2YKT
 
 | | Crystal structure of the I-BAR domain of IRSp53 (BAIAP2) in complex with an EHEC derived Tir peptide | | Descriptor: | BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2, SULFATE ION, TRANSLOCATED INTIMIN RECEPTOR PROTEIN | | Authors: | de Groot, J.C, Schlueter, K, Carius, Y, Quedenau, C, Vingadassalom, D, Faix, J, Weiss, S.M, Reichelt, J, Standfuss-Gabisch, C, Lesser, C.F, Leong, J.M, Heinz, D.W, Buessow, K, Stradal, T.E.B. | | Deposit date: | 2011-05-30 | | Release date: | 2011-09-07 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | Structural Basis for Complex Formation between Human Irsp53 and the Translocated Intimin Receptor Tir of Enterohemorrhagic E. Coli.
Structure, 19, 2011
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2WQV
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2W0R
 | | Crystal structure of the mutated N263D YscU C-terminal domain | | Descriptor: | CHLORIDE ION, YSCU | | Authors: | Wiesand, U, Sorg, I, Amstutz, M, Wagner, S, Van Den Heuvel, J, Luehrs, T, Cornelis, G.R, Heinz, D.W. | | Deposit date: | 2008-10-06 | | Release date: | 2008-11-04 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structure of the Type III Secretion Recognition Protein Yscu from Yersinia Enterocolitica
J.Mol.Biol., 385, 2009
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2YBQ
 | | The x-ray structure of the SAM-dependent uroporphyrinogen III methyltransferase NirE from Pseudomonas aeruginosa in complex with SAH and uroporphyrinogen III | | Descriptor: | METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE, UROPORPHYRINOGEN III | | Authors: | Storbeck, S, Saha, S, Krausze, J, Klink, B.U, Heinz, D.W, Layer, G. | | Deposit date: | 2011-03-09 | | Release date: | 2011-06-01 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of the Heme D1 Biosynthesis Enzyme Nire in Complex with its Substrate Reveals New Insights Into the Catalytic Mechanism of S-Adenosyl-L-Methionine-Dependent Uroporphyrinogen III Methyltransferases.
J.Biol.Chem., 286, 2011
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2YBO
 | | The x-ray structure of the SAM-dependent uroporphyrinogen III methyltransferase NirE from Pseudomonas aeruginosa in complex with SAH | | Descriptor: | METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Storbeck, S, Saha, S, Krausze, J, Klink, B.U, Heinz, D.W, Layer, G. | | Deposit date: | 2011-03-08 | | Release date: | 2011-06-01 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of the Heme D1 Biosynthesis Enzyme Nire in Complex with its Substrate Reveals New Insights Into the Catalytic Mechanism of S-Adenosyl-L-Methionine-Dependent Uroporphyrinogen III Methyltransferases.
J.Biol.Chem., 286, 2011
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4A1X
 | | Co-Complex structure of NS3-4A protease with the inhibitory peptide CP5-46-A (Synchrotron data) | | Descriptor: | CHLORIDE ION, CP5-46-A PEPTIDE, NONSTRUCTURAL PROTEIN 4A, ... | | Authors: | Schmelz, S, Kuegler, J, Collins, J, Heinz, D. | | Deposit date: | 2011-09-20 | | Release date: | 2012-09-19 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | High Affinity Peptide Inhibitors of the Hepatitis C Virus Ns3-4A Protease Refractory to Common Resistant Mutants.
J.Biol.Chem., 287, 2012
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4AIK
 | | Crystal structure of RovA from Yersinia in complex with an invasin promoter fragment | | Descriptor: | ROVA PROMOTER FRAGMENT, 5'-D(*AP*TP*GP*AP*TP*AP*TP*TP *AP*TP**TP*TP*AP*TP*AP*TP*GP*AP*TP*AP*A)-3', 5'-D(*TP*TP*TP*AP*TP*CP*AP*TP *AP*TP*AP*AP*AP*TP*AP*AP*TP*AP*TP*CP*A)-3', ... | | Authors: | Quade, N, Mendonca, C, Herbst, K, Heroven, A.K, Heinz, D.W, Dersch, P. | | Deposit date: | 2012-02-10 | | Release date: | 2012-09-12 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural Basis for Intrinsic Thermosensing by the Master Virulence Regulator Rova of Yersinia.
J.Biol.Chem., 287, 2012
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5AGU
 | | The sliding clamp of Mycobacterium tuberculosis in complex with a natural product. | | Descriptor: | (R,R)-2,3-BUTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA POLYMERASE III SUBUNIT BETA, ... | | Authors: | Lukat, P, Kling, A, Heinz, D.W, Mueller, R. | | Deposit date: | 2015-02-03 | | Release date: | 2015-06-03 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.173 Å) | | Cite: | Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins.
Science, 348, 2015
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4AIJ
 | | Crystal structure of RovA from Yersinia in complex with a rovA promoter fragment | | Descriptor: | ROVA PROMOTER FRAGMENT, 5'-D(*AP*AP*TP*TP*AP*TP*AP*TP *TP*AP*TP*TP*TP*GP*AP*AP*TP*TP*AP*AP*T)-3', 5'-D(*TP*AP*TP*TP*AP*AP*TP*TP *CP*AP*AP*AP*TP*AP*AP*TP*AP*TP*AP*AP*T)-3', ... | | Authors: | Quade, N, Mendonca, C, Herbst, K, Heroven, A.K, Heinz, D.W, Dersch, P. | | Deposit date: | 2012-02-10 | | Release date: | 2012-09-12 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural Basis for Intrinsic Thermosensing by the Master Virulence Regulator Rova of Yersinia.
J.Biol.Chem., 287, 2012
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5AGV
 | | The sliding clamp of Mycobacterium tuberculosis in complex with a natural product. | | Descriptor: | (R,R)-2,3-BUTANEDIOL, CALCIUM ION, CYCLOHEXYL GRISELIMYCIN, ... | | Authors: | Lukat, P, Kling, A, Heinz, D.W, Mueller, R. | | Deposit date: | 2015-02-03 | | Release date: | 2015-06-03 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins.
Science, 348, 2015
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5AH4
 | | The sliding clamp of Mycobacterium smegmatis in complex with a natural product. | | Descriptor: | CYCLOHEXYL GRISELIMYCIN, DNA POLYMERASE III SUBUNIT BETA, SODIUM ION | | Authors: | Lukat, P, Kling, A, Heinz, D.W, Mueller, R. | | Deposit date: | 2015-02-04 | | Release date: | 2015-06-03 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.313 Å) | | Cite: | Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins.
Science, 348, 2015
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5AH2
 | | The sliding clamp of Mycobacterium smegmatis in complex with a natural product. | | Descriptor: | DNA POLYMERASE III SUBUNIT BETA, GRISELIMYCIN, SODIUM ION | | Authors: | Lukat, P, Kling, A, Heinz, D.W, Mueller, R. | | Deposit date: | 2015-02-04 | | Release date: | 2015-06-03 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.129 Å) | | Cite: | Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins.
Science, 348, 2015
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4D3Z
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4D3X
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4D3Y
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1B4K
 | | High resolution crystal structure of a MG2-dependent 5-aminolevulinic acid dehydratase | | Descriptor: | LAEVULINIC ACID, MAGNESIUM ION, PROTEIN (5-AMINOLEVULINIC ACID DEHYDRATASE), ... | | Authors: | Frankenberg, N, Jahn, D, Heinz, D.W. | | Deposit date: | 1998-12-22 | | Release date: | 1999-07-13 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | High resolution crystal structure of a Mg2+-dependent porphobilinogen synthase.
J.Mol.Biol., 289, 1999
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4AOQ
 | | Cationic trypsin in complex with mutated Spinacia oleracea trypsin inhibitor III (SOTI-III) (F14A) | | Descriptor: | CALCIUM ION, CATIONIC TRYPSIN, PENTAETHYLENE GLYCOL, ... | | Authors: | Schmelz, S, Glotzbach, B, Reinwarth, M, Christmann, A, Kolmar, H, Heinz, D.W. | | Deposit date: | 2012-03-29 | | Release date: | 2013-01-09 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Characterization of Spinacia Oleracea Trypsin Inhibitor III (Soti-III)
Acta Crystallogr.,Sect.D, 69, 2013
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4AOR
 | | Cationic trypsin in complex with the Spinacia oleracea trypsin inhibitor III (SOTI-III) | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CATIONIC TRYPSIN, ... | | Authors: | Schmelz, S, Glotzbach, B, Reinwarth, M, Christmann, A, Kolmar, H, Heinz, D.W. | | Deposit date: | 2012-03-29 | | Release date: | 2013-01-09 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.702 Å) | | Cite: | Structural Characterization of Spinacia Oleracea Trypsin Inhibitor III (Soti-III)
Acta Crystallogr.,Sect.D, 69, 2013
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4ALZ
 | | The Yersinia T3SS basal body component YscD reveals a different structural periplasmatic domain organization to known homologue PrgH | | Descriptor: | GLYCEROL, PHOSPHATE ION, YOP PROTEINS TRANSLOCATION PROTEIN D | | Authors: | Schmelz, S, Wisand, U, Stenta, M, Muenich, S, Widow, U, Cornelis, G.R, Heinz, D.W. | | Deposit date: | 2012-03-06 | | Release date: | 2013-04-24 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | In Situ Structural Analysis of the Yersinia Enterocolitica Injectisome.
Elife, 2, 2013
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4ABI
 | | Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (PtA)SFTI-1(1,14), that was 1,4-disubstituted with a 1,2,3- trizol to mimic a trans amide bond | | Descriptor: | CALCIUM ION, CATIONIC TRYPSIN, DIMETHYLFORMAMIDE, ... | | Authors: | Schmelz, S, Empting, M, Tischler, M, Nasu, D, Heinz, D, Kolmar, H. | | Deposit date: | 2011-12-08 | | Release date: | 2012-03-07 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Braces for the Peptide Backbone: Insights Into Structure-Activity Relation-Ships of Protease Inhibitor Mimics with Locked Amide Conformations
Angew.Chem.Int.Ed.Engl., 51, 2012
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4ABJ
 | | Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (IcA)SFTI-1(1,14), that was 1,5-disubstituted with 1,2,3- trizol to mimic a cis amide bond | | Descriptor: | CALCIUM ION, CATIONIC TRYPSIN, DIMETHYLFORMAMIDE, ... | | Authors: | Schmelz, S, Empting, M, Tischler, M, Nasu, D, Heinz, D, Kolmar, H. | | Deposit date: | 2011-12-08 | | Release date: | 2012-03-07 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Braces for the Peptide Backbone: Insights Into Structure-Activity Relation-Ships of Protease Inhibitor Mimics with Locked Amide Conformations
Angew.Chem.Int.Ed.Engl., 51, 2012
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4B0F
 | | Heptameric core complex structure of C4b-binding (C4BP) protein from human | | Descriptor: | C4B-BINDING PROTEIN ALPHA CHAIN, CHLORIDE ION | | Authors: | Schmelz, S, Hofmeyer, T, Kolmar, H, Heinz, D.W. | | Deposit date: | 2012-07-02 | | Release date: | 2013-01-09 | | Last modified: | 2017-07-12 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Arranged Sevenfold: Structural Insights Into the C-Terminal Oligomerization Domain of Human C4B-Binding Protein.
J.Mol.Biol., 425, 2013
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4A0S
 | | STRUCTURE OF THE 2-OCTENOYL-COA CARBOXYLASE REDUCTASE CINF IN COMPLEX WITH NADP AND 2-OCTENOYL-COA | | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, OCTANOYL-COENZYME A, OCTENOYL-COA REDUCTASE/CARBOXYLASE | | Authors: | Quade, N, Huo, L, Rachid, S, Heinz, D.W, Muller, R. | | Deposit date: | 2011-09-12 | | Release date: | 2011-12-07 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Unusual carbon fixation gives rise to diverse polyketide extender units.
Nat. Chem. Biol., 8, 2011
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4AIH
 | | Crystal structure of RovA from Yersinia in its free form | | Descriptor: | TRANSCRIPTIONAL REGULATOR SLYA | | Authors: | Quade, N, Mendonca, C, Herbst, K, Heroven, A.K, Heinz, D.W, Dersch, P. | | Deposit date: | 2012-02-09 | | Release date: | 2012-09-12 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural Basis for Intrinsic Thermosensing by the Master Virulence Regulator Rova of Yersinia.
J.Biol.Chem., 287, 2012
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1O6S
 | | Internalin (Listeria monocytogenes) / E-Cadherin (human) Recognition Complex | | Descriptor: | CALCIUM ION, CHLORIDE ION, E-CADHERIN, ... | | Authors: | Schubert, W.-D, Urbanke, C, Ziehm, T, Beier, V, Machner, M.P, Domann, E, Wehland, J, Chakraborty, T, Heinz, D.W. | | Deposit date: | 2002-10-13 | | Release date: | 2002-12-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of Internalin, a Major Invasion Protein of Listeria Monocytogenes, in Complex with its Human Receptor E-Cadherin
Cell(Cambridge,Mass.), 111, 2002
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