1TOW

Crystal structure of human adipocyte fatty acid binding protein in complex with a carboxylic acid ligand

Summary for 1TOW

Entry DOI	10.2210/pdb1tow/pdb
Related	1TOU
Descriptor	Fatty acid-binding protein, adipocyte, 4-(9H-CARBAZOL-9-YL)BUTANOIC ACID (3 entities in total)
Functional Keywords	transport, lipid-binding, lipid transport
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P15090
Total number of polymer chains	1
Total formula weight	14862.00
Authors	Lehmann, F.,Haile, S.,Axen, E.,Medina, C.,Uppenberg, J.,Svensson, S.,Lundback, T.,Rondahl, L.,Barf, T. (deposition date: 2004-06-15, release date: 2004-08-24, Last modification date: 2024-03-13)
Primary citation	Lehmann, F.,Haile, S.,Axen, E.,Medina, C.,Uppenberg, J.,Svensson, S.,Lundback, T.,Rondahl, L.,Barf, T. Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target. Bioorg.Med.Chem.Lett., 14:4445-4448, 2004 Cited by PubMed: 15357969 DOI: 10.1016/j.bmcl.2004.06.057 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation