1DYE
 
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5ZCX
 | | Structure of T20/N39 | | Descriptor: | Envelope glycoprotein, Envelope glycoprotein gp160 | | Authors: | Zhang, X.J, Ding, X.H. | | Deposit date: | 2018-02-21 | | Release date: | 2018-10-10 | | Last modified: | 2018-12-19 | | Method: | X-RAY DIFFRACTION (2.299 Å) | | Cite: | Structural and functional characterization of HIV-1 cell fusion inhibitor T20.
AIDS, 33, 2019
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5ZII
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8IEW
 | | Cas005-crRNA-DNA complex | | Descriptor: | Cas005, DNA (55-MER), RNA (38-MER) | | Authors: | Zhang, X, Duan, Z.Q, Zhu, J.K. | | Deposit date: | 2023-02-16 | | Release date: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Cryo-EM structure of Cas005-crRNA-DNA complex at 3.1 Angstroms resolution
To Be Published
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8INB
 | | Cryo-EM structure of Cas12j-SF05-crRNA-dsDNA complex | | Descriptor: | Cas12j-SF05, NTS-DNA, TS-DNA, ... | | Authors: | Zhang, X, Duan, Z.Q, Zhu, J.K. | | Deposit date: | 2023-03-09 | | Release date: | 2024-03-13 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Molecular basis for DNA cleavage by the hypercompact Cas12j-SF05.
Cell Discov, 9, 2023
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1CDZ
 | | BRCT DOMAIN FROM DNA-REPAIR PROTEIN XRCC1 | | Descriptor: | PROTEIN (DNA-REPAIR PROTEIN XRCC1) | | Authors: | Zhang, X, Morera, S, Bates, P, Whitehead, P, Coffer, A, Hainbucher, K, Nash, R, Sternberg, M, Lindahl, T, Freemont, P. | | Deposit date: | 1999-03-04 | | Release date: | 2000-02-28 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure of an XRCC1 BRCT domain: a new protein-protein interaction module.
EMBO J., 17, 1998
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3J2P
 | | CryoEM structure of Dengue virus envelope protein heterotetramer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ... | | Authors: | Zhang, X, Ge, P, Yu, X, Brannan, J.M, Bi, G, Zhang, Q, Schein, S, Zhou, Z.H. | | Deposit date: | 2012-11-30 | | Release date: | 2012-12-19 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM structure of the mature dengue virus at 3.5-A resolution.
Nat.Struct.Mol.Biol., 20, 2012
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3X3M
 | | Crystal structure of EccB1 of Mycobacterium tuberculosis in spacegroup P212121 | | Descriptor: | CALCIUM ION, ESX-1 secretion system protein EccB1 | | Authors: | Zhang, X.L, Li, D.F, Zhang, X.E, Bi, L.J, Wang, D.C. | | Deposit date: | 2015-01-24 | | Release date: | 2015-12-09 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Core component EccB1 of the Mycobacterium tuberculosis type VII secretion system is a periplasmic ATPase.
Faseb J., 29, 2015
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3X3N
 | | Crystal structure of EccB1 of Mycobacterium tuberculosis in spacegroup P21 | | Descriptor: | CALCIUM ION, ESX-1 secretion system protein EccB1 | | Authors: | Zhang, X.L, Li, D.F, Zhang, X.E, Bi, L.J, Wang, D.C. | | Deposit date: | 2015-01-24 | | Release date: | 2015-12-09 | | Last modified: | 2022-08-24 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Core component EccB1 of the Mycobacterium tuberculosis type VII secretion system is a periplasmic ATPase.
Faseb J., 29, 2015
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1F3L
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1HQK
 | | CRYSTAL STRUCTURE ANALYSIS OF LUMAZINE SYNTHASE FROM AQUIFEX AEOLICUS | | Descriptor: | 6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE | | Authors: | Zhang, X, Meining, W, Fischer, M, Bacher, A, Ladenstein, R. | | Deposit date: | 2000-12-18 | | Release date: | 2001-12-18 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | X-ray structure analysis and crystallographic refinement of lumazine synthase from the hyperthermophile Aquifex aeolicus at 1.6 A resolution: determinants of thermostability revealed from structural comparisons.
J.Mol.Biol., 306, 2001
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6IWI
 | | Crystal structure of PDE5A in complex with a novel inhibitor | | Descriptor: | MAGNESIUM ION, N-[3-(4,5-diethyl-6-oxo-1,6-dihydropyrimidin-2-yl)-4-propoxyphenyl]-2-(4-methylpiperazin-1-yl)acetamide, ZINC ION, ... | | Authors: | Zhang, X.L, Xu, Y.C. | | Deposit date: | 2018-12-05 | | Release date: | 2019-12-11 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.155 Å) | | Cite: | Pharmacokinetics-Driven Optimization of 4(3 H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension.
J.Med.Chem., 62, 2019
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6J4M
 | | Thermal treated soybean seed H-2 ferritin | | Descriptor: | Ferritin, MAGNESIUM ION | | Authors: | Zhang, X, Zang, J, Chen, H, Zhou, K, Zhao, G. | | Deposit date: | 2019-01-09 | | Release date: | 2019-09-18 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.598 Å) | | Cite: | Thermostability of protein nanocages: the effect of natural extra peptide on the exterior surface.
Rsc Adv, 9, 2019
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3F4M
 | | Crystal structure of TIPE2 | | Descriptor: | CHLORIDE ION, Tumor necrosis factor, alpha-induced protein 8-like protein 2 | | Authors: | Zhang, X, Wang, J, Shi, Y. | | Deposit date: | 2008-11-01 | | Release date: | 2009-03-17 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.696 Å) | | Cite: | Crystal structure of TIPE2 provides insights into immune homeostasis
Nat.Struct.Mol.Biol., 16, 2009
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3J26
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3J8D
 | | Cryoelectron microscopy of dengue-Fab E104 complex at pH 5.5 | | Descriptor: | Envelope protein E, antibody E111 Fab fragment, glycoprotein DIII | | Authors: | Zhang, X.Z, Sheng, J, Austin, S.K, Hoornweg, T, Smit, J.M, Kuhn, R.J, Diamond, M.S, Rossmann, M.G. | | Deposit date: | 2014-10-13 | | Release date: | 2014-11-12 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (26 Å) | | Cite: | Structure of Acidic pH Dengue Virus Showing the Fusogenic Glycoprotein Trimers.
J.Virol., 89, 2015
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5Z1V
 | | Crystal structure of AvrPib | | Descriptor: | AvrPib protein | | Authors: | Zhang, X, He, D, Zhao, Y.X, Taylor, I.A, Peng, Y.L, Yang, J, Liu, J.F. | | Deposit date: | 2017-12-28 | | Release date: | 2018-09-05 | | Last modified: | 2018-10-03 | | Method: | X-RAY DIFFRACTION (1.661 Å) | | Cite: | A positive-charged patch and stabilized hydrophobic core are essential for avirulence function of AvrPib in the rice blast fungus.
Plant J., 96, 2018
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1AI0
 | | R6 HUMAN INSULIN HEXAMER (NON-SYMMETRIC), NMR, 10 STRUCTURES | | Descriptor: | PHENOL, R6 INSULIN HEXAMER, ZINC ION | | Authors: | Chang, X, Jorgensen, A.M.M, Bardrum, P, Led, J.J. | | Deposit date: | 1997-04-30 | | Release date: | 1997-11-12 | | Last modified: | 2022-02-16 | | Method: | SOLUTION NMR | | Cite: | Solution structures of the R6 human insulin hexamer.
Biochemistry, 36, 1997
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1AIY
 | | R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 10 STRUCTURES | | Descriptor: | PHENOL, R6 INSULIN HEXAMER, ZINC ION | | Authors: | Chang, X, Jorgensen, A.M.M, Bardrum, P, Led, J.J. | | Deposit date: | 1997-04-30 | | Release date: | 1997-11-12 | | Last modified: | 2022-02-16 | | Method: | SOLUTION NMR | | Cite: | Solution structures of the R6 human insulin hexamer.
Biochemistry, 36, 1997
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5Z93
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3J9D
 | | Atomic structure of a non-enveloped virus reveals pH sensors for a coordinated process of cell entry | | Descriptor: | Outer capsid protein VP2, ZINC ION | | Authors: | Zhang, X, Patel, A, Celma, C, Roy, P, Zhou, Z.H. | | Deposit date: | 2015-01-09 | | Release date: | 2015-12-09 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Atomic model of a nonenveloped virus reveals pH sensors for a coordinated process of cell entry.
Nat.Struct.Mol.Biol., 23, 2016
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1L71
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8I0V
 | | The cryo-EM structure of human post-Bact complex | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... | | Authors: | Zhan, X, Lu, Y, Shi, Y. | | Deposit date: | 2023-01-11 | | Release date: | 2024-07-31 | | Last modified: | 2024-08-07 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
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8I0P
 | | The cryo-EM structure of human pre-Bact complex | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | | Authors: | Zhan, X, Lu, Y, Shi, Y. | | Deposit date: | 2023-01-11 | | Release date: | 2024-07-31 | | Last modified: | 2024-08-07 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
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8I0W
 | | The cryo-EM structure of human C complex | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Coiled-coil domain-containing protein 94, ... | | Authors: | Zhan, X, Lu, Y, Shi, Y. | | Deposit date: | 2023-01-11 | | Release date: | 2024-07-31 | | Last modified: | 2024-08-07 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
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