4HCQ
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![BU of 4hcq by Molmil](/molmil-images/mine/4hcq) | Crystal structure of GLMU from mycobacterium tuberculosis in complex with glucosamine-1-phosphate | Descriptor: | 2-acetamido-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, Bifunctional protein GlmU, COBALT (II) ION, ... | Authors: | Jagtap, P.K.A, Verma, S.K, Vithani, N. | Deposit date: | 2012-10-01 | Release date: | 2013-03-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structures identify an atypical two-metal-ion mechanism for uridyltransfer in GlmU: its significance to sugar nucleotidyl transferases J.Mol.Biol., 425, 2013
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2Z0F
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2Y8C
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![BU of 2y8c by Molmil](/molmil-images/mine/2y8c) | Plasmodium falciparum dUTPase in complex with a trityl ligand | Descriptor: | (2S)-2-[(2,4-dioxopyrimidin-1-yl)methyl]-N-(2-hydroxyethyl)-4-trityloxy-butanamide, DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE, SULFATE ION | Authors: | Baragana, B, McCarthy, O, Sanchez, P, Bosch, C, Kaiser, M, Brun, R, Whittingham, J.L, Roberts, S, Zhou, X.-X, Wilson, K.S, Johansson, N.G, Gonzalez-Pacanowska, D, Gilbert, I.H. | Deposit date: | 2011-02-04 | Release date: | 2012-03-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Beta-Branched Acyclic Nucleoside Analogues as Inhibitors of Plasmodium Falciparum Dutpase Bioorg.Med.Chem., 19, 2011
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3QX3
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![BU of 3qx3 by Molmil](/molmil-images/mine/3qx3) | Human topoisomerase IIbeta in complex with DNA and etoposide | Descriptor: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), ... | Authors: | Wu, C.C, Li, T.K, Farh, L, Lin, L.Y, Lin, T.S, Yu, Y.J, Yen, T.J, Chiang, C.W, Chan, N.L. | Deposit date: | 2011-03-01 | Release date: | 2011-07-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.162 Å) | Cite: | Structural basis of type II topoisomerase inhibition by the anticancer drug etoposide Science, 333, 2011
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3T60
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![BU of 3t60 by Molmil](/molmil-images/mine/3t60) | 5'-Diphenyl Nucleoside Inhibitors of Plasmodium falciparum dUTPase | Descriptor: | 2',5'-dideoxy-5'-(tritylamino)uridine, Deoxyuridine 5'-triphosphate nucleotidohydrolase, putative, ... | Authors: | Hampton, S.E, Baragana, B, Schipani, A, Bosch-Navarrete, C, Musso-Buendia, A, Recio, E, Kaiser, M, Whittingham, J.L, Roberts, S.M, Shevtsov, M, Brannigan, J.A, Kahnberg, P, Brun, R, Wilson, K.S, Gonzalez-Pacanowska, D, Johansson, N.G, Gilbert, I.H. | Deposit date: | 2011-07-28 | Release date: | 2012-08-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.396 Å) | Cite: | Design, synthesis, and evaluation of 5'-diphenyl nucleoside analogues as inhibitors of the Plasmodium falciparum dUTPase. Chemmedchem, 6, 2011
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3W9Y
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![BU of 3w9y by Molmil](/molmil-images/mine/3w9y) | Crystal structure of the human DLG1 guanylate kinase domain | Descriptor: | Disks large homolog 1 | Authors: | Mori, S, Tezuka, Y, Arakawa, A, Handa, N, Shirouzu, M, Akiyama, T, Yokoyama, S. | Deposit date: | 2013-04-18 | Release date: | 2013-06-26 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the guanylate kinase domain from discs large homolog 1 (DLG1/SAP97) Biochem.Biophys.Res.Commun., 435, 2013
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3T64
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![BU of 3t64 by Molmil](/molmil-images/mine/3t64) | 5'-Diphenyl Nucleoside Inhibitors of Plasmodium falciparum dUTPase | Descriptor: | 2',5'-dideoxy-5'-[(diphenylmethyl)amino]uridine, 5'-(BENZHYDRYLAMINO)-2',5'-DIDEOXYURIDINE, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... | Authors: | Hampton, S.E, Baragana, B, Schipani, A, Bosch-Navarrete, C, Musso-Buendia, A, Recio, E, Kaiser, M, Whittingham, J.L, Roberts, S.M, Shevtsov, M, Brannigan, J.A, Kahnberg, P, Brun, R, Wilson, K.S, Gonzalez-Pacanowska, D, Johansson, N.G, Gilbert, I.H. | Deposit date: | 2011-07-28 | Release date: | 2012-08-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Design, synthesis, and evaluation of 5'-diphenyl nucleoside analogues as inhibitors of the Plasmodium falciparum dUTPase. Chemmedchem, 6, 2011
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1FPZ
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![BU of 1fpz by Molmil](/molmil-images/mine/1fpz) | CRYSTAL STRUCTURE ANALYSIS OF KINASE ASSOCIATED PHOSPHATASE (KAP) WITH A SUBSTITUTION OF THE CATALYTIC SITE CYSTEINE (CYS140) TO A SERINE | Descriptor: | CYCLIN-DEPENDENT KINASE INHIBITOR 3, SULFATE ION | Authors: | Song, H, Hanlon, N, Brown, N.R, Noble, M.E.M, Johnson, L.N, Barford, D. | Deposit date: | 2000-09-01 | Release date: | 2001-05-09 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2. Mol.Cell, 7, 2001
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2ZRA
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![BU of 2zra by Molmil](/molmil-images/mine/2zra) | MsRecA Q196E ATPgS | Descriptor: | CHLORIDE ION, GLYCEROL, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Prabu, J.R, Manjunath, G.P, Chandra, N.R, Muniyappa, K, Vijayan, M. | Deposit date: | 2008-08-27 | Release date: | 2008-12-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Functionally important movements in RecA molecules and filaments: studies involving mutation and environmental changes Acta Crystallogr.,Sect.D, 64, 2008
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2ZRG
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![BU of 2zrg by Molmil](/molmil-images/mine/2zrg) | MsRecA Q196N dATP form II' | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Protein recA | Authors: | Prabu, J.R, Manjunath, G.P, Chandra, N.R, Muniyappa, K, Vijayan, M. | Deposit date: | 2008-08-27 | Release date: | 2008-12-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Functionally important movements in RecA molecules and filaments: studies involving mutation and environmental changes Acta Crystallogr.,Sect.D, 64, 2008
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2ZRP
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![BU of 2zrp by Molmil](/molmil-images/mine/2zrp) | MsRecA dATP form II' | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Protein recA | Authors: | Prabu, J.R, Manjunath, G.P, Chandra, N.R, Muniyappa, K, Vijayan, M. | Deposit date: | 2008-08-27 | Release date: | 2008-12-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Functionally important movements in RecA molecules and filaments: studies involving mutation and environmental changes Acta Crystallogr.,Sect.D, 64, 2008
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2ZR9
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![BU of 2zr9 by Molmil](/molmil-images/mine/2zr9) | MsRecA Q196E dATP form IV | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | Authors: | Prabu, J.R, Manjunath, G.P, Chandra, N.R, Muniyappa, K, Vijayan, M. | Deposit date: | 2008-08-27 | Release date: | 2008-12-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Functionally important movements in RecA molecules and filaments: studies involving mutation and environmental changes Acta Crystallogr.,Sect.D, 64, 2008
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2ZRH
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![BU of 2zrh by Molmil](/molmil-images/mine/2zrh) | MsRecA Q196A form IV | Descriptor: | PHOSPHATE ION, Protein recA | Authors: | Prabu, J.R, Manjunath, G.P, Chandra, N.R, Muniyappa, K, Vijayan, M. | Deposit date: | 2008-08-27 | Release date: | 2008-12-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Functionally important movements in RecA molecules and filaments: studies involving mutation and environmental changes Acta Crystallogr.,Sect.D, 64, 2008
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2ZR7
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![BU of 2zr7 by Molmil](/molmil-images/mine/2zr7) | Msreca native form II' | Descriptor: | PHOSPHATE ION, Protein recA | Authors: | Prabu, J.R, Manjunath, G.P, Chandra, N.R, Muniyappa, K, Vijayan, M. | Deposit date: | 2008-08-25 | Release date: | 2008-12-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Functionally important movements in RecA molecules and filaments: studies involving mutation and environmental changes Acta Crystallogr.,Sect.D, 64, 2008
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2ZRF
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![BU of 2zrf by Molmil](/molmil-images/mine/2zrf) | MsRecA Q196N dATP form IV | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Protein recA | Authors: | Prabu, J.R, Manjunath, G.P, Chandra, N.R, Muniyappa, K, Vijayan, M. | Deposit date: | 2008-08-27 | Release date: | 2008-12-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Functionally important movements in RecA molecules and filaments: studies involving mutation and environmental changes Acta Crystallogr.,Sect.D, 64, 2008
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2ZRN
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![BU of 2zrn by Molmil](/molmil-images/mine/2zrn) | MsRecA Form IV | Descriptor: | GLYCEROL, PHOSPHATE ION, Protein recA | Authors: | Prabu, J.R, Manjunath, G.P, Chandra, N.R, Muniyappa, K, Vijayan, M. | Deposit date: | 2008-08-27 | Release date: | 2008-12-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Functionally important movements in RecA molecules and filaments: studies involving mutation and environmental changes Acta Crystallogr.,Sect.D, 64, 2008
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3AY9
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![BU of 3ay9 by Molmil](/molmil-images/mine/3ay9) | Crystal structure of human Hsp70 NBD in the ADP-, Mg ion-, and K ion-bound state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, CHLORIDE ION, ... | Authors: | Arakawa, A, Handa, N, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2011-05-03 | Release date: | 2011-12-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Biochemical and structural studies on the high affinity of Hsp70 for ADP. Protein Sci., 20, 2011
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3B6H
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![BU of 3b6h by Molmil](/molmil-images/mine/3b6h) | Crystal structure of human prostacyclin synthase in complex with inhibitor minoxidil | Descriptor: | 6-PIPERIDIN-1-YLPYRIMIDINE-2,4-DIAMINE 3-OXIDE, PROTOPORPHYRIN IX CONTAINING FE, Prostacyclin synthase, ... | Authors: | Li, Y.-C, Chiang, C.-W, Yeh, H.-C, Hsu, P.-Y, Whitby, F.G, Wang, L.-H, Chan, N.-L. | Deposit date: | 2007-10-29 | Release date: | 2007-11-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Structures of Prostacyclin Synthase and Its Complexes with Substrate Analog and Inhibitor Reveal a Ligand-specific Heme Conformation Change J.Biol.Chem., 283, 2008
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3B99
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![BU of 3b99 by Molmil](/molmil-images/mine/3b99) | Crystal structure of zebrafish prostacyclin synthase (cytochrome P450 8A1) in complex with substrate analog U51605 | Descriptor: | (5Z)-7-{(1R,4S,5R,6R)-6-[(1E)-oct-1-en-1-yl]-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl}hept-5-enoic acid, PROTOPORPHYRIN IX CONTAINING FE, Prostaglandin I2 synthase | Authors: | Li, Y.-C, Chiang, C.-W, Yeh, H.-C, Hsu, P.-Y, Whitby, F.G, Wang, L.-H, Chan, N.-L. | Deposit date: | 2007-11-03 | Release date: | 2007-11-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of Prostacyclin Synthase and Its Complexes with Substrate Analog and Inhibitor Reveal a Ligand-specific Heme Conformation Change J.Biol.Chem., 283, 2008
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7DO1
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![BU of 7do1 by Molmil](/molmil-images/mine/7do1) | |
3ATV
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![BU of 3atv by Molmil](/molmil-images/mine/3atv) | Crystal structure of human Hsp70 NBD in the ADP-bound and Mg ion-free state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Heat shock 70 kDa protein 1A/1B, ... | Authors: | Arakawa, A, Handa, N, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2011-01-13 | Release date: | 2011-12-28 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Biochemical and structural studies on the high affinity of Hsp70 for ADP. Protein Sci., 20, 2011
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3ATU
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![BU of 3atu by Molmil](/molmil-images/mine/3atu) | Crystal structure of human Hsp70 NBD in the ADP- and Mg ion-bound state | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, ADENOSINE-5'-DIPHOSPHATE, Heat shock 70 kDa protein 1A/1B, ... | Authors: | Arakawa, A, Handa, N, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2011-01-13 | Release date: | 2011-12-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Biochemical and structural studies on the high affinity of Hsp70 for ADP. Protein Sci., 20, 2011
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3B98
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![BU of 3b98 by Molmil](/molmil-images/mine/3b98) | Crystal structure of zebrafish prostacyclin synthase (cytochrome P450 8A1) | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, Prostaglandin I2 synthase | Authors: | Li, Y.-C, Chiang, C.-W, Yeh, H.-C, Hsu, P.-Y, Whitby, F.G, Wang, L.-H, Chan, N.-L. | Deposit date: | 2007-11-03 | Release date: | 2007-11-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structures of Prostacyclin Synthase and Its Complexes with Substrate Analog and Inhibitor Reveal a Ligand-specific Heme Conformation Change J.Biol.Chem., 283, 2008
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1FQ1
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![BU of 1fq1 by Molmil](/molmil-images/mine/1fq1) | CRYSTAL STRUCTURE OF KINASE ASSOCIATED PHOSPHATASE (KAP) IN COMPLEX WITH PHOSPHO-CDK2 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CELL DIVISION PROTEIN KINASE 2, CYCLIN-DEPENDENT KINASE INHIBITOR 3, ... | Authors: | Song, H, Hanlon, N, Brown, N.R, Noble, M.E.M, Johnson, L.N, Barford, D. | Deposit date: | 2000-09-01 | Release date: | 2001-05-09 | Last modified: | 2018-03-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2. Mol.Cell, 7, 2001
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2ZR0
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![BU of 2zr0 by Molmil](/molmil-images/mine/2zr0) | MSRECA-Q196E mutant | Descriptor: | GLYCEROL, PHOSPHATE ION, Protein recA | Authors: | Prabu, J.R, Manjunath, G.P, Chandra, N.R, Muniyappa, K, Vijayan, M. | Deposit date: | 2008-08-22 | Release date: | 2008-12-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Functionally important movements in RecA molecules and filaments: studies involving mutation and environmental changes Acta Crystallogr.,Sect.D, 64, 2008
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