5Z05
| Crystal structure of signalling protein from buffalo (SPB-40) with an acetone induced conformation of Trp78 at 1.49 A resolution | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETONE, ... | 著者 | Singh, P.K, Chaudhary, A, Tyagi, T.K, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2017-12-18 | 公開日 | 2018-01-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | A glycoprotein from mammary gland secreted during involution promotes apoptosis: Structural and biological studies Arch. Biochem. Biophys., 644, 2018
|
|
1LND
| A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN | 分子名称: | CALCIUM ION, DIMETHYL SULFOXIDE, LYSINE, ... | 著者 | Holland, D.R, Hausrath, A.C, Juers, D, Matthews, B.W. | 登録日 | 1994-05-13 | 公開日 | 1995-05-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural analysis of zinc substitutions in the active site of thermolysin. Protein Sci., 4, 1995
|
|
8A8J
| Complex of RecF and DNA from Thermus thermophilus. | 分子名称: | DNA replication and repair protein RecF, MAGNESIUM ION, Oligo1, ... | 著者 | Nirwal, S, Czarnocki-Cieciura, M, Chaudhary, A, Zajko, W, Skowronek, K, Chamera, S, Figiel, M, Nowotny, M. | 登録日 | 2022-06-23 | 公開日 | 2023-04-26 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Mechanism of RecF-RecO-RecR cooperation in bacterial homologous recombination. Nat.Struct.Mol.Biol., 30, 2023
|
|
8A93
| Complex of RecF-RecR-DNA from Thermus thermophilus. | 分子名称: | DNA replication and repair protein RecF, MAGNESIUM ION, Oligo1, ... | 著者 | Nirwal, S, Czarnocki-Cieciura, M, Chaudhary, A, Zajko, W, Skowronek, K, Chamera, S, Figiel, M, Nowotny, M. | 登録日 | 2022-06-27 | 公開日 | 2023-04-26 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Mechanism of RecF-RecO-RecR cooperation in bacterial homologous recombination. Nat.Struct.Mol.Biol., 30, 2023
|
|
8BPR
| Complex of RecF-RecO-RecR-DNA from Thermus thermophilus (low resolution reconstruction). | 分子名称: | DNA repair protein RecO, DNA replication and repair protein RecF, MAGNESIUM ION, ... | 著者 | Nirwal, S, Czarnocki-Cieciura, M, Chaudhary, A, Zajko, W, Skowronek, K, Chamera, S, Figiel, M, Nowotny, M. | 登録日 | 2022-11-17 | 公開日 | 2023-04-26 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | Mechanism of RecF-RecO-RecR cooperation in bacterial homologous recombination. Nat.Struct.Mol.Biol., 30, 2023
|
|
6IX6
| Crystal structure of the complex of peptidyl-tRNA hydrolase with N-propanol at 1.43 A resolution | 分子名称: | N-PROPANOL, Peptidyl-tRNA hydrolase | 著者 | Viswanathan, V, Sharma, P, Chaudhary, A, Sharma, S, Singh, T.P. | 登録日 | 2018-12-09 | 公開日 | 2018-12-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Crystal structure of the complex of peptidyl-tRNA hydrolase with N-propanol at 1.43 A resolution To Be Published
|
|
4U7W
| The crystal structure of the terminal R domain from the myxalamid PKS-NRPS biosynthetic pathway | 分子名称: | ACETATE ION, MxaA, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Tsai, S.C, Keasling, J.D, Luo, R, Barajas, J.F, Phelan, R.M, Schaub, A.J, Kliewer, J. | 登録日 | 2014-07-31 | 公開日 | 2015-08-12 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.899 Å) | 主引用文献 | Comprehensive Structural and Biochemical Analysis of the Terminal Myxalamid Reductase Domain for the Engineered Production of Primary Alcohols. Chem.Biol., 22, 2015
|
|
5GUY
| Structural and functional study of chuY from E. coli CFT073 strain | 分子名称: | Uncharacterized protein chuY | 著者 | Kim, H, Choi, J, HA, S.C, Chaurasia, A.K, Kim, D, Kim, K.K. | 登録日 | 2016-08-31 | 公開日 | 2017-03-08 | 実験手法 | X-RAY DIFFRACTION (2.399 Å) | 主引用文献 | Structural and functional study of ChuY from Escherichia coli strain CFT073 Biochem. Biophys. Res. Commun., 482, 2017
|
|
8AB0
| Complex of RecO-RecR-DNA from Thermus thermophilus. | 分子名称: | DNA repair protein RecO, Oligo1, Oligo2, ... | 著者 | Nirwal, S, Czarnocki-Cieciura, M, Chaudhary, A, Zajko, W, Skowronek, K, Chamera, S, Figiel, M, Nowotny, M. | 登録日 | 2022-07-04 | 公開日 | 2023-04-26 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (6.09 Å) | 主引用文献 | Mechanism of RecF-RecO-RecR cooperation in bacterial homologous recombination. Nat.Struct.Mol.Biol., 30, 2023
|
|
6FFC
| Structure of an inhibitor-bound ABC transporter | 分子名称: | ATP-binding cassette sub-family G member 2, ~{tert}-butyl 3-[(2~{S},5~{S},8~{S})-14-cyclopentyloxy-2-(2-methylpropyl)-4,7-bis(oxidanylidene)-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1(10),11,13,15-tetraen-5-yl]propanoate | 著者 | Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Taylor, N.M.I, Bause, M, Bauer, S, Bartholomaeus, R, Stahlberg, H, Bernhardt, G, Koenig, B, Buschauer, A, Altmann, K.H, Locher, K.P. | 登録日 | 2018-01-06 | 公開日 | 2018-04-11 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.56 Å) | 主引用文献 | Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. Nat. Struct. Mol. Biol., 25, 2018
|
|
3MNQ
| Crystal structure of myosin-2 motor domain in complex with ADP-metavanadate and resveratrol | 分子名称: | 1,2-ETHANEDIOL, ADP METAVANADATE, MAGNESIUM ION, ... | 著者 | Schneider, J, Taft, M, Backhaus, A, Baruch, P, Fedorov, R, Manstein, D.J. | 登録日 | 2010-04-22 | 公開日 | 2011-04-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis of resveratrol regulation of myosin activity. To be Published
|
|
6IYE
| |
1U8T
| Crystal structure of CheY D13K Y106W alone and in complex with a FliM peptide | 分子名称: | Chemotaxis protein cheY, Flagellar motor switch protein fliM, SULFATE ION | 著者 | Dyer, C.M, Quillin, M.L, Campos, A, Lu, J, McEvoy, M.M, Hausrath, A.C, Westbrook, E.M, Matsumura, P, Matthews, B.W, Dahlquist, F.W. | 登録日 | 2004-08-06 | 公開日 | 2004-10-05 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure of the Constitutively Active Double Mutant CheY(D13K Y106W) Alone and in Complex with a FliM Peptide J.Mol.Biol., 342, 2004
|
|
4MAV
| Crystal structure of signaling protein SPB-40 complexed with 5-hydroxymethyl oxalanetriol at 2.80 A resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase-3-like protein 1, GLYCEROL, ... | 著者 | Yamini, S, Chaudhary, A, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2013-08-17 | 公開日 | 2013-09-11 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Crystal structure of signaling protein SPB-40 complexed with 5-hydroxymethyl oxalanetriol at 2.80 A resolution To be Published
|
|
3TU3
| 1.92 Angstrom resolution crystal structure of the full-length SpcU in complex with full-length ExoU from the type III secretion system of Pseudomonas aeruginosa | 分子名称: | ExoU, ExoU chaperone | 著者 | Halavaty, A.S, Borek, D, Otwinowski, Z, Minasov, G, Veesenmeyer, J.L, Tyson, G, Shuvalova, L, Hauser, A.R, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2011-09-15 | 公開日 | 2012-05-23 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structure of the Type III Secretion Effector Protein ExoU in Complex with Its Chaperone SpcU. Plos One, 7, 2012
|
|
3SNL
| Highly Potent, Selective, and Orally Active Phosphodiestarase 10A Inhibitors | 分子名称: | 6-chloro-3,4-dimethyl-1-(3-methylpyridin-4-yl)-8-(trifluoromethyl)imidazo[1,5-a]quinoxaline, MAGNESIUM ION, ZINC ION, ... | 著者 | Malamas, M.S, Ni, Y, Erdei, J, Stange, H, Schindler, R, Lankau, H.-J, Grunwald, C, Fan, K.Y, Parris, K.D, Langen, B, Egerland, U, Hage, T, Marquis, K.L, Grauer, S, Brennan, J, Navarra, R, Graf, R, Harrison, B.L, Robichaud, A, Kronbach, T, Pangalos, M, Hofgen, N, Brandon, N.J. | 登録日 | 2011-06-29 | 公開日 | 2011-10-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Highly Potent, Selective, and Orally Active Phosphodiesterase 10A Inhibitors. J.Med.Chem., 54, 2011
|
|
4B7M
| H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | van der Vries, E, Vachieri, S.G, Xiong, X, Liu, J, Collins, P.J, Walker, P.A, Haire, L.F, Hay, A.J, Schutten, M, Osterhaus, A.D.M.E, Martin, S.R, Boucher, C.A.B, Skehel, J.J, Gamblin, S.J. | 登録日 | 2012-08-21 | 公開日 | 2012-10-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis Plos Pathog., 8, 2012
|
|
4B7N
| H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NEURAMINIDASE, ... | 著者 | van der Vries, E, Vachieri, S.G, Xiong, X, Liu, J, Collins, P.J, Walker, P.A, Haire, L.F, Hay, A.J, Schutten, M, Osterhaus, A.D.M.E, Martin, S.R, Boucher, C.A.B, Skehel, J.J, Gamblin, S.J. | 登録日 | 2012-08-21 | 公開日 | 2012-10-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis Plos Pathog., 8, 2012
|
|
4B7Q
| H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NEURAMINIDASE, ... | 著者 | Liu, J, van der Vries, E, Vachieri, S.G, Xiong, X, Collins, P.J, Walker, P.A, Haire, L.F, Hay, A.J, Schutten, M, Osterhaus, A.D.M.E, Martin, S.R, Boucher, C.A.B, Skehel, J.J, Gamblin, S.J. | 登録日 | 2012-08-21 | 公開日 | 2012-10-03 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.728 Å) | 主引用文献 | H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis Plos Pathog., 8, 2012
|
|
4B7R
| H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Liu, J, van der Vries, E, Vachieri, S.G, Xiong, X, Collins, P.J, Walker, P.A, Haire, L.F, Hay, A.J, Schutten, M, Osterhaus, A.D.M.E, Martin, S.R, Boucher, C.A.B, Skehel, J.J, Gamblin, S.J. | 登録日 | 2012-08-21 | 公開日 | 2012-10-03 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis Plos Pathog., 8, 2012
|
|
3SNI
| Highly Potent, Selective, and Orally Active Phosphodiestarase 10A Inhibitors | 分子名称: | 2-methoxy-6,7-dimethyl-9-(4-methylpyridin-3-yl)imidazo[1,5-a]pyrido[3,2-e]pyrazine, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Malamas, M.S, Ni, Y, Erdei, J, Stange, H, Schindler, R, Lankau, H.-J, Grunwald, C, Fan, K.Y, Parris, K.D, Langen, B, Egerland, U, Hage, T, Marquis, K.L, Grauer, S, Brennan, J, Navarra, R, Graf, R, Harrison, B.L, Robichaud, A, Kronbach, T, Pangalos, M, Hofgen, N, Brandon, N.J. | 登録日 | 2011-06-29 | 公開日 | 2011-10-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Highly Potent, Selective, and Orally Active Phosphodiesterase 10A Inhibitors. J.Med.Chem., 54, 2011
|
|
4B7J
| H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | van der Vries, E, Vachieri, S.G, Xiong, X, Liu, J, Collins, P.J, Walker, P.A, Haire, L.F, Hay, A.J, Schutten, M, Osterhaus, A.D.M.E, Martin, S.R, Boucher, C.A.B, Skehel, J.J, Gamblin, S.J. | 登録日 | 2012-08-20 | 公開日 | 2012-10-03 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.417 Å) | 主引用文献 | H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis Plos Pathog., 8, 2012
|
|
4CBT
| Design, synthesis, and biological evaluation of potent and selective Class IIa HDAC inhibitors as a potential therapy for Huntington's disease | 分子名称: | (1R,2R,3R)-2-[4-(5-fluoranylpyrimidin-2-yl)phenyl]-N-oxidanyl-3-phenyl-cyclopropane-1-carboxamide, HISTONE DEACETYLASE 4, ZINC ION | 著者 | Burli, R.W, Luckhurst, C.A, Aziz, O, Matthews, K.L, Yates, D, Lyons, K.A, Beconi, M, McAllister, G, Breccia, P, Stott, A.J, Penrose, S.D, Wall, M, Lamers, M, Leonard, P, Mueller, I, Richardson, C.M, Jarvis, R, Stones, L, Hughes, S, Wishart, G, Haughan, A.F, O'Connell, C, Mead, T, McNeil, H, Vann, J, Mangette, J, Maillard, M, Beaumont, V, Munoz-Sanjuan, I, Dominguez, C. | 登録日 | 2013-10-16 | 公開日 | 2013-12-11 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | 主引用文献 | Design, synthesis, and biological evaluation of potent and selective class IIa histone deacetylase (HDAC) inhibitors as a potential therapy for Huntington's disease. J. Med. Chem., 56, 2013
|
|
2XRY
| X-ray structure of archaeal class II CPD photolyase from Methanosarcina mazei | 分子名称: | DEOXYRIBODIPYRIMIDINE PHOTOLYASE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | 著者 | Kiontke, S, Geisselbrecht, Y, Pokorny, R, Carell, T, Batschauer, A, Essen, L.O. | 登録日 | 2010-09-24 | 公開日 | 2011-09-14 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal Structures of an Archaeal Class II DNA Photolyase and its Complex with Uv-Damaged Duplex DNA. Embo J., 30, 2011
|
|
2XRZ
| X-ray structure of archaeal class II CPD photolyase from Methanosarcina mazei in complex with intact CPD-lesion | 分子名称: | ACETATE ION, COUNTERSTRAND-OLIGONUCLEOTIDE, CPD-COMPRISING OLIGONUCLEOTIDE, ... | 著者 | Kiontke, S, Geisselbrecht, Y, Pokorny, R, Carell, T, Batschauer, A, Essen, L.O. | 登録日 | 2010-09-24 | 公開日 | 2011-09-14 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structures of an Archaeal Class II DNA Photolyase and its Complex with Uv-Damaged Duplex DNA. Embo J., 30, 2011
|
|