7UXL
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![BU of 7uxl by Molmil](/molmil-images/mine/7uxl) | Crystal structure of malaria transmission-blocking antigen Pfs48/45-6C variant in complex with human antibodies RUPA-44 and RUPA-29 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Gametocyte surface protein P45/48, RUPA-29 Fab Heavy chain, ... | Authors: | Hailemariam, S, Ivanochko, D, Julien, J.P. | Deposit date: | 2022-05-05 | Release date: | 2023-02-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Highly potent, naturally acquired human monoclonal antibodies against Pfs48/45 block Plasmodium falciparum transmission to mosquitoes. Immunity, 56, 2023
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7UNB
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![BU of 7unb by Molmil](/molmil-images/mine/7unb) | Crystal structure of malaria transmission-blocking antigen Pfs48/45-6C variant in complex with human antibodies RUPA-117 and RUPA-47 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Gametocyte surface protein P45/48, RUPA-117 Fab heavy chain, ... | Authors: | Hailemariam, S, McLeod, B, Julien, J.-P. | Deposit date: | 2022-04-10 | Release date: | 2022-08-10 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses. Immunity, 55, 2022
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1TOW
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![BU of 1tow by Molmil](/molmil-images/mine/1tow) | Crystal structure of human adipocyte fatty acid binding protein in complex with a carboxylic acid ligand | Descriptor: | 4-(9H-CARBAZOL-9-YL)BUTANOIC ACID, Fatty acid-binding protein, adipocyte | Authors: | Lehmann, F, Haile, S, Axen, E, Medina, C, Uppenberg, J, Svensson, S, Lundback, T, Rondahl, L, Barf, T. | Deposit date: | 2004-06-15 | Release date: | 2004-08-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target. Bioorg.Med.Chem.Lett., 14, 2004
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5EWO
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![BU of 5ewo by Molmil](/molmil-images/mine/5ewo) | Crystal structure of the human astrovirus 1 capsid protein spike domain at 0.95-A resolution | Descriptor: | SULFATE ION, Structural protein | Authors: | Bogdanoff, W, York, R.L, Yousefi, P.A, Haile, S, Tripathi, S, DuBois, R.M. | Deposit date: | 2015-11-20 | Release date: | 2015-12-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | Structural, Mechanistic, and Antigenic Characterization of the Human Astrovirus Capsid. J.Virol., 90, 2015
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5EWN
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![BU of 5ewn by Molmil](/molmil-images/mine/5ewn) | Crystal structure of the human astrovirus 1 capsid protein core domain at 2.6 A resolution | Descriptor: | CHLORIDE ION, Structural protein | Authors: | York, R.L, Yousefi, P.A, Bogdanoff, W, Haile, S, Tripathi, S, DuBois, R.M. | Deposit date: | 2015-11-20 | Release date: | 2015-12-23 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (2.602 Å) | Cite: | Structural, Mechanistic, and Antigenic Characterization of the Human Astrovirus Capsid. J.Virol., 90, 2015
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3FR2
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![BU of 3fr2 by Molmil](/molmil-images/mine/3fr2) | N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte Fatty-Acid Binding Protein (A-FABP) inhibitors | Descriptor: | 9-benzyl-2,3,4,9-tetrahydro-1H-carbazole-8-carboxylic acid, Fatty acid-binding protein, adipocyte | Authors: | Barf, T, Hammer, K, Lehmann, F, Haile, S, Axen, E, Medina, C, Rondahl, L, Uppenberg, J, Svensson, S, Lundb ck, T. | Deposit date: | 2009-01-08 | Release date: | 2009-03-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte fatty-acid binding protein (A-FABP) inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
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3FR5
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![BU of 3fr5 by Molmil](/molmil-images/mine/3fr5) | N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte Fatty-Acid Binding Protein (A-FABP) inhibitors | Descriptor: | 5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acid, Fatty acid-binding protein, adipocyte | Authors: | Barf, T, Hammer, K, Lehmann, F, Haile, S, Axen, E, Medina, C, Uppenberg, J, Svensson, S, Rondahl, L, Lundb ck, T. | Deposit date: | 2009-01-08 | Release date: | 2009-03-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte fatty-acid binding protein (A-FABP) inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
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3FR4
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![BU of 3fr4 by Molmil](/molmil-images/mine/3fr4) | N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte Fatty-Acid Binding Protein (A-FABP) inhibitors | Descriptor: | 9-[2-(trifluoromethyl)benzyl]-2,3,4,9-tetrahydro-1H-carbazole-8-carboxylic acid, Fatty acid-binding protein, adipocyte | Authors: | Barf, T, Hammer, K, Lehmann, F, Haile, S, Axen, E, Medina, C, Uppenberg, J, Svensson, S, Rondahl, L, Lundb ck, T. | Deposit date: | 2009-01-08 | Release date: | 2009-03-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte fatty-acid binding protein (A-FABP) inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
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