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PDB: 72 件
8OG4
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Exostosin-like 3 UDP complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Exostosin-like 3, MANGANESE (II) ION, ...
著者Sammon, D, Hohenester, E.
登録日2023-03-18
公開日2023-07-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular mechanism of decision-making in glycosaminoglycan biosynthesis.
Nat Commun, 14, 2023
8OG1
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Exostosin-like 3 apo enzyme
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Exostosin-like 3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Sammon, D, Hohenester, E.
登録日2023-03-17
公開日2023-07-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Molecular mechanism of decision-making in glycosaminoglycan biosynthesis.
Nat Commun, 14, 2023
5IK5
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Laminin A2LG45 C-form, G6/7 bound.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-hydroxy-4-methyl-2H-chromen-2-one, CALCIUM ION, ...
著者Briggs, D.C, Hohenester, E, Campbell, K.P.
登録日2016-03-03
公開日2016-08-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Nat.Chem.Biol., 12, 2016
5IK8
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Laminin A2LG45 I-form, G6/7 bound.
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-hydroxy-4-methyl-2H-chromen-2-one, ...
著者Briggs, D.C, Hohenester, E, Campbell, K.P.
登録日2016-03-03
公開日2016-08-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Nat.Chem.Biol., 12, 2016
2C5D
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Structure of a minimal Gas6-Axl complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GROWTH-ARREST-SPECIFIC PROTEIN 6 PRECURSOR, ...
著者Sasaki, T, Knyazev, P.G, Clout, N.J, Cheburkin, Y, Goehring, W, Ullrich, A, Timpl, R, Hohenester, E.
登録日2005-10-26
公開日2005-12-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural Basis for Gas6-Axl Signalling.
Embo J., 25, 2006
5AO5
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Endo180 D1-4, monoclinic form
分子名称: C-TYPE MANNOSE RECEPTOR 2, SODIUM ION, SULFATE ION
著者Paracuellos, P, Briggs, D.C, Carafoli, F, Loncar, T, Hohenester, E.
登録日2015-09-09
公開日2015-10-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Insights Into Collagen Uptake by C-Type Mannose Receptors from the Crystal Structure of Endo180 Domains 1-4.
Structure, 23, 2015
5AO6
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Endo180 D1-4, trigonal form
分子名称: C-TYPE MANNOSE RECEPTOR 2
著者Paracuellos, P, Briggs, D.C, Carafoli, F, Loncar, T, Hohenester, E.
登録日2015-09-09
公開日2015-10-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.36 Å)
主引用文献Insights Into Collagen Uptake by C-Type Mannose Receptors from the Crystal Structure of Endo180 Domains 1-4.
Structure, 23, 2015
2DKB
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DIALKYLGLYCINE DECARBOXYLASE STRUCTURE: BIFUNCTIONAL ACTIVE SITE AND ALKALI METAL BINDING SITES
分子名称: 2,2-DIALKYLGLYCINE DECARBOXYLASE (PYRUVATE), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PYRIDOXAL-5'-PHOSPHATE, ...
著者Toney, M.D, Hohenester, E, Jansonius, J.N.
登録日1994-07-12
公開日1994-10-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Dialkylglycine decarboxylase structure: bifunctional active site and alkali metal sites.
Science, 261, 1993
1GL4
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Nidogen-1 G2/Perlecan IG3 Complex
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN, NIDOGEN-1, ...
著者Kvansakul, M, Hopf, M, Ries, A, Timpl, R, Hohenester, E.
登録日2001-08-23
公開日2001-11-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for the High-Affinity Interaction of Nidogen-1 with Immunoglobulin-Like Domain 3 of Perlecan
Embo J., 20, 2001
1GR3
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Structure of the human collagen X NC1 trimer
分子名称: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CALCIUM ION, COLLAGEN X, ...
著者Bogin, O, Kvansakul, M, Rom, E, Singer, J, Yayon, A, Hohenester, E.
登録日2001-12-12
公開日2002-02-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insight Into Schmid Metaphyseal Chondrodysplasia from the Crystal Structure of the Collagen X Nc1 Domain Trimer.
Structure, 10, 2002
5LF2
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Crystal structure of laminin beta2 LE5-LF-LE6
分子名称: CALCIUM ION, CHLORIDE ION, Laminin subunit beta-2
著者Pulido, D, Hohenester, E.
登録日2016-06-30
公開日2016-07-27
最終更新日2017-03-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystallographic analysis of the laminin beta 2 short arm reveals how the LF domain is inserted into a regular array of LE domains.
Matrix Biol., 57-58, 2017
5MX1
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BU of 5mx1 by Molmil
Crystal structure of human chondroadherin
分子名称: CHLORIDE ION, Chondroadherin, NICKEL (II) ION, ...
著者Paracuellos, P, Hohenester, E.
登録日2017-01-20
公開日2017-03-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural and functional analysis of two small leucine-rich repeat proteoglycans, fibromodulin and chondroadherin.
Matrix Biol., 63, 2017
5MC9
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Crystal structure of the heterotrimeric integrin-binding region of laminin-111
分子名称: CALCIUM ION, Laminin subunit alpha-1, Laminin subunit beta-1, ...
著者Pulido, D, Hohenester, E.
登録日2016-11-09
公開日2017-02-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Crystal Structure of the Heterotrimeric Integrin-Binding Region of Laminin-111.
Structure, 25, 2017
5MX0
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Crystal structure of human fibromodulin
分子名称: CHLORIDE ION, Fibromodulin, NICKEL (II) ION, ...
著者Paracuellos, P, Hohenester, E.
登録日2017-01-20
公開日2017-03-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structural and functional analysis of two small leucine-rich repeat proteoglycans, fibromodulin and chondroadherin.
Matrix Biol., 63, 2017
1H30
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BU of 1h30 by Molmil
C-terminal LG domain pair of human Gas6
分子名称: CALCIUM ION, GROWTH-ARREST-SPECIFIC PROTEIN, SULFATE ION
著者Sasaki, T, Knyazev, P.G, Cheburkin, Y, Gohring, W, Tisi, D, Ullrich, A, Timpl, R, Hohenester, E.
登録日2002-08-21
公開日2003-01-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of a Carboxy-Terminal Fragment of Growth-Arrest-Specific Protein Gas6: Receptor Tyrosine Kinase Activation by Laminin G-Like Domains
J.Biol.Chem., 277, 2002
4AUO
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Crystal structure of MMP-1(E200A) in complex with a triple-helical collagen peptide
分子名称: CALCIUM ION, INTERSTITIAL COLLAGENASE, TRIPLE-HELICAL COLLAGEN PEPTIDE, ...
著者Manka, S.W, Carafoli, F, Visse, R, Bihan, D, Raynal, N, Farndale, R.W, Murphy, G, Enghild, J.J, Hohenester, E, Nagase, H.
登録日2012-05-18
公開日2012-07-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Insights Into Triple-Helical Collagen Cleavage by Matrix Metalloproteinase 1
Proc.Natl.Acad.Sci.USA, 109, 2012
1H4U
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Domain G2 of mouse nidogen-1
分子名称: NIDOGEN-1
著者Hopf, M, Gohring, W, Ries, A, Timpl, R, Hohenester, E.
登録日2001-05-14
公開日2001-06-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure and Mutational Analysis of a Perlecan-Binding Fragment of Nidogen-1
Nat.Struct.Biol., 8, 2001
4BJ3
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BU of 4bj3 by Molmil
Integrin alpha2 I domain E318W-collagen complex
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GFOGER PEPTIDE, ...
著者Carafoli, F, Hamaia, S.W, Bihan, D, Hohenester, E, Farndale, R.W.
登録日2013-04-16
公開日2013-11-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.042 Å)
主引用文献An Activating Mutation Reveals a Second Binding Mode of the Integrin Alpha2 I Domain to the Gfoger Motif in Collagens.
Plos One, 8, 2013
1O91
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Crystal Structure of a Collagen VIII NC1 Domain Trimer
分子名称: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, COLLAGEN ALPHA 1(VIII) CHAIN, SULFATE ION
著者Kvansakul, M, Bogin, O, Hohenester, E, Yayon, A.
登録日2002-12-10
公開日2003-11-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of the Collagen Alpha1(Viii) Nc1 Trimer.
Matrix Biol., 22, 2003
4AG4
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Crystal structure of a DDR1-Fab complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1, ...
著者Carafoli, F, Mayer, M.C, Shiraishi, K, Pecheva, M.A, Chan, L.Y, Nan, R, Leitinger, B, Hohenester, E.
登録日2012-01-24
公開日2012-04-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the Discoidin Domain Receptor 1 Extracellular Region Bound to an Inhibitory Fab Fragment Reveals Features Important for Signaling.
Structure, 20, 2012
1UX6
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Structure of a thrombospondin C-terminal fragment reveals a novel calcium core in the type 3 repeats
分子名称: CALCIUM ION, THROMBOSPONDIN-1
著者Kvansakul, M, Adams, J.C, Hohenester, E.
登録日2004-02-19
公開日2004-03-18
最終更新日2017-07-12
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of a Thrombospondin C-Terminal Fragment Reveals a Novel Calcium Core in the Type 3 Repeats
Embo J., 23, 2004
2WUH
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BU of 2wuh by Molmil
Crystal structure of the DDR2 discoidin domain bound to a triple- helical collagen peptide
分子名称: COLLAGEN PEPTIDE, DISCOIDIN DOMAIN RECEPTOR 2
著者Carafoli, F, Bihan, D, Stathopoulos, S, Konitsiotis, A.D, Kvansakul, M, Farndale, R.W, Leitinger, B, Hohenester, E.
登録日2009-10-05
公開日2009-12-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystallographic Insight Into Collagen Recognition by Discoidin Domain Receptor 2
Structure, 17, 2009
1OKQ
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LAMININ ALPHA 2 CHAIN LG4-5 DOMAIN PAIR, CA1 SITE MUTANT
分子名称: CALCIUM ION, LAMININ ALPHA 2 CHAIN
著者Wizemann, H, Garbe, J.H.O, Friedrich, M.V.K, Timpl, R, Sasaki, T, Hohenester, E.
登録日2003-07-28
公開日2003-09-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Distinct Requirements for Heparin and Alpha-Dystroglycan Binding Revealed by Structure-Based Mutagenesis of the Laminin Alpha2 Lg4-Lg5 Domain Pair
J.Mol.Biol., 332, 2003
1B8G
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1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE
分子名称: PROTEIN (1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE), PYRIDOXAL-5'-PHOSPHATE
著者Capitani, G, Hohenester, E, Feng, L, Storici, P, Kirsch, J.F, Jansonius, J.N.
登録日1999-01-31
公開日2000-01-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structure of 1-aminocyclopropane-1-carboxylate synthase, a key enzyme in the biosynthesis of the plant hormone ethylene.
J.Mol.Biol., 294, 1999
4AQT
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Laminin gamma1 LN-LE1-2 structure
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, LAMININ SUBUNIT GAMMA-1, ...
著者Carafoli, F, Hussain, S, Hohenester, E.
登録日2012-04-19
公開日2012-08-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal Structures of the Network-Forming Short-Arm Tips of the Laminin Beta1 and Gamma1 Chains.
Plos One, 7, 2012

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