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PDB: 29 results
6NAW
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BU of 6naw by Molmil
Crystal structure of Neisseria meningitidis ClpP E58A activated mutant
Descriptor: ATP-dependent Clp protease proteolytic subunit
Authors:Mabanglo, M.F, Houry, W.A.
Deposit date:2018-12-06
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores.
Commun Biol, 2, 2019
6VFX
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BU of 6vfx by Molmil
ClpXP from Neisseria meningitidis - Conformation B
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ...
Authors:Ripstein, Z.A, Vahidi, S, Houry, W.A, Rubinstein, J.L, Kay, L.E.
Deposit date:2020-01-06
Release date:2020-01-22
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery.
Elife, 9, 2020
6VFS
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BU of 6vfs by Molmil
ClpXP from Neisseria meningitidis - Conformation A
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ...
Authors:Ripstein, Z.A, Vahidi, S, Houry, W.A, Rubinstein, J.L, Kay, L.E.
Deposit date:2020-01-06
Release date:2020-01-22
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery.
Elife, 9, 2020
6W9T
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BU of 6w9t by Molmil
Crystal structure of Neisseria meningitidis ClpP protease complex with small molecule activator ACP1-06
Descriptor: ATP-dependent Clp protease proteolytic subunit, N-{2-[(2-chlorophenyl)sulfanyl]ethyl}-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]sulfonyl}propanamide, POTASSIUM ION
Authors:Mabanglo, M.F, Houry, W.A.
Deposit date:2020-03-23
Release date:2020-12-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Development of Antibiotics That Dysregulate the Neisserial ClpP Protease.
Acs Infect Dis., 6, 2020
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