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PDB: 1 results

6E53
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BU of 6e53 by Molmil
Structure of TERT in complex with a novel telomerase inhibitor
Descriptor: MAGNESIUM ION, RNA/DNA hairpin, Telomerase reverse transcriptase, ...
Authors:Hernandez-Sanchez, W, Huang, W, Plucinsky, B, Garcia-Vazquez, N, Berdis, A.J, Skordalakes, E, Taylor, D.J.
Deposit date:2018-07-19
Release date:2019-03-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A non-natural nucleotide uses a specific pocket to selectively inhibit telomerase activity.
Plos Biol., 17, 2019

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