8YN7
 
 | | Cryo-EM structure of histamine H3 receptor in complex with immethridine and miniGo | | 分子名称: | 4-(1H-imidazol-4-ylmethyl)pyridine, Antibody fragment scFv16, CHOLESTEROL, ... | | 著者 | Zhang, X, Liu, G, Li, X, Gong, W. | | 登録日 | 2024-03-10 | | 公開日 | 2024-10-16 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | Structural basis of ligand recognition and activation of the histamine receptor family.
Nat Commun, 15, 2024
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8YN2
 | | Cryo-EM structure of histamine H1 receptor in complex with histamine and miniGq | | 分子名称: | Antibody fragment scFv16, CHOLESTEROL, Engineered guanine nucleotide-binding protein G(q) subunit alpha, ... | | 著者 | Zhang, X, Liu, G, Li, X, Gong, W. | | 登録日 | 2024-03-10 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | | 主引用文献 | Structural basis of ligand recognition and activation of the histamine receptor family.
Nat Commun, 15, 2024
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8YN9
 | | Cryo-EM structure of histamine H4 receptor in complex with histamine and Gi | | 分子名称: | Antibody fragment scFv16, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Zhang, X, Liu, G, Li, X, Gong, W. | | 登録日 | 2024-03-10 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Structural basis of ligand recognition and activation of the histamine receptor family.
Nat Commun, 15, 2024
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8YN5
 | | Cryo-EM structure of histamine H3 receptor in complex with histamine and Gi | | 分子名称: | Antibody fragment scFv16, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Zhang, X, Liu, G, Li, X, Gong, W. | | 登録日 | 2024-03-10 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural basis of ligand recognition and activation of the histamine receptor family.
Nat Commun, 15, 2024
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8YN4
 | | Cryo-EM structure of histamine H2 receptor in complex with histamine and miniGq | | 分子名称: | Antibody fragment scFv16, CHOLESTEROL, Engineered guanine nucleotide-binding protein G(q) subunit alpha, ... | | 著者 | Zhang, X, Liu, G, Li, X, Gong, W. | | 登録日 | 2024-03-10 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | | 主引用文献 | Structural basis of ligand recognition and activation of the histamine receptor family.
Nat Commun, 15, 2024
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8YN3
 | | Cryo-EM structure of histamine H2 receptor in complex with histamine and miniGs | | 分子名称: | CHOLESTEROL, Engineered guanine nucleotide,binding protein G(s) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Zhang, X, Liu, G, Li, X, Gong, W. | | 登録日 | 2024-03-10 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.56 Å) | | 主引用文献 | Structural basis of ligand recognition and activation of the histamine receptor family.
Nat Commun, 15, 2024
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8YNA
 | | Cryo-EM structure of histamine H4 receptor in complex with immepip and Gi | | 分子名称: | 4-(1H-imidazol-5-ylmethyl)piperidine, Antibody fragment scFv16, CHOLESTEROL, ... | | 著者 | Zhang, X, Liu, G, Li, X, Gong, W. | | 登録日 | 2024-03-10 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.63 Å) | | 主引用文献 | Structural basis of ligand recognition and activation of the histamine receptor family.
Nat Commun, 15, 2024
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8YN6
 | | Cryo-EM structure of histamine H3 receptor in complex with imetit and Gi | | 分子名称: | 2-(1~{H}-imidazol-5-yl)ethyl carbamimidothioate, Antibody fragment scFv16, CHOLESTEROL, ... | | 著者 | Zhang, X, Liu, G, Li, X, Gong, W. | | 登録日 | 2024-03-10 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | Structural basis of ligand recognition and activation of the histamine receptor family.
Nat Commun, 15, 2024
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7X1Z
 | | Structure of the phosphorylation-site double mutant S431E/T432E of the KaiC circadian clock protein | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Circadian clock oscillator protein KaiC, MAGNESIUM ION | | 著者 | Han, X, Zhang, D.L, Hong, L, Yu, D.Q, Wu, Z.L, Yang, T, Rust, M.J, Tu, Y.H, Ouyang, Q. | | 登録日 | 2022-02-25 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-11-08 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Determining subunit-subunit interaction from statistics of cryo-EM images: observation of nearest-neighbor coupling in a circadian clock protein complex
Nat Commun, 14, 2023
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7X1Y
 | | Structure of the phosphorylation-site double mutant S431A/T432A of the KaiC circadian clock protein | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Circadian clock oscillator protein KaiC, MAGNESIUM ION | | 著者 | Han, X, Zhang, D.L, Hong, L, Yu, D.Q, Wu, Z.L, Yang, T, Rust, M.J, Tu, Y.H, Ouyang, Q. | | 登録日 | 2022-02-25 | | 公開日 | 2023-04-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Determining subunit-subunit interaction from statistics of cryo-EM images: observation of nearest-neighbor coupling in a circadian clock protein complex
Nat Commun, 14, 2023
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4MH1
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4LSW
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8YN8
 | | Cryo-EM structure of histamine H3 receptor in complex with proxyfan and miniGo | | 分子名称: | 5-(3-phenylmethoxypropyl)-1H-imidazole, Antibody fragment scFv16, CHOLESTEROL, ... | | 著者 | Zhang, X, Liu, G, Li, X, Gong, W. | | 登録日 | 2024-03-10 | | 公開日 | 2024-10-16 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | Structural basis of ligand recognition and activation of the histamine receptor family.
Nat Commun, 15, 2024
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3JB7
 | | In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus | | 分子名称: | CPV RNA-dependent RNA polymerase, CYTIDINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Zhang, X, Ding, K, Yu, X.K, Chang, W, Sun, J.C, Zhou, Z.H. | | 登録日 | 2015-08-03 | | 公開日 | 2015-10-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus.
Nature, 527, 2015
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5V56
 | | 2.9A XFEL structure of the multi-domain human smoothened receptor (with E194M mutation) in complex with TC114 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN MONONUCLEOTIDE, N-methyl-N-[1-[4-(2-methylpyrazol-3-yl)phthalazin-1-yl]piperidin-4-yl]-4-nitro-2-(trifluoromethyl)benzamide, ... | | 著者 | Zhang, X, Zhao, F, Wu, Y, Yang, J, Han, G.W, Zhao, S, Ishchenko, A, Ye, L, Lin, X, Ding, K, Dharmarajan, V, Griffin, P.R, Gati, C, Nelson, G, Hunter, M.S, Hanson, M.A, Cherezov, V, Stevens, R.C, Tan, W, Tao, H, Xu, F. | | 登録日 | 2017-03-13 | | 公開日 | 2017-05-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand.
Nat Commun, 8, 2017
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5V57
 | | 3.0A SYN structure of the multi-domain human smoothened receptor in complex with TC114 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, FLAVIN MONONUCLEOTIDE, N-methyl-N-[1-[4-(2-methylpyrazol-3-yl)phthalazin-1-yl]piperidin-4-yl]-4-nitro-2-(trifluoromethyl)benzamide, ... | | 著者 | Zhang, X, Zhao, F, Wu, Y, Yang, J, Han, G.W, Zhao, S, Ishchenko, A, Ye, L, Lin, X, Ding, K, Dharmarajan, V, Griffin, P.R, Gati, C, Nelson, G, Hunter, M.S, Hanson, M.A, Cherezov, V, Stevens, R.C, Tan, W, Tao, H, Xu, F. | | 登録日 | 2017-03-13 | | 公開日 | 2017-05-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand.
Nat Commun, 8, 2017
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3KLX
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4QQR
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8C0B
 | | CryoEM structure of Aspergillus nidulans UTP-glucose-1-phosphate uridylyltransferase | | 分子名称: | UTP--glucose-1-phosphate uridylyltransferase | | 著者 | Han, X, D Angelo, C, Otamendi, A, Cifuente, J.O, de Astigarraga, E, Ochoa-Lizarralde, B, Grininger, M, Routier, F.H, Guerin, M.E, Fuehring, J, Etxebeste, O, Connell, S.R. | | 登録日 | 2022-12-16 | | 公開日 | 2023-06-28 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.98 Å) | | 主引用文献 | CryoEM analysis of the essential native UDP-glucose pyrophosphorylase from Aspergillus nidulans reveals key conformations for activity regulation and function.
Mbio, 14, 2023
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7XGD
 | | Cryo-EM structure of Apo-IGF1R map 1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor 1 receptor | | 著者 | Zhang, X, Wu, C. | | 登録日 | 2022-04-04 | | 公開日 | 2023-04-12 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Cryo-EM structure of Apo-IGF1R
To Be Published
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5DQE
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5DQ8
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8GZD
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7YKP
 | | Crystal structure of a novel alpha/beta hydrolase from thermomonospora curvata with glycerol | | 分子名称: | GLYCEROL, Triacylglycerol lipase | | 著者 | Han, X, Jian, G, Bornscheuer, U.T, Wei, R, Liu, W. | | 登録日 | 2022-07-23 | | 公開日 | 2023-07-26 | | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | | 主引用文献 | Crystal structure of a novel alpha/beta hydrolase from thermomonospora curvata with glycerol
To Be Published
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7YKO
 | | Crystal structure of a novel alpha/beta hydrolase mutant from thermomonospora curvata in complex with pentane-1,5-diol | | 分子名称: | Triacylglycerol lipase, pentane-1,5-diol | | 著者 | Han, X, Jian, G, Bornscheuer, U.T, Wei, R, Liu, W. | | 登録日 | 2022-07-23 | | 公開日 | 2023-07-26 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Crystal structure of a novel alpha/beta hydrolase mutant from thermomonospora curvata in complex with pentane-1,5-diol
To Be Published
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