1GEC
| GLYCYL ENDOPEPTIDASE-COMPLEX WITH BENZYLOXYCARBONYL-LEUCINE-VALINE-GLYCINE-METHYLENE COVALENTLY BOUND TO CYSTEINE 25 | Descriptor: | BENZYLOXYCARBONYL-LEUCINE-VALINE-GLYCINE-METHYLENE INHIBITOR, GLYCYL ENDOPEPTIDASE | Authors: | Ohara, B.P, Hemmings, A.M, Buttle, D.J, Pearl, L.H. | Deposit date: | 1995-05-25 | Release date: | 1995-12-07 | Last modified: | 2012-12-12 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of glycyl endopeptidase from Carica papaya: a cysteine endopeptidase of unusual substrate specificity. Biochemistry, 34, 1995
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9EQK
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9EQH
| WWP2 WW2-2,3-linker-HECT (WWP2-LH) | Descriptor: | GLYCEROL, Isoform 2 of NEDD4-like E3 ubiquitin-protein ligase WWP2, SODIUM ION | Authors: | Dudey, A.P, Hemmings, A.M. | Deposit date: | 2024-03-21 | Release date: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Expanding the Inhibitor Space of the WWP1 and WWP2 HECT E3 Ligases To Be Published
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8OXE
| Inositol 1,3,4-trisphosphate 5/6-kinase 1 from Solanum tuberosum (StITPK1) in complex with ADP/Mg2+ | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Inositol-tetrakisphosphate 1-kinase, MAGNESIUM ION | Authors: | Faba-Rodriguez, R, Li, A.W.H, Brearley, C.A, Hemmings, A.M. | Deposit date: | 2023-05-02 | Release date: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 ( St ITPK1). Biochemistry, 63, 2024
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7R5Y
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4NG0
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7PUP
| INOSITOL 1,3,4-TRISPHOSPHATE 5/6-KINASE 4 from Arabidopsis thaliana (AtITPK4) in complex with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Inositol 1,3,4-trisphosphate 5/6-kinase 4 | Authors: | Whitfield, H, He, S, Brearley, C.A, Hemmings, A.M. | Deposit date: | 2021-09-30 | Release date: | 2022-10-12 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Diversification in the inositol tris/tetrakisphosphate kinase (ITPK) family: crystal structure and enzymology of the outlier AtITPK4. Biochem.J., 480, 2023
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5FD6
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3TOR
| Crystal structure of Escherichia coli NrfA with Europium bound | Descriptor: | CALCIUM ION, Cytochrome c nitrite reductase, EUROPIUM ION, ... | Authors: | Lockwood, C.W.J, Clarke, T.A, Butt, J.N, Hemmings, A.M, Richardson, D.J. | Deposit date: | 2011-09-06 | Release date: | 2011-12-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Characterization of the active site and calcium binding in cytochrome c nitrite reductases. Biochem.Soc.Trans., 39, 2011
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5CU7
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5CX4
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4MT5
| Crystal structure of Mub-RV | Descriptor: | Mucus binding proteinn | Authors: | Etzold, S, Juge, N, Hemmings, A.M. | Deposit date: | 2013-09-19 | Release date: | 2014-08-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for adaptation of lactobacilli to gastrointestinal mucus. ENVIRON.MICROBIOL., 16, 2014
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3L1T
| E. coli NrfA sulfite ocmplex | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Cytochrome c-552, ... | Authors: | Clarke, T.A, Hemmings, A.M, Butt, J.N. | Deposit date: | 2009-12-14 | Release date: | 2010-10-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Kinetic and thermodynamic resolution of the interactions between sulfite and the pentahaem cytochrome NrfA from Escherichia coli Biochem.J., 431, 2010
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3PHV
| X-RAY ANALYSIS OF HIV-1 PROTEINASE AT 2.7 ANGSTROMS RESOLUTION CONFIRMS STRUCTURAL HOMOLOGY AMONG RETROVIRAL ENZYMES | Descriptor: | UNLIGANDED HIV-1 PROTEASE | Authors: | Lapatto, R, Blundell, T.L, Hemmings, A, Wilderspin, A, Wood, S.P, Danley, D.E, Geoghegan, K.F, Hawrylik, S.J, Hobart, P.M. | Deposit date: | 1991-11-04 | Release date: | 1992-01-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | X-ray analysis of HIV-1 proteinase at 2.7 A resolution confirms structural homology among retroviral enzymes. Nature, 342, 1989
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4XKT
| E coli BFR variant Y149F | Descriptor: | Bacterioferritin, SULFATE ION | Authors: | Bradley, J.M, Hemmings, A.M, Le Brun, N.E. | Deposit date: | 2015-01-12 | Release date: | 2015-12-16 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Three Aromatic Residues are Required for Electron Transfer during Iron Mineralization in Bacterioferritin. Angew.Chem.Int.Ed.Engl., 54, 2015
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3I9Z
| Crystal structure of a metallochaperone with a trinuclear Cu(I) cluster | Descriptor: | COPPER (I) ION, Copper chaperone copZ | Authors: | Hearnshaw, S.J, Zhou, L, Le Brun, N.E, Hemmings, A.M. | Deposit date: | 2009-07-13 | Release date: | 2009-11-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mechanistic insights into Cu(I) cluster transfer between the chaperone CopZ and its cognate Cu(I)-transporting P-type ATPase, CopA. Biochem.J., 424, 2009
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7ZGF
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7Z3V
| Escherichia coli periplasmic phytase AppA D304E mutant, complex with myo-inositol hexakissulfate | Descriptor: | Acidphosphatase, D-MYO-INOSITOL-HEXASULPHATE, POTASSIUM ION | Authors: | Acquistapace, I.M, Brearley, C.A, Hemmings, A.M. | Deposit date: | 2022-03-02 | Release date: | 2022-06-29 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA. Int J Mol Sci, 23, 2022
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7Z2Y
| Escherichia coli periplasmic phytase AppA T305E mutant, complex with myo-inositol hexakissulfate | Descriptor: | Acidphosphatase, D-MYO-INOSITOL-HEXASULPHATE, NICKEL (II) ION | Authors: | Acquistapace, I.M, Brearley, C.A, Hemmings, A.M. | Deposit date: | 2022-03-01 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA. Int J Mol Sci, 23, 2022
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7Z2W
| Escherichia coli periplasmic phytase AppA D304A,T305E mutant, complex with myo-inositol hexakissulfate | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acidphosphatase, D-MYO-INOSITOL-HEXASULPHATE, ... | Authors: | Acquistapace, I.M, Brearley, C.A, Hemmings, A.M. | Deposit date: | 2022-03-01 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA. Int J Mol Sci, 23, 2022
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7Z1J
| Escherichia coli periplasmic phytase AppA, complex with phosphate | Descriptor: | Acidphosphatase, MAGNESIUM ION, NICKEL (II) ION, ... | Authors: | Acquistapace, I.M, Brearley, C.A, Hemmings, A.M. | Deposit date: | 2022-02-24 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA. Int J Mol Sci, 23, 2022
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7Z2S
| Escherichia coli periplasmic phytase AppA, complex with myo-inositol hexakissulfate | Descriptor: | Acidphosphatase, D-MYO-INOSITOL-HEXASULPHATE, NICKEL (II) ION, ... | Authors: | Acquistapace, I.M, Brearley, C.A, Hemmings, A.M. | Deposit date: | 2022-02-28 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA. Int J Mol Sci, 23, 2022
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7Z32
| Escherichia coli periplasmic phytase AppA D304A mutant, phosphohistidine intermediate | Descriptor: | Acidphosphatase, NICKEL (II) ION | Authors: | Acquistapace, I.M, Brearley, C.A, Hemmings, A.M. | Deposit date: | 2022-03-01 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA. Int J Mol Sci, 23, 2022
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7Z2T
| Escherichia coli periplasmic phytase AppA D304A mutant, complex with myo-inositol hexakissulfate | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acidphosphatase, D-MYO-INOSITOL-HEXASULPHATE, ... | Authors: | Acquistapace, I.M, Brearley, C.A, Hemmings, A.M. | Deposit date: | 2022-02-28 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA. Int J Mol Sci, 23, 2022
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1QO8
| The structure of the open conformation of a flavocytochrome c3 fumarate reductase | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, FLAVOCYTOCHROME C3 FUMARATE REDUCTASE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Bamford, V, Dobbin, P.S, Richardson, D.J, Hemmings, A.M. | Deposit date: | 1999-11-04 | Release date: | 2000-11-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Open Conformation of a Flavocytochrome C3 Fumarate Reductase. Nat.Struct.Biol., 6, 1999
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