6CBL
x-ray structure of NeoB from Streptomyces fradiae in complex with neamine as an external aldimine
Summary for 6CBL
| Entry DOI | 10.2210/pdb6cbl/pdb |
| Descriptor | Neamine transaminase NeoN, (1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl 2-amino-2,6-dideoxy-6-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-alpha-D-glucopyranoside, CHLORIDE ION, ... (4 entities in total) |
| Functional Keywords | neomycin, aminotransferase, transferase |
| Biological source | Streptomyces fradiae (Streptomyces roseoflavus) |
| Total number of polymer chains | 8 |
| Total formula weight | 370595.62 |
| Authors | Thoden, J.B.,Dow, G.T.,Holden, H.M. (deposition date: 2018-02-03, release date: 2018-02-21, Last modification date: 2023-10-04) |
| Primary citation | Dow, G.T.,Thoden, J.B.,Holden, H.M. The three-dimensional structure of NeoB: An aminotransferase involved in the biosynthesis of neomycin. Protein Sci., 27:945-956, 2018 Cited by PubMed: 29516565DOI: 10.1002/pro.3400 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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