6S85
 
 | | Cutting state of the E. coli Mre11-Rad50 (SbcCD) head complex bound to ADP and dsDNA. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (31-MER), DNA (32-MER), ... | | 著者 | Kaeshammer, L, Saathoff, J.H, Gut, F, Bartho, J, Alt, A, Kessler, B, Lammens, K, Hopfner, K.P. | | 登録日 | 2019-07-08 | | 公開日 | 2019-09-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Mechanism of DNA End Sensing and Processing by the Mre11-Rad50 Complex.
Mol.Cell, 76, 2019
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6S6V
 | | Resting state of the E. coli Mre11-Rad50 (SbcCD) head complex bound to ATPgS | | 分子名称: | MAGNESIUM ION, MANGANESE (II) ION, Nuclease SbcCD subunit C, ... | | 著者 | Kaeshammer, L, Saathoff, J.H, Gut, F, Bartho, J, Alt, A, Kessler, B, Lammens, K, Hopfner, K.P. | | 登録日 | 2019-07-03 | | 公開日 | 2019-09-04 | | 最終更新日 | 2019-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Mechanism of DNA End Sensing and Processing by the Mre11-Rad50 Complex.
Mol.Cell, 76, 2019
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6SKY
 | | FAT and kinase domain of CtTel1 | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase Tel1 | | 著者 | Jansma, M, Eustermann, S.E, Kostrewa, D, Lammens, K, Hopfner, K.P. | | 登録日 | 2019-08-16 | | 公開日 | 2019-10-30 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State.
Structure, 28, 2020
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6SL0
 | | Complete CtTel1 dimer with C2 symmetry | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase Tel1 | | 著者 | Jansma, M, Eustermann, S.E, Kostrewa, D, Lammens, K, Hopfner, K.P. | | 登録日 | 2019-08-16 | | 公開日 | 2019-10-30 | | 最終更新日 | 2020-01-15 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State.
Structure, 28, 2020
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8ATF
 | | Nucleosome-bound Ino80 ATPase | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (226-MER), DNA (227-MER), ... | | 著者 | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | | 登録日 | 2022-08-23 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
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8AV6
 | | CryoEM structure of INO80 core nucleosome complex in closed grappler conformation | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DASH complex subunit DAD4, ... | | 著者 | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | | 登録日 | 2022-08-26 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (4.68 Å) | | 主引用文献 | Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
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6SKZ
 | | Structure of the closed conformation of CtTel1 | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase Tel1 | | 著者 | Jansma, M, Eustermann, S.E, Kostrewa, D, Lammens, K, Hopfner, K.P. | | 登録日 | 2019-08-16 | | 公開日 | 2019-10-30 | | 最終更新日 | 2020-01-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State.
Structure, 28, 2020
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6SL1
 | | Structure of the open conformation of CtTel1 | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase Tel1 | | 著者 | Jansma, M, Eustermann, S.E, Kostrewa, D, Lammens, K, Hopfner, K.P. | | 登録日 | 2019-08-16 | | 公開日 | 2019-10-30 | | 最終更新日 | 2020-05-13 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State.
Structure, 28, 2020
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3K1K
 | | Green fluorescent protein bound to enhancer nanobody | | 分子名称: | Enhancer, Green Fluorescent Protein | | 著者 | Kirchhofer, A, Helma, J, Schmidthals, K, Frauer, C, Cui, S, Karcher, A, Pellis, M, Muyldermans, S, Delucci, C.C, Cardoso, M.C, Leonhardt, H, Hopfner, K.-P, Rothbauer, U. | | 登録日 | 2009-09-28 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Modulation of protein properties in living cells using nanobodies
Nat.Struct.Mol.Biol., 17, 2010
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8A5P
 | | Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of Chaetomium thermophilum INO80 on curved DNA | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin related protein 4 (Arp4), ... | | 著者 | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | | 登録日 | 2022-06-15 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
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4WW4
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4YKE
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1KLI
 | | Cofactor-and substrate-assisted activation of factor VIIa | | 分子名称: | BENZAMIDINE, CALCIUM ION, GLYCEROL, ... | | 著者 | Sichler, K, Banner, D.W, D'Arcy, A, Hopfner, K.P, Huber, R, Bode, W, Kresse, G.B, Kopetzki, E, Brandstetter, H. | | 登録日 | 2001-12-12 | | 公開日 | 2002-09-18 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Crystal Structure of Uninhibited Factor VIIa Link its Cofactor and Substrate-assisted Activation to Specific Interactions
J.Mol.Biol., 322, 2002
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1KLJ
 | | Crystal structure of uninhibited factor VIIa | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, factor VIIa | | 著者 | Sichler, K, Banner, D, D'Arcy, A, Hopfner, K.P, Huber, R, Bode, W, Kresse, G.B, Kopetzki, E, Brandstetter, H. | | 登録日 | 2001-12-12 | | 公開日 | 2002-10-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Crystal structures of uninhibited factor VIIa link its cofactor and substrate-assisted activation to specific interactions.
J.Mol.Biol., 322, 2002
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8A5Q
 | | Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of Chaetomium thermophilum INO80 on straight DNA | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin related protein 4 (Arp4), ... | | 著者 | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | | 登録日 | 2022-06-15 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
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3C1Y
 | | Structure of bacterial DNA damage sensor protein with co-purified and co-crystallized ligand | | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, DNA integrity scanning protein disA | | 著者 | Witte, G, Hartung, S, Buttner, K, Hopfner, K.P. | | 登録日 | 2008-01-24 | | 公開日 | 2008-05-06 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Biochemistry of a Bacterial Checkpoint Protein Reveals Diadenylate Cyclase Activity Regulated by DNA Recombination Intermediates
Mol.Cell, 30, 2008
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3C21
 | | Structure of a bacterial DNA damage sensor protein with reaction product | | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, DNA integrity scanning protein disA | | 著者 | Witte, G, Hartung, S, Buttner, K, Hopfner, K.P. | | 登録日 | 2008-01-24 | | 公開日 | 2008-05-06 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural Biochemistry of a Bacterial Checkpoint Protein Reveals Diadenylate Cyclase Activity Regulated by DNA Recombination Intermediates
Mol.Cell, 30, 2008
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3C23
 | | Structure of a bacterial DNA damage sensor protein with non-reactive Ligand | | 分子名称: | 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, DNA integrity scanning protein disA | | 著者 | Witte, G, Hartung, S, Buttner, K, Hopfner, K.P. | | 登録日 | 2008-01-24 | | 公開日 | 2008-05-06 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural Biochemistry of a Bacterial Checkpoint Protein Reveals Diadenylate Cyclase Activity Regulated by DNA Recombination Intermediates
Mol.Cell, 30, 2008
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3KTA
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3C1Z
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3M7N
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3M85
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7Z8S
 | | Mot1:TBP:DNA - post hydrolysis state | | 分子名称: | DNA (36-MER), Helicase-like protein, Putative tata-box binding protein | | 著者 | Woike, S, Eustermann, S, Jung, J, Wenzl, S.J, Hagemann, G, Bartho, J.D, Lammens, K, Butryn, A, Herzog, F, Hopfner, K.-P. | | 登録日 | 2022-03-18 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1.
Nat.Struct.Mol.Biol., 30, 2023
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7Z7N
 | | Mot1E1434Q:TBP:DNA - substrate recognition state | | 分子名称: | DNA (36-MER), Helicase-like protein, Putative tata-box binding protein | | 著者 | Woike, S, Eustermann, S, Jung, J, Wenzl, S.J, Hagemann, G, Bartho, J.D, Lammens, K, Butryn, A, Herzog, F, Hopfner, K.-P. | | 登録日 | 2022-03-16 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (5.1 Å) | | 主引用文献 | Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1.
Nat.Struct.Mol.Biol., 30, 2023
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7ZB5
 | | Mot1(1-1836):TBP:DNA - post-hydrolysis complex dimer | | 分子名称: | DNA (36-MER), Helicase-like protein, Putative tata-box binding protein | | 著者 | Woike, S, Eustermann, S, Jung, J, Wenzl, S.J, Hagemann, G, Bartho, J.D, Lammens, K, Butryn, A, Herzog, F, Hopfner, K.-P. | | 登録日 | 2022-03-23 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1.
Nat.Struct.Mol.Biol., 30, 2023
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