6UH5
 
 | | Structural basis of COMPASS eCM recognition of the H2Bub nucleosome | | 分子名称: | Bre2, DNA (146-MER), H3 N-terminus, ... | | 著者 | Hsu, P.L, Shi, H, Zheng, N. | | 登録日 | 2019-09-26 | | 公開日 | 2019-11-20 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS.
Mol.Cell, 76, 2019
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8T51
 | | Crystal structure of Fab 3.10C2 bound to TREM2 | | 分子名称: | 3.10C2 Fab heavy chain, 3.10C2 Fab light chain, ACETATE ION, ... | | 著者 | Hsu, P.L, Wallweber, H. | | 登録日 | 2023-06-12 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Rapid affinity optimization of an anti-TREM2 clinical lead antibody by cross-lineage immune repertoire mining.
Nat Commun, 15, 2024
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6CHG
 | | Crystal structure of the yeast COMPASS catalytic module | | 分子名称: | H3, Histone-lysine N-methyltransferase, H3 lysine-4 specific, ... | | 著者 | Hsu, P.L, Li, H, Zheng, N. | | 登録日 | 2018-02-22 | | 公開日 | 2018-08-22 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.985 Å) | | 主引用文献 | Crystal Structure of the COMPASS H3K4 Methyltransferase Catalytic Module.
Cell, 174, 2018
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6UGM
 | | Structural basis of COMPASS eCM recognition of an unmodified nucleosome | | 分子名称: | Bre2, DNA (146-MER), H3 N-terminus, ... | | 著者 | Hsu, P.L, Shi, H, Zheng, N. | | 登録日 | 2019-09-26 | | 公開日 | 2019-11-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS.
Mol.Cell, 76, 2019
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4M3O
 | | Crystal structure of K.lactis Rtr1 NTD | | 分子名称: | KLLA0F12672p, ZINC ION | | 著者 | Hsu, P.L, Yang, W, Zheng, N, Varani, G. | | 登録日 | 2013-08-06 | | 公開日 | 2014-07-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Rtr1 Is a Dual Specificity Phosphatase That Dephosphorylates Tyr1 and Ser5 on the RNA Polymerase II CTD.
J.Mol.Biol., 426, 2014
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8T59
 | | Crystal structure of Para.09 bound to TREM2 | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Para.09 heavy chain, ... | | 著者 | Wallweber, H, Hsu, P.L. | | 登録日 | 2023-06-12 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Rapid affinity optimization of an anti-TREM2 clinical lead antibody by cross-lineage immune repertoire mining.
Nat Commun, 15, 2024
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8VW5
 | | Crystal structure of Cbl-b TKB bound to compound 2 | | 分子名称: | CALCIUM ION, E3 ubiquitin-protein ligase CBL-B, MAGNESIUM ION, ... | | 著者 | Yu, C, Murray, J, Hsu, P.L. | | 登録日 | 2024-01-31 | | 公開日 | 2024-07-03 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Optimization of a Novel DEL Hit That Binds in the Cbl-b SH2 Domain and Blocks Substrate Binding.
Acs Med.Chem.Lett., 15, 2024
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8VW4
 | | Crystal structure of Cbl-b TKB bound to compound 26 | | 分子名称: | (7-methoxy-2-{2-[(1S,3S,4S)-3-(3-methoxy-2-methyl-5-nitrophenyl)-1-methyl-5-oxo-1,5-dihydroimidazo[1,5-a]pyridin-2(3H)-yl]-2-oxoethoxy}quinolin-8-yl)acetic acid, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase CBL-B, ... | | 著者 | Yu, C, Murray, J, Hsu, P.L. | | 登録日 | 2024-01-31 | | 公開日 | 2024-07-03 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Optimization of a Novel DEL Hit That Binds in the Cbl-b SH2 Domain and Blocks Substrate Binding.
Acs Med.Chem.Lett., 15, 2024
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