5T3K
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2OE6
| 2.4A X-ray crystal structure of unliganded RNA fragment GGGCGUCGCUAGUACC/CGGUACUAAAAGUCGCC containing the human ribosomal decoding A site: RNA construct with 5'-overhang | Descriptor: | RNA (5'-R(*CP*GP*GP*UP*AP*CP*UP*AP*AP*AP*AP*GP*UP*CP*GP*CP*C)-3'), RNA (5'-R(*GP*GP*GP*CP*GP*UP*CP*GP*CP*UP*AP*GP*UP*AP*CP*C)-3') | Authors: | Hermann, T, Tereshko, V, Skripkin, E, Patel, D.J. | Deposit date: | 2006-12-28 | Release date: | 2007-02-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Apramycin recognition by the human ribosomal decoding site. Blood Cells Mol.Dis., 38, 2007
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2OE8
| 1.8 A X-ray crystal structure of Apramycin complex with RNA fragment GGGCGUCGCUAGUACC/CGGUACUAAAAGUCGCC containing the human ribosomal decoding A site: RNA construct with 5'-overhang | Descriptor: | APRAMYCIN, RNA (5'-R(*CP*GP*GP*UP*AP*CP*UP*AP*AP*AP*AP*GP*UP*CP*GP*CP*C)-3'), RNA (5'-R(*GP*GP*GP*CP*GP*UP*CP*GP*CP*UP*AP*GP*UP*AP*CP*C)-3') | Authors: | Hermann, T, Tereshko, V, Skripkin, E, Patel, D.J. | Deposit date: | 2006-12-28 | Release date: | 2007-02-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Apramycin recognition by the human ribosomal decoding site. Blood Cells Mol.Dis., 38, 2007
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2OE5
| 1.5 A X-ray crystal structure of Apramycin complex with RNA fragment GGCGUCGCUAGUACCG/GGUACUAAAAGUCGCCC containing the human ribosomal decoding A site: RNA construct with 3'-overhang | Descriptor: | APRAMYCIN, MAGNESIUM ION, RNA (5'-R(*GP*GP*CP*GP*UP*CP*GP*CP*UP*AP*GP*UP*AP*CP*CP*G)-3'), ... | Authors: | Hermann, T, Tereshko, V, Skripkin, E, Patel, D.J. | Deposit date: | 2006-12-28 | Release date: | 2007-02-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Apramycin recognition by the human ribosomal decoding site. Blood Cells Mol.Dis., 38, 2007
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1EEG
| A(GGGG)A HEXAD PAIRING ALIGMENT FOR THE D(G-G-A-G-G-A-G) SEQUENCE | Descriptor: | DNA (5'-D(*GP*GP*AP*GP*GP*A)-3') | Authors: | Kettani, A, Gorin, A, Majumdar, A, Hermann, T, Skripkin, E, Zhao, H, Jones, R, Patel, D.J. | Deposit date: | 2000-01-31 | Release date: | 2000-04-02 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | A dimeric DNA interface stabilized by stacked A.(G.G.G.G).A hexads and coordinated monovalent cations. J.Mol.Biol., 297, 2000
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3P59
| First Crystal Structure of a RNA Nanosquare | Descriptor: | COBALT HEXAMMINE(III), MAGNESIUM ION, RNA (5'-R(*CP*CP*GP*GP*AP*GP*GP*AP*AP*CP*UP*AP*CP*(5BU)P*G)-3'), ... | Authors: | Dibrov, S, Hermann, T, McLean, J, Parsons, J. | Deposit date: | 2010-10-08 | Release date: | 2011-04-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1793 Å) | Cite: | Self-assembling RNA square. Proc.Natl.Acad.Sci.USA, 108, 2011
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4P97
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4PHY
| Functional conservation despite structural divergence in ligand-responsive RNA switches | Descriptor: | ACETATE ION, MAGNESIUM ION, RNA (26-MER), ... | Authors: | Boerneke, M.A, Dibrov, S.M, Hermann, T.H. | Deposit date: | 2014-05-07 | Release date: | 2015-02-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Functional conservation despite structural divergence in ligand-responsive RNA switches. Proc.Natl.Acad.Sci.USA, 111, 2014
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3MEI
| Regulatory motif from the thymidylate synthase mRNA | Descriptor: | MAGNESIUM ION, RNA (5'-R(*CP*CP*GP*CP*CP*GP*CP*GP*CP*CP*AP*(5BU)P*GP*CP*CP*UP*GP*UP*GP*GP*CP*GP*G)-3') | Authors: | Dibrov, S, McLean, J, Hermann, T. | Deposit date: | 2010-03-31 | Release date: | 2011-01-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.968 Å) | Cite: | Structure of an RNA dimer of a regulatory element from human thymidylate synthase mRNA. Acta Crystallogr.,Sect.D, 67, 2011
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5CNR
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1G70
| COMPLEX OF HIV-1 RRE-IIB RNA WITH RSG-1.2 PEPTIDE | Descriptor: | HIV-1 RRE-IIB 32 NUCLEOTIDE RNA, RSG-1.2 PEPTIDE | Authors: | Gosser, Y, Hermann, T, Majumdar, A, Hu, W, Frederick, R, Jiang, F, Xu, W, Patel, D.J. | Deposit date: | 2000-11-08 | Release date: | 2001-02-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Peptide-triggered conformational switch in HIV-1 RRE RNA complexes. Nat.Struct.Biol., 8, 2001
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3TZR
| Structure of a Riboswitch-like RNA-ligand complex from the Hepatitis C Virus Internal Ribosome Entry Site | Descriptor: | (8R)-8-[(dimethylamino)methyl]-1-[3-(dimethylamino)propyl]-1,7,8,9-tetrahydrochromeno[5,6-d]imidazol-2-amine, 5'-R(*CP*GP*AP*GP*GP*AP*AP*CP*UP*AP*CP*UP*GP*UP*CP*UP*UP*CP*CP*C)-3', 5'-R(*GP*GP*UP*CP*GP*UP*GP*CP*AP*GP*CP*CP*UP*CP*GP*G)-3', ... | Authors: | Dibrov, S.M, Ding, K, Brunn, N, Parker, M.A, Bergdahl, B.M, Wyles, D.L, Hermann, T. | Deposit date: | 2011-09-27 | Release date: | 2012-03-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.212 Å) | Cite: | Structure of a Riboswitch in the Hepatitis C Virus Internal Ribosome Entry Site To be Published
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2PN3
| Crystal Structure of Hepatitis C Virus IRES Subdomain IIa | Descriptor: | 5'-R(*CP*GP*GP*AP*GP*GP*AP*AP*CP*UP*AP*CP*UP*GP*UP*CP*UP*UP*CP*AP*CP*GP*CP*C)-3', 5'-R(*GP*CP*GP*(5BU)P*GP*UP*CP*GP*UP*GP*CP*AP*GP*CP*CP*(5BU)P*CP*CP*GP*G)-3', MAGNESIUM ION | Authors: | Zhao, Q, Han, Q, Kissinger, C.R, Hermann, T, Thompson, P.A. | Deposit date: | 2007-04-23 | Release date: | 2008-04-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of hepatitis C virus IRES subdomain IIa. Acta Crystallogr.,Sect.D, 64, 2008
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1T0D
| Crystal Structure of 2-aminopurine labelled bacterial decoding site RNA | Descriptor: | 5'-R(*CP*AP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*AP*CP*CP*C)-3', 5'-R(*GP*GP*UP*GP*GP*UP*GP*(MTU)P*AP*GP*UP*CP*GP*CP*UP*GP*G)-3' | Authors: | Shandrick, S, Zhao, Q, Han, Q, Ayida, B.K, Takahashi, M, Winters, G.C, Simonsen, K.B, Vourloumis, D, Hermann, T. | Deposit date: | 2004-04-08 | Release date: | 2004-06-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Monitoring molecular recognition of the ribosomal decoding site. Angew.Chem.Int.Ed.Engl., 43, 2004
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1T0E
| Crystal Structure of 2-aminopurine labelled bacterial decoding site RNA | Descriptor: | 5'-R(*CP*GP*AP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*AP*CP*CP*C)-3', 5'-R(*GP*GP*UP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*CP*UP*CP*GP*G)-3', SULFATE ION | Authors: | Shandrick, S, Zhao, Q, Han, Q, Ayida, B.K, Takahashi, M, Winters, G.C, Simonsen, K.B, Vourloumis, D, Hermann, T. | Deposit date: | 2004-04-08 | Release date: | 2004-06-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Monitoring molecular recognition of the ribosomal decoding site. Angew.Chem.Int.Ed.Engl., 43, 2004
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4GYH
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4H1I
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1YRJ
| Crystal Structure of Apramycin bound to a Ribosomal RNA A site oligonucleotide | Descriptor: | APRAMYCIN, Bacterial 16 S Ribosomal RNA A Site Oligonucleotide, MAGNESIUM ION, ... | Authors: | Han, Q, Zhao, Q, Fish, S, Simonsen, K.B, Vourloumis, D, Froelich, J.M, Wall, D, Hermann, T. | Deposit date: | 2005-02-03 | Release date: | 2005-06-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular recognition by glycoside pseudo base pairs and triples in an apramycin-RNA complex. Angew.Chem.Int.Ed.Engl., 44, 2005
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2A04
| Molecular Recognition of RNA by Neomycin and a Restricted Neomycin Derivative | Descriptor: | 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*AP*CP*C)-3', 5'-R(*GP*UP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*CP*GP*G)-3', MAGNESIUM ION, ... | Authors: | Zhao, Q, Zhao, F, Blount, K.F, Han, Q, Tor, Y, Hermann, T. | Deposit date: | 2005-06-15 | Release date: | 2005-09-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Molecular recognition of RNA by neomycin and a restricted neomycin derivative Angew.Chem.Int.Ed.Engl., 44, 2005
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1ZX7
| Molecular Recognition of RNA by Neomycin and a Restricted Neomycin Derivative | Descriptor: | 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*AP*CP*C)-3', 5'-R(*GP*UP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*CP*GP*G)-3' | Authors: | Zhao, Q, Zhao, F, Blount, K.F, Han, Q, Tor, Y, Hermann, T. | Deposit date: | 2005-06-07 | Release date: | 2005-09-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Molecular recognition of RNA by neomycin and a restricted neomycin derivative Angew.Chem.Int.Ed.Engl., 44, 2005
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1ZZ5
| Molecular Recognition of RNA by Neomycin and a Restricted Neomycin Derivative | Descriptor: | 13,15-DIAMINO-2-(AMINOMETHYL)-3,4,9,12-TETRAHYDROXYHEXADECAHYDRO-2H-7,10-EPOXYPYRANO[2,3-B][1,10,4]BENZODIOXAZACYCLODODECIN-8-YL 2,6-DIAMINO-2,6-DIDEOXYHEXOPYRANOSIDE, 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*AP*CP*C)-3', 5'-R(*GP*UP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*CP*GP*G)-3', ... | Authors: | Zhao, Q, Zhao, F, Blount, K.F, Han, Q, Tor, Y, Hermann, T. | Deposit date: | 2005-06-13 | Release date: | 2005-09-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Molecular recognition of RNA by neomycin and a restricted neomycin derivative Angew.Chem.Int.Ed.Engl., 44, 2005
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8ADD
| Viral tegument-like DUBs | Descriptor: | ATP-dependent DNA helicase | Authors: | Erven, I, Abraham, E.T, Hermanns, T, Hofmann, K, Baumann, U. | Deposit date: | 2022-07-08 | Release date: | 2023-02-15 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A widely distributed family of eukaryotic and bacterial deubiquitinases related to herpesviral large tegument proteins. Nat Commun, 13, 2022
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8CMR
| Linear specific OTU-type DUB SnOTU from the pathogen S. negenvensis in complex with linear di-ubiquitin | Descriptor: | OTU domain-containing protein, Polyubiquitin-B | Authors: | Uthoff, M, Hermanns, T, Boll, V, Hofmann, K, Baumann, U. | Deposit date: | 2023-02-21 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Functional and structural diversity in deubiquitinases of the Chlamydia-like bacterium Simkania negevensis. Nat Commun, 14, 2023
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7OJE
| Crystal structure of the covalent complex between Tribolium castaneum deubiquitinase ZUP and Ubiquitin-PA | Descriptor: | 1,2-ETHANEDIOL, CITRIC ACID, Lys-63-specific deubiquitinase ZUFSP, ... | Authors: | Pichlo, C, Hermanns, T, Hofmann, K, Baumann, U. | Deposit date: | 2021-05-14 | Release date: | 2022-02-02 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | A structural basis for the diverse linkage specificities within the ZUFSP deubiquitinase family. Nat Commun, 13, 2022
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7OIY
| Crystal structure of the ZUFSP family member Mug105 | Descriptor: | SODIUM ION, Ubiquitin carboxyl-terminal hydrolase mug105 | Authors: | Pichlo, C, Hermanns, T, Hofmann, K, Baumann, U. | Deposit date: | 2021-05-12 | Release date: | 2022-02-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | A structural basis for the diverse linkage specificities within the ZUFSP deubiquitinase family. Nat Commun, 13, 2022
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