7RZY
| CryoEM structure of Vibrio cholerae transposon Tn6677 AAA+ ATPase TnsC | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Tn6677 Vibrio cholerae transposon TnsC (VchTnsC) | 著者 | Hoffmann, F.T, Kim, M, Beh, L.Y, Wang, J, Vo, P.L.H, Gelsinger, D.R, Acree, C, Mohabir, J.T, Fernandez, I.S, Sternberg, S.H. | 登録日 | 2021-08-28 | 公開日 | 2022-06-08 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Selective TnsC recruitment enhances the fidelity of RNA-guided transposition. Nature, 609, 2022
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4MN3
| Chromodomain antagonists that target the polycomb-group methyllysine reader protein Chromobox homolog 7 (CBX7) | 分子名称: | 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Chromobox protein homolog 7, ... | 著者 | Chakravarthi, S, Daze, K, Douglas, S, Quon, T, Dev, A, Peng, F, Heller, M, Boulanger, M.J, Wulff, J, Hof, F. | 登録日 | 2013-09-09 | 公開日 | 2014-04-02 | 最終更新日 | 2014-10-08 | 実験手法 | X-RAY DIFFRACTION (1.542 Å) | 主引用文献 | Chromodomain Antagonists That Target the Polycomb-Group Methyllysine Reader Protein Chromobox Homolog 7 (CBX7). J.Med.Chem., 57, 2014
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5FPX
| The structure of KdgF from Yersinia enterocolitica. | 分子名称: | NICKEL (II) ION, PECTIN DEGRADATION PROTEIN, PEPTIDE | 著者 | Hobbs, J.K, Lee, S.M, Robb, M, Hof, F, Barr, C, Abe, K.T, Hehemann, J.H, McLean, R, Abbott, D.W, Boraston, A.B. | 登録日 | 2015-12-03 | 公開日 | 2016-05-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Kdgf, the Missing Link in the Microbial Metabolism of Uronate Sugars from Pectin and Alginate. Proc.Natl.Acad.Sci.USA, 113, 2016
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5FQ0
| The structure of KdgF from Halomonas sp. | 分子名称: | CITRATE ANION, KDGF, NICKEL (II) ION, ... | 著者 | Hobbs, J.K, Lee, S.M, Robb, M, Hof, F, Barr, C, Abe, K.T, Hehemann, J.H, McLean, R, Abbott, D.W, Boraston, A.B. | 登録日 | 2015-12-03 | 公開日 | 2016-05-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Kdgf, the Missing Link in the Microbial Metabolism of Uronate Sugars from Pectin and Alginate. Proc.Natl.Acad.Sci.USA, 113, 2016
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5FPZ
| The structure of KdgF from Yersinia enterocolitica with malonate bound in the active site. | 分子名称: | MALONIC ACID, NICKEL (II) ION, PECTIN DEGRADATION PROTEIN | 著者 | Hobbs, J.K, Lee, S.M, Robb, M, Hof, F, Barr, C, Abe, K.T, Hehemann, J.H, McLean, R, Abbott, D.W, Boraston, A.B. | 登録日 | 2015-12-03 | 公開日 | 2016-05-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Kdgf, the Missing Link in the Microbial Metabolism of Uronate Sugars from Pectin and Alginate. Proc.Natl.Acad.Sci.USA, 113, 2016
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4AQJ
| Structure of human S100A7 D24G bound to zinc and calcium | 分子名称: | CALCIUM ION, CHLORIDE ION, PROTEIN S100-A7, ... | 著者 | Murray, J.I, Tonkin, M.L, Whiting, A.L, Peng, F, Farnell, B, Hof, F, Boulanger, M.J. | 登録日 | 2012-04-17 | 公開日 | 2012-10-17 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Characterization of S100A15 Reveals a Novel Zinc Coordination Site Among S100 Proteins and Altered Surface Chemistry with Functional Implications for Receptor Binding. Bmc Struct.Biol., 12, 2012
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4AQI
| Structure of human S100A15 bound to zinc and calcium | 分子名称: | CALCIUM ION, CHLORIDE ION, PROTEIN S100-A7A, ... | 著者 | Murray, J.I, Tonkin, M.L, Whiting, A.L, Peng, F, Farnell, B, Hof, F, Boulanger, M.J. | 登録日 | 2012-04-17 | 公開日 | 2012-10-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Characterization of S100A15 Reveals a Novel Zinc Coordination Site Among S100 Proteins and Altered Surface Chemistry with Functional Implications for Receptor Binding. Bmc Struct.Biol., 12, 2012
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2WOS
| Structure of human S100A7 in complex with 2,6 ANS | 分子名称: | 6-[(1E)-CYCLOHEXA-2,4-DIEN-1-YLIDENEAMINO]NAPHTHALENE-2-SULFONATE, CALCIUM ION, PROTEIN S100-A7, ... | 著者 | Leon, R, Murray, J.I, Cragg, G, Farnell, B, Pace, T.C, Bohne, C, Boulanger, M.J, Hof, F. | 登録日 | 2009-07-27 | 公開日 | 2009-10-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Identification and Characterization of Binding Sites on S100A7, a Participant in Cancer and Inflammation Pathways. Biochemistry, 48, 2009
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2WOR
| co-structure of S100A7 with 1,8 ANS | 分子名称: | 8-ANILINO-1-NAPHTHALENE SULFONATE, CALCIUM ION, PROTEIN S100-A7, ... | 著者 | Leon, R, Hof, F, Boulanger, M.J. | 登録日 | 2009-07-27 | 公開日 | 2009-10-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Identification and Characterization of Binding Sites on S100A7, a Participant in Cancer and Inflammation Pathways. Biochemistry, 48, 2009
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4V8P
| T.thermophila 60S ribosomal subunit in complex with initiation factor 6. | 分子名称: | 26S RRNA, 5.8S RRNA, 5S RRNA, ... | 著者 | Klinge, S, Voigts-Hoffmann, F, Leibundgut, M, Arpagaus, S, Ban, N. | 登録日 | 2011-09-14 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.52 Å) | 主引用文献 | Crystal Structure of the Eukaryotic 60S Ribosomal Subunit in Complex with Initiation Factor 6. Science, 334, 2011
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6JT4
| Crystal Structure of BACE1 in complex with N-{3-[(4S,6S)-2-amino-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-thiazin-4-yl]-4-fluorophenyl}-5-(fluoromethoxy)pyrazine-2-carboxamide | 分子名称: | Beta-secretase 1, GLYCEROL, IODIDE ION, ... | 著者 | Anan, K, Iso, Y, Oguma, T, Nakahara, K, Suzuki, S, Yamamoto, T, Matsuoka, E, Ito, H, Sakaguchi, G, Ando, S, Morimoto, K, Kanegawa, N, Kido, Y, Kawachi, T, Fukushima, T, Teisman, A, Urmaliya, V, Dhuyvetter, D, Borghys, H, Austin, N, Bergh, A.V.D, Verboven, P, Bischoff, F, Gijsen, H.J.M, Yamano, Y, Kusakabe, K.I. | 登録日 | 2019-04-08 | 公開日 | 2020-01-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Trifluoromethyl Dihydrothiazine-Based beta-Secretase (BACE1) Inhibitors with Robust Central beta-Amyloid Reduction and Minimal Covalent Binding Burden. Chemmedchem, 14, 2019
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7VKV
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4BTS
| THE CRYSTAL STRUCTURE OF THE EUKARYOTIC 40S RIBOSOMAL SUBUNIT IN COMPLEX WITH EIF1 AND EIF1A | 分子名称: | 18S ribosomal RNA, 40S RIBOSOMAL PROTEIN RACK1, 40S RIBOSOMAL PROTEIN RPS10E, ... | 著者 | Weisser, M, Voigts-Hoffmann, F, Rabl, J, Leibundgut, M, Ban, N. | 登録日 | 2013-06-19 | 公開日 | 2013-07-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.703 Å) | 主引用文献 | The crystal structure of the eukaryotic 40S ribosomal subunit in complex with eIF1 and eIF1A. Nat. Struct. Mol. Biol., 20, 2013
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4CE4
| 39S large subunit of the porcine mitochondrial ribosome | 分子名称: | 16S Ribosomal RNA, ICT1, MRPL13, ... | 著者 | Greber, B.J, Boehringer, D, Leitner, A, Bieri, P, Voigts-Hoffmann, F, Erzberger, J.P, Leibundgut, M, Aebersold, R, Ban, N. | 登録日 | 2013-11-08 | 公開日 | 2013-12-18 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Architecture of the Large Subunit of the Mammalian Mitochondrial Ribosome. Nature, 505, 2014
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4C7O
| The structural basis of FtsY recruitment and GTPase activation by SRP RNA | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SIGNAL RECOGNITION PARTICLE PROTEIN, ... | 著者 | Voigts-Hoffmann, F, Schmitz, N, Shen, K, Shan, S.O, Ataide, S.F, Ban, N. | 登録日 | 2013-09-23 | 公開日 | 2013-11-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The Structural Basis of Ftsy Recruitment and Gtpase Activation by Srp RNA Mol.Cell, 52, 2013
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1LXD
| CRYSTAL STRUCTURE OF THE RAS INTERACTING DOMAIN OF RALGDS, A GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR OF RAL PROTEIN | 分子名称: | RALGDSB | 著者 | Huang, L, Weng, X.W, Hofer, F, Martin, G.S, Kim, S.H. | 登録日 | 1997-03-05 | 公開日 | 1998-03-11 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Three-dimensional structure of the Ras-interacting domain of RalGDS. Nat.Struct.Biol., 4, 1997
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1LFD
| CRYSTAL STRUCTURE OF THE ACTIVE RAS PROTEIN COMPLEXED WITH THE RAS-INTERACTING DOMAIN OF RALGDS | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, RALGDS, ... | 著者 | Huang, L, Hofer, F, Martin, G.S, Kim, S.-H. | 登録日 | 1998-04-29 | 公開日 | 1999-05-04 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for the interaction of Ras with RalGDS. Nat.Struct.Biol., 5, 1998
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2L6T
| Efficacy of an HIV-1 entry inhibitor targeting the GP41 fusion peptide | 分子名称: | VIR-576 | 著者 | Forssmann, W, The, Y, Stoll, M, Adermann, K, Albrecht, U, Barlos, K, Busmann, A, Can les-Mayordomo, A, Gimenez-Gallego, G, Hirsch, J, Jimenez-Barbero, J, Meyer-Olson, D, Muench, J, Perez-Castells, J, Staendker, L, Kirchhoff, F, Schmidt, R.E. | 登録日 | 2010-11-24 | 公開日 | 2011-01-19 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide. Sci Transl Med, 2, 2010
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2JNR
| Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide | 分子名称: | ENV polyprotein, VIR165 | 著者 | Munch, J, Standker, L, Adermann, K, Schulz, A, Pohlmann, S, Chaipan, C, Biet, T, Peters, T, Meyer, B, Wilhelm, D, Lu, H, Jing, W, Jiang, S, Forssmann, W, Kirchhoff, F. | 登録日 | 2007-02-01 | 公開日 | 2007-05-08 | 最終更新日 | 2023-12-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Discovery and Optimization of a Natural HIV-1 Entry Inhibitor Targeting the gp41 Fusion Peptide. Cell(Cambridge,Mass.), 129, 2007
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2L6S
| Efficacy of an HIV-1 entry inhibitor targeting the GP41 fusion peptide | 分子名称: | VIR-576 | 著者 | Forssmann, W, The, Y, Stoll, M, Adermann, K, Albrecht, U, Barlos, K, Busmann, A, Canales-Mayordomo, A, Gimenez-Gallego, G, Hirsch, J, Jimenez-Barbero, J, Meyer-Olson, D, Muench, J, Perez-Castells, J, Standker, L, Kirchhoff, F, Schmidt, R.E. | 登録日 | 2010-11-24 | 公開日 | 2011-01-19 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide. Sci Transl Med, 2, 2010
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4PHH
| Crystal structure of Ypt7 covalently modified with GNP | 分子名称: | 5'-O-[(R)-hydroxy{[(S)-hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]-N-[3-(propanoylamino)propyl]guanosine, CHLORIDE ION, GTP-binding protein YPT7, ... | 著者 | Wiegandt, D, Vieweg, S, Hofmann, F, Koch, D, Wu, Y, Itzen, A, Mueller, M.P, Goody, R.S. | 登録日 | 2014-05-06 | 公開日 | 2014-05-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Locking GTPases covalently in their functional states. Nat Commun, 6, 2015
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4PHG
| Crystal structure of Ypt7 covalently modified with GTP | 分子名称: | GTP-binding protein YPT7, MAGNESIUM ION, N-[3-(propanoylamino)propyl]guanosine 5'-(tetrahydrogen triphosphate), ... | 著者 | Koch, D, Wiegandt, D, Vieweg, S, Hofmann, F, Wu, Y, Itzen, A, Mueller, M.P, Goody, R.S. | 登録日 | 2014-05-06 | 公開日 | 2014-05-28 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Locking GTPases covalently in their functional states. Nat Commun, 6, 2015
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4PHF
| Crystal structure of Ypt7 covalently modified with GDP | 分子名称: | GTP-binding protein YPT7, MAGNESIUM ION, N-[3-(propanoylamino)propyl]guanosine 5'-(trihydrogen diphosphate), ... | 著者 | Vieweg, S, Wiegandt, D, Hofmann, F, Koch, D, Wu, Y, Itzen, A, Mueller, M.P, Goody, R.S. | 登録日 | 2014-05-06 | 公開日 | 2014-05-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Locking GTPases covalently in their functional states. Nat Commun, 6, 2015
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6Y3H
| NMR solution structure of the hazelnut allergen Cor a 1.0401 | 分子名称: | Major allergen Cor a 1.0401 | 著者 | Fuehrer, S, Kamenik, A.S, Zeindl, R, Nothegger, B, Hofer, F, Reider, N, Liedl, K.R, Tollinger, M. | 登録日 | 2020-02-18 | 公開日 | 2021-02-17 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Inverse relation between structural flexibility and IgE reactivity of Cor a 1 hazelnut allergens. Sci Rep, 11, 2021
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6Y3L
| NMR solution structure of the hazelnut allergen Cor a 1.0404 | 分子名称: | Major allergen variant Cor a 1.0404 | 著者 | Fuehrer, S, Kamenik, A.S, Zeindl, R, Nothegger, B, Hofer, F, Reider, N, Liedl, K.R, Tollinger, M. | 登録日 | 2020-02-18 | 公開日 | 2021-02-17 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Inverse relation between structural flexibility and IgE reactivity of Cor a 1 hazelnut allergens. Sci Rep, 11, 2021
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