118, 2021
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7MJ0
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![BU of 7mj0 by Molmil](/molmil-images/mine/7mj0) | LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with adenosine monophosphate AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, Pyridinium-3,5-biscarboxylic acid mononucleotide synthase | 著者 | Chatterjee, S, Rankin, J.A, Lagishetty, S, Hu, J, Hausinger, R.P. | 登録日 | 2021-04-19 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | The LarB carboxylase/hydrolase forms a transient cysteinyl-pyridine intermediate during nickel-pincer nucleotide cofactor biosynthesis. Proc.Natl.Acad.Sci.USA, 118, 2021
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7MJ2
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![BU of 7mj2 by Molmil](/molmil-images/mine/7mj2) | LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with Zn | 分子名称: | MAGNESIUM ION, Pyridinium-3,5-biscarboxylic acid mononucleotide synthase, ZINC ION | 著者 | Chatterjee, S, Rankin, J.A, Lagishetty, S, Hu, J, Hausinger, R.P. | 登録日 | 2021-04-19 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The LarB carboxylase/hydrolase forms a transient cysteinyl-pyridine intermediate during nickel-pincer nucleotide cofactor biosynthesis. Proc.Natl.Acad.Sci.USA, 118, 2021
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6CN3
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5GNR
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![BU of 5gnr by Molmil](/molmil-images/mine/5gnr) | the structure of mini-MFN1 K88A in complex with GDP | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Mitofusin-1 | 著者 | Yan, L, Yu, C, Ming, Z, Lou, Z, Rao, Z, Hu, J. | 登録日 | 2016-07-24 | 公開日 | 2016-11-23 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | BDLP-like folding of Mitofusin 1 To Be Published
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6CN2
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![BU of 6cn2 by Molmil](/molmil-images/mine/6cn2) | Crystal structure of zebrafish Phosphatidylinositol-4-phosphate 5- kinase alpha isoform D236N with bound ATP/Ca2+ | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Phosphatidylinositol-4-phosphate 5-kinase, ... | 著者 | Zeng, X, Sui, D, Hu, J. | 登録日 | 2018-03-07 | 公開日 | 2018-03-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.102 Å) | 主引用文献 | Structural insights into lethal contractural syndrome type 3 (LCCS3) caused by a missense mutation of PIP5K gamma. Biochem. J., 475, 2018
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6CF3
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![BU of 6cf3 by Molmil](/molmil-images/mine/6cf3) | Ethylene forming enzyme Y306A variant in complex with manganese and 2-oxoglutarate | 分子名称: | 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, ... | 著者 | Fellner, M, Martinez, S, Hu, J, Hausinger, R.P. | 登録日 | 2018-02-13 | 公開日 | 2019-02-13 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | Structural, Spectroscopic, and Computational Insights from Canavanine-Bound and Two Catalytically Compromised Variants of the Ethylene-Forming Enzyme. Biochemistry, 2024
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6BWQ
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![BU of 6bwq by Molmil](/molmil-images/mine/6bwq) | LarC2, the C-terminal domain of a cyclometallase involved in the synthesis of the NPN cofactor of lactate racemase, in complex with MnCTP | 分子名称: | CHLORIDE ION, CYTIDINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... | 著者 | Fellner, M, Hausinger, R.P, Hu, J. | 登録日 | 2017-12-15 | 公開日 | 2018-06-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase. J. Biol. Chem., 293, 2018
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6BWO
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![BU of 6bwo by Molmil](/molmil-images/mine/6bwo) | LarC2, the C-terminal domain of a cyclometallase involved in the synthesis of the NPN cofactor of lactate racemase, apo form | 分子名称: | Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein | 著者 | Fellner, M, Desguin, B, Hausinger, R.P, Hu, J. | 登録日 | 2017-12-15 | 公開日 | 2018-06-20 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase. J. Biol. Chem., 293, 2018
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2K3K
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4FO9
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![BU of 4fo9 by Molmil](/molmil-images/mine/4fo9) | Crystal structure of the E3 SUMO Ligase PIAS2 | 分子名称: | E3 SUMO-protein ligase PIAS2, UNKNOWN ATOM OR ION, ZINC ION | 著者 | Dong, A, Hu, J, Dobrovetsky, E, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | 登録日 | 2012-06-20 | 公開日 | 2012-07-18 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Crystal structure of the E3 SUMO Ligase PIAS2 to be published
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5HUQ
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![BU of 5huq by Molmil](/molmil-images/mine/5huq) | A tethered niacin-derived pincer complex with a nickel-carbon bond in lactate racemase | 分子名称: | 3-methanethioyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium, Lactate racemization operon protein LarA, NICKEL (II) ION, ... | 著者 | Desguin, B, Zhang, T, Soumillion, P, Hols, P, Hu, J, Hausinger, R.P. | 登録日 | 2016-01-27 | 公開日 | 2016-02-10 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | METALLOPROTEINS. A tethered niacin-derived pincer complex with a nickel-carbon bond in lactate racemase. Science, 349, 2015
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6BWR
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![BU of 6bwr by Molmil](/molmil-images/mine/6bwr) | LarC2, the C-terminal domain of a cyclometallase involved in the synthesis of the NPN cofactor of lactate racemase, in complex with nickel | 分子名称: | NICKEL (II) ION, Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein | 著者 | Fellner, M, Hausinger, R.P, Hu, J. | 登録日 | 2017-12-15 | 公開日 | 2018-06-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase. J. Biol. Chem., 293, 2018
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6D6Z
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6CMW
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![BU of 6cmw by Molmil](/molmil-images/mine/6cmw) | Crystal structure of zebrafish Phosphatidylinositol-4-phosphate 5- kinase alpha isoform with bound ATP/Ca2+ | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Phosphatidylinositol-4-phosphate 5-kinase, ... | 著者 | Zeng, X, Sui, D, Hu, J. | 登録日 | 2018-03-06 | 公開日 | 2018-03-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Structural insights into lethal contractural syndrome type 3 (LCCS3) caused by a missense mutation of PIP5K gamma. Biochem. J., 475, 2018
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