6BWR
LarC2, the C-terminal domain of a cyclometallase involved in the synthesis of the NPN cofactor of lactate racemase, in complex with nickel
Summary for 6BWR
Entry DOI | 10.2210/pdb6bwr/pdb |
Descriptor | Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein, NICKEL (II) ION (3 entities in total) |
Functional Keywords | lar, nickel transferase, larc, hexamer, trimer, ctp, nickel, lactate, lactate racemization, lactate racemase, metal binding protein |
Biological source | Lactobacillus plantarum |
Total number of polymer chains | 2 |
Total formula weight | 33873.06 |
Authors | Fellner, M.,Hausinger, R.P.,Hu, J. (deposition date: 2017-12-15, release date: 2018-06-20, Last modification date: 2023-10-04) |
Primary citation | Desguin, B.,Fellner, M.,Riant, O.,Hu, J.,Hausinger, R.P.,Hols, P.,Soumillion, P. Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase. J. Biol. Chem., 293:12303-12317, 2018 Cited by PubMed: 29887527DOI: 10.1074/jbc.RA118.003741 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.81 Å) |
Structure validation
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