6BWL
 
 | | X-ray structure of Pal from Bacillus thuringiensis | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | Authors: | Delvaux, N.A, Thoden, J.B, Holden, H.M. | | Deposit date: | 2017-12-15 | | Release date: | 2018-01-17 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Molecular architectures of Pen and Pal: Key enzymes required for CMP-pseudaminic acid biosynthesis in Bacillus thuringiensis.
Protein Sci., 27, 2018
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2NVW
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6CBK
 | | X-ray structure of NeoB from Streptomyces fradiae in complex with PMP | | Descriptor: | 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Neamine transaminase NeoN, ... | | Authors: | Thoden, J.B, Dow, G.T, Holden, H.M. | | Deposit date: | 2018-02-03 | | Release date: | 2018-03-07 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The three-dimensional structure of NeoB: An aminotransferase involved in the biosynthesis of neomycin.
Protein Sci., 27, 2018
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6CBL
 | | x-ray structure of NeoB from Streptomyces fradiae in complex with neamine as an external aldimine | | Descriptor: | (1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl 2-amino-2,6-dideoxy-6-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-alpha-D-glucopyranoside, CHLORIDE ION, Neamine transaminase NeoN | | Authors: | Thoden, J.B, Dow, G.T, Holden, H.M. | | Deposit date: | 2018-02-03 | | Release date: | 2018-02-21 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The three-dimensional structure of NeoB: An aminotransferase involved in the biosynthesis of neomycin.
Protein Sci., 27, 2018
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2PA7
 | | Structure of Wild-Type dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase from Aneurinibacillus thermoaerophilus in complex with TDP | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DTDP-6-deoxy-3,4-keto-hexulose isomerase, ... | | Authors: | Davis, M.L, Thoden, J.B, Holden, H.M. | | Deposit date: | 2007-03-27 | | Release date: | 2007-04-24 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The X-ray Structure of dTDP-4-Keto-6-deoxy-D-glucose-3,4-ketoisomerase.
J.Biol.Chem., 282, 2007
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6CBN
 | | x-ray structure of NeoB from streptomyces fradiae in complex with PLP and neomycin (as the external aldimine) at pH 7.5 | | Descriptor: | (1R,2R,3S,4R,6S)-4,6-diamino-2-[(3-O-{2-amino-2,6-dideoxy-6-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-alpha-D-glucopyranosyl}-beta-D-ribofuranosyl)oxy]-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside, 1,2-ETHANEDIOL, Neamine transaminase NeoN | | Authors: | Thoden, J.B, Dow, G.T, Holden, H.M. | | Deposit date: | 2018-02-03 | | Release date: | 2018-02-21 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | The three-dimensional structure of NeoB: An aminotransferase involved in the biosynthesis of neomycin.
Protein Sci., 27, 2018
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4LXQ
 | | Crystal structure WlaRD, a sugar 3N-formyl transferase in the presence of dTdp and 5-N-Formyl-THF | | Descriptor: | 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ... | | Authors: | Thoden, J.B, Goneau, M.-F, Gilbert, M, Holden, H.M. | | Deposit date: | 2013-07-30 | | Release date: | 2013-08-14 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structure of a sugar N-formyltransferase from Campylobacter jejuni.
Biochemistry, 52, 2013
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4LY3
 | | Crystal structure of WlaRD, a sugar 3N-formyl transferase in the presence of dTPD-Qui3N, dTDP-Qui3NFo, and THF | | Descriptor: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, N-[4-({[(6R)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, WlaRD a sugar 3N formyltransferase, ... | | Authors: | Thoden, J.B, Goneau, M.-F, Gilbert, M, Holden, H.M. | | Deposit date: | 2013-07-30 | | Release date: | 2013-08-14 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of a sugar N-formyltransferase from Campylobacter jejuni.
Biochemistry, 52, 2013
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6CBO
 | | X-ray structure of GenB1 from micromonospora echinospora in complex with neamine and PLP (as the external aldimine) | | Descriptor: | (1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl 2-amino-2,6-dideoxy-6-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-alpha-D-glucopyranoside, 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ... | | Authors: | Dow, G.T, Thoden, J.B, Holden, H.M. | | Deposit date: | 2018-02-03 | | Release date: | 2018-02-21 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The three-dimensional structure of NeoB: An aminotransferase involved in the biosynthesis of neomycin.
Protein Sci., 27, 2018
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4MZU
 | | Crystal structure of FdtD, a bifunctional ketoisomerase/N-acetyltransferase from Shewanella denitrificans | | Descriptor: | COENZYME A, MAGNESIUM ION, THYMIDINE-5'-DIPHOSPHATE, ... | | Authors: | Chantigian, D.P, Thoden, J.B, Holden, H.M. | | Deposit date: | 2013-09-30 | | Release date: | 2013-10-09 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural and Biochemical Characterization of a Bifunctional Ketoisomerase/N-Acetyltransferase from Shewanella denitrificans.
Biochemistry, 52, 2013
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6CBM
 | | x-ray structure of NeoB from streptomyces fradiae in complex with PLP and neomycin (as the external aldimine) at pH 9 | | Descriptor: | (1R,2R,3S,4R,6S)-4,6-diamino-2-[(3-O-{2-amino-2,6-dideoxy-6-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-alpha-D-glucopyranosyl}-beta-D-ribofuranosyl)oxy]-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside, 1,2-ETHANEDIOL, CHLORIDE ION, ... | | Authors: | Thoden, J.B, Dow, G.T, Holden, H.M. | | Deposit date: | 2018-02-03 | | Release date: | 2018-02-21 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | The three-dimensional structure of NeoB: An aminotransferase involved in the biosynthesis of neomycin.
Protein Sci., 27, 2018
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6BWC
 | | X-ray structure of Pen from Bacillus thuringiensis | | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Polysaccharide biosynthesis protein CapD, SULFATE ION, ... | | Authors: | Delvaux, N.A, Thoden, J.B, Holden, H.M. | | Deposit date: | 2017-12-14 | | Release date: | 2018-01-17 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Molecular architectures of Pen and Pal: Key enzymes required for CMP-pseudaminic acid biosynthesis in Bacillus thuringiensis.
Protein Sci., 27, 2018
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2PAK
 | | Structure of a H51N mutant dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase from Aneurinibacillus thermoaerophilus complexed with TDP | | Descriptor: | DTDP-6-deoxy-3,4-keto-hexulose isomerase, THYMIDINE-5'-DIPHOSPHATE | | Authors: | Davis, M.L, Thoden, J.B, Holden, H.M. | | Deposit date: | 2007-03-27 | | Release date: | 2007-04-24 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The X-ray Structure of dTDP-4-Keto-6-deoxy-D-glucose-3,4-ketoisomerase.
J.Biol.Chem., 282, 2007
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4LXX
 | | Crystal structure WlaRD, a sugar 3N-formyl transferase in the presence of dTDP-Fuc3NFo and 5-N-Formyl-THF | | Descriptor: | (2R,3R,4S,5R,6R)-4-(formylamino)-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name), 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ... | | Authors: | thoden, J.B, goneau, M.-F, gilbert, M, holden, H.M. | | Deposit date: | 2013-07-30 | | Release date: | 2013-08-14 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structure of a sugar N-formyltransferase from Campylobacter jejuni.
Biochemistry, 52, 2013
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4LXY
 | | Crystal structure WlaRD, a sugar 3N-formyl transferase in the presence of dTDP and 10-N-Formyl-THF | | Descriptor: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, N-{4-[{[(6S)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}(formyl)amino]benzoyl}-L-glutamic acid, THYMIDINE-5'-DIPHOSPHATE, ... | | Authors: | Thoden, J.B, Goneau, M.-F, Gilbert, M, Holden, H.M. | | Deposit date: | 2013-07-30 | | Release date: | 2013-08-14 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Structure of a sugar N-formyltransferase from Campylobacter jejuni.
Biochemistry, 52, 2013
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2PAM
 | | Structure of a H49N, H51N double mutant dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase from Aneurinibacillus thermoaerophilus complexed with TDP | | Descriptor: | DTDP-6-deoxy-3,4-keto-hexulose isomerase, THYMIDINE-5'-DIPHOSPHATE | | Authors: | Davis, M.L, Thoden, J.B, Holden, H.M. | | Deposit date: | 2007-03-27 | | Release date: | 2007-04-24 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The X-ray Structure of dTDP-4-Keto-6-deoxy-D-glucose-3,4-ketoisomerase.
J.Biol.Chem., 282, 2007
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2PAE
 | | Structure of a H49N mutant dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase from Aneurinibacillus thermoaerophilus in complex with TDP | | Descriptor: | DTDP-6-deoxy-3,4-keto-hexulose isomerase, THYMIDINE-5'-DIPHOSPHATE | | Authors: | Davis, M.L, Thoden, J.B, Holden, H.M. | | Deposit date: | 2007-03-27 | | Release date: | 2007-04-24 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The X-ray Structure of dTDP-4-Keto-6-deoxy-D-glucose-3,4-ketoisomerase.
J.Biol.Chem., 282, 2007
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2PO3
 | | Crystal Structure Analysis of DesI in the presence of its TDP-sugar product | | Descriptor: | (2R,3R,4S,5S,6R)-3,4-DIHYDROXY-5-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)IMINO]-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL [(2R,3S,5R)-3-HYDROXY-5-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)TETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE, 4-dehydrase | | Authors: | Burgie, E.S, Holden, H.M. | | Deposit date: | 2007-04-25 | | Release date: | 2007-08-14 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Molecular Architecture of DesI: A Key Enzyme in the Biosynthesis of Desosamine
Biochemistry, 46, 2007
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4NV1
 | | Crystal structure of a 4-N formyltransferase from Francisella tularensis | | Descriptor: | Formyltransferase, PHOSPHATE ION, THYMIDINE-5'-DIPHOSPHATE, ... | | Authors: | Thoden, J.B, Zimmer, A.L, Holden, H.M. | | Deposit date: | 2013-12-04 | | Release date: | 2013-12-25 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Three-dimensional structure of a sugar N-formyltransferase from Francisella tularensis.
Protein Sci., 23, 2014
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1WVC
 | | alpha-D-glucose-1-phosphate cytidylyltransferase complexed with CTP | | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, Glucose-1-phosphate cytidylyltransferase, MAGNESIUM ION, ... | | Authors: | Koropatkin, N.M, Cleland, W.W, Holden, H.M. | | Deposit date: | 2004-12-14 | | Release date: | 2005-01-11 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Kinetic and structural analysis of alpha-D-Glucose-1-phosphate cytidylyltransferase from Salmonella typhi.
J.Biol.Chem., 280, 2005
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1WUU
 | | crystal structure of human galactokinase complexed with MgAMPPNP and galactose | | Descriptor: | Galactokinase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Thoden, J.B, Timson, D.J, Reece, R.J, Holden, H.M. | | Deposit date: | 2004-12-08 | | Release date: | 2004-12-28 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Molecular Structure of Human Galactokinase: IMPLICATIONS FOR TYPE II GALACTOSEMIA
J.Biol.Chem., 280, 2005
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1WVG
 | | Structure of CDP-D-glucose 4,6-dehydratase from Salmonella typhi | | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, CDP-glucose 4,6-dehydratase, CYTIDINE-5'-DIPHOSPHO-BETA-D-XYLOSE | | Authors: | Koropatkin, N.M, Holden, H.M. | | Deposit date: | 2004-12-15 | | Release date: | 2005-01-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of CDP-D-glucose 4,6-dehydratase from Salmonella typhi complexed with CDP-D-xylose.
Acta Crystallogr.,Sect.D, 61, 2005
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3NDI
 | | X-ray Structure of a C-3'-Methyltransferase in Complex with S-adenosylmethionine and dTMP | | Descriptor: | Methyltransferase, PHOSPHATE ION, S-ADENOSYLMETHIONINE, ... | | Authors: | Bruender, N.A, Thoden, J.B, Kaur, M, Avey, M.K, Holden, H.M. | | Deposit date: | 2010-06-07 | | Release date: | 2010-06-30 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Molecular Architecture of a C-3'-Methyltransferase Involved in the Biosynthesis of d-Tetronitrose.
Biochemistry, 49, 2010
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3NDJ
 | | X-ray Structure of a C-3'-Methyltransferase in Complex with S-Adenosyl-L-Homocysteine and Sugar Product | | Descriptor: | (2R,4S,6R)-4-amino-4,6-dimethyl-5-oxotetrahydro-2H-pyran-2-yl [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name), Methyltransferase, PHOSPHATE ION, ... | | Authors: | Bruender, N.A, Thoden, J.B, Kaur, M, Avey, M.K, Holden, H.M. | | Deposit date: | 2010-06-07 | | Release date: | 2010-06-30 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Molecular Architecture of a C-3'-Methyltransferase Involved in the Biosynthesis of d-Tetronitrose.
Biochemistry, 49, 2010
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3MQG
 | | crystal structure of the 3-N-acetyl transferase WlbB from Bordetella petrii in complex with acetyl-CoA | | Descriptor: | 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ACETYL COENZYME *A, ... | | Authors: | Thoden, J.B, Holden, H.M. | | Deposit date: | 2010-04-28 | | Release date: | 2010-05-12 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.43 Å) | | Cite: | Molecular structure of WlbB, a bacterial N-acetyltransferase involved in the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid .
Biochemistry, 49, 2010
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