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PDB: 2 results

5UVG
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BU of 5uvg by Molmil
Crystal structure of the human neutral sphingomyelinase 2 (nSMase2) catalytic domain with insertion deleted and calcium bound
Descriptor: CALCIUM ION, Sphingomyelin phosphodiesterase 3,Sphingomyelin phosphodiesterase 3
Authors:Airola, M.V, Guja, K.E, Garcia-Diaz, M, Hannun, Y.A.
Deposit date:2017-02-20
Release date:2017-06-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.849 Å)
Cite:Structure of human nSMase2 reveals an interdomain allosteric activation mechanism for ceramide generation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4WGK
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BU of 4wgk by Molmil
Crystal structure of human neutral ceramidase with Zn-bound phosphate
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Airola, M.V, Pulkoski-Gross, M.J, Obeid, L.M, Hannun, Y.A.
Deposit date:2014-09-18
Release date:2015-07-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.582 Å)
Cite:Structural Basis for Ceramide Recognition and Hydrolysis by Human Neutral Ceramidase.
Structure, 23, 2015

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