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PDB: 32 件
6H1F
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BU of 6h1f by Molmil
Structure of the nanobody-stabilized gelsolin D187N variant (second domain)
分子名称: Gelsolin, THIOCYANATE ION, gelsolin nanobody, ...
著者Hassan, A, Milani, M, Mastrangelo, E, de Rosa, M.
登録日2018-07-11
公開日2019-01-23
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Nanobody interaction unveils structure, dynamics and proteotoxicity of the Finnish-type amyloidogenic gelsolin variant.
Biochim Biophys Acta Mol Basis Dis, 1865, 2019
5IEI
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BU of 5iei by Molmil
X-ray crystallographic structure of a high affinity IGF2 antagonist (Domain11 AB5 RHH) based on human IGF2R domain 11
分子名称: 1,2-ETHANEDIOL, Cation-independent mannose-6-phosphate receptor, GLYCEROL, ...
著者Nicholls, R.D, Williams, C, Strickland, M, Frago, S, Hassan, A.B, Crump, M.P.
登録日2016-02-25
公開日2016-05-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist.
Proc.Natl.Acad.Sci.USA, 113, 2016
3S49
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BU of 3s49 by Molmil
RNA crystal structure with 2-Se-uridine modification
分子名称: POTASSIUM ION, RNA (5'-R(*GP*UP*AP*UP*AP*(RUS)P*AP*C)-3')
著者Sheng, J, Gan, J, Sun, H, Hassan, A.E.H, Jiang, S, Huang, Z.
登録日2011-05-19
公開日2011-06-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Higher Specificity of RNA Base Pairing with 2-Selenouridine
To be Published
1OTX
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BU of 1otx by Molmil
Purine Nucleoside Phosphorylase M64V mutant
分子名称: PHOSPHATE ION, Purine nucleoside phosphorylase
著者Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, W.B, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
登録日2003-03-23
公開日2004-02-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OV6
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BU of 1ov6 by Molmil
M64V PNP + ALLO
分子名称: 9-(6-DEOXY-BETA-D-ALLOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase
著者Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, P.W, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
登録日2003-03-25
公開日2004-02-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OVG
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BU of 1ovg by Molmil
M64V PNP +MePdr
分子名称: 9-(2-DEOXY-BETA-D-RIBOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase
著者Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, P.W, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
登録日2003-03-26
公開日2004-02-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OU4
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BU of 1ou4 by Molmil
Native PNP +Talo
分子名称: 6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase
著者Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, W.B, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
登録日2003-03-24
公開日2004-02-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OTY
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BU of 1oty by Molmil
Native PNP +ALLO
分子名称: 6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase
著者Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, W.B, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
登録日2003-03-23
公開日2004-02-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OUM
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BU of 1oum by Molmil
M64V PNP +Talo
分子名称: 9-(6-DEOXY-ALPHA-L-TALOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase
著者Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, W.B, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
登録日2003-03-24
公開日2004-02-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
3BM0
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BU of 3bm0 by Molmil
Structure of DNA Octamer G(dUSe)G(5-SedU)ACAC
分子名称: 5'-D(*GP*(2'-Se-U)P*GP*(5-Se-U)P*AP*CP*AP*C)-3'
著者Jiang, J, SHeng, J, Hassan, A.E, Huang, Z.
登録日2007-12-11
公開日2008-06-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Synthesis and crystallographic analysis of 5-Se-thymidine DNAs.
Org.Lett., 11, 2009
3LTR
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BU of 3ltr by Molmil
5-OMe-dU containing DNA 8mer
分子名称: 5'-D(*GP*(UMS)P*GP*(T5O)P*AP*CP*AP*C)-3', MAGNESIUM ION
著者Sheng, J, Hassan, A.E.A, Zhang, W, Gan, J, Huang, Z.
登録日2010-02-16
公開日2010-03-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Hydrogen bond formation between the naturally modified nucleobase and phosphate backbone.
Nucleic Acids Res., 40, 2012
3IKI
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BU of 3iki by Molmil
5-SMe-dU containing DNA octamer
分子名称: 5'-D(*GP*(UMS)P*GP*(US2)P*AP*CP*AP*C)-3', MAGNESIUM ION
著者Sheng, J, Hassan, A.E.A, Zhang, W, Gan, J, Huang, Z.
登録日2009-08-05
公開日2010-03-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Hydrogen bond formation between the naturally modified nucleobase and phosphate backbone.
Nucleic Acids Res., 40, 2012
2CNJ
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BU of 2cnj by Molmil
NMR studies on the interaction of Insulin-Growth Factor II (IGF-II) with IGF2R domain 11
分子名称: CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR
著者Williams, C, Prince, S, Zaccheo, O, Hassan, A.B, Crosby, J, Crump, M.
登録日2006-05-22
公開日2007-05-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Insights Into the Interaction of Insulin-Like Growth Factor 2 with Igf2R Domain 11.
Structure, 15, 2007
1GP0
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BU of 1gp0 by Molmil
Human IGF2R domain 11
分子名称: CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR, SULFATE ION
著者Brown, J, Esnouf, R.M, Jones, M.A, Linnell, J, Harlos, K, Hassan, A.B, Jones, E.Y.
登録日2001-10-29
公開日2002-02-28
最終更新日2019-04-10
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure of a Functional Igf2R Fragment Determined from the Anomalous Scattering of Sulfur
Embo J., 21, 2002
1GP3
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BU of 1gp3 by Molmil
Human IGF2R domain 11
分子名称: CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR
著者Brown, J, Esnouf, R.M, Jones, M.A, Linnell, J, Harlos, K, Hassan, A.B, Jones, E.Y.
登録日2001-10-29
公開日2002-02-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of a Functional Igf2R Fragment Determined from the Anomalous Scattering of Sulfur
Embo J., 21, 2002
2V5P
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BU of 2v5p by Molmil
COMPLEX STRUCTURE OF HUMAN IGF2R DOMAINS 11-13 BOUND TO IGF-II
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR, INSULIN-LIKE GROWTH FACTOR II, ...
著者Brown, J, Delaine, C, Zaccheo, O.J, Siebold, C, Gilbert, R.J, van Boxel, G, Denley, A, Wallace, J.C, Hassan, A.B, Forbes, B.E, Jones, E.Y.
登録日2007-07-06
公開日2007-12-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Structure and Functional Analysis of the Igf-II/Igf2R Interaction
Embo J., 27, 2008
2V5N
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BU of 2v5n by Molmil
STRUCTURE OF HUMAN IGF2R DOMAINS 11-12
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR
著者Brown, J, Delaine, C, Zaccheo, O.J, Siebold, C, Gilbert, R.J, van Boxel, G, Denley, A, Wallace, J.C, Hassan, A.B, Forbes, B.E, Jones, E.Y.
登録日2007-07-06
公開日2007-12-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure and Functional Analysis of the Igf-II/Igf2R Interaction
Embo J., 27, 2008
2V5O
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BU of 2v5o by Molmil
STRUCTURE OF HUMAN IGF2R DOMAINS 11-14
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR, CHLORIDE ION
著者Brown, J, Delaine, C, Zaccheo, O.J, Siebold, C, Gilbert, R.J, van Boxel, G, Denley, A, Wallace, J.C, Hassan, A.B, Forbes, B.E, Jones, E.Y.
登録日2007-07-06
公開日2007-12-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Structure and Functional Analysis of the Igf-II/Igf2R Interaction
Embo J., 27, 2008
3FA1
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BU of 3fa1 by Molmil
Crystal Structure of Tellurium Derivatized DNA
分子名称: 5'-D(*DGP*(UMS)P*DGP*(TTI)P*DAP*DCP*DAP*DC)-3'
著者Sheng, J, Tatsuya, M, Hassan, A.E, Huang, Z.
登録日2008-11-14
公開日2009-01-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure of Tellurium Derivatized DNA
To be Published
3HGD
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BU of 3hgd by Molmil
Crystal Structure of 2-Se-Thymidine Derivatized DNA
分子名称: 5'-D(*GP*(UMS)P*GP*(US3)P*AP*CP*AP*C)-3'
著者Sheng, J, Hassan, A.E, Zhang, W, Huang, Z.
登録日2009-05-13
公開日2009-08-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献High fidelity of base pairing by 2-selenothymidine in DNA.
J.Am.Chem.Soc., 132, 2010
3K18
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BU of 3k18 by Molmil
Tellurium modified DNA-8mer
分子名称: 5'-D(*GP*(UMS)P*GP*(TTI)P*AP*CP*AP*C)-3'
著者Sheng, J, Hassan, A.E.A, Zhang, W, Huang, Z.
登録日2009-09-25
公開日2010-10-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Synthesis and Structure Study of Oligonucleotides Derivatized with Tellurium Functionality
To be Published
3KQ8
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BU of 3kq8 by Molmil
5-Te-uridine derivatized DNA-8mer
分子名称: 5'-D(*GP*(UMS)P*GP*(TTI)P*AP*CP*AP*C)-3', MAGNESIUM ION
著者Sheng, J, Hassan, A.E.A, Zhang, W, Huang, Z.
登録日2009-11-17
公開日2010-11-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Synthesis and Structure studies of 5-Tellurium modified DNA
To be Published
3IJN
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BU of 3ijn by Molmil
5-SeMe-Cytidine modified DNA 8mer
分子名称: 5'-D(*GP*(UMS)P*GP*TP*AP*(5SE)P*AP*C)-3'
著者Sheng, J, Zhang, W, Hassan, A.E.A, Gan, J, Huang, Z.
登録日2009-08-04
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献5-SeMe-Cytidine modified DNA 8mer
TO BE PUBLISHED
2LLA
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BU of 2lla by Molmil
NMR solution structure ensemble of domain 11 of the echidna M6P/IGF2R receptor
分子名称: Mannose-6-phosphate/insulin-like growth factor II receptor
著者Strickland, M, Crump, M.P, Williams, C, Rezgui, D, Ellis, R.Z, Hoppe, H, Frago, S, Prince, S.N, Zaccheo, O.J, Forbes, B.E, Jones, E, Hassan, A.Z, Wattana-Amorn, P.
登録日2011-11-05
公開日2012-11-07
最終更新日2012-12-12
実験手法SOLUTION NMR
主引用文献An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.
Science, 338, 2012
2L29
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BU of 2l29 by Molmil
Complex structure of E4 mutant human IGF2R domain 11 bound to IGF-II
分子名称: Insulin-like growth factor 2 receptor variant, Insulin-like growth factor II
著者Williams, C, Hoppe, H, Rezgui, D, Strickland, M, Frago, S, Ellis, R.Z, Wattana-Amorn, P, Prince, S.N, Zaccheo, O.J, Forbes, B, Jones, E.Y, Crump, M.P, Hassan, A.B.
登録日2010-08-13
公開日2012-02-15
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.
Science, 338, 2012

 

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