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PDB: 156 results

2HDX
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BU of 2hdx by Molmil
Crystal structure of the Src homology-2 domain of SH2-B in complex with Jak2 pTyr813 phosphopeptide
Descriptor: Jak2 protein, SH2-B PH domain containing signaling mediator 1 gamma isoform
Authors:Hu, J, Hubbard, S.R.
Deposit date:2006-06-21
Release date:2006-08-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS.
J.Mol.Biol., 361, 2006
6DWB
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BU of 6dwb by Molmil
Structure of the Salmonella SPI-1 type III secretion injectisome needle filament
Descriptor: Protein PrgI
Authors:Hu, J, Hong, C, Worrall, L.J, Vuckovic, M, Yu, Z, Strynadka, N.C.J.
Deposit date:2018-06-26
Release date:2018-10-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Nat Commun, 9, 2018
6DV3
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BU of 6dv3 by Molmil
Structure of the Salmonella SPI-1 type III secretion injectisome secretin InvG in the open gate state
Descriptor: Protein InvG
Authors:Hu, J, Worrall, L.J, Vuckovic, M, Atkinson, C.E, Strynadka, N.C.J.
Deposit date:2018-06-22
Release date:2018-10-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Nat Commun, 9, 2018
6DUZ
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BU of 6duz by Molmil
Structure of the periplasmic domains of PrgH and PrgK from the assembled Salmonella type III secretion injectisome needle complex
Descriptor: Lipoprotein PrgK, Protein PrgH
Authors:Hu, J, Worrall, L.J, Vuckovic, M, Atkinson, C.E, Strynadka, N.C.J.
Deposit date:2018-06-22
Release date:2018-10-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Nat Commun, 9, 2018
6DV6
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BU of 6dv6 by Molmil
Structure of the Salmonella SPI-1 type III secretion injectisome secretin InvG (residues 176-end) in the open gate state
Descriptor: Protein InvG
Authors:Hu, J, Worrall, L.J, Vuckovic, M, Atkinson, C.E, Strynadka, N.C.J.
Deposit date:2018-06-22
Release date:2018-10-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Nat Commun, 9, 2018
3S0X
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BU of 3s0x by Molmil
The crystal structure of GxGD membrane protease FlaK
Descriptor: Peptidase A24B, FlaK domain protein
Authors:Hu, J, Xue, Y, Ha, Y.
Deposit date:2011-05-13
Release date:2011-08-03
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The crystal structure of GXGD membrane protease FlaK.
Nature, 475, 2011
5YDU
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BU of 5ydu by Molmil
Crystal structure of Utp30
Descriptor: PHOSPHATE ION, Ribosome biogenesis protein UTP30
Authors:Hu, J, Zhu, X, Ye, K.
Deposit date:2017-09-14
Release date:2017-11-01
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.646 Å)
Cite:Structure and RNA recognition of ribosome assembly factor Utp30.
RNA, 23, 2017
5TEQ
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BU of 5teq by Molmil
C20S C293G MUTANT N-TERMINAL HUMAN ATP CITRATE LYASE BOUND TO CITRATE
Descriptor: ATP-citrate synthase, CITRATE ANION, PHOSPHATE ION, ...
Authors:Hu, J, Fraser, M.E.
Deposit date:2016-09-22
Release date:2017-08-09
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TDZ
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BU of 5tdz by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to Tartrate and ADP
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Hu, J, Fraser, M.E.
Deposit date:2016-09-20
Release date:2017-08-09
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TES
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BU of 5tes by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to Citrate and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, CITRATE ANION, ...
Authors:Hu, J, Fraser, M.E.
Deposit date:2016-09-22
Release date:2017-08-09
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TDF
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BU of 5tdf by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to 4S hydroxycitrate
Descriptor: 3-C-carboxy-2-deoxy-D-erythro-pentaric acid, ADENINE, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Hu, J, Fraser, M.E.
Deposit date:2016-09-19
Release date:2017-08-09
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TET
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BU of 5tet by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to 4S Hydroxycitrate
Descriptor: 3-C-carboxy-2-deoxy-D-erythro-pentaric acid, ATP-citrate synthase, GLYCEROL, ...
Authors:Hu, J, Fraser, M.E.
Deposit date:2016-09-22
Release date:2017-08-09
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TDM
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BU of 5tdm by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to 4R-Hydroxycitrate and ADP
Descriptor: 3-C-carboxy-2-deoxy-L-threo-pentaric acid, ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Hu, J, Fraser, M.E.
Deposit date:2016-09-19
Release date:2017-08-09
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TE1
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BU of 5te1 by Molmil
C20S, C293G Mutant N-terminal Human ATP Citrate Lyase Bound to 4R-Hydroxycitrate
Descriptor: 3-C-carboxy-2-deoxy-L-threo-pentaric acid, ATP-citrate synthase, PHOSPHATE ION, ...
Authors:Hu, J, Fraser, M.E.
Deposit date:2016-09-20
Release date:2017-08-09
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TDE
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BU of 5tde by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to Citrate
Descriptor: ATP-citrate synthase, CITRATE ANION, DIHYDROGENPHOSPHATE ION, ...
Authors:Hu, J, Fraser, M.E.
Deposit date:2016-09-19
Release date:2017-08-09
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
6PGI
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BU of 6pgi by Molmil
Asymmetric functions of a binuclear metal cluster within the transport pathway of the ZIP transition metal transporters
Descriptor: BbZIP, CADMIUM ION
Authors:Zhang, T, Sui, D, Zhang, C, Logan, T, Hu, J.
Deposit date:2019-06-24
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Asymmetric functions of a binuclear metal center within the transport pathway of a human zinc transporter ZIP4.
Faseb J., 34, 2020
6CBA
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BU of 6cba by Molmil
Ethylene forming enzyme in complex with manganese, 2-oxoglutarate and canavanine
Descriptor: 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, L-CANAVANINE, ...
Authors:Fellner, M, Martinez, S, Hu, J, Hausinger, R.P.
Deposit date:2018-02-02
Release date:2019-02-06
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:Structural, Spectroscopic, and Computational Insights from Canavanine-Bound and Two Catalytically Compromised Variants of the Ethylene-Forming Enzyme.
Biochemistry, 2024
6CN2
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BU of 6cn2 by Molmil
Crystal structure of zebrafish Phosphatidylinositol-4-phosphate 5- kinase alpha isoform D236N with bound ATP/Ca2+
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Phosphatidylinositol-4-phosphate 5-kinase, ...
Authors:Zeng, X, Sui, D, Hu, J.
Deposit date:2018-03-07
Release date:2018-03-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.102 Å)
Cite:Structural insights into lethal contractural syndrome type 3 (LCCS3) caused by a missense mutation of PIP5K gamma.
Biochem. J., 475, 2018
6CMW
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BU of 6cmw by Molmil
Crystal structure of zebrafish Phosphatidylinositol-4-phosphate 5- kinase alpha isoform with bound ATP/Ca2+
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Phosphatidylinositol-4-phosphate 5-kinase, ...
Authors:Zeng, X, Sui, D, Hu, J.
Deposit date:2018-03-06
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural insights into lethal contractural syndrome type 3 (LCCS3) caused by a missense mutation of PIP5K gamma.
Biochem. J., 475, 2018
5V2X
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BU of 5v2x by Molmil
Ethylene forming enzyme in complex with manganese and 2-oxoglutarate
Descriptor: 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, MANGANESE (II) ION
Authors:Fellner, M, Martinez, S, Hu, J, Hausinger, R.P.
Deposit date:2017-03-06
Release date:2017-08-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.847 Å)
Cite:Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist.
J. Am. Chem. Soc., 139, 2017
5V2V
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BU of 5v2v by Molmil
Ethylene forming enzyme in complex with nickel
Descriptor: 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, NICKEL (II) ION
Authors:Fellner, M, Martinez, S, Hu, J, Hausinger, R.P.
Deposit date:2017-03-06
Release date:2017-08-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist.
J. Am. Chem. Soc., 139, 2017
5V2Y
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BU of 5v2y by Molmil
Ethylene forming enzyme in complex with manganese, 2-oxoglutarate and L-arginine
Descriptor: 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, ARGININE, ...
Authors:Fellner, M, Martinez, S, Hu, J, Hausinger, R.P.
Deposit date:2017-03-06
Release date:2017-08-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.428 Å)
Cite:Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist.
J. Am. Chem. Soc., 139, 2017
5V2U
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BU of 5v2u by Molmil
Ethylene forming enzyme apo form
Descriptor: 2-oxoglutarate-dependent ethylene/succinate-forming enzyme
Authors:Fellner, M, Martinez, S, Hu, J, Hausinger, R.P.
Deposit date:2017-03-06
Release date:2017-08-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.058 Å)
Cite:Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist.
J. Am. Chem. Soc., 139, 2017
5V32
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BU of 5v32 by Molmil
Ethylene forming enzyme in complex with manganese and malic acid
Descriptor: 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, D-MALATE, MANGANESE (II) ION
Authors:Fellner, M, Martinez, S, Hu, J, Hausinger, R.P.
Deposit date:2017-03-06
Release date:2017-08-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.486 Å)
Cite:Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist.
J. Am. Chem. Soc., 139, 2017
5V34
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BU of 5v34 by Molmil
Ethylene forming enzyme in complex with manganese, malic acid and L-arginine
Descriptor: 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, ARGININE, D-MALATE, ...
Authors:Fellner, M, Martinez, S, Hu, J, Hausinger, R.P.
Deposit date:2017-03-06
Release date:2017-08-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist.
J. Am. Chem. Soc., 139, 2017

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