1U5T
 
 | | Structure of the ESCRT-II endosomal trafficking complex | | 分子名称: | Defective in vacuolar protein sorting; Vps36p, Hypothetical 23.6 kDa protein in YUH1-URA8 intergenic region, appears to be functionally related to SNF7; Snf8p | | 著者 | Hierro, A, Sun, J, Rusnak, A.S, Kim, J, Prag, G, Emr, S.D, Hurley, J.H. | | 登録日 | 2004-07-28 | | 公開日 | 2004-09-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structure of ESCRT-II endosomal trafficking complex
Nature, 431, 2004
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2R17
 | | Functional architecture of the retromer cargo-recognition complex | | 分子名称: | GLYCEROL, Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35 | | 著者 | Hierro, A, Rojas, A.L, Rojas, R, Murthy, N, Effantin, G, Kajava, A.V, Steven, A.C, Bonifacino, J.S, Hurley, J.H. | | 登録日 | 2007-08-22 | | 公開日 | 2007-10-30 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Functional architecture of the retromer cargo-recognition complex.
Nature, 449, 2007
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5OT4
 | | Structure of the Legionella pneumophila effector RidL (1-866) | | 分子名称: | GLYCEROL, Interaptin | | 著者 | Romano-Moreno, M, Rojas, A.L, Lucas, M, Isupov, M.N, Hierro, A. | | 登録日 | 2017-08-20 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Molecular mechanism for the subversion of the retromer coat by the Legionella effector RidL.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8RKS
 | | Structure of VPS29-VPS35 bound to the LFa motif R21 of Fam21. | | 分子名称: | Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35, WASH complex subunit 2A | | 著者 | Romano-Moreno, M, Astorga-Simon, E.N, Rojas, A.L, Hierro, A. | | 登録日 | 2023-12-30 | | 公開日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Retromer-mediated recruitment of the WASH complex involves discrete interactions between VPS35, VPS29, and FAM21.
Protein Sci., 33, 2024
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1ZB1
 | | Structure basis for endosomal targeting by the Bro1 domain | | 分子名称: | BRO1 protein | | 著者 | Kim, J, Sitaraman, S, Hierro, A, Beach, B.M, Odorizzi, G, Hurley, J.H. | | 登録日 | 2005-04-07 | | 公開日 | 2005-06-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural basis for endosomal targeting by the Bro1 domain.
Dev.Cell, 8, 2005
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6RRE
 | | SidD, deAMPylase from Legionella pneumophila | | 分子名称: | Adenosine monophosphate-protein hydrolase SidD, MAGNESIUM ION | | 著者 | Tascon, I, Lucas, M, Rojas, A.L, Hierro, A. | | 登録日 | 2019-05-17 | | 公開日 | 2020-10-07 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (3.586 Å) | | 主引用文献 | Structural insight into the membrane targeting domain of the Legionella deAMPylase SidD.
Plos Pathog., 16, 2020
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3N1B
 | | C-terminal domain of Vps54 subunit of the GARP complex | | 分子名称: | Vacuolar protein sorting-associated protein 54 | | 著者 | Perez-Victoria, F.J, Abascal-Palacios, G, Tascon, I, Kajava, A, Pioro, E.P, Bonifacino, J.S, Hierro, A. | | 登録日 | 2010-05-15 | | 公開日 | 2010-07-14 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.398 Å) | | 主引用文献 | Structural basis for the wobbler mouse neurodegenerative disorder caused by mutation in the Vps54 subunit of the GARP complex.
Proc.Natl.Acad.Sci.USA, 107, 2010
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6RP4
 | | CDT of SidD, deAMPylase from Legionella pneumophila | | 分子名称: | Adenosine monophosphate-protein hydrolase SidD, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Tascon, I, Lucas, M, Rojas, A.L, Hierro, A. | | 登録日 | 2019-05-13 | | 公開日 | 2020-10-07 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural insight into the membrane targeting domain of the Legionella deAMPylase SidD.
Plos Pathog., 16, 2020
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3N1E
 | | Vps54 C-terminal domain | | 分子名称: | GLYCEROL, MAGNESIUM ION, Vacuolar protein sorting-associated protein 54 | | 著者 | Perez-Victoria, F.J, Abascal-Palacios, G, Tascon, I, Kajava, A, Pioro, E.P, Bonifacino, J.S, Hierro, A. | | 登録日 | 2010-05-15 | | 公開日 | 2010-07-14 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | | 主引用文献 | Structural basis for the wobbler mouse neurodegenerative disorder caused by mutation in the Vps54 subunit of the GARP complex.
Proc.Natl.Acad.Sci.USA, 107, 2010
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5OSI
 | | Structure of retromer VPS29-VPS35C subunits complexed with RidL harpin loop (163-176) | | 分子名称: | 1,2-ETHANEDIOL, Interaptin, SODIUM ION, ... | | 著者 | Romano-Moreno, M, Rojas, A.L, Lucas, M, Isupov, M.N, Hierro, A. | | 登録日 | 2017-08-17 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | Molecular mechanism for the subversion of the retromer coat by the Legionella effector RidL.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5OSH
 | | Structure of retromer VPS29-VPS35C subunits complexed with RidL N-terminal domain (1-236) | | 分子名称: | Interaptin, Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35 | | 著者 | Romano-Moreno, M, Rojas, A.L, Lucas, M, Isupov, M.N, Hierro, A. | | 登録日 | 2017-08-17 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | | 主引用文献 | Molecular mechanism for the subversion of the retromer coat by the Legionella effector RidL.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5MIY
 | | Crystal structure of the E3 ubiquitin ligase RavN from Legionella pneumophila | | 分子名称: | 1,2-ETHANEDIOL, E3 ubiquitin ligase RavN, SODIUM ION, ... | | 著者 | Lucas, M, Abascal-Palacios, G, Rojas, A.L, Hierro, A. | | 登録日 | 2016-11-29 | | 公開日 | 2018-05-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.717 Å) | | 主引用文献 | RavN is a member of a previously unrecognized group of Legionella pneumophila E3 ubiquitin ligases.
PLoS Pathog., 14, 2018
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8A1G
 | | Structure of the SNX1-SNX5 complex | | 分子名称: | N-PROPANOL, Sorting nexin-1, Sorting nexin-5 | | 著者 | Lopez-Robles, C, Scaramuzza, S, Astorga-Simon, E.N, Banos-Mateos, S, Vidaurrazaga, A, Rojas, A.L, Castano, D, Hierro, A. | | 登録日 | 2022-06-01 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Architecture of the ESCPE-1 membrane coat.
Nat.Struct.Mol.Biol., 30, 2023
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4J2C
 | | GARP-SNARE Interaction | | 分子名称: | Syntaxin-6, Vacuolar protein sorting-associated protein 51 homolog | | 著者 | Abascal-Palacios, G, Schindler, C, Rojas, A.L, Bonifacino, J.S, Hierro, A. | | 登録日 | 2013-02-04 | | 公開日 | 2013-12-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | | 主引用文献 | Structural basis for the interaction of the Golgi-Associated Retrograde Protein Complex with the t-SNARE Syntaxin 6.
Structure, 21, 2013
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8AFZ
 | | Architecture of the ESCPE-1 membrane coat | | 分子名称: | Cation-independent mannose-6-phosphate receptor, Sorting nexin-1, Sorting nexin-5 | | 著者 | Lopez-Robles, C, Scaramuzza, S, Astorga-Simon, E, Ishida, M, Williamsom, C.D, Banos-Mateos, S, Gil-Carton, D, Romero, M, Vidaurrazaga, A, Fernandez-Recio, J, Rojas, A.L, Bonifacino, J.S, Castano-Diez, D, Hierro, A. | | 登録日 | 2022-07-18 | | 公開日 | 2023-06-21 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (10 Å) | | 主引用文献 | Architecture of the ESCPE-1 membrane coat.
Nat.Struct.Mol.Biol., 30, 2023
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8ABQ
 | | Structure of the SNX1-SNX5 complex, Pt derivative | | 分子名称: | PLATINUM (II) ION, Sorting nexin-1, Sorting nexin-5 | | 著者 | Lopez-Robles, C, Scaramuzza, S, Astorga-Simon, E.N, Banos-Mateos, S, Vidaurrazaga, A, Rojas, A.L, Castano, D, Hierro, A. | | 登録日 | 2022-07-04 | | 公開日 | 2023-06-21 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Architecture of the ESCPE-1 membrane coat.
Nat.Struct.Mol.Biol., 30, 2023
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4KYI
 | | Crystal structure of the phospholipase VipD from Legionella pneumophila in complex with the human GTPase Rab5 | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Lucas, M, Gaspar, A.H, Pallara, C, Rojas, A.L, Fernandez-Recio, J, Machner, M.P, Hierro, A. | | 登録日 | 2013-05-29 | | 公開日 | 2014-08-13 | | 最終更新日 | 2015-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.075 Å) | | 主引用文献 | Structural basis for the recruitment and activation of the Legionella phospholipase VipD by the host GTPase Rab5.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4IIK
 | | Legionella pneumophila effector | | 分子名称: | Adenosine monophosphate-protein hydrolase SidD, CHLORIDE ION, GLYCEROL, ... | | 著者 | Tascon, I, Chen, Y, Neunuebel, M.R, Rojas, A.L, Machner, M.P, Hierro, A. | | 登録日 | 2012-12-20 | | 公開日 | 2013-06-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural Basis for Rab1 De-AMPylation by the Legionella pneumophila Effector SidD
Plos Pathog., 9, 2013
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4IIP
 | | Legionella pneumophila effector | | 分子名称: | Adenosine monophosphate-protein hydrolase SidD, CHLORIDE ION, GLYCEROL | | 著者 | Tascon, I, Chen, Y, Neunuebel, M.R, Rojas, A.L, Machner, M.P, Hierro, A. | | 登録日 | 2012-12-20 | | 公開日 | 2013-06-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Basis for Rab1 De-AMPylation by the Legionella pneumophila Effector SidD
Plos Pathog., 9, 2013
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5F0K
 | | Structure of VPS35 N terminal region | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, SULFATE ION, ... | | 著者 | Lucas, M, Gershlick, D, Vidaurrazaga, A, Rojas, A.L, Bonifacino, J.S, Hierro, A. | | 登録日 | 2015-11-27 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.074 Å) | | 主引用文献 | Structural Mechanism for Cargo Recognition by the Retromer Complex.
Cell, 167, 2016
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5F0M
 | | Structure of retromer VPS26-VPS35 subunits bound to SNX3 and DMT1 (SeMet labeled) | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Natural resistance-associated macrophage protein 2, ... | | 著者 | Lucas, M, Gershlick, D, Vidaurrazaga, A, Rojas, A.L, Bonifacino, J.S, Hierro, A. | | 登録日 | 2015-11-27 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural Mechanism for Cargo Recognition by the Retromer Complex.
Cell, 167, 2016
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5F0P
 | | Structure of retromer VPS26-VPS35 subunits bound to SNX3 and DMT1(L557M) (SeMet labeled) | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Natural resistance-associated macrophage protein 2, ... | | 著者 | Lucas, M, Gershlick, D, Vidaurrazaga, A, Rojas, A.L, Bonifacino, J.S, Hierro, A. | | 登録日 | 2015-11-27 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | | 主引用文献 | Structural Mechanism for Cargo Recognition by the Retromer Complex.
Cell, 167, 2016
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5F0J
 | | Structure of retromer VPS26-VPS35 subunits bound to SNX3 | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, SULFATE ION, ... | | 著者 | Lucas, M, Gershlick, D, Vidaurrazaga, A, Rojas, A.L, Bonifacino, J.S, Hierro, A. | | 登録日 | 2015-11-27 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural Mechanism for Cargo Recognition by the Retromer Complex.
Cell, 167, 2016
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5F0L
 | | Structure of retromer VPS26-VPS35 subunits bound to SNX3 and DMT1 | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Natural resistance-associated macrophage protein 2, ... | | 著者 | Lucas, M, Gershlick, D, Vidaurrazaga, A, Rojas, A.L, Bonifacino, J.S, Hierro, A. | | 登録日 | 2015-11-27 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural Mechanism for Cargo Recognition by the Retromer Complex.
Cell, 167, 2016
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