1AT0
 
 | | 17-kDA fragment of hedgehog C-terminal autoprocessing domain | | 分子名称: | 17-HEDGEHOG | | 著者 | Hall, T.M.T, Porter, J.A, Young, K.E, Koonin, E.V, Beachy, P.A, Leahy, D.J. | | 登録日 | 1997-08-15 | | 公開日 | 1997-11-12 | | 最終更新日 | 2017-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of a Hedgehog autoprocessing domain: homology between Hedgehog and self-splicing proteins.
Cell(Cambridge,Mass.), 91, 1997
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1VHH
 | | A POTENTIAL CATALYTIC SITE WITHIN THE AMINO-TERMINAL SIGNALLING DOMAIN OF SONIC HEDGEHOG | | 分子名称: | SONIC HEDGEHOG, SULFATE ION, ZINC ION | | 著者 | Hall, T.M.T, Porter, J.A, Beachy, P.A, Leahy, D.J. | | 登録日 | 1995-10-03 | | 公開日 | 1996-01-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | A potential catalytic site revealed by the 1.7-A crystal structure of the amino-terminal signalling domain of Sonic hedgehog.
Nature, 378, 1995
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5UZG
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6LVR
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7TU0
 | | Structure of the L. blandensis dGTPase bound to Mn | | 分子名称: | MANGANESE (II) ION, SULFATE ION, dGTP triphosphohydrolase | | 著者 | Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T. | | 登録日 | 2022-02-02 | | 公開日 | 2022-06-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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7TU1
 | | Structure of the L. blandensis dGTPase R37A mutant | | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, dGTP triphosphohydrolase | | 著者 | Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T. | | 登録日 | 2022-02-02 | | 公開日 | 2022-06-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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7TU2
 | | Structure of the L. blandensis dGTPase R37A mutant bound to Mn | | 分子名称: | MANGANESE (II) ION, SULFATE ION, dGTP triphosphohydrolase | | 著者 | Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T. | | 登録日 | 2022-02-02 | | 公開日 | 2022-06-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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7TU3
 | | Structure of the L. blandensis dGTPase del55-58 mutant | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, SULFATE ION, ... | | 著者 | Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T. | | 登録日 | 2022-02-02 | | 公開日 | 2022-06-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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7TU4
 | | Structure of the L. blandensis dGTPase del55-58 mutant bound to Mn | | 分子名称: | 1,2-ETHANEDIOL, MANGANESE (II) ION, SULFATE ION, ... | | 著者 | Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T. | | 登録日 | 2022-02-02 | | 公開日 | 2022-06-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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4WZW
 | | Crystal structure of human Puf-A in complex with DNA | | 分子名称: | DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3'), DNA (5'-D(P*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), Pumilio domain-containing protein KIAA0020 | | 著者 | Qiu, C, Hall, T.M.T. | | 登録日 | 2014-11-20 | | 公開日 | 2014-12-31 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.9516 Å) | | 主引用文献 | A divergent Pumilio repeat protein family for pre-rRNA processing and mRNA localization.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4WZR
 | | Crystal structure of human Puf-A | | 分子名称: | GLYCEROL, Pumilio domain-containing protein KIAA0020 | | 著者 | Qiu, C, Hall, T.M.T. | | 登録日 | 2014-11-20 | | 公開日 | 2014-12-31 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.154 Å) | | 主引用文献 | A divergent Pumilio repeat protein family for pre-rRNA processing and mRNA localization.
Proc.Natl.Acad.Sci.USA, 111, 2014
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6WPI
 | | Crystal structure of Nop9 in complex with ITS1 RNA | | 分子名称: | 3,3',3''-phosphanetriyltripropanoic acid, GLYCEROL, Nucleolar protein 9, ... | | 著者 | Zhang, J, Qiu, C, Hall, T.M.T. | | 登録日 | 2020-04-27 | | 公開日 | 2020-05-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | | 主引用文献 | Nop9 recognizes structured and single-stranded RNA elements of preribosomal RNA.
Rna, 26, 2020
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6NOH
 | | Crystal structure of FBF-2 repeat 5 mutant (C363S, R364Y, Q367S) in complex with 8-nt RNA | | 分子名称: | 1,2-ETHANEDIOL, Fem-3 mRNA-binding factor 2, RNA (5'-R(*UP*GP*UP*AP*AP*AP*UP*A)-3') | | 著者 | McCann, K.L, Wang, Y, Qiu, C, Hall, T.M.T. | | 登録日 | 2019-01-16 | | 公開日 | 2019-01-30 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.249 Å) | | 主引用文献 | Engineering a conserved RNA regulatory protein repurposes its biological function in vivo .
Elife, 8, 2019
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6NOF
 | | Crystal structure of FBF-2 repeat 5 mutant (C363A, R364Y, Q367S) in complex with 8-nt RNA | | 分子名称: | 1,2-ETHANEDIOL, Fem-3 mRNA-binding factor 2, RNA (5'-R(*UP*GP*UP*AP*AP*AP*UP*A)-3') | | 著者 | McCann, K.L, Wang, Y, Qiu, C, Hall, T.M.T. | | 登録日 | 2019-01-16 | | 公開日 | 2019-01-30 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.251 Å) | | 主引用文献 | Engineering a conserved RNA regulatory protein repurposes its biological function in vivo .
Elife, 8, 2019
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6NOC
 | | Crystal structure of FBF-2 repeat 5 mutant (C363A, R364Y) in complex with 8-nt RNA | | 分子名称: | Fem-3 mRNA-binding factor 2, RNA (5'-R(*UP*GP*UP*AP*AP*AP*UP*A)-3') | | 著者 | McCann, K, Wang, Y, Qiu, C, Hall, T.M.T. | | 登録日 | 2019-01-16 | | 公開日 | 2019-01-30 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.849 Å) | | 主引用文献 | Engineering a conserved RNA regulatory protein repurposes its biological function in vivo .
Elife, 8, 2019
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6NOD
 | | Crystal structure of C. elegans PUF-8 in complex with RNA | | 分子名称: | PUF (Pumilio/FBF) domain-containing, RNA (5'-R(P*UP*GP*UP*AP*UP*AP*UP*A)-3') | | 著者 | Wang, Y, McCann, K.L, Qiu, C, Hall, T.M.T. | | 登録日 | 2019-01-16 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.547 Å) | | 主引用文献 | Engineering a conserved RNA regulatory protein repurposes its biological function in vivo .
Elife, 8, 2019
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5KL1
 | | Crystal structure of the Pumilio-Nos-hunchback RNA complex | | 分子名称: | Maternal protein pumilio, Protein nanos, RNA (5'-R(*AP*AP*AP*UP*UP*GP*UP*AP*CP*AP*UP*A)-3'), ... | | 著者 | Qiu, C, Hall, T.M.T. | | 登録日 | 2016-06-23 | | 公開日 | 2016-08-17 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.701 Å) | | 主引用文献 | Drosophila Nanos acts as a molecular clamp that modulates the RNA-binding and repression activities of Pumilio.
Elife, 5, 2016
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5KLA
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8DGA
 | | Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex IV | | 分子名称: | Endoribonuclease Dcr-1, Loquacious, isoform B, ... | | 著者 | Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A. | | 登録日 | 2022-06-23 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | | 主引用文献 | Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
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5KL8
 | | Crystal structure of the Pumilio-Nos-CyclinB RNA complex | | 分子名称: | Maternal protein pumilio, Protein nanos, RNA (5'-R(*UP*AP*UP*UP*UP*GP*UP*AP*AP*UP*U)-3'), ... | | 著者 | Qiu, C, Hall, T.M.T. | | 登録日 | 2016-06-23 | | 公開日 | 2016-08-17 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | Drosophila Nanos acts as a molecular clamp that modulates the RNA-binding and repression activities of Pumilio.
Elife, 5, 2016
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8DG7
 | | Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex III | | 分子名称: | Endoribonuclease Dcr-1, Loquacious, isoform B, ... | | 著者 | Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A. | | 登録日 | 2022-06-23 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | | 主引用文献 | Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
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8DFV
 | | Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex IIa | | 分子名称: | CALCIUM ION, Endoribonuclease Dcr-1, Loquacious, ... | | 著者 | Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A. | | 登録日 | 2022-06-22 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | | 主引用文献 | Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
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8DGJ
 | | Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex Ib | | 分子名称: | Endoribonuclease Dcr-1, Loquacious, isoform B | | 著者 | Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A. | | 登録日 | 2022-06-23 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (4.02 Å) | | 主引用文献 | Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
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8DG5
 | | Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex IIb | | 分子名称: | Endoribonuclease Dcr-1, Loquacious, isoform B, ... | | 著者 | Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A. | | 登録日 | 2022-06-23 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
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8DGI
 | | Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex Ia | | 分子名称: | Endoribonuclease Dcr-1, Loquacious, isoform B | | 著者 | Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A. | | 登録日 | 2022-06-23 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.94 Å) | | 主引用文献 | Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
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