7YJJ
 
 | | Human Cytosolic 10-formyltetrahydrofolate dehydrogenase and Gossypol complex | | 分子名称: | Cytosolic 10-formyltetrahydrofolate dehydrogenase, Gossypol | | 著者 | Han, C.W, Lee, H.N, Jeong, M.S, Jang, S.B. | | 登録日 | 2022-07-20 | | 公開日 | 2023-07-26 | | 最終更新日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (6.31 Å) | | 主引用文献 | Structural identification and comprehension of human ALDH1L1-Gossypol complex.
Biochem.Biophys.Res.Commun., 726, 2024
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8I9J
 | | The PKR and E3L complex | | 分子名称: | Interferon-induced, double-stranded RNA-activated protein kinase, RNA-binding protein E3 | | 著者 | Han, C.W, Kim, H.J. | | 登録日 | 2023-02-07 | | 公開日 | 2023-06-28 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (6.39 Å) | | 主引用文献 | Structural study of novel vaccinia virus E3L and dsRNA-dependent protein kinase complex.
Biochem.Biophys.Res.Commun., 665, 2023
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8I9M
 | | The RAGE and HMGB1 complex | | 分子名称: | Advanced glycosylation end product-specific receptor, High mobility group protein B1 | | 著者 | Han, C.W, Kim, H.J. | | 登録日 | 2023-02-07 | | 公開日 | 2024-02-14 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (5.19 Å) | | 主引用文献 | The RAGE and HMGB1 complex
To Be Published
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8IZN
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8HGJ
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8J8N
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7C41
 | | KRAS G12V and H-REV107 peptide complex | | 分子名称: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, HRAS-like suppressor 3, ... | | 著者 | Han, C.W, Jeong, M.S, Jang, S.B. | | 登録日 | 2020-05-14 | | 公開日 | 2021-05-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.276 Å) | | 主引用文献 | A H-REV107 Peptide Inhibits Tumor Growth and Interacts Directly with Oncogenic KRAS Mutants.
Cancers (Basel), 12, 2020
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7C40
 | | MgGDP bound KRAS G12V | | 分子名称: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Han, C.W, Jeong, M.S, Jang, S.B. | | 登録日 | 2020-05-14 | | 公開日 | 2021-05-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.516 Å) | | 主引用文献 | A H-REV107 Peptide Inhibits Tumor Growth and Interacts Directly with Oncogenic KRAS Mutants.
Cancers (Basel), 12, 2020
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7C3Z
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7DVD
 | | The crystal structure of p53 DNA binding domain and PUMA complex | | 分子名称: | Bcl-2-binding component 3, isoforms 1/2, Cellular tumor antigen p53, ... | | 著者 | Han, C.W, Lee, H.N, Jeong, M.S, Jang, S.B. | | 登録日 | 2021-01-13 | | 公開日 | 2021-08-04 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Structural basis of the p53 DNA binding domain and PUMA complex.
Biochem.Biophys.Res.Commun., 548, 2021
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5ZJE
 | | LDHA-mla | | 分子名称: | L-lactate dehydrogenase A chain, MALONATE ION | | 著者 | Han, C.W, Jang, S.B. | | 登録日 | 2018-03-20 | | 公開日 | 2019-07-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.929 Å) | | 主引用文献 | Machilin A Inhibits Tumor Growth and Macrophage M2 Polarization Through the Reduction of Lactic Acid.
Cancers (Basel), 11, 2019
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5ZJF
 | | LDHA-MA | | 分子名称: | 5,5'-[(2R,3S)-2,3-dimethylbutane-1,4-diyl]bis(2H-1,3-benzodioxole), L-lactate dehydrogenase A chain | | 著者 | Han, C.W, Jang, S.B. | | 登録日 | 2018-03-20 | | 公開日 | 2019-07-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.602 Å) | | 主引用文献 | Machilin A Inhibits Tumor Growth and Macrophage M2 Polarization Through the Reduction of Lactic Acid.
Cancers (Basel), 11, 2019
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5ZJD
 | | Lactate dehydrogenase with NADH and MLA | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-lactate dehydrogenase A chain, MALONATE ION | | 著者 | Han, C.W, Jang, S.B. | | 登録日 | 2018-03-20 | | 公開日 | 2019-07-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.394 Å) | | 主引用文献 | Machilin A Inhibits Tumor Growth and Macrophage M2 Polarization Through the Reduction of Lactic Acid.
Cancers (Basel), 11, 2019
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7W5Q
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7LJP
 | | Structure of Thermotoga maritima SmpB | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, GLYCEROL, SULFATE ION, ... | | 著者 | Chan, C.W, Mondragon, A. | | 登録日 | 2021-01-29 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of Thermotoga maritima SmpB reveals its C-terminal tail domain in a helical conformation mimicking that of a ribosome-bound state
To Be Published
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6UGJ
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6UGG
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6UGI
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6VMY
 | | Structure of the B. subtilis cobalamin riboswitch | | 分子名称: | Adenosylcobalamin, B. subtilis cobalamin riboswitch, COBALT HEXAMMINE(III), ... | | 著者 | Chan, C.W, Mondragon, A. | | 登録日 | 2020-01-28 | | 公開日 | 2020-06-10 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Crystal structure of an atypical cobalamin riboswitch reveals RNA structural adaptability as basis for promiscuous ligand binding.
Nucleic Acids Res., 48, 2020
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4ZQA
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6CWX
 | | Crystal structure of human ribonuclease P/MRP proteins Rpp20/Rpp25 | | 分子名称: | FORMIC ACID, Ribonuclease P protein subunit p20, Ribonuclease P protein subunit p25, ... | | 著者 | Chan, C.W, Kiesel, B.R, Mondragon, A. | | 登録日 | 2018-03-31 | | 公開日 | 2018-04-18 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystal Structure of Human Rpp20/Rpp25 Reveals Quaternary Level Adaptation of the Alba Scaffold as Structural Basis for Single-stranded RNA Binding.
J. Mol. Biol., 430, 2018
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7W5R
 | | KRAS G12V and peptide complex | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, LEU-TYR-ASP-VAL-ALA, ... | | 著者 | Kim, H.J, Han, C.W, Jang, S.B. | | 登録日 | 2021-11-30 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.87 Å) | | 主引用文献 | Structural basis of the oncogenic KRAS mutant and GJ101 complex.
Biochem.Biophys.Res.Commun., 641, 2023
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5GRJ
 | | Crystal structure of human PD-L1 with monoclonal antibody avelumab | | 分子名称: | Programmed cell death 1 ligand 1, avelumab H chain, avelumab L chain | | 著者 | Liu, K, Tan, S, Chai, Y, Chen, D, Song, H, Zhang, C.W.-H, Shi, Y, Liu, J, Tan, W, Lyu, J, Gao, S, Yan, J, Qi, J, Gao, G.F. | | 登録日 | 2016-08-11 | | 公開日 | 2016-11-02 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.206 Å) | | 主引用文献 | Structural basis of anti-PD-L1 monoclonal antibody avelumab for tumor therapy.
Cell Res., 27, 2017
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5D90
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5E01
 | | Crystal structure of HiNmlR, a MerR family regulator lacking the sensor domain, bound to palyndromic promoter DNA | | 分子名称: | 5'-D(*CP*TP*TP*AP*GP*AP*GP*TP*GP*CP*AP*CP*TP*CP*TP*AP*AP*G)-3', Uncharacterized HTH-type transcriptional regulator HI_0186 | | 著者 | Counago, R.M, Chang, C.W, Chen, N.H, Djoko, K.Y, McEwan, A.G, Kobe, B. | | 登録日 | 2015-09-26 | | 公開日 | 2016-06-29 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region.
Nucleic Acids Res., 44, 2016
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